Smart Glasses for Radial Arterial Catheterization in Pediatric Patients: A Randomized Clinical Trial
ConclusionsSmart glasses-assisted ultrasound-guided radial artery catheterization improved the first-attempt success rate and ergonomic satisfaction while reducing the first-attempt procedure time and overall complication rates in small pediatric patients.Editor ’s PerspectiveWhat We Already Know about This TopicAlthough ultrasound is becoming commonplace to guide arterial cannulation in children, there is still an appreciable failure to succeed on the first passHead-mounted displays are a new technology finding novel applications in medical practiceWhat This Article Tells Us That Is NewIn a randomized controlled trial c...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research

Dose-dependent Respiratory Depression by Remifentanil in the Rabbit Parabrachial Nucleus/K ölliker–Fuse Complex and Pre-Bötzinger Complex
ConclusionsOpioid reversal in the parabrachial nucleus/K ölliker–Fuse complexplus pre-B ötzinger complex only partially reversed respiratory depression from analgesic and even less from “apneic” opioid doses. The lack of recovery pointed to opioid-induced depression of respiratory drive that determines the activity of these areas.Editor ’s PerspectiveWhat We Already Know about This TopicOpioid-sensitive inputs to respiratory rate and rhythm originate in the pre-B ötzinger complex, the parabrachial nucleus, and the Kölliker–Fuse nucleusWhat This Article Tells Us That Is NewThe hypothesis that opioid-induced re...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research

Personal Protective Equipment: Reply
(Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research

Reversing Rivaroxaban Anticoagulation as Part of a Multimodal Hemostatic Intervention in a Polytrauma Animal Model
ConclusionsProthrombin complex concentrate effectively reduced blood loss, restored hemostasis, and balanced thrombin generation. A multimodal hemostatic approach using tranexamic acid plus fibrinogen concentrate enhanced the effect of low doses of prothrombin complex concentrate, potentially reducing the prothrombin complex concentrate doses required for effective bleeding control.Editor ’s PerspectiveWhat We Already Know about This TopicSignificant bleeding can occur after trauma, especially with preexisting anticoagulation. Despite multiple therapeutic approaches, optimal management remains to be determined.What This ...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research

Opioid-free Anesthesia: Comment
(Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research