Factors Affecting the Progression of Diabetic Nephropathy and its Complications: A Single-center Experience in Saudi Arabia
CONCLUSION: Diabetic nephropathy tends to be progressive among Saudis, with GFR deteriorating at a rate of 3.3 mL/year and with a doubling of serum creatinine level in 40.3% of patients in 9.9 years. Ann Saudi Med 2011; 31(3): 236-242PMID: 21623051 DOI: 10.4103/0256-4947.81528 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research

Effect of Thyroid Hormone Replacement Therapy on Ovarian Volume and Androgen Hormones in Patients with Untreated Primary Hypothyroidism
CONCLUSION: Severe longstanding hypothyroidism leads to increased ovarian volume and/or cyst formation. A decrease in ovarian volume, resolution of ovarian cysts and reversal of the polycystic ovary syndrome-like appearance, together with improvement in serum hormone levels, occurred after euthyroidism was achieved. Ann Saudi Med 2011; 31(2): 145-151PMID: 21403408 DOI: 10.4103/0256-4947.77500 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Chronic Spontaneous Cervicothoracic Epidural Hematoma in an 8-month-old Infant
We present the case to highlight the significance of recognizing this chronic spontaneous spinal epidural hematoma and discuss the diagnosis, treatment options and prognosis. Ann Saudi Med 2011; 31(3): 301-304PMID: 21242640 DOI: 10.4103/0256-4947.75586 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research

Betel Nut Chewing as a Risk Factor for Hepatitis C Infection in Taiwan-a Community-Based Study
  To the Editor: We completed a comprehensive health survey and structural questionnaires among the adults living in the eastern area of Taichung (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Erratum
  The order of authors in the article below should have appeared as: Mohammad Alsharani, Marzouqah Alanazi, Majid Alsalamah  Alanazi M, Alashahrani M, Alsalamah M. Black (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Reply
  Thank you for the comments. My response is as follows:  The comments on relapse usually occurring in two to three weeks after the infection (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

MRI Demonstration of Subtotal Agenesis of the Cerebellum with Closed-Lip Schizencephaly
Ann Saudi Med 2011; 31(2): 207-208PMID: 21422661 DOI: 10.4103/0256-4947.78212 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Unusual Anatomic Location of a Primary Intracranial Yolk Sac Tumor
A nongerminomatous germ cell tumor occurring in the brain parenchyma is extremely rare. A 2-year-old boy presented with symptoms of abnormal movements in the hand and mouth. MRI scanning revealed a lesion occupying the left temporoparietal region. Craniotomy was performed and the tumor was removed by en bloc resection. Histological examination revealed that the tumor was arranged in a reticular pattern, and Schiller-Duval bodies were evident at the center of the tumor. Immunohistochemical study showed that the tumor cells were positive for alpha-fetoprotein and vimentin, but negative for glial fibrillary acidic protein. Th...
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research

Cyst in the Liver and Cough with Copious Purulent Sputum
Ann Saudi Med 2011 ; 31 (2): 206PMID: 21403405 DOI: 10.4103/0256-4947.77504 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Prevalence of Gilbert Syndrome in Parents of Neonates with Pathologic Indirect Hyperbilirubinemia
CONCLUSION: This study showed that GS cannot cause severe indirect hyperbilirubinemia by itself, but it may have a summative effect on rising bilirubin when combined with other factors, for example, G6PD. Our results showed that in GS, males are affected about twice as much as the females. Ann Saudi Med 2011; 31(2): 140-144PMID: 21403409 DOI: 10.4103/0256-4947.77498 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Distribution of Chronotypes in a Large Sample of Young Adult Saudis
CONCLUSION: Most Saudi college students had no preference for morningness or eveningness and were classified as " intermediate-types. " Morningness appears to be slightly more common in Saudis, especially males, than in individuals of some Western societies. Ann Saudi Med 2011; 31(2): 183-186PMID: 21422657 DOI: 10.4103/0256-4947.78207 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Characteristics of Human Ewing/PNET Sarcoma Models
Ewing/PNET (peripheral neuroepithelioma) tumors are rare aggressive bone sarcomas occurring in young people. Rare-disease clinical trials can require global collaborations and many years. In vivo models that as accurately as possible reflect the clinical disease are helpful in selecting therapeutics with the most promise of positive clinical impact. Human Ewing/PNET sarcoma cell lines developed over the past 45 years are described. Several of these have undergone genetic analysis and have been confirmed to be those of Ewing/PNET sarcoma. The A673 Ewing sarcoma line has proven to be particularly useful in understanding the ...
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Incidence of Various Clinico-Morphological Variants of Cutaneous Tuberculosis and HIV Concurrence: A Study from the Indian Subcontinent
CONCLUSIONS:Cutaneous tuberculosis rates were slightly higher in our study than in other studies from India. HIV co-infection rates were similar to those in other studies. Many atypical morphological forms and presentations were observed in HIV co-infected patients. Due to the varied clinical presentations, physician awareness and a high index of suspicion are necessary to diagnose cutaneous forms of tuberculosis. Ann Saudi Med 2011 ; 31 (2): 1 34-1 39PMID: 21403410 DOI: 10.4103/0256-4947.77495 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research

Percutaneous Vertebroplasty Complications
Percutaneous vertebroplasty, among various other options, has become a mainstay in the management of osteoporotic and malignant vertebral fractures. The purpose of this article is to describe complications arising from the procedure, which can be classified as mild, which may include a temporary increase in pain and transient hypotension; moderate, including infection and extravasation of cement into the foraminal, epidural or dural space; and severe such as cement leakage in the paravertebral veins, leading to pulmonary embolism, cardiac perforation, cerebral embolism or even death. Vertebroplasty is not a procedure witho...
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research

Re-Infection of Typhoid Fever and Typhoid Vaccine (Comment on " An Imported Enteric Fever Caused by a Quinolone-Resistant Salmonella Typhi " )
PMID: 21403404DOI: 10.4103/0256-4947.77505 (Source: Annals of Saudi Medicine)
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 2 Source Type: research