Real-world predictors of divorce among outpatients with bipolar disorder: sex differences and clinical implications
Bipolar disorder is a mental illness characterized by recurring episodes of mania and depression and is known to cause social impairment. Additionally, it has been revealed that bipolar disorder increases the ... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 12, 2023 Category: Psychiatry Authors: Keita Tokumitsu, Norio Sugawara, Naoto Adachi, Yukihisa Kubota, Yoichiro Watanabe, Kazuhira Miki, Takaharu Azekawa, Koji Edagawa, Eiichi Katsumoto, Seiji Hongo, Eiichiro Goto, Hitoshi Ueda, Masaki Kato, Reiji Yoshimura, Atsuo Nakagawa, Toshiaki Kikuchi & Tags: Research Source Type: research
Sex difference in incidence of major depressive disorder: an analysis from the Global Burden of Disease Study 2019
This study was aimed to evaluate sex difference in global MDD incidence by year, age, and socioeconomic status, according... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 12, 2023 Category: Psychiatry Authors: Sangzi Li, Xuan Zhang, Yilu Cai, Leilei Zheng, Hu Pang and Lixia Lou Tags: Research Source Type: research
Facts and myths about the use of lithium for bipolar disorder in routine clinical practice: an expert consensus paper
Bipolar disorder is one of the most burdensome severe mental disorders, characterized by high levels of personal and social disability. Patients often need an integrated pharmacological and non-pharmacological... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 6, 2023 Category: Psychiatry Authors: Andrea Fiorillo, Gaia Sampogna, Umberto Albert, Giuseppe Maina, Giulio Perugi, Maurizio Pompili, Gianluca Rosso, Gabriele Sani and Alfonso Tortorella Tags: Review Source Type: research
Clinical characteristics of suicidal behavior in first hospitalization and drug-na ïve patients with major depressive disorder
Major depressive disorder (MDD) is a major and common cause of suicide. The purpose of this article is to report the clinical characteristics and patterns of co-morbid suicidal behavior (SB) in first hospitali... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 6, 2023 Category: Psychiatry Authors: Xianzhi Sun, Lili Yin, Yingying Zhang, Xuebing Liu and Jun Ma Tags: Research Source Type: research
Discontinuation of antidepressant treatment: a retrospective cohort study on more than 20,000 participants
Factors influencing antidepressant treatment discontinuation are poorly understood. In the present study, we aimed to estimate the prevalence of antidepressant treatment discontinuation and identify demographi... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 24, 2023 Category: Psychiatry Authors: Luis M. Garcia-Marin, Aoibhe Mulcahy, Enda M. Byrne, Sarah E. Medland, Naomi R. Wray, Freddy Chafota, Penelope A. Lind, Nicholas G. Martin, Ian B. Hickie, Miguel E. Renter ía and Adrian I. Campos Tags: Research Source Type: research
Mendelian randomization studies of depression: evidence, opportunities, and challenges
Major depressive disorder (MDD) poses a significant social and economic burden worldwide. Identifying exposures, risk factors, and biological mechanisms that are causally connected to MDD can help build a scie... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 23, 2023 Category: Psychiatry Authors: Wang-ran Ma, Lei-lei Zhang, Jing-ying Ma, Fang Yu, Ya-qing Hou, Xiang-rui Feng and Lin Yang Tags: Review Source Type: research
Nationwide consensus on the clinical management of treatment-resistant depression in Italy: a Delphi panel
Treatment-resistant depression (TRD) is defined by the European Medicines Agency as a lack of clinically meaningful improvement after treatment, with at least two different antidepressants. Individual, familia... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 23, 2023 Category: Psychiatry Authors: Giuseppe Maina, Marina Adami, Giuseppe Ascione, Emi Bondi, Domenico De Berardis, Dario Delmonte, Silvia Maffezzoli, Giovanni Martinotti, Alessandra Nivoli, Elena Ottavianelli and Andrea Fagiolini Tags: Research Source Type: research
A multicenter, randomized controlled study on the efficacy of agomelatine in ameliorating anhedonia, reduced motivation, and circadian rhythm disruptions in patients with major depressive disorder (MDD)
To evaluate the clinical efficacy and safety of Agomelatine in improving symptoms in patients with major depressive disorder (MDD), providing more scientific evidence for the treatment of depression, and offer... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 13, 2023 Category: Psychiatry Authors: Ping Guo, Yong Xu, Liang Lv, Min Feng, Yu Fang, Wei-Quan Huang, Shan-Fei Cheng, Min-Cai Qian, Shengliang Yang, Shi-Kai Wang and Huan-Xin Chen Tags: Research Source Type: research
Randomized clinical trial of low dose suramin intravenous infusions for treatment of autism spectrum disorder
There is a critical need for effective treatment of the core symptoms of autism spectrum disorder (ASD). The purinergic antagonist suramin may improve core symptoms through restoration of normal mitochondrial ... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 6, 2023 Category: Psychiatry Authors: David Hough, Alice R. Mao, Michael Aman, Reymundo Lozano, Constance Smith-Hicks, Veronica Martinez-Cerdeno, Michael Derby, Zachary Rome, Niel Malan and Robert L. Findling Tags: Research Source Type: research
A shift in psychiatry through AI? Ethical challenges
The digital transformation has made its way into many areas of society, including medicine. While AI-based systems are widespread in medical disciplines, their use in psychiatry is progressing more slowly. How... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 2, 2023 Category: Psychiatry Authors: Saskia Wilhelmy, Giancarlo Giupponi, Dominik Gro ß, Klaus Eisendle and Andreas Conca Tags: Comment Source Type: research
Borderline personality disorder and early psychosis: a narrative review
The purpose of the present review was to summarize the main literature contribution on the relationship between borderline personality disorder (BPD) and early psychosis. While retracing the historical path of... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 2, 2023 Category: Psychiatry Authors: Arianna Biancalani, Lorenzo Pelizza and Marco Menchetti Tags: Review Source Type: research
Psychometric properties of the Clinical Assessment Interview for Negative Symptoms (CAINS) in patients with depression and its relationship to affective symptoms
There is a conceptual overlap between negative and depressive symptoms, requiring further exploration to advance the understanding of negative symptoms. The aim of this study was to examine psychometric proper... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - October 26, 2023 Category: Psychiatry Authors: Johan Bengtsson, Parya Rad, Martin Cernvall and Robert Bod én Tags: Research Source Type: research
Stress, depression, anxiety, and quality of life among the healthcare workers during COVID-19 pandemic in Syria: a multi-center study
The COVID-19 pandemic emerged as an expected source of stress and anxiety as the healthcare workers had to work for long hours in close contact with infected patients, thus increasing the probability of medica... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - October 16, 2023 Category: Psychiatry Authors: Hasan Nabil Al Houri, Abdullah Alhouri, Douaa Mohammad Nazir Arrouk, Ahmad Nabil Al Houri, Sami Jomaa, Alaa Sharabi, Hussein Kannout and Youssef Latifeh Tags: Research Source Type: research
DNMT1 SNPs (rs2114724 and rs2228611) associated with positive symptoms in Chinese patients with schizophrenia
Schizophrenia is a serious mental disorder with complex clinical manifestations, while its pathophysiological mechanism is not fully understood. Accumulated evidence suggested the alteration in epigenetic path... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - October 13, 2023 Category: Psychiatry Authors: Junjiao Ping, Jing Wan, Caiying Huang, Jinming Yu, Jiali Luo, Zhiqiang Xing, Xingguang Luo, Baoguo Du, Tingyun Jiang and Jie Zhang Tags: Research Source Type: research
Catatonia-like behavior and immune activation: a crosstalk between psychopathology and pathology in schizophrenia
In Kalhbaum's first characterization of catatonia, the emotional symptoms, such as decreased or restricted expression of feelings and emotions, which is described as blunted affect, are related to the motor sy... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - October 11, 2023 Category: Psychiatry Authors: Antonino Messina, Filippo Caraci, Eugenio Aguglia and Maria Salvina Signorelli Tags: Research Source Type: research
