Skirting Male Chauvinism in Physician Training: Dr. Emily Blackwell and the Woman ’s Medical College
After overcoming great obstacles, Emily Blackwell, M.D. (1826 to 1910), the brilliant and bold younger sister of Elizabeth Blackwell, M.D., became the third woman to earn her medical degree in the United States. A month after her graduation in 1854, she boarded a transatlantic steamship to seek a training opportunity with Professor James Y. Simpson, renowned pioneer of chloroform anesthesia and Chair of Midwifery at the University of Edinburgh. To Emily ’s relief, Simpson welcomed her warmly and offered to help her achieve her goals. She marveled at his diagnostic acumen and skill with chloroform administration. However,...
Source: Anesthesiology - October 13, 2021 Category: Anesthesiology Source Type: research
The National Halothane Study: Did “Fluothane” Deliver or De-liver?
One fateful morning in 1962, a community hospital pathologist telephoned John Bunker, M.D., Chair of Anesthesia at Stanford. A 16-year-old girl had died of liver failure two weeks after receiving halothane (branded “Fluothane,”left) anesthesia for a wrist-laceration repair. Her case, along with others, sparked the National Halothane Study (right), a large-scale comparison of halothane with other anesthetics in relation to the incidence of fatal hepatic necrosis. Within the first month, randomization was halted on ethical grounds following a new case of lethal hepatitis. In the end, a retrospective cohort design found 8...
Source: Anesthesiology - October 13, 2021 Category: Anesthesiology Source Type: research
This Month in Anesthesiology
(Source: Anesthesiology)
Source: Anesthesiology - October 13, 2021 Category: Anesthesiology Source Type: research
Science, Medicine, and the Anesthesiologist
Key Papers from the Most Recent Literature Relevant to Anesthesiologists (Source: Anesthesiology)
Source: Anesthesiology - October 13, 2021 Category: Anesthesiology Source Type: research
Vasopressor Showdown: Phenylephrine vs. Ephedrine
Complex Information for Anesthesiologists Presented Quickly and Clearly (Source: Anesthesiology)
Source: Anesthesiology - October 13, 2021 Category: Anesthesiology Source Type: research
A Roadmap for Environmental Sustainability of Plastic Use in Anesthesia and the Perioperative Arena
The authors provide an overview of the common plastics generated in the perioperative setting and outline practical recommendations that can help achieve a circular economy and lessen the impact of plastic waste on the environment. (Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Perioperative Stroke: Comment
(Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
The Quality Improvement Challenge: A Practical Guide for Clinicians
By BanchsRichard J., M.D., and PopMichael R., S.S.M.B., M.B.A. London, Wiley Blackwell, 2021. Pages: 474. ISBN-13: 9781119698982. ISBN-10: 9781119699019. Price: $59.99. (Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Liposomal Bupivacaine to Treat Postoperative Pain: Comment
(Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Perioperative Normal Saline Administration and Delayed Graft Function in Patients Undergoing Kidney Transplantation: A Retrospective Cohort Study
ConclusionsHigh percent normal saline administration is associated with delayed graft function in kidney transplant recipients.Editor ’s PerspectiveWhat We Already Know about This TopicRandomized controlled trials of balanced crystalloidsversus normal saline have not demonstrated superiority of either strategy in the generalized surgical populationPatients undergoing kidney transplantation and receiving normal saline experience the metabolic complications of hyperchloremiaThe association of normal saline administration with delayed graft function, defined as renal replacement therapy within 1 week of transplant, is uncle...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Avatar Models and Radar Plots: The Future of Intraoperative Anesthesia Monitoring
(Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Excitation of Putative Glutamatergic Neurons in the Rat Parabrachial Nucleus Region Reduces Delta Power during Dexmedetomidine but not Ketamine Anesthesia
ConclusionsThese results suggest that the effectiveness of parabrachial nucleus excitation to change the neurophysiologic and behavioral effects of anesthesia depends on the anesthetic ’s molecular target.Editor ’s PerspectiveWhat We Already Know about This TopicThe parabrachial nucleus is an arousal area in the brainstem primarily composed of excitatory glutamatergic neuronsStimulation of the parabrachial nucleus reduces cortical delta oscillation power and promotes arousal during or after administration of anesthetics targeting principally the γ-aminobutyric acid type A receptorThe effects of parabrachial nucleus st...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Ipsilateral and Simultaneous Comparison of Responses from Acceleromyography- and Electromyography-based Neuromuscular Monitors
ConclusionsBias was lower than in previous studies. Limits of agreement were wider than expected because acceleromyography readings varied more than EMG both at baseline and during recovery. The EMG-based monitor had higher precision and greater repeatability than acceleromyography. This difference between monitors was even greater when EMG data were compared to raw (nonnormalized) acceleromyography measurements. The EMG monitor is a better indicator of adequate recovery from neuromuscular block and readiness for safe tracheal extubation than the acceleromyography monitor.Editor ’s PerspectiveWhat We Already Know about T...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Anesthesia Method, Tourniquet Use, and Persistent Postsurgical Pain after Total Knee Arthroplasty: A Prespecified Secondary Analysis of a Randomized Trial
ConclusionsThe type of anesthesia (spinalvs. general) or tourniquet use has no clinically important effect on persistent postsurgical pain after total knee arthroplasty.Editor ’s PerspectiveWhat We Already Know about This TopicPersistent pain after total knee arthroplasty is common and adversely affects outcomesThe choice of anesthesia and use of a tourniquet during knee arthroplasty may have an impact on complication rates, but the effects on persistent pain are poorly knownWhat This Article Tells Us That Is NewIn a secondary analysis of a study involving 404 patients, no clinically important differences in pain scores ...
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
Personal Protective Equipment: Comment
(Source: Anesthesiology)
Source: Anesthesiology - September 15, 2021 Category: Anesthesiology Source Type: research
