Clarification of the molecular mechanisms underlying glyphosate-induced major depressive disorder: a network toxicology approach
Major depressive disorder (MDD) is predicted to become the second most common cause of disability in the near future. Exposure to glyphosate (Gly)-based herbicides has been linked to the onset of MDD. However,... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 31, 2024 Category: Psychiatry Authors: Jianan Li and Haoran Bi Tags: Research Source Type: research

Analyzing the psychometric properties of the PHQ-9 using item response theory in a Chinese adolescent population
People are more likely to fall victim to depression during adolescence since it is a period of rapid biopsychosocial transformation. Despite this, most depression research has concentrated on clinical issues, ... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 23, 2024 Category: Psychiatry Authors: Xuliang Gao and Ziyu Liu Tags: Research Source Type: research

On mental pain and suicide risk in modern psychiatry
Facing suicide risk is probably the most difficult task for clinicians when dealing with patients in crisis. It requires professional, intellectual, and emotional efforts. Suicide risk assessment can sometimes... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 16, 2024 Category: Psychiatry Authors: Maurizio Pompili Tags: Review Source Type: research

Predicting quetiapine dose in patients with depression using machine learning techniques based on real-world evidence
Being one of the most widespread, pervasive, and troublesome illnesses in the world, depression causes dysfunction in various spheres of individual and social life. Regrettably, despite obtaining evidence-base... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 6, 2024 Category: Psychiatry Authors: Yupei Hao, Jinyuan Zhang, Jing Yu, Ze Yu, Lin Yang, Xin Hao, Fei Gao and Chunhua Zhou Tags: Research Source Type: research

Diagnostic value and role of serum miR-15a-5p in patients with schizophrenia
The objective of this research was to explore the level of miR-15a-5p in patients with s... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 5, 2024 Category: Psychiatry Authors: Zhen Xu, Ruidong Yang, Guanwen Chen and Mingjun Jiang Tags: Research Source Type: research

Weight change following diagnosis with psychosis: a retrospective cohort study in Greater Manchester, UK
Weight gain in the months/years after diagnosis/treatment of severe enduring mental illness (SMI) is a major predictor of future diabetes, dysmetabolic profile and increased risk of cardiometabolic diseases. T... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 3, 2024 Category: Psychiatry Authors: Adrian Heald, Chris Daly, John Julian Warner-Levy, Richard Williams, Cheyenne Meehan, Mark Livingston, Toby Pillinger, Lamiece Hussain and Joseph Firth Tags: Research Source Type: research

Predictors of antipsychotics switching among ambulatory patients with schizophrenia in Ethiopia: a multicenter hospital-based cross-sectional study
This study aimed to assess the prevalence of antipsychotic medication switches and determinants amon... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 3, 2024 Category: Psychiatry Authors: Mekdes Kiflu, Telake Azale, Kale Gubae, Samuel Agegnew Wondm, Ephrem Mebratu, Asrat EliasErgena, Ousman Abubeker and Gizework Alemnew Mekonnen Tags: Research Source Type: research

Occurrences of post-traumatic stress disorder, anxiety, depression, and burnout syndrome in ICU staff workers after two-year of the COVID-19 pandemic: the international PSY-CO in ICU study
The present study aimed at assessing the prevalences of post-traumatic stress disorder (PTSD) (main objective), anxiety, depression, and burnout syndrome (BOS) and their associated factors in intensive care un... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - January 3, 2024 Category: Psychiatry Authors: Claire Roger, Lowel Ling, M élissa Petrier, Loubna Elotmani, Enora Atchade, Bernard Allaouchiche, Frédéric Aubrun, Jean-Michel Constantin, Claire Dahyot-Fizelier, Nathalie Delhaye, Hervé Dupont, Marc-Olivier Fischer, Marc Garnier, Etienne Gayat, Carol Tags: Research Source Type: research

Effect of perceived stigma on work and social roles among individuals with mental health disorders in Saudi Arabia: findings from a national survey
It is known worldwide that stigma towards mental illness exists. Studies on stigma perceived by patients with mental illness have shown decreased quality of life and a negative impact on work, school and socia... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 14, 2023 Category: Psychiatry Authors: Areej AlFattani, Lisa Bilal, Sami Y. Saad, Mohammad Talal Naseem, Sanaa Hyder, Abdulhamid Alhabib, Abdullah Alsubaie and Yasmin Altwaijri Tags: Research Source Type: research

Real-world predictors of divorce among outpatients with bipolar disorder: sex differences and clinical implications
Bipolar disorder is a mental illness characterized by recurring episodes of mania and depression and is known to cause social impairment. Additionally, it has been revealed that bipolar disorder increases the ... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 12, 2023 Category: Psychiatry Authors: Keita Tokumitsu, Norio Sugawara, Naoto Adachi, Yukihisa Kubota, Yoichiro Watanabe, Kazuhira Miki, Takaharu Azekawa, Koji Edagawa, Eiichi Katsumoto, Seiji Hongo, Eiichiro Goto, Hitoshi Ueda, Masaki Kato, Reiji Yoshimura, Atsuo Nakagawa, Toshiaki Kikuchi & Tags: Research Source Type: research

Sex difference in incidence of major depressive disorder: an analysis from the Global Burden of Disease Study 2019
This study was aimed to evaluate sex difference in global MDD incidence by year, age, and socioeconomic status, according... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 12, 2023 Category: Psychiatry Authors: Sangzi Li, Xuan Zhang, Yilu Cai, Leilei Zheng, Hu Pang and Lixia Lou Tags: Research Source Type: research

Facts and myths about the use of lithium for bipolar disorder in routine clinical practice: an expert consensus paper
Bipolar disorder is one of the most burdensome severe mental disorders, characterized by high levels of personal and social disability. Patients often need an integrated pharmacological and non-pharmacological... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 6, 2023 Category: Psychiatry Authors: Andrea Fiorillo, Gaia Sampogna, Umberto Albert, Giuseppe Maina, Giulio Perugi, Maurizio Pompili, Gianluca Rosso, Gabriele Sani and Alfonso Tortorella Tags: Review Source Type: research

Clinical characteristics of suicidal behavior in first hospitalization and drug-na ïve patients with major depressive disorder
Major depressive disorder (MDD) is a major and common cause of suicide. The purpose of this article is to report the clinical characteristics and patterns of co-morbid suicidal behavior (SB) in first hospitali... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - December 6, 2023 Category: Psychiatry Authors: Xianzhi Sun, Lili Yin, Yingying Zhang, Xuebing Liu and Jun Ma Tags: Research Source Type: research

Discontinuation of antidepressant treatment: a retrospective cohort study on more than 20,000 participants
Factors influencing antidepressant treatment discontinuation are poorly understood. In the present study, we aimed to estimate the prevalence of antidepressant treatment discontinuation and identify demographi... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 24, 2023 Category: Psychiatry Authors: Luis M. Garcia-Marin, Aoibhe Mulcahy, Enda M. Byrne, Sarah E. Medland, Naomi R. Wray, Freddy Chafota, Penelope A. Lind, Nicholas G. Martin, Ian B. Hickie, Miguel E. Renter ía and Adrian I. Campos Tags: Research Source Type: research

Mendelian randomization studies of depression: evidence, opportunities, and challenges
Major depressive disorder (MDD) poses a significant social and economic burden worldwide. Identifying exposures, risk factors, and biological mechanisms that are causally connected to MDD can help build a scie... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - November 23, 2023 Category: Psychiatry Authors: Wang-ran Ma, Lei-lei Zhang, Jing-ying Ma, Fang Yu, Ya-qing Hou, Xiang-rui Feng and Lin Yang Tags: Review Source Type: research