Chronic Villitis as a Distinctive Feature of Placental Injury in Maternal SARS-CoV-2 Infection
SARS-CoV-2 infection during pregnancy is associated with increased risk of stillbirth, preeclampsia and preterm birth. However, this does not appear to be due to intrauterine fetal infection, as vertical transmission is rarely reported. There is a paucity of data regarding associated placental SARS-CoV-2 histopathology and their relationship to timing and severity of infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 2, 2024 Category: OBGYN Authors: Lauryn C. GABBY, Chelsea K. JONES, Brendan B. MCINTYRE, Zoe MANALO, Morgan MEADS, Donald P. PIZZO, Jessica DIAZ-VIGIL, Francesca SONCIN, Kathleen M. FISCH, Gladys A. RAMOS, Marni B. JACOBS, Mana M. PARAST Tags: Original Research: Obstetrics Source Type: research

Maternal Mortality Review Committees should take a closer look at homicide deaths
The United States consistently falls behind comparable high-income countries in maternal mortality prevention.1 Violent causes of death outnumber obstetrical causes and homicide is now a leading cause of death of pregnant and postpartum women.2,3 These patterns have been documented for several years across many states in the United States.4 –6 Despite these consistent findings, most maternal mortality surveillance systems focus exclusively on obstetrical or medical causes of death, such as hemorrhage and infection. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 1, 2024 Category: OBGYN Authors: Melissa Bright, Alyssa Amendola, Dikea Roussos-Ross Tags: Editorial Source Type: research

Uterine isthmus contractions during pregnancy
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - April 1, 2024 Category: OBGYN Authors: Onur YAVUZ, İbrahim KARACA Tags: Letter to the Editors Source Type: research

Uterine isthmus contractions: real-time ultrasound
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 31, 2024 Category: OBGYN Authors: Alba FARR ÀS, Nerea MAIZ, Elena CARRERAS Tags: Letter to the Editors Source Type: research

Giant Nabothian Cysts Mimicking Genitourinary Fistula
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 29, 2024 Category: OBGYN Authors: Daniel Lieberman, Catherine Seaman, Anna Romanova, Emile Gleeson, Lisa Dabney Tags: Images in Gynecology Source Type: research

Cervical atresia and an obliterated upper vagina presenting as primary amenorrhea
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 28, 2024 Category: OBGYN Authors: Rebecca J. MEISER, Toni S. HORTON, Aakriti R. CARRUBBA, Sherif A. EL-NASHAR, Anita H. CHEN Tags: Images in Gynecology Source Type: research

Cost-effectiveness analysis of expectant versus active management for treatment of persistent pregnancies of unknown location
Persistent pregnancies of unknown location (PUL) are defined by abnormally trending serum human chorionic gonadotropin with nondiagnostic ultrasound. There is no consensus on optimal management. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 26, 2024 Category: OBGYN Authors: Jessica R. WALTER, Kurt T. BARNHART, Nathanael C. KOELPER, Nanette F. SANTORO, Heping ZHANG, Tracey R. THOMAS, Hao HUANG, Heidi S. HARVIE, NICHD Reproductive Medicine Network Tags: Original Research: Gynecology Source Type: research

The association between postpartum depressive symptoms and contraception
Postpartum depression affects 10-20% of birthing people and is associated with changes in healthcare utilization. Little is known about the association between postpartum depressive symptoms and choice to use contraception, however both un- or under-treated depression and short interpregnancy intervals pose significant perinatal health risks. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 26, 2024 Category: OBGYN Authors: Chloe N. MATOVINA, Allie SAKOWICZ, Emma C. ALLEN, May án I. ALVARADO-GOLDBERG, Danielle MILLAN, Emily S. MILLER Tags: Original Research: Gynecology Source Type: research

Enduring Safety Concerns for Out-Of-Hospital Births in the United States
(Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 25, 2024 Category: OBGYN Authors: Amos Gr ünebaum, Frank A. Chervenak Tags: Research Letter Source Type: research

Cefazolin as the mainstay for antibiotic prophylaxis in patients with a penicillin allergy in obstetrics and gynecology
Cefazolin is the most common antibiotic used for prophylaxis in obstetrics and gynecology. Among those with a penicillin allergy, alternative antibiotics are often chosen for prophylaxis, given fears of cross-reactivity between penicillin and cefazolin. Alternative antibiotics in this setting are associated with adverse sequelae, including surgical site infection, induction of bacterial resistance, higher costs to the healthcare system, and possible Clostridium difficile infection. Given the difference in R1 side chains between penicillin and cefazolin, cefazolin use is safe and should be recommended for patients with a pe...
Source: American Journal of Obstetrics and Gynecology - March 23, 2024 Category: OBGYN Authors: Karley J. Dutra, Gweneth B. Lazenby, Oluwatosin Goje, David E. Soper Tags: Clinical Opinion Source Type: research

Cefazolin as the Mainstay for Antibiotic Prophylaxis in Penicillin Allergic Patients in Obstetrics and Gynecology
Cefazolin is the most common antibiotic used for prophylaxis in obstetrics and gynecology. Among those with a penicillin allergy, alternative antibiotics are often chosen for prophylaxis given fears of cross-reactivity between penicillin and cefazolin. Alternative antibiotics in this setting are associated with adverse sequalae including surgical site infection, induction of bacterial resistance, higher costs to the healthcare system, and possible Clostridium difficile infection. Given the difference in R1 side chains between the penicillin and cefazolin, cefazolin use is safe and should be recommended for penicillin aller...
Source: American Journal of Obstetrics and Gynecology - March 23, 2024 Category: OBGYN Authors: Karley J. Dutra, Gweneth B. Lazenby, Oluwatosin Goje, David E. SOPER Tags: Clinical Opinion Source Type: research

Duration of biophysical profile in periviable and very preterm low-risk pregnancies
In recent years, perinatal viability has shifted from 24 to 22 weeks of gestation at many institutions after improvements in survival in neonates delivered at the limit of viability. Monitoring these fetuses is essential since antenatal interventions with resuscitation efforts are available for patients at risk of delivery at the limit of viability. However, fetal monitoring as biophysical profile has not been extensively studied in very preterm pregnancies, particularly in the periviable period (20 weeks 0 days – 23 weeks 6 days). (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 23, 2024 Category: OBGYN Authors: Luis M. Gomez, Laura Willingham, Jenny Wang, Sebastian Nasrallah, Michael B. Vandillen, Giancarlo Mari Tags: Original Research: Obstetrics Source Type: research

Contribution of Fetal Blood Sampling to Determining the Prognosis of Congenital Cytomegalovirus Infections: A Case-Cohort Study in Switzerland.
Cytomegalovirus is responsible for the most common congenital infection, affecting 0.5-1% of live births in Europe. Congenital CMV infection can be diagnosed during pregnancy by viral DNA amplification in the amniotic fluid, but the prognosis of fetuses without severe brain abnormalities remains difficult to establish based on prenatal imaging alone. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 23, 2024 Category: OBGYN Authors: L éo POMAR, Agathe CONTIER, Milos STOJANOV, Cécile GUENOT, Joanna SICHITIU, Anita C. TRUTTMANN, Yvan VIAL, David BAUD Tags: Original Research: Obstetrics Source Type: research

Embryo long-term storage does not affect ART outcome: analysis of 58001 vitrified blastocysts over an 11-year period.
Recently the potential detrimental effect that the duration of storage time may have on vitrified samples has raised some concern, especially when some studies found an association between cryo-storage length and decreased clinical results. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 23, 2024 Category: OBGYN Authors: Ana COBO, Aila COELLO, Mar ía J. DE LOS SANTOS, Jose REMOHI, Jose BELLVER Tags: Original Research: Gynecology Source Type: research

Defining Success After Surgical Treatment of Stress Urinary Incontinence
A consensus standardized definition of success after stress urinary incontinence surgical treatment is lacking, which precludes comparisons between studies and affects patient counseling. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - March 23, 2024 Category: OBGYN Authors: Rubin Raju, Annetta M. Madsen, Brian J. Linder, John A. Occhino, John B. Gebhart, Michaela E. McGree, Amy L. Weaver, Emanuel C. Trabuco Tags: Original Research: Gynecology Source Type: research