American Journal of Physiology. Regulatory, Integrative and Comparative Physiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

 Expression of Prolyl Hydroxylase Domains (PHDs), the upstream regulator of HIF, in the Brain of the Anoxia-Tolerant Crucian Carp during Anoxia-Reoxygenation
Am J Physiol Regul Integr Comp Physiol. 2023 Dec 25. doi: 10.1152/ajpregu.00211.2023. Online ahead of print.ABSTRACTThe hypoxia-inducible factor (HIF) is considered key in the transcriptional response to low oxygen. Yet, HIF's role in absence of oxygen (anoxia) and in preparation for reoxygenation remains unclear. Recent studies suggest that mounting a HIF response may be counterproductive for anoxia survival. We here studied the champion of anoxia survival, the crucian carp (Carassius carassius), and hypothesized that expression of prolyl hydroxylase domains, PHDs (the upstream regulators of HIF), are upregulated to circu...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - December 25, 2023 Category: Physiology Authors: Lucie Gerber Julien Resseguier Tellef Helle-Valle Elie Farhat G öran Erik Nilsson Sjannie Lefevre Source Type: research

Editorial for Call for papers: "Cardiovascular regulation during exercise: role of biological sex and consequences of aging."
Am J Physiol Regul Integr Comp Physiol. 2023 Dec 25. doi: 10.1152/ajpregu.00285.2023. Online ahead of print.NO ABSTRACTPMID:38145291 | DOI:10.1152/ajpregu.00285.2023 (Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology)
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - December 25, 2023 Category: Physiology Authors: Audrey J Stone Ann-Katrin Grotle Nina S Stachenfeld Source Type: research

CCK-sensitive C fibers activate NTS leptin receptor-expressing neurons via NMDA receptors
Am J Physiol Regul Integr Comp Physiol. 2023 Dec 18. doi: 10.1152/ajpregu.00238.2022. Online ahead of print.ABSTRACTThe hormone leptin reduces food intake through actions in the peripheral and central nervous system, including in the hindbrain nucleus of the solitary tract (NTS). The NTS receives viscerosensory information via vagal afferents, including information from the gastrointestinal tract, which is then relayed to other CNS sites critical for control of food intake. Leptin receptors (lepRs) are expressed by a subpopulation of NTS neurons, and knockdown of these receptors increases both food intake and body weight. ...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - December 18, 2023 Category: Physiology Authors: Drew Mackenzie Neyens Lynne Anne Brenner Rowan J Calkins Eric Thomas Winzenried Robert C Ritter Suzanne M Appleyard Source Type: research

Molecular basis of the unique osmoregulatory strategy in the inshore hagfish, Eptatretus burgeri 
Am J Physiol Regul Integr Comp Physiol. 2023 Dec 18. doi: 10.1152/ajpregu.00166.2023. Online ahead of print.ABSTRACTHagfishes are characterized by omo- and iono-conforming nature similar to marine invertebrates. Conventionally, hagfishes had been recognized as the most primitive living vertebrate that retains plesiomorphic features. However, some of the "ancestral" features of hagfishes, such as rudimentary eyes and the lack of vertebrae, have been proven to be deceptive. Similarly, by the principle of maximum parsimony, the unique body fluid regulatory strategy of hagfishes seems to be apomorphic, since the lamprey, anoth...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - December 18, 2023 Category: Physiology Authors: Yoko Yamaguchi Kiriko Ikeba Masa-Aki Yoshida Wataru Takagi Source Type: research

Facial fanning reduces heart rate but not tolerance to a simulated hemorrhagic challenge following exercise heat stress in young healthy humans
Am J Physiol Regul Integr Comp Physiol. 2023 Dec 18. doi: 10.1152/ajpregu.00180.2023. Online ahead of print.ABSTRACTWe investigated whether reducing face skin temperature alters arterial blood pressure control and lower body negative pressure (LBNP) tolerance after exercise heat stress. Eight subjects (1 female; age, 27 ± 9 years) exercised at ~63% VO2max until core temperature had increased ~1.5°C before undergoing LBNP to pre syncope either with fanning to return face skin temperature to baseline (∆-5°C, Fan trial) or without (No Fan trial). LBNP tolerance was quantified as cumulative stress index (CSI; mmHg*min). P...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - December 18, 2023 Category: Physiology Authors: Erica Tourula Miramani Lenzini Addison Rhodes Sarah E Hetz James Pearson Source Type: research