Annals of Clinical and Laboratory Science This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The Role and Mechanism of STIM1/Orai1-Regulated Ca 2+ Influx in Myocardial Hypertrophy in Type 2 Diabetes Mellitus
CONCLUSION: STIM1/Orai1-mediated SOCE regulates p-CaMKII levels, thereby inducing myocardial hypertrophy in T2DM.PMID:38514055 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Sisi Zhang Wenping Zang Source Type: research

Annals of Clinical and Laboratory Science: Information for Authors
Ann Clin Lab Sci. 2024 Jan;54(1):131-132.NO ABSTRACTPMID:38514056 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Source Type: research

Elevated MMP1 Expression in Carcinoma-Associated Fibroblasts of Breast Cancer Contributes to Tumor Progression and Unfavorable Prognosis
CONCLUSION: The results indicated that MMP1 expression in CAFs may participate in the malignant phenotype and unfavorable prognosis of breast cancer.PMID:38514057 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Chunfang Xi Zhendi Song Qingyu Cui Ye Zhao Kaifu Li Hua Kang Source Type: research

Role of NF- κB p65/TNF-α in Cell Apoptosis in the Fetal Membranes of Pregnant Women with Preterm Premature Rupture of Membranes
CONCLUSION: NF-[Formula: see text]B p65 is involved in the occurrence of PPROM by promoting the expression of TNF-α, which upregulates caspase-3 to cause apoptosis of fetal membrane cells.PMID:38514058 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Shi-Huan Tang Xian Tang Ling Liu Lu Peng Hong-Mei Zhang Hui Zhang Ting Long Pei-Ling Wu Xian-Ping Zhang Source Type: research

Rapid and Reliable HLA-B*59:01 Genotyping to Prevent Carbonic Anhydrase Inhibitor-Induced Severe Cutaneous Adverse Reactions
CONCLUSION: Duplex allele-specific PCR is a rapid, reliable, and economical assay for screening the HLA-B*59:01 allele.PMID:38514059 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Ji Young Huh Yong Ju Song Geon Park Source Type: research

Shenmai Injection Alleviates Myocardial Ferroptosis via Activating the AKT1/mTOR Pathway in Rats with Acute Myocardial Infarction
CONCLUSION: This study revealed that SMI exerts a protective effect against myocardial injury and ferroptosis caused by AMI via the activation of the AKT1/mTOR pathway.PMID:38514060 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Ming Lu Yeying Zhang Xuhui Ma Mingqiu Cen Shidong Lin Xiaolu Qian Jia Yu Xiaoying Huang Zhuxiu Jiang Source Type: research

Idiopathic Hypereosinophilic Syndrome in a Professional Athlete
CONCLUSION: Findings endorse the diagnosis of HES. HES is a rare condition that is difficult to diagnose. Early clinical diagnostic signs of HES may include fatigue, cough, breathlessness, and fever.PMID:38514061 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Sarah Shidid Pakinam Mekki Tamar A Smith-Norowitz Source Type: research

 Technical Note: Comparison of Alinity c Hemoglobin A1c Immunoassay with Premier Hb9210 Automated HPLC Assay: A Preliminary Report
CONCLUSIONS: We conclude that HbA1c assay on the Alinity c analyzer is a viable alternative to HPLC for measuring HbA1c in clinical laboratories but values at the decision points must be interpreted with caution and if necessary should be repeated by a reference HPLC method.PMID:38514062 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Ashton Walton Jonathan Meador Kelsey Woodard Sean Tucker Susan McIntyre Amitava Dasgupta Source Type: research

Dexmedetomidine Alleviates Propofol Infusion Syndrome-Induced Myocardial Injury through Inhibiting Ferroptosis Associated with Accumulation of Reactive Oxygen Species
CONCLUSIONS: Dex could alleviate PRIS-induced myocardial injury by inhibiting ferroptosis associated with accumulation of ROS. Combined sedation using propofol and Dex might be a potential strategy for the prevention and treatment of PRIS-induced cardiotoxicity.PMID:38514063 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Jinhui Sun Bing Zhang Qiang Geng Jiayinati Halimujiang Chang Song Min Xi Ting Wang Source Type: research

Predictive and Carcinogenic Roles of Necroptosis-Related miR-425-5p and miR-16-5p in Esophageal Squamous Cell Carcinoma
CONCLUSION: The pro-carcinogenic role of miR-425-5p and miR-16-5p has been observed in esophageal squamous cell carcinoma.PMID:38514064 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Xue Zhidan Xi Kedi Xi Dan Song Xing Sun Rui Source Type: research

Upregulation of miR-499a Targets Beclin1 to Modulate Astrocyte Autophagy and Promote Ischemic Stroke
CONCLUSION: Serum miR-499a in stroke patients may serve as a potential diagnostic indicator. MiR-499a-mediated inhibition of Beclin 1, subsequently leading to suppression of astrocytic autophagy and viability, may represent a pivotal mechanism underlying its promotion of IS.PMID:38514065 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Guanxiu Xian Daihong Song Ying Wei Fugao Huang Hongcheng Luo Source Type: research

Combined Use of Helicobacter pylori Genotyping and CDX2 Expression as a Predictor of Malignant Potential in Gastric Intestinal Metaplasia
CONCLUSION: These GIM subtypes (cagA+ vacAs1m1 H. pylori-positive GIM with negative CDX2 expression) resemble GC and should be evaluated similar to cancerous GIM.PMID:38514066 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Mengyuan Zhang Zhong Zhang Lanlan Jiao Li Liang Wei Bo Min Zhang Xiaobo Li Xingwei Fu Xuguang Wang Source Type: research

A Rare Autopsy Case of Aggressive Combined Hepatocellular-Cholangiocarcinoma in 59-Year-Old Female
Ann Clin Lab Sci. 2024 Jan;54(1):106-111.ABSTRACTCombined hepatocellular-cholangiocarcinoma (cHCC-CC) is a liver tumor with features of both hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). It consists of intermingled malignant biliary and hepatic tissue and thus a distinct entity, rather than two separate coexisting malignancies. A 59-year-old female with a history of hepatitis C and cirrhosis presented with abdominal pain and altered mental status. She developed hematemesis, and despite extensive interventions, she expired one day after her initial presentation. At autopsy, the liver was diffusel...
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Ahmed A Ahmed Brandon Gehris Michelle McDonald Suhair Al Salihi L Maximilian Buja Source Type: research

HNRNPC Regulates GLUT1/LDHA Pathway by Stabilizing FOXM1 mRNA to Promote the Progression and Aerobic Glycolysis of Multiple Myeloma
CONCLUSION: HNRNPC regulated GLUT1/LDHA pathway by stabilizing FOXM1 mRNA to promote the progression and aerobic glycolysis of MM.PMID:38514068 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Ningning Wu Yao Zhu Source Type: research

The Monocyte-to-Lymphocyte Ratio on the 6 th Day Postburn Is Associated with Clinical Outcome of Severe Burns
CONCLUSIONS: Our results revealed the dynamic characteristics of the MLR value in the early stage of severe burns, reflecting important changes in the immune/inflammatory related stress response soon after injury, low MLR level was associated with the worsening of disease condition.PMID:38514069 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - March 21, 2024 Category: Laboratory Medicine Authors: Lizhu Zhi Yilan Xia Fang Jin Xiaojie He Xingang Wang Xuanliang Pan Source Type: research