Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 11, 2017 Category: Hematology Authors: Marina Jerebtsova, Santosh L. Saraf, Xionghao Lin, Gillian Lee, Elena Afia Adjei, Namita Kumari, Nowah Afangbedji, Rasha Raslan, Charlee McLean, Victor R. Gordeuk, Sergei Nekhai Tags: Correspondence Source Type: research

A key role for Rac and Pak signaling in Neutrophil Extracellular Traps (NETs) formation defines a new potential therapeutic target
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 10, 2017 Category: Hematology Authors: M Gavillet, K Martinod, R Renella, DD Wagner, DA Williams Tags: Research Article Source Type: research

MECOM, HBS1L ‐MYB, THRB‐RARB, JAK2, and TERT polymorphisms defining the genetic predisposition to myeloproliferative neoplasms: A study on 939 patients
In conclusion, JAK2 46/1, TERT rs2736100 and MECOM rs2201862 are the chief predisposing polymorphisms to MPN. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 10, 2017 Category: Hematology Authors: Adrian P. Trifa, Claudia B ănescu, Anca S. Bojan, Cristian M. Voina, Ștefana Popa, Simona Vișan, Alina D. Ciubean, Florin Tripon, Delia Dima, Viola M. Popov, Ștefan C. Vesa, Mihaela Andreescu, Tünde Török‐Vistai, Romeo G. Mihăilă, Nicoleta Berb Tags: RESEARCH ARTICLE Source Type: research

Safety and Efficacy of Early Start of Iron Chelation Therapy with Deferiprone in Young Children Newly Diagnosed with Transfusion ‐Dependent Thalassemia: A Randomized Controlled Trial
This study investigated whether deferiprone, a chelator with a lower affinity for iron than deferoxamine, could postpone transfusional iron overload while maintaining a good safety profile. Recently diagnosed TDT infants (N=64 their age ranged from10‐18 (median 12) months, 54.7% males; receiving 400‐ 1000 µg/L and TSAT > 70% compared with none in the ES‐DFP group. LPI level>0.6 µM was observed in 97% vs. 40% of the DS and ES groups, respectively, (p1000 µg/L was delayed by 6 months in the ES‐DFP group (P
Source: American Journal of Hematology - November 9, 2017 Category: Hematology Authors: Mohsen Saleh Elalfy, Amira Adly, Hanem Awad, Mohamed Tarif Salam, Vasilios Berdoukas, Fernando Tricta Tags: Research Article Source Type: research

Hispanic ethnicity as a risk factor for requiring glucarpidase rescue in pediatric patients receiving high ‐dose methotrexate
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 9, 2017 Category: Hematology Authors: Eric S. Schafer, M. Brooke Bernhardt, Kate E. Reichert, Tara E. Haworth, Mona D. Shah Tags: Correspondence Source Type: research

A Phase I Study of Lenalidomide plus Chemotherapy with Mitoxantrone, Etoposide, and Cytarabine for the Reinduction of Patients with Acute Myeloid Leukemia
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 9, 2017 Category: Hematology Authors: Daniel J. DeAngelo, Andrew M. Brunner, Lillian Werner, David Avigan, Amir T. Fathi, Adam S. Sperling, Abigail Washington, Dina Stroopinsky, Jacalyn Rosenblatt, Malgorzata McMasters, Katarina Luptakova, Martha Wadleigh, David P. Steensma, Gabriela S. Hobbs Tags: Research Article Source Type: research

The Risk of Venous Thromboembolism in Patients with Clinically Overt Gastrointestinal Bleeding
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 9, 2017 Category: Hematology Authors: Mohammed Almakadi, Christopher Sheasgreen, Ahmed Barefah, Lucy Lu, Nidhi Kumar Tyagi, Gillian Mazzetti, Lindsay Crabbe, Yuhong Yuan, Mark Crowther, Grigorios Leontiadis Tags: Correspondence Source Type: research

Donor age determines outcome in acute leukemia patients over 40 undergoing haploidentical hematopoietic cell transplantation
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 8, 2017 Category: Hematology Authors: Jonathan Canaani, Bipin N Savani, Myriam Labopin, Xiao ‐jun Huang, Fabio Ciceri, William Arcese, Yener Koc, Johanna Tischer, Didier Blaise, Zafer Gülbas, Maria Teresa Van Lint, Benedetto Bruno, Mohamad Mohty, Arnon Nagler Tags: Research Article Source Type: research

Excess Mortality Among Ten ‐Year Survivors of Classical Hodgkin Lymphoma in Adolescents and Young Adults
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 8, 2017 Category: Hematology Authors: Ana C. Xavier, Narendranath Epperla, Jeffrey W. Taub, Luciano J. Costa Tags: Research Article Source Type: research

Hairy cell leukemia 2018: Update on diagnosis, risk ‐stratification, and treatment
Abstract Disease overviewHairy cell leukemia (HCL) and HCL‐like disorders, including HCL variant (HCL‐V) and splenic diffuse red pulp lymphoma (SDRPL), are a very heterogeneous group of mature lymphoid B‐cell disorders, characterized by the identification of hairy cells, a specific genetic profile, a different clinical course and the need for appropriate treatment. DiagnosisDiagnosis of HCL is based on morphological evidence of hairy cells, an HCL immunologic score of 3 or 4 based on the CD11C, CD103, CD123, and CD25 expression, the trephine biopsy which makes it possible to specify the degree of tumoral medullary in...
Source: American Journal of Hematology - November 7, 2017 Category: Hematology Authors: Xavier Troussard, Edouard Cornet Tags: ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES Source Type: research

Issue Information – Table of Contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 7, 2017 Category: Hematology Tags: ISSUE INFORMATION – TABLE OF CONTENTS Source Type: research

Therapy related ‐chronic myelomonocytic leukemia (CMML): Molecular, cytogenetic, and clinical distinctions from de novo CMML
Abstract Therapy related myeloid neoplasms (t‐MN) including therapy related myelodysplastic syndromes (t‐MDS) and acute myeloid leukemia (t‐AML) are associated with aggressive disease biologies and poor outcomes. In this large (n = 497) and informative (inclusive of molecular and cytogenetic information) chronic myelomonocytic leukemia (CMML) patient cohort, we demonstrate key biological insights and an independent prognostic impact for t‐CMML. T‐CMML was diagnosed in 9% of patients and occurred approximately 7 years after exposure to prior chemotherapy and/or radiation therapy. In comparison to de ...
Source: American Journal of Hematology - November 3, 2017 Category: Hematology Authors: Mrinal M. Patnaik, Rangit Vallapureddy, Fevzi F. Yalniz, Curtis A. Hanson, Rhett P. Ketterling, Terra L. Lasho, Christy Finke, Aref Al ‐Kali, Naseema Gangat, Ayalew Tefferi Tags: RESEARCH ARTICLE Source Type: research

Transformation of MDS/MPN ‐RS‐T to AML: Trisomy 13, resistant thrombocytosis and transient disease control with oral busulfan therapy
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 3, 2017 Category: Hematology Authors: Aisling Barrett, Mark Catherwood, Patrick Thornton, Philip Murphy, John Quinn Tags: CORRESPONDENCE Source Type: research

Outgrowing the Laboratory Diagnosis of Type 1 Von Willebrand Disease: A Two Decade Study
Abstract Von Willebrand Factor (VWF) levels are known to increase with age in the general population, but that effect is unclear in von Willebrand's disease (VWD) patients. Thus, it is important to assess the trends of VWF levels with age, and the extent and rate of their normalization in patients with VWD. In a retrospective cohort study, we reviewed the medical records of 126 patients between 1996 and 2016 who met the NHLBI diagnostic criteria for Type 1 VWD or “Low VWF” (LVWF). We followed all their historically documented VWF antigen (VWF:Ag), VWF activity (VWF:RCo), and Factor VIII (FVIII) levels longitudi...
Source: American Journal of Hematology - November 3, 2017 Category: Hematology Authors: Mouhamed Yazan Abou ‐Ismail, Gbolahan O. Ogunbayo, Michelle Secic, Peter A. Kouides Tags: Research Article Source Type: research

Comparison between the cll ‐ipi and the barcelona‐brno prognostic model: Analysis of 1299 newly diagnosed cases
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 3, 2017 Category: Hematology Authors: Massimo Gentile, Tait D Shanafelt, Francesca R Mauro, Luca Laurenti, Davide Rossi, Stefano Molica, Iolanda Vincelli, Giovanna Cutrona, Giuseppina Uccello, Sara Pepe, Ernesto Vigna, Giovanni Tripepi, Kari G Chaffee, Sameer A Parikh, Sabrina Bossio, Anna Gr Tags: Correspondence Source Type: research

A descriptive study of the characteristics of older adults with sickle cell disease
(Source: American Journal of Hematology)
Source: American Journal of Hematology - November 1, 2017 Category: Hematology Authors: Anjum B. Khan, Rachel Kesse ‐Adu, Cormac Breen C, Patrick B. Murphy, John Chambers, Paul Holmes P, Joanna Howard Tags: Correspondence Source Type: research

Mutations of the integrin αIIb/β3 intracytoplasmic salt bridge cause macrothrombocytopenia and enlarged platelet α‐granules
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 1, 2017 Category: Hematology Authors: Marie Favier, Jean ‐Claude Bordet, Remi Favier, Vasiliki Gkalea, Xavier Pillois, Philippe Rameau, Najet Debili, Marie‐Christine Alessi, Paquita Nurden, Hana Raslova, Alan Nurden Tags: Research Article Source Type: research

Demographics and patient characteristics of 1209 patients with Gaucher Disease: Descriptive analysis from the Gaucher Outcome Survey (GOS)
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 1, 2017 Category: Hematology Authors: Ari Zimran, Nadia Belmatoug, Bruno Bembi, Patrick Deegan, Deborah Elstein, Diego Fernandez ‐Sasso, Pilar Giraldo, Ozlem Goker‐Alpan, Heather Lau, Elena Lukina, Zoya Panahloo, Ida Vanessa D. Schwartz, Tags: Research Article Source Type: research

Results of a Phase 1 Study of Quizartinib as Maintenance Therapy in Subjects With Acute Myeloid Leukemia in Remission Following Allogeneic Hematopoietic Stem Cell Transplant
This study demonstrated acceptable tolerability and early evidence of reduced relapse rate following allo‐HCT with quizartinib maintenance compared to historical cohorts. No MTD was identified, but 60 mg daily was selected as highest dose for continuous daily administration based on randomized comparison of daily 30 and 60 mg doses in relapsed/refractory AML. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - November 1, 2017 Category: Hematology Authors: Brenda M. Sandmaier, Samer Khaled, Bet ül Oran, Guy Gammon, Denise Trone, Olga Frankfurt Tags: Research Article Source Type: research

Relatively favorable outcome after allogeneic stem cell transplantation for BCR ‐ABL1‐positive AML: A survey from the acute leukemia working party of the European Society for blood and marrow transplantation (EBMT)
Abstract The aim of the study was to assess the role of allogeneic stem cell transplantation (SCT) in patients diagnosed with BCR‐ABL1‐positive acute myeloid leukemia (AML). Fifty‐seven patients (median age, 48 years, range: 19‐67) with BCR‐ABL1 positive AML undergoing SCT were identified. The majority of the patients (70%) received a TKI before the transplant. At SCT 48 patients were in CR (45 in CR1), while 9 patients were transplanted in a more advanced stage of the disease. MRD was negative (BCR‐ABL1/ABL 
Source: American Journal of Hematology - October 31, 2017 Category: Hematology Authors: Vladimir Lj Lazarevic, Myriam Labopin, Wu Depei, Ibrahim Yakoub ‐Agha, Anne Huynh, Per Ljungman, Nicolaas Schaap, Jan J. Cornelissen, Natacha Maillard, Pietro Pioltelli, Tobias Gedde‐Dahl, Stig Lenhoff, Mohamed Houhou, Jordi Esteve, Mohamad Mohty, Arn Tags: RESEARCH ARTICLE Source Type: research

A blastic plasmacytoid dendritic cell neoplasm ‐like phenotype identifies a subgroup of NPM1‐mutated AML patients with worse prognosis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 28, 2017 Category: Hematology Authors: Paola Minetto, Fabio Guolo, Marino Clavio, Annalisa Kunkl, Nicoletta Colombo, Enrico Carminati, Livia Giannoni, Filippo Ballerini, Roberto Massimo Lemoli, Marco Gobbi, Maurizio Miglino Tags: Correspondence Source Type: research

Impact of MYD88 Mutation Status in Waldenstr öm Macroglobulinemia
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 28, 2017 Category: Hematology Authors: Jithma P. Abeykoon, Jonas Paludo, Rebecca L. King, Stephen M. Ansell, Morie A. Gertz, Betsy R. LaPlant, Alese E. Halvorson, Wilson I. Gonsalves, David Dingli, Hong Fang, S. Vincent Rajkumar, Martha Q. Lacy, Rong He, Taxiarchis Kourelis, Craig B. Reeder, A Tags: Research Article Source Type: research

Efficacy of VDT PACE ‐like Regimens in Treatment of Relapsed/Refractory Multiple Myeloma
Abstract Experience with intensive chemotherapy for relapsed/refractory multiple myeloma (RRMM) using VDT PACE regimen and its modifications (VDT PACE‐like regimens‐VPLRs) outside TOTAL THERAPY trials is limited. We analyzed the outcomes of 141 patients with RRMM who received VPLRs at our center between 2006 and 2017 in an intent‐to‐treat analysis. Median age was 59.7 years and 66.7% of patients were male. A median of 2.2 years (range, 0.02‐11.4) separated diagnosis of myeloma and inititation of VPLR. High‐risk cytogenetics were present in 52.4% patients. Patients received a median of 4 (range, 1‐14) prior th...
Source: American Journal of Hematology - October 25, 2017 Category: Hematology Authors: Arjun Lakshman, Preet Paul Singh, S. Vincent Rajkumar, Angela Dispenzieri, Martha Q. Lacy, Morie A. Gertz, Francis K. Buadi, David Dingli, Yi Lisa Hwa, Amie L. Fonder, Miriam Hobbs, Suzanne R. Hayman, Steven R. Zeldenrust, John A. Lust, Stephen J. Russell Tags: Research Article Source Type: research

Annual clinical updates in hematological malignancies: a continuing medical education series
American Journal of Hematology, EarlyView. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 25, 2017 Category: Hematology Source Type: research

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American Journal of Hematology, Ahead of Print. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 25, 2017 Category: Hematology Source Type: research

Annual clinical updates in hematological malignancies: a continuing medical education series
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 25, 2017 Category: Hematology Tags: ERRATUM Source Type: research

Lenalidomide therapy in patients with myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN ‐RS‐T)
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 25, 2017 Category: Hematology Authors: Maura Nicolosi, Mythri Mudireddy, Rangit Vallapureddy, Naseema Gangat, Ayalew Tefferi, Mrinal M. Patnaik Tags: Correspondence Source Type: research

Pediatric to adult care Co ‐location transitional model for youth with sickle cell disease
Abstract Among youth with sickle cell disease (SCD), morbidity and mortality substantially increase following departure from pediatric care. The purpose of this study was to investigate the efficacy of co‐location transitional model by comparing the rate of health care utilization pre‐ and post‐transfer to adult care and to evaluate the relation between disease specific knowledge and the co‐location model. All patients transferring from pediatric to adult care between October 2011 and December 2013, opting for the co‐location model to transition from pediatric to adult care in Memphis, TN were included in the ana...
Source: American Journal of Hematology - October 25, 2017 Category: Hematology Authors: Vikki G. Nolan, Sheila M. Anderson, Matthew P. Smeltzer, Jerlym S. Porter, Yvonne M. Carroll, Ian M. Brooks, Nada Elmagboul, James G. Gurney, Jane S. Hankins Tags: Correspondence Source Type: research

Diagnostic value of targeted next ‐generation sequencing in suspected hemochromatosis patients with a single copy of the HFE p.Cys282Tyr causative allele
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 23, 2017 Category: Hematology Authors: Kevin Uguen, Virginie Scotet, Chandran Ka, Isabelle Gourlaouen, Carine L'hostis, Marie ‐Christine Merour, Tania Cuppens, Claude Ferec, Gerald Le Gac Tags: CORRESPONDENCE Source Type: research

Characteristics of CLL patients achieving 5+ years of remission after FC ‐based first line treatment: Retrospective observations from the FILO group
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 21, 2017 Category: Hematology Authors: Yann Guillermin, Charles Herbaux, Fabien Subtil, Th érèse Aurran‐Schleinitz, Florence Cymbalista, Remi Letestu, Stéphane Leprêtre, Sandrine Vaudaux, Kamel Laribi, Véronique Leblond, Yasmina Defoi, Raouf Benchikh, Gilles Salles, Pascal Godmer, Henry Tags: Correspondence Source Type: research

Acute promyelocytic leukemia and chronic lymphocytic leukemia diagnosed concurrently
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 20, 2017 Category: Hematology Authors: Catherine C. Coombs, Stephanie P. Mathews Tags: Images in Hematology Source Type: research

Acute promyelocytic leukemia and chronic lymphocytic leukemia diagnosed concurrently
American Journal of Hematology,Volume 93, Issue 4, Page 595-596, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 20, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 595-596, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 20, 2017 Category: Hematology Source Type: research

Noninvasive monitoring of liver fibrosis in sickle cell disease: Longitudinal observation of a cohort of adult patients
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 20, 2017 Category: Hematology Authors: Valeria Maria Pinto, Barbara Gianesin, Manuela Balocco, Lorenzo Bacigalupo, Gian Luca Forni Tags: CORRESPONDENCE Source Type: research

A Randomized Controlled Trial Comparing Two Vaso ‐occlusive Episode (VOE) Protocols in Sickle Cell Disease (SCD)
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 19, 2017 Category: Hematology Authors: Paula Tanabe, Susan Silva, Hayden B. Bosworth, Regina Crawford, Judith A. Paice, Lynne D. Richardson, Christopher N. Miller, Jeffrey Glassberg Tags: Research Article Source Type: research

The Eutos long ‐term survival score accurately predicts the risk of death in chronic myeloid leukaemia patients treated outside of clinical trials
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 19, 2017 Category: Hematology Authors: Matteo Molica, Martina Canichella, Danilo Alunni Fegatelli, Gioia Colafigli, Fulvio Massaro, Roberto Latagliata, Robin Fo à, Massimo Breccia Tags: CORRESPONDENCE Source Type: research

Hyper ‐CVAD plus Nelarabine in Newly Diagnosed Adult T‐Cell Acute Lymphoblastic Leukemia and T‐Lymphoblastic Lymphoma
In conclusion, hyper‐CVAD plus nelarabine was well tolerated and active in the frontline treatment of adult T‐ALL/LBL patients. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 19, 2017 Category: Hematology Authors: Yasmin Abaza, Hagop M. Kantarjian, Stefan Faderl, Elias Jabbour, Nitin Jain, Deborah Thomas, Tapan Kadia, Gautam Borthakur, Joseph D. Khoury, Jan Burger, William Wierda, Susan O'Brien, Marina Konopleva, Alessandra Ferrajoli, Partow Kebriaei, Bouthaina Dab Tags: Research Article Source Type: research

MECOM, HBS1L ‐MYB, THRB‐RARB, JAK2 and TERT polymorphisms defining the genetic predisposition to myeloproliferative neoplasms ‐ a study on 939 patients
In conclusion, JAK2 46/1, TERT rs2736100 and MECOM rs2201862 are the chief predisposing polymorphisms to MPN. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 19, 2017 Category: Hematology Authors: Adrian P. Trifa, Claudia B ănescu, Anca S. Bojan, Cristian M. Voina, Ștefana Popa, Simona Vișan, Alina D. Ciubean, Florin Tripon, Delia Dima, Viola M. Popov, Ștefan C. Vesa, Mihaela Andreescu, Tünde Török‐Vistai, Romeo G. Mihăilă, Nicoleta Berb Tags: Research Article Source Type: research

Acute immune toxicity during anti ‐thymocyte globulin: That's CARPA!
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 19, 2017 Category: Hematology Authors: Serena Marotta, Patrizia Ricci, Luana Marano, Giuliana Beneduce, Orsola Vitagliano, Fiorenza De Gregorio, Francesco Grimaldi, Fabrizio Pane, Antonio M Risitano Tags: Correspondence Source Type: research

Donor lymphocyte infusion and methotrexate for immune recovery after T ‐cell depleted haploidentical transplantation
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 19, 2017 Category: Hematology Authors: Andrew L. Gilman, Wing Leung, Morton J. Cowan, Mark Cannon, Stacy Epstein, Carrie Barnhart, Krishna Shah, Michelle Hyland, Tracy Fukes, Anastasia Ivanova Tags: Research Article Source Type: research

World Health Organization ‐defined eosinophilic disorders: 2017 update on diagnosis, risk stratification, and management
Abstract Disease overviewThe eosinophilias encompass a broad range of nonhematologic (secondary or reactive) and hematologic (primary, clonal) disorders with potential for end‐organ damage. DiagnosisHypereosinophilia has generally been defined as a peripheral blood eosinophil count greater than 1500/mm3 and may be associated with tissue damage. After exclusion of secondary causes of eosinophilia, diagnostic evaluation of primary eosinophilias relies on a combination of morphologic review of the blood and marrow, standard cytogenetics, fluorescent in situ‐hybridization, flow immunocytometry, and T‐cell clonality asses...
Source: American Journal of Hematology - October 17, 2017 Category: Hematology Authors: Jason Gotlib Tags: ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES Source Type: research

Issue Information – Table of Contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 17, 2017 Category: Hematology Tags: ISSUE INFORMATION – TABLE OF CONTENTS Source Type: research

Lymphoplasmacytoid cytology in plasma cell leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 13, 2017 Category: Hematology Authors: Ahmad Khoder, Magda Al Obaidi, Natasha Wiles, Elisabet Nadal ‐Melsio, Barbara J. Bain Tags: Morphology Update Source Type: research

The athlete's hematological response to hypoxia: A meta ‐analysis on the influence of altitude exposure on key biomarkers of erythropoiesis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 13, 2017 Category: Hematology Authors: Louisa M. Lobigs, Ken Sharpe, Laura A. Garvican ‐Lewis, Christopher J. Gore, Peter Peeling, Brian Dawson, Yorck O. Schumacher Tags: Research Article Source Type: research

Revisiting the need for bone marrow examination in chronic myeloid leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 13, 2017 Category: Hematology Authors: Ayalew Tefferi, Curtis A. Hanson, Rhett P. Ketterling Tags: Commentary Source Type: research

Therapy Related ‐Chronic Myelomonocytic Leukemia (CMML): Molecular, Cytogenetic and Clinical Distinctions from de novo CMML
Abstract Therapy related myeloid neoplasms (t‐MN) including therapy related myelodysplastic syndromes (t‐MDS) and acute myeloid leukemia (t‐AML) are associated with aggressive disease biologies and poor outcomes. In this large (n=497) and informative (inclusive of molecular and cytogenetic information) chronic myelomonocytic leukemia (CMML) patient cohort, we demonstrate key biological insights and an independent prognostic impact for t‐CMML. T‐CMML was diagnosed in 9% of patients and occurred approximately 7 years after exposure to prior chemotherapy and/or radiation therapy. In comparison to de novo CMML, t‐C...
Source: American Journal of Hematology - October 11, 2017 Category: Hematology Authors: Mrinal M. Patnaik, Rangit Vallapureddy, Fevzi F. Yalniz, Curtis A. Hanson, Rhett P. Ketterling, Terra L Lasho, Christy Finke, Aref Al ‐Kali, Naseema Gangat, Ayalew Tefferi Tags: Research Article Source Type: research

Clinical management of peripherally inserted central catheters compared to conventional central venous catheters in patients with hematological malignancies: A large multicenter study of the REL GROUP (Rete Ematologica Lombarda ‐ Lombardy Hematologic Network, Italy)
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 10, 2017 Category: Hematology Authors: Nicola Stefano Fracchiolla, Elisabetta Todisco, Andrea Bilancia, Sara Gandolfi, Nicola Orofino, Francesca Guidotti, Valentina Mancini, Laura Marbello, Andrea Assanelli, Massimo Bernardi, Armando Santoro, Roberto Cairoli, Dario Consonni, Agostino Cortelezz Tags: CORRESPONDENCE Source Type: research

Correcting the cut ‐off point of hemoglobin at high altitude favors misclassification of anemia, erythrocytosis and excessive erythrocytosis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: Gustavo F. Gonzales, Ver ónica Rubín de Celis, José Begazo, María del Rosario Hinojosa, Sandra Yucra, Alisson Zevallos, Vilma Tapia Tags: Correspondence Source Type: research

Transformation of MDS/MPN ‐RS‐T to AML – Trisomy 13, Resistant Thrombocytosis and Transient Disease Control with Oral Busulfan Therapy
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: A. Barrett, M. Catherwood, P. Thornton, P. Murphy, J. Quinn Tags: Correspondence Source Type: research

Improved prognosis with additional medium ‐dose VP16 to CY/TBI in allogeneic transplantation for high risk ALL in adults
This study was the first to reveal the efficacy of the addition of medium‐dose VP16 to CY/TBI in high‐risk ALL. To establish new myeloablative conditioning regimens including VP16, a large‐scale prospective study is necessary. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: Yasuyuki Arai, Tadakazu Kondo, Akio Shigematsu, Junji Tanaka, Kazuteru Ohashi, Takahiro Fukuda, Michihiro Hidaka, Naoki Kobayashi, Koji Iwato, Toru Sakura, Makoto Onizuka, Yukiyasu Ozawa, Tetsuya Eto, Mineo Kurokawa, Kaoru Kahata, Naoyuki Uchida, Yoshiko Tags: Research Article Source Type: research