Type IV pili facilitated natural competence in Fusobacterium nucleatum
CONCLUSIONS: In summary, this proof of principle study provides the first characterization of natural competence in Fusobacterium nucleatum and highlights the potential to exploit this DNA import mechanism as a genetic tool to characterize virulence mechanisms of an opportunistic oral pathogen.PMID:37451427 | DOI:10.1016/j.anaerobe.2023.102760 (Source: Anaerobe)
Source: Anaerobe - July 14, 2023 Category: Microbiology Authors: Blake E Sanders Ariana Umana Tam T D Nguyen Kevin J Williams Christopher C Yoo Michael A Casasanta Bryce Wozniak Daniel J Slade Source Type: research
Antimicrobial susceptibility of Bacteroides fragilis group organisms in Hong Kong, 2020-2021
CONCLUSIONS: The data demonstrated emerging BFG resistance to several important anti-anaerobic antibiotics and highlights the importance of anaerobic susceptibility testing in clinical laboratories to guide therapy.PMID:37429411 | DOI:10.1016/j.anaerobe.2023.102756 (Source: Anaerobe)
Source: Anaerobe - July 10, 2023 Category: Microbiology Authors: Hanshu Fang Xin Li Mei-Kum Yan Man-Ki Tong Kin-Hung Chow Vincent Chi-Chung Cheng Pak-Leung Ho Source Type: research
Antimicrobial susceptibility of Bacteroides fragilis group organisms in Hong Kong, 2020-2021
CONCLUSIONS: The data demonstrated emerging BFG resistance to several important anti-anaerobic antibiotics and highlights the importance of anaerobic susceptibility testing in clinical laboratories to guide therapy.PMID:37429411 | DOI:10.1016/j.anaerobe.2023.102756 (Source: Anaerobe)
Source: Anaerobe - July 10, 2023 Category: Microbiology Authors: Hanshu Fang Xin Li Mei-Kum Yan Man-Ki Tong Kin-Hung Chow Vincent Chi-Chung Cheng Pak-Leung Ho Source Type: research
Antimicrobial susceptibility of Bacteroides fragilis group organisms in Hong Kong, 2020-2021
CONCLUSIONS: The data demonstrated emerging BFG resistance to several important anti-anaerobic antibiotics and highlights the importance of anaerobic susceptibility testing in clinical laboratories to guide therapy.PMID:37429411 | DOI:10.1016/j.anaerobe.2023.102756 (Source: Anaerobe)
Source: Anaerobe - July 10, 2023 Category: Microbiology Authors: Hanshu Fang Xin Li Mei-Kum Yan Man-Ki Tong Kin-Hung Chow Vincent Chi-Chung Cheng Pak-Leung Ho Source Type: research
Antimicrobial susceptibility of Bacteroides fragilis group organisms in Hong Kong, 2020-2021
CONCLUSIONS: The data demonstrated emerging BFG resistance to several important anti-anaerobic antibiotics and highlights the importance of anaerobic susceptibility testing in clinical laboratories to guide therapy.PMID:37429411 | DOI:10.1016/j.anaerobe.2023.102756 (Source: Anaerobe)
Source: Anaerobe - July 10, 2023 Category: Microbiology Authors: Hanshu Fang Xin Li Mei-Kum Yan Man-Ki Tong Kin-Hung Chow Vincent Chi-Chung Cheng Pak-Leung Ho Source Type: research
Strain specificity in fusobacterial co-aggregation with colorectal cancer-relevant species
CONCLUSIONS: Co-aggregation interactions suggest the ability to encourage the formation of biofilms, and colonic biofilms, in turn, have been linked to promotion and/or progression of CRC. Co-aggregation between F. nucleatum subsp. Animalis and CRC-linked species such as C. concisus, Gemella spp., H. hathewayi, and P. micra may contribute to both biofilm formation along CRC lesions and to disease progression.PMID:37423597 | DOI:10.1016/j.anaerobe.2023.102758 (Source: Anaerobe)
Source: Anaerobe - July 9, 2023 Category: Microbiology Authors: Avery V Robinson Emma Allen-Vercoe Source Type: research
Strain specificity in fusobacterial co-aggregation with colorectal cancer-relevant species
CONCLUSIONS: Co-aggregation interactions suggest the ability to encourage the formation of biofilms, and colonic biofilms, in turn, have been linked to promotion and/or progression of CRC. Co-aggregation between F. nucleatum subsp. Animalis and CRC-linked species such as C. concisus, Gemella spp., H. hathewayi, and P. micra may contribute to both biofilm formation along CRC lesions and to disease progression.PMID:37423597 | DOI:10.1016/j.anaerobe.2023.102758 (Source: Anaerobe)
Source: Anaerobe - July 9, 2023 Category: Microbiology Authors: Avery V Robinson Emma Allen-Vercoe Source Type: research
Description of eight human infections caused by Bacteroides pyogenes in a tertiary hospital of northern Spain
Anaerobe. 2023 Jul 5:102759. doi: 10.1016/j.anaerobe.2023.102759. Online ahead of print.ABSTRACTBacteroides pyogenes is a Gram-negative obligate anaerobe, saccharolytic, non-motile, non-pigment-producing and non-spore-forming rod. Reports of human infections caused by B. pyogenes are scarce, with approximately 30 cases documented in scientific literature. The aim of this study was to describe the clinical characteristics of 8 different patients and to study the in vitro antibiotic susceptibility of the strains, as well as to evaluate the in vivo activity of the prescribed treatments. We conducted a descriptive retrospectiv...
Source: Anaerobe - July 7, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mikel Joseba Urrutikoetxea Guti érrez Mary Paz Roche Matheus Itziar Angulo L ópez Cristina Aspichueta Vivanco Felicitas Elena Calvo Muro Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Description of eight human infections caused by Bacteroides pyogenes in a tertiary hospital of northern Spain
Anaerobe. 2023 Jul 5:102759. doi: 10.1016/j.anaerobe.2023.102759. Online ahead of print.ABSTRACTBacteroides pyogenes is a Gram-negative obligate anaerobe, saccharolytic, non-motile, non-pigment-producing and non-spore-forming rod. Reports of human infections caused by B. pyogenes are scarce, with approximately 30 cases documented in scientific literature. The aim of this study was to describe the clinical characteristics of 8 different patients and to study the in vitro antibiotic susceptibility of the strains, as well as to evaluate the in vivo activity of the prescribed treatments. We conducted a descriptive retrospectiv...
Source: Anaerobe - July 7, 2023 Category: Microbiology Authors: Domingo Fern ández Vecilla Mikel Joseba Urrutikoetxea Guti érrez Mary Paz Roche Matheus Itziar Angulo L ópez Cristina Aspichueta Vivanco Felicitas Elena Calvo Muro Jos é Luis Díaz de Tuesta Del Arco Source Type: research
Clostridioides difficile PCR Tcdb Cycle Threshold predicts toxin EIA positivity but not severity of infection
CONCLUSION: CT value was an acceptable predictor for EIA toxin but less so for clinical severity. Our study potentially supports a diagnostic algorithm including CT value to reduce the number of EIA toxin assays performed.PMID:37406762 | DOI:10.1016/j.anaerobe.2023.102755 (Source: Anaerobe)
Source: Anaerobe - July 5, 2023 Category: Microbiology Authors: Regan Mah Kerstin Locher Theodore S Steiner Aleksandra Stefanovic Source Type: research
Clostridioides difficile PCR Tcdb Cycle Threshold predicts toxin EIA positivity but not severity of infection
CONCLUSION: CT value was an acceptable predictor for EIA toxin but less so for clinical severity. Our study potentially supports a diagnostic algorithm including CT value to reduce the number of EIA toxin assays performed.PMID:37406762 | DOI:10.1016/j.anaerobe.2023.102755 (Source: Anaerobe)
Source: Anaerobe - July 5, 2023 Category: Microbiology Authors: Regan Mah Kerstin Locher Theodore S Steiner Aleksandra Stefanovic Source Type: research
Clostridioides difficile PCR Tcdb Cycle Threshold predicts toxin EIA positivity but not severity of infection
CONCLUSION: CT value was an acceptable predictor for EIA toxin but less so for clinical severity. Our study potentially supports a diagnostic algorithm including CT value to reduce the number of EIA toxin assays performed.PMID:37406762 | DOI:10.1016/j.anaerobe.2023.102755 (Source: Anaerobe)
Source: Anaerobe - July 5, 2023 Category: Microbiology Authors: Regan Mah Kerstin Locher Theodore S Steiner Aleksandra Stefanovic Source Type: research
Comparison of microbiological profile of enterotoxigenic Bacteroides fragilis (ETBF) isolates from subjects with colorectal cancer (CRC) or intestinal pre-cancerous lesions versus healthy individuals and evaluation of environmental factors involved in intestinal dysbiosis
CONCLUSIONS: Our data suggest that some types of ETBF seem to better adapt and colonize the human gut and that the selective pressure exerted by factors related to lifestyle, such as pharmacological therapy and weight, could facilitate their persistence in the gut and their possible involvement in CRC development.PMID:37380012 | DOI:10.1016/j.anaerobe.2023.102757 (Source: Anaerobe)
Source: Anaerobe - June 28, 2023 Category: Microbiology Authors: Patrizia Spigaglia Fabrizio Barbanti Elena Angela Pia Germinario Enrico Maria Criscuolo Giovanni Bruno Lupe Sanchez-Mete Barbara Porowska Vittoria Stigliano Fabio Accarpio Andrea Oddi Ilaria Zingale Silvia Rossi Roberta De Angelis Alessia Fabbri Source Type: research
Comparison of microbiological profile of enterotoxigenic Bacteroides fragilis (ETBF) isolates from subjects with colorectal cancer (CRC) or intestinal pre-cancerous lesions versus healthy individuals and evaluation of environmental factors involved in intestinal dysbiosis
CONCLUSIONS: Our data suggest that some types of ETBF seem to better adapt and colonize the human gut and that the selective pressure exerted by factors related to lifestyle, such as pharmacological therapy and weight, could facilitate their persistence in the gut and their possible involvement in CRC development.PMID:37380012 | DOI:10.1016/j.anaerobe.2023.102757 (Source: Anaerobe)
Source: Anaerobe - June 28, 2023 Category: Microbiology Authors: Patrizia Spigaglia Fabrizio Barbanti Elena Angela Pia Germinario Enrico Maria Criscuolo Giovanni Bruno Lupe Sanchez-Mete Barbara Porowska Vittoria Stigliano Fabio Accarpio Andrea Oddi Ilaria Zingale Silvia Rossi Roberta De Angelis Alessia Fabbri Source Type: research
Comparison of microbiological profile of enterotoxigenic Bacteroides fragilis (ETBF) isolates from subjects with colorectal cancer (CRC) or intestinal pre-cancerous lesions versus healthy individuals and evaluation of environmental factors involved in intestinal dysbiosis
CONCLUSIONS: Our data suggest that some types of ETBF seem to better adapt and colonize the human gut and that the selective pressure exerted by factors related to lifestyle, such as pharmacological therapy and weight, could facilitate their persistence in the gut and their possible involvement in CRC development.PMID:37380012 | DOI:10.1016/j.anaerobe.2023.102757 (Source: Anaerobe)
Source: Anaerobe - June 28, 2023 Category: Microbiology Authors: Patrizia Spigaglia Fabrizio Barbanti Elena Angela Pia Germinario Enrico Maria Criscuolo Giovanni Bruno Lupe Sanchez-Mete Barbara Porowska Vittoria Stigliano Fabio Accarpio Andrea Oddi Ilaria Zingale Silvia Rossi Roberta De Angelis Alessia Fabbri Source Type: research
