Probabilistic Prediction of Laboratory Test Information Yield
In this study, we assess whether stability in repeated laboratory diagnostic measurements is predictable with uncertainty estimates using electronic health record data available before the diagnostic is ordered. We use probabilistic regression to predict a distribution of plausible values, allowing use-time customization for various definitions of "stability" given dynamic ranges and clinical scenarios. After converting distributions into "stability" scores, the models achieve a sensitivity of 29% for white blood cells, 60% for hemoglobin, 100% for platelets, 54% for potassium, 99% for albumin and 35% for creatinine for pr...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Yixing Jiang Andrew H Lee Xiaoyuan Ni Conor K Corbin Jeremy A Irvin Andrew Y Ng Jonathan H Chen Source Type: research

Leveraging Unlabeled Clinical Data to Boost Performance of Risk Stratification Models for Suspected Acute Coronary Syndrome
AMIA Annu Symp Proc. 2024 Jan 11;2023:744-753. eCollection 2023.ABSTRACTThe performance of deep learning models in the health domain is desperately limited by the scarcity of labeled data, especially for specific clinical-domain tasks. Conversely, there are vastly available clinical unlabeled data waiting to be exploited to improve deep learning models where their training labeled data are limited. This paper investigates the use of task-specific unlabeled data to boost the performance of classification models for the risk stratification of suspected acute coronary syndrome. By leveraging large numbers of unlabeled clinica...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Yutong Wu David Conlan Siegfried Perez Anthony Nguyen Source Type: research

Digital Solutions Observed in Clinical Trials: A Formative Feasibility Scoping Review
AMIA Annu Symp Proc. 2024 Jan 11;2023:987-996. eCollection 2023.ABSTRACTGrowing digital access accelerates digital transformation of clinical trials where digital solutions (DSs) are increasingly and widely leveraged for improving trial efficiency, effectiveness, and accessibility. Many factors impact DS success including technology barriers, privacy concerns, or user engagement activities. It is unclear how those factors are considered or reported in the literature. Here, we perform a formative feasibility scoping review to identify gaps impacting DS quality and reproducibility in trials. Articles containing digital terms...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Taylor M Harrison Sungrim Moon Liwei Wang Sunyang Fu Hongfang Liu Source Type: research

Bridging the Skills Gap: Evaluating an AI-Assisted Provider Platform to Support Care Providers with Empathetic Delivery of Protocolized Therapy
AMIA Annu Symp Proc. 2024 Jan 11;2023:436-445. eCollection 2023.ABSTRACTDespite the high prevalence and burden of mental health conditions, there is a global shortage of mental health providers. Artificial Intelligence (AI) methods have been proposed as a way to address this shortage, by supporting providers with less extensive training as they deliver care. To this end, we developed the AI-Assisted Provider Platform (A2P2), a text-based virtual therapy interface that includes a response suggestion feature, which supports providers in delivering protocolized therapies empathetically. We studied providers with and without e...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: William R Kearns Jessica Bertram Myra Divina Lauren Kemp Yinzhou Wang Alex Marin Trevor Cohen Weichao Yuwen Source Type: research

Assessing Telemedicine Competencies: Developing and Validating Learner Measures for Simulation-Based Telemedicine Training
AMIA Annu Symp Proc. 2024 Jan 11;2023:474-483. eCollection 2023.ABSTRACTIn 2021, the Association of American Medical Colleges published Telehealth Competencies Across the Learning Continuum, a roadmap for designing telemedicine curricula and evaluating learners. While this document advances educators' shared understanding of telemedicine's core content and performance expectations, it does not include turn-key-ready evaluation instruments. At the University of Oklahoma School of Community Medicine, we developed a year-long telemedicine curriculum for third-year medical and second-year physician assistant students. We used ...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Blake Lesselroth Helen Monkman Ryan Palmer Craig Kuziemsky Andrew Liew Kristin Foulks Deirdra Kelly Ainsly Wolfinbarger Frances Wen Liz Kollaja Shannon Ijams Juell Homco Source Type: research

Development and Usability Testing of an Exercise-Based Primary Care Fall Prevention Clinical Decision Support Tool
This study highlights the features and usability offall prevention CDS for helping primary care providers deliver patient-centeredfall prevention care.PMID:38222393 | PMC:PMC10785844 (Source: AMIA Annual Symposium Proceedings)
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Christian J Tejeda Pamela M Garabedian Hannah Rice Lipika Samal Nancy K Latham Patricia C Dykes Source Type: research

Extracting Thyroid Nodules Characteristics from Ultrasound Reports Using Transformer-based Natural Language Processing Methods
This study lays ground for assessing the documentation quality of thyroid ultrasound reports and examining outcomes of patients with thyroid nodules using electronic health records.PMID:38222394 | PMC:PMC10785862 (Source: AMIA Annual Symposium Proceedings)
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Aman Pathak Zehao Yu Daniel Paredes Elio Paul Monsour Andrea Ortiz Rocha Juan P Brito Naykky Singh Ospina Yonghui Wu Source Type: research

Use of Health Belief Model-based Deep Learning to Understand Public Health Beliefs in Breast Cancer Screening from Social Media before and during the COVID-19 Pandemic
AMIA Annu Symp Proc. 2024 Jan 11;2023:280-288. eCollection 2023.ABSTRACTBreast cancer is the second leading cause of cancer death for women in the United States. While breast cancer screening participation is the most effective method for early detection, screening rate has remained low. Given that understanding health perception is critical to understand health decisions, our study utilized the Health Belief Model-based deep learning method to predict and examine public health beliefs in breast cancer and its screening behavior. The results showed that the trends in public health perception are sensitive to political (i.e...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Michelle Bak Chieh-Li Chin Jessie Chin Source Type: research

Identification of Outcome-Oriented Progression Subtypes from Mild Cognitive Impairment to Alzheimer's Disease Using Electronic Health Records
In this study, we proposed an outcome-oriented model to identify progression pathways from mild cognitive impairment (MCI) to AD using electronic health records (EHRs) from the OneFlorida+ Clinical Research Consortium. To achieve this, we employed the long short-term memory (LSTM) network to extract relevant information from the sequential records of each patient. The hierarchical agglomerative clustering was then applied to the learned representation to group patients based on their progression subtypes. Our approach identified multiple progression pathways, each of which represented distinct patterns of disease progressi...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Jie Xu Rui Yin Yu Huang Hannah Gao Yonghui Wu Jingchuan Guo Glenn E Smith Steven T DeKosky Fei Wang Yi Guo Jiang Bian Source Type: research

Characterizing Autism Spectrum Disorder and Predicting Suicide Risk for Pediatric Psychiatric Emergency Services Encounters
This study sought to characterize and classify youth presenting to the psychiatric emergency department (ED) for a chief complaint of STB. The results of this study validated that a high number of patients with ASD present to the ED with STB. There were important differences in clinical characteristics to those with ASD versus those without. Clinical features that showed important impact in predicting high suicide risk in the ASD cases include elements of the mental status exam such as affect, trauma symptoms, abuse history, and auditory hallucinations. Focused attention is needed on these unique differences in ASD cases s...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Katherine A Brown Kathleen R Donise Mary Kathryn Cancilliere Dilum P Aluthge Elizabeth S Chen Source Type: research

Prediction of Transfusion among In-patient Population using Temporal Pattern based Clinical Similarity Graphs
AMIA Annu Symp Proc. 2024 Jan 11;2023:679-688. eCollection 2023.ABSTRACTIntelligent prediction of risk of blood transfusion among hospitalized patients can identify at-risk patients and provide timely information to the hospital to plan and reserve resources to meet the demand of blood transfusion. While previously proposed solutions focus on sub-populations such as patients admitted to ICU after gastrointestinal bleeding or postpartum patients with hemorrhage, we design a predictive model applicable to complete in-patient population. Our model relies on patients' similarity graph based on temporal patterns among clinical ...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Amara Tariq Leon Su Bhavik Patel Imon Banerjee Source Type: research

Information Seeking and Sensemaking in Emergency Medical Service through Simulation Video Review
AMIA Annu Symp Proc. 2024 Jan 11;2023:804-813. eCollection 2023.ABSTRACTEmergency medical services (EMS) providers often face significant challenges in their work, including collecting, integrating, and making sense of a variety of information. Despite their criticality, EMS work is one of the very few medical domains with limited technical support. To design and implement effective decision support, it is essential to examine and gain a holistic understanding of the fine-grained process of sensemaking in the field. To that end, we reviewed 25 video recordings of EMS simulations to understand the nuances of EMS sensemaking...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Zhan Zhang Karen Joy Aastha S Bhadani Tejas D Joshi Kathleen Adelgais Mustafa Ozkaynak Source Type: research

Leveraging A Clinical Dashboard and Process Mappings to Improve Treatment Access and Outcomes for Women Veterans with Urinary Incontinence
AMIA Annu Symp Proc. 2024 Jan 11;2023:359-368. eCollection 2023.ABSTRACTIn support of the Improving Primary Care Understanding of Resources and Screening for Urinary Incontinence to Enhance Treatment initiative with the Veterans Health Administration, we developed a clinical dashboard to support primary care providers in identifying underdiagnosed, undertreated women Veterans with urinary incontinence. This paper describes our dashboard development and evaluation. We employed a user-centered design in determining dashboard requirements, interface design, and functionality. We invited early users at three pilot sites to for...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Grace Gao Camille P Vaughan Alayne D Markland Kayla Reinicke Neeraja Annavaram Zachary Burningham Source Type: research

Creating Augmented Reality Holograms for Polytrauma Patients Using 3D Slicer and Holomedicine Medical Image Platform
AMIA Annu Symp Proc. 2024 Jan 11;2023:663-668. eCollection 2023.ABSTRACTIn traumatology physicians heavily rely on computed tomography (CT) 2D axial scans to identify and assess the patient's injuries after an accident. However, in some cases it can be difficult to rigorously evaluate the real extent of the damage considering only the bidimensional slices produced by the CT, and some life-threatening lesions can be missed. With the development of 3D holographic rendering and extended reality (XR) technology, CT images can be projected in a 3D format through head-mounted holographic displays, allowing multi-view from differ...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Wei-Shao Sun Chun-Chuan Sun Lorenzo Porta Ting-Kai Yang Shih-Hao Su Shih-Hung Liu Tsung-Hsin Chou Shyr-Chyr Chen Joshua Ho Chien-Chang Lee Source Type: research

Co-designing mind-body technologies for sleep with adolescents
AMIA Annu Symp Proc. 2024 Jan 11;2023:1257-1266. eCollection 2023.ABSTRACTSleep is critical for well-being, yet adolescents do not get enough sleep. Mind-body approaches can help. Despite the potential of technology to support mind-body approaches for sleep, there is a lack of research on adolescent preferences for digital mind-body technology. We use co-design to examine adolescent perspectives on mind-body technologies for sleep. From our analysis of design sessions with 16 adolescents, four major themes emerged: system behavior, modality, content, and context. In light of these key findings, we recommend that technology...
Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Savitha Sangameswaran Megan Laine Nick Reid Serena Jinchen Xie Liz Zampino Michelle M Garrison Dori E Rosenberg Jason C Yip Andrea L Hartzler Source Type: research