Afferent renal denervation attenuates sympathetic over activation from the paraventricular nucleus in spontaneously hypertensive rats
This study aimed to investigate the role of RDN in regulating cardiovascular function via the central Renin-Angiotensin System (RAS) pathway. Ten-week-old Spontaneously Hypertensive Rats (SHR) were subjected to Selective Afferent Renal Denervation (ADN) using capsaicin solution. We hypothesized that ADN would effectively reduce blood pressure and rebalance the RAS component of PVN in SHR. The experimental results show that ADN group exhibited significantly lower blood pressure, reduced systemic sympathetic activity, decreased chronic neuronal activation marker C-FOS expression in the paraventricular nucleus of hypothalamus...
Source: American Journal of Hypertension - March 9, 2024 Category: Cardiology Authors: Kun-Hui Li Jie-Min Lin Si-Qi Luo Min-Yan Li Yi-Yong Yang Meng-Meng Li Pan-Yan Xia Jin-Zi Su Source Type: research
Afferent renal denervation attenuates sympathetic over activation from the paraventricular nucleus in spontaneously hypertensive rats
This study aimed to investigate the role of RDN in regulating cardiovascular function via the central Renin-Angiotensin System (RAS) pathway. Ten-week-old Spontaneously Hypertensive Rats (SHR) were subjected to Selective Afferent Renal Denervation (ADN) using capsaicin solution. We hypothesized that ADN would effectively reduce blood pressure and rebalance the RAS component of PVN in SHR. The experimental results show that ADN group exhibited significantly lower blood pressure, reduced systemic sympathetic activity, decreased chronic neuronal activation marker C-FOS expression in the paraventricular nucleus of hypothalamus...
Source: American Journal of Hypertension - March 9, 2024 Category: Cardiology Authors: Kun-Hui Li Jie-Min Lin Si-Qi Luo Min-Yan Li Yi-Yong Yang Meng-Meng Li Pan-Yan Xia Jin-Zi Su Source Type: research
It's About Blood Pressure Reduction and Control
Am J Hypertens. 2024 Mar 6:hpae023. doi: 10.1093/ajh/hpae023. Online ahead of print.NO ABSTRACTPMID:38447001 | DOI:10.1093/ajh/hpae023 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 6, 2024 Category: Cardiology Authors: Eric J MacLaughlin Joseph J Saseen Source Type: research
It's About Blood Pressure Reduction and Control
Am J Hypertens. 2024 Mar 6:hpae023. doi: 10.1093/ajh/hpae023. Online ahead of print.NO ABSTRACTPMID:38447001 | DOI:10.1093/ajh/hpae023 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 6, 2024 Category: Cardiology Authors: Eric J MacLaughlin Joseph J Saseen Source Type: research
It's About Blood Pressure Reduction and Control
Am J Hypertens. 2024 Mar 6:hpae023. doi: 10.1093/ajh/hpae023. Online ahead of print.NO ABSTRACTPMID:38447001 | DOI:10.1093/ajh/hpae023 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 6, 2024 Category: Cardiology Authors: Eric J MacLaughlin Joseph J Saseen Source Type: research
Cardio-Ankle Vascular Index As A Marker Of Left Ventricular Hypertrophy In Treated Hypertensives: Findings From The Pamela Study
CONCLUSIONS: Our study provides new evidence of an independent association between CAVI and LVH in treated elderly hypertensive patients and suggests that the use of this metric of arterial stiffness could not only be used to evaluate vascular damage but also to stratify the risk of LVH.PMID:38441300 | DOI:10.1093/ajh/hpae022 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 5, 2024 Category: Cardiology Authors: Cesare Cuspidi Rita Facchetti Fosca Quarti-Trevano Raffaella Dell'Oro Giuseppe Mancia Guido Grassi Source Type: research
Cardio-Ankle Vascular Index As A Marker Of Left Ventricular Hypertrophy In Treated Hypertensives: Findings From The Pamela Study
CONCLUSIONS: Our study provides new evidence of an independent association between CAVI and LVH in treated elderly hypertensive patients and suggests that the use of this metric of arterial stiffness could not only be used to evaluate vascular damage but also to stratify the risk of LVH.PMID:38441300 | DOI:10.1093/ajh/hpae022 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 5, 2024 Category: Cardiology Authors: Cesare Cuspidi Rita Facchetti Fosca Quarti-Trevano Raffaella Dell'Oro Giuseppe Mancia Guido Grassi Source Type: research
Real-world Impact of Blood Pressure Control in Patients With Apparent Treatment-Resistant or Difficult-to-control Hypertension and Stages 3 and 4 Chronic Kidney Disease
CONCLUSIONS: Patients with aTRH and stage 3-4 CKD and uncontrolled BP despite treatment with ≥3 antihypertensive classes had an increased risk of MACE+ and ESRD and incurred greater healthcare resource utilization and medical expenditures compared with patients taking ≥3 antihypertensive classes with controlled BP.PMID:38436491 | DOI:10.1093/ajh/hpae020 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 4, 2024 Category: Cardiology Authors: George Bakris Cindy Chen Alicia K Campbell Veronica Ashton Lloyd Haskell Mukul Singhal Source Type: research
Real-world Impact of Blood Pressure Control in Patients With Apparent Treatment-Resistant or Difficult-to-control Hypertension and Stages 3 and 4 Chronic Kidney Disease
CONCLUSIONS: Patients with aTRH and stage 3-4 CKD and uncontrolled BP despite treatment with ≥3 antihypertensive classes had an increased risk of MACE+ and ESRD and incurred greater healthcare resource utilization and medical expenditures compared with patients taking ≥3 antihypertensive classes with controlled BP.PMID:38436491 | DOI:10.1093/ajh/hpae020 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 4, 2024 Category: Cardiology Authors: George Bakris Cindy Chen Alicia K Campbell Veronica Ashton Lloyd Haskell Mukul Singhal Source Type: research
Correction to: An Intersectoral Approach to Hypertension Care: Solutions for Improving Blood Pressure Control in S ão Paulo, Brazil
Am J Hypertens. 2024 Mar 2:hpae019. doi: 10.1093/ajh/hpae019. Online ahead of print.NO ABSTRACTPMID:38431283 | DOI:10.1093/ajh/hpae019 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - March 2, 2024 Category: Cardiology Source Type: research
A 120-Minute Saline Infusion Test For The Confirmation Of Primary Aldosteronism: A Pilot Study
CONCLUSIONS: A PAC of 397 pmol/l (14 ng/dL) at t=120 has high sensitivity and specificity for primary aldosteronism confirmation.PMID:38374690 | DOI:10.1093/ajh/hpae017 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 20, 2024 Category: Cardiology Authors: T Golani J Bleier A Kaplan T Hod Y Sharabi A Leibowitz E Grossman G Shlomai Source Type: research
A 120-Minute Saline Infusion Test For The Confirmation Of Primary Aldosteronism: A Pilot Study
CONCLUSIONS: A PAC of 397 pmol/l (14 ng/dL) at t=120 has high sensitivity and specificity for primary aldosteronism confirmation.PMID:38374690 | DOI:10.1093/ajh/hpae017 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 20, 2024 Category: Cardiology Authors: T Golani J Bleier A Kaplan T Hod Y Sharabi A Leibowitz E Grossman G Shlomai Source Type: research
A 120-Minute Saline Infusion Test For The Confirmation Of Primary Aldosteronism: A Pilot Study
CONCLUSIONS: A PAC of 397 pmol/l (14 ng/dL) at t=120 has high sensitivity and specificity for primary aldosteronism confirmation.PMID:38374690 | DOI:10.1093/ajh/hpae017 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 20, 2024 Category: Cardiology Authors: T Golani J Bleier A Kaplan T Hod Y Sharabi A Leibowitz E Grossman G Shlomai Source Type: research
A 120-Minute Saline Infusion Test For The Confirmation Of Primary Aldosteronism: A Pilot Study
CONCLUSIONS: A PAC of 397 pmol/l (14 ng/dL) at t=120 has high sensitivity and specificity for primary aldosteronism confirmation.PMID:38374690 | DOI:10.1093/ajh/hpae017 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 20, 2024 Category: Cardiology Authors: T Golani J Bleier A Kaplan T Hod Y Sharabi A Leibowitz E Grossman G Shlomai Source Type: research
A 120-Minute Saline Infusion Test For The Confirmation Of Primary Aldosteronism: A Pilot Study
CONCLUSIONS: A PAC of 397 pmol/l (14 ng/dL) at t=120 has high sensitivity and specificity for primary aldosteronism confirmation.PMID:38374690 | DOI:10.1093/ajh/hpae017 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - February 20, 2024 Category: Cardiology Authors: T Golani J Bleier A Kaplan T Hod Y Sharabi A Leibowitz E Grossman G Shlomai Source Type: research
