Ventilation and Complications after Lung Resection: Comment
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Saving Grace: What Patients Teach Doctors about Life, Death, and the Balance in Between
By David D.Alfery, M.D. Eugene, Oregon, Resource Publications, 2023. Pages: 149. Price: $21.00. (Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Phosphorylated Upstream Frameshift 1 –dependent Nonsense-mediated μ-Opioid Receptor mRNA Decay in the Spinal Cord Contributes to the Development of Neuropathic Allodynia–like Behavior in Rats
ConclusionsThis study suggests that phosphorylated UPF1 –dependent nonsense-mediated μ-opioid receptor mRNA decay is involved in the pathogenesis of neuropathic pain.Editor ’s PerspectiveWhat We Already Know about This TopicMaladaptive neuroplasticity in the spinal cord contributes to the development of allodyniaNonsense-mediated messenger RNA (mRNA) decay regulates protein expression and plays an important role in synaptic plasticityThe role of nonsense-mediated mRNA decay in the development of allodynia is incompletely understoodWhat This Article Tells Us That Is NewIn adult rats, spinal nerve ligation triggered the...
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Antiemetic Administration and Its Association with Race: A Retrospective Cohort Study
ConclusionsIn a perioperative registry data set, Blackversus White patient race was associated with less antiemetic administration, after controlling for all accepted postoperative nausea and vomiting risk factors.Editor ’s PerspectiveWhat We Already Know about This TopicSocial determinants, such as race, may lead to disparities in health carePerioperative antiemetic administration has been found to differ with socioeconomic statusWhat This Article Tells Us That Is NewUsing data from the Multicenter Perioperative Outcomes Group registry and adjusting for Apfel postoperative nausea and vomiting risk factors, Blackversus W...
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

And Finally: Matters of Life and Death
By HenryMarsh, C.B.E., F.R.C.S., New York, St. Martin ’s Press, 2023 (Hardcover). Pages: 227. ISBN-13: 978-1-250-28608-6 (Hardcover). ISBN-13: 978-1-787-33114-3 (Trade paperback). ISBN-13: 978-1-250-28609-3 (ebook). Price: $27.99 (Hardcover). Price: $17.33 (Softcover). Price: $11.49 (ebook). (Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Prone Positioning in COVID-19 ARDS: Reply
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Prone Positioning in COVID-19 ARDS: Comment
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Deep Isoflurane Anesthesia Is Associated with Alterations in Ion Homeostasis and Specific Na + /K + -ATPase Impairment in the Rat Brain
ConclusionsThe results demonstrate cortical ion homeostasis perturbation and specific Na+/K+-ATPase impairment during deep isoflurane anesthesia. Slowed potassium clearance and extracellular accumulation might modulate cortical excitability during burst suppression generation, while prolonged Na+/K+-ATPase impairment could contribute to neuronal dysfunction after deep anesthesia.Editor ’s PerspectiveWhat We Already Know about This TopicChanges in extracellular ion composition modulate neuronal network activityThe sodium/potassium-adenosine triphosphatase (Na+/K+-ATPase) enzyme plays an essential role in the maintenance o...
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Motor Vehicle Crash Risk among Adults Undergoing General Surgery: A Retrospective Case-crossover Study
ConclusionsUsing population-based crash and hospital discharge data, the incidence of motor vehicle crashes over a 28-day period did not change on average before compared to after surgery. The authors provide data on crash risk after surgery and highlight specific populations at risk.Editor ’s PerspectiveWhat We Already Know about This TopicThere are limited data to guide return to driving recommendations for patients undergoing surgeryIt remains unclear whether patients have an increased risk of motor vehicle crashes in the first few weeks after surgery compared to before surgeryWhat This Article Tells Us That Is NewIn ...
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Perineural and Systemic Dexamethasone and Ulnar Nerve Block Duration: A Randomized, Blinded, Placebo-controlled Trial in Healthy Volunteers
ConclusionsPerineural dexamethasone as an adjunct to bupivacaine in healthy volunteers resulted in a greater duration of an ulnar nerve block when compared with placebo. Systemic dexamethasone resulted in a similar duration as placebo.Editor ’s PerspectiveWhat We Already Know about This TopicPerineural dexamethasone may prolong the duration of postoperative analgesia afforded by a regional anestheticOther studies have suggested that intravenous dexamethasone has analgesic properties that could contribute to regional anesthetic durationWhat This Article Tells Us That Is NewWhen carefully controlling for the effects of sys...
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Is Continuous Intraoperative Monitoring of Mean Arterial Pressure as Good as the Hypotension Prediction Index Algorithm?: Research Letter
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Cohabitation of Neonatally Sevoflurane-exposed and -unexposed Male Rats Affects Their Respective Behavioral Phenotypes: Research Letter
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

A Chest Tube Inadvertently Inserted into Tracheal Lumen
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Anesthesiology
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research

Instructions for Obtaining A nesthesiology Continuing Medical Education (CME) Credit
(Source: Anesthesiology)
Source: Anesthesiology - May 19, 2023 Category: Anesthesiology Source Type: research