American Journal of Physiology. Renal Physiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The kidney in health and disease in 2022: Gaps in and opportunities for new knowledge
Am J Physiol Renal Physiol. 2023 Dec 22. doi: 10.1152/ajprenal.00387.2023. Online ahead of print.NO ABSTRACTPMID:38134233 | DOI:10.1152/ajprenal.00387.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - December 22, 2023 Category: Physiology Authors: Kate M Denton Source Type: research

Current Perspective on Circadian Function of the Kidney
Am J Physiol Renal Physiol. 2023 Dec 22. doi: 10.1152/ajprenal.00247.2023. Online ahead of print.ABSTRACTBehavior and function of living systems are synchronized by the 24-hour rotation of the earth that guides physiology according to time of day. However, when behavior becomes misaligned from the light/dark cycle, such as in rotating shift work, jet lag, and even unusual eating patterns, adverse health consequences such as cardiovascular or cardiometabolic disease can arise. The discovery of cell autonomous molecular clocks expanded interest in regulatory systems that control circadian physiology including within the kidn...
Source: American Journal of Physiology. Renal Physiology - December 22, 2023 Category: Physiology Authors: Jazmine I Benjamin David M Pollock Source Type: research

L-carnitine pretreatment ameliorates heat stress-induced acute kidney injury by restoring mitochondrial function of tubular cells
In conclusion, carnitine insufficiency may be closely associated with severe heat-related illness and related AKI. Enhancement of the FAO pathway by L-carnitine pretreatment may prevent heat stress-induced AKI by restoring mitochondrial function.PMID:38095023 | DOI:10.1152/ajprenal.00196.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - December 14, 2023 Category: Physiology Authors: Hiroyasu Goto Hiroyuki Nakashima Kazuma Mori Keiko Tanoue Seigo Ito Bradley M Kearney Azusa Kato Masahiro Nakashima Toshihiko Imakiire Hiroo Kumagai Manabu Kinoshita Naoki Oshima Source Type: research

Beast of (renal) Burden? Bst1 expressing neutrophils in kidney injury
Am J Physiol Renal Physiol. 2023 Dec 14. doi: 10.1152/ajprenal.00386.2023. Online ahead of print.NO ABSTRACTPMID:38095024 | DOI:10.1152/ajprenal.00386.2023 (Source: American Journal of Physiology. Renal Physiology)
Source: American Journal of Physiology. Renal Physiology - December 14, 2023 Category: Physiology Authors: Jason A Collett David P Basile Source Type: research

A Combination of ß-Hydroxybutyrate and Citrate Ameliorates Disease Progression in a Rat Model of Polycystic Kidney Disease
Am J Physiol Renal Physiol. 2023 Dec 14. doi: 10.1152/ajprenal.00205.2023. Online ahead of print.ABSTRACTOur research has shown that interventions producing a state of ketosis are highly effective in rat, mouse, and cat models of polycystic kidney disease (PKD), preventing and partially reversing cyst growth and disease progression. The ketone ß-hydroxybutyrate (BHB) appears to underlie this effect. Additionally, we have demonstrated that naturally formed microcrystals within kidney tubules trigger a renoprotective response that facilitates tubular obstruction clearance in healthy animals but, alternatively, leads to cyst...
Source: American Journal of Physiology. Renal Physiology - December 14, 2023 Category: Physiology Authors: Jacob A Torres Nickolas Holznecht David A Asplund Tselmeg Amarlkhagva Bradley Kroes Juliette Rebello Shagun Agrawal Thomas Weimbs Source Type: research

Arginine Vasopressin regulates the renal Na-Cl and Na-K-Cl Cotransporters through With-No-Lysine Kinase 4 and Inhibitor 1 Phosphorylation
Am J Physiol Renal Physiol. 2023 Dec 14. doi: 10.1152/ajprenal.00343.2023. Online ahead of print.ABSTRACTVasopressin regulates water homeostasis via the V2 receptor in the kidney at least in part through protein kinase A (PKA) activation. Vasopressin, through an unknown pathway, upregulates the activity and phosphorylation of the Na+-Cl- cotransporter (NCC) and Na+-K+-2Cl- cotransporter 2 (NKCC2) by Ste20-related Proline/Alanine rich Kinase (SPAK) and Oxidative Stress Responsive kinase 1 (OSR1), which are regulated by the With No Lysine (K) kinase (WNK) family. Phosphorylation of WNK4 at PKA consensus motifs may be involve...
Source: American Journal of Physiology. Renal Physiology - December 14, 2023 Category: Physiology Authors: H éctor Carbajal-Contreras Adrian Rafael Murillo-de-Ozores Germ án Magaña-Avila Alejandro Marquez-Salinas Laurent Bourqui Michelle Tellez-Sutterlin Jessica P Bahena-Lopez Eduardo Cortes-Arroyo Sebasti án González-Behn-Eschemburg Alejandro Lopez-Saave Source Type: research