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American Journal of Hematology,Volume 93, Issue 4, Page 546-552, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - January 10, 2018 Category: Hematology Source Type: research

Factor VII deficiency in major artery occlusion stroke
(Source: American Journal of Hematology)
Source: American Journal of Hematology - January 10, 2018 Category: Hematology Authors: Slaven Pikija, Simon Peter Gampenrieder, Katharina Millesi, Georg Pilz, Serge Weis, Johannes Sebastian Mutzenbach Tags: Images in Hematology Source Type: research

Realizing Effectiveness Across Continents with Hydroxyurea: Enrollment and Baseline Characteristics of the Multicenter REACH Study in sub ‐Saharan Africa
Abstract Despite its well‐described safety and efficacy in the treatment of sickle cell anemia (SCA) in high‐income settings, hydroxyurea remains largely unavailable in sub‐Saharan Africa, where more than 75% of annual SCA births occur and many comorbidities exist. Realizing Effectiveness Across Continents with Hydroxyurea (REACH, ClinicalTrials.gov NCT01966731) is a prospective, Phase I/II open‐label trial of hydroxyurea designed to evaluate the feasibility, safety, and benefits of hydroxyurea treatment for children with SCA in four sub‐Saharan African countries. Following comprehensive training of local researc...
Source: American Journal of Hematology - January 10, 2018 Category: Hematology Authors: Patrick T. McGann, Thomas N. Williams, Peter Olupot ‐Olupot, George A. Tomlinson, Adam Lane, José Luís Reis da Fonseca, Robert Kitenge, George Mochamah, Ham Wabwire, Susan Stuber, Thad A. Howard, Kathryn McElhinney, Banu Aygun, Teresa Latham, Brígida Tags: Research Article Source Type: research

Description and Prognostic Significance of the Kinetics of Minimal Residual Disease Status in Adults with Acute Lymphoblastic Leukemia Treated with HyperCVAD
Abstract HyperCVAD is a commonly‐used regimen for adults with newly‐diagnosed acute lymphoblastic leukemia (ALL). However, relatively little is known about the application of minimal residual disease (MRD) detection with this treatment. To address this, we studied 142 adults with ALL treated with hyperCVAD over a 10‐year period who had MRD assessed by either multi‐parameter flow cytometry or (for patients with Philadelphia chromosome positive ALL) reverse transcriptase polymerase chain reaction for the BCR‐ABL1 translocation. In a multivariate analysis, patients who achieved MRD negativity (MRDNeg) at any point h...
Source: American Journal of Hematology - January 10, 2018 Category: Hematology Authors: Ryan D. Cassaday, Philip A. Stevenson, Brent L. Wood, Pamela S. Becker, Paul C. Hendrie, Brenda M. Sandmaier, Jerald L. Radich, Andrei R. Shustov Tags: Research Article Source Type: research

Lack of correlation between heart, liver and pancreas MRI ‐R2*: Results from long‐term follow‐up in a cohort of adult β‐thalassemia major patients
(Source: American Journal of Hematology)
Source: American Journal of Hematology - January 9, 2018 Category: Hematology Authors: Valeria Maria Pinto, Lorenzo Bacigalupo, Barbara Gianesin, Manuela Balocco, Lucia De Franceschi, Roberto Malag ò, John Wood, Gian Luca Forni Tags: CORRESPONDENCE Source Type: research

Follicular lymphoma: 2018 update on diagnosis and management
Abstract Disease overviewFollicular lymphoma is generally an indolent B cell lymphoproliferative disorder of transformed follicular center B cells. Follicular lymphoma (FL) is characterized by diffuse lymphadenopathy, bone marrow involvement, splenomegaly and less commonly other extranodal sites of involvement. In general, cytopenias can occur but constitutional symptoms of fever, nightsweats, and weight loss are uncommon. DiagnosisDiagnosis is based on histology of preferably a biopsy of a lymph node. Immunohistochemical staining is positive in virtually all cases for cell surface CD19, CD20, CD10, and monoclonal immunogl...
Source: American Journal of Hematology - January 8, 2018 Category: Hematology Authors: Arnold Freedman Tags: ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES Source Type: research

Issue information – table of contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - January 8, 2018 Category: Hematology Tags: ISSUE INFORMATION – TABLE OF CONTENTS Source Type: research

Reply to Castillo et al.
(Source: American Journal of Hematology)
Source: American Journal of Hematology - January 5, 2018 Category: Hematology Authors: Jithma P. Abeykoon, Rebecca King, Stephen M. Ansell, S. Vincent Rajkumar, Jonas Paludo, Robert A. Kyle, Shaji Kumar, Morie A. Gertz, Prashant Kapoor Tags: Correspondence Source Type: research

Toward complement inhibition 2.0: Next generation anticomplement agents for paroxysmal nocturnal hemoglobinuria
American Journal of Hematology,Volume 93, Issue 4, Page 564-577, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - January 4, 2018 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 564-577, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - January 4, 2018 Category: Hematology Source Type: research

Methylene blue ‐induced Heinz body hemolytic anemia in a premature neonate
(Source: American Journal of Hematology)
Source: American Journal of Hematology - January 1, 2018 Category: Hematology Authors: Lewis Vanhinsbergh, Sabita Uthaya, Barbara J. Bain Tags: Morphology Update Source Type: research

Toward complement inhibition 2.0: Next generation anti ‐complement agents for paroxysmal nocturnal hemoglobinuria
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - January 1, 2018 Category: Hematology Authors: Antonio M Risitano, Serena Marotta Tags: Updates in Clinical Trials for Hematological Diseases Source Type: research

FLT3 Inhibitors in Acute Myeloid Leukemia: Choosing the Best when the Optimal Does Not Exist
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Authors: Rita Assi, Farhad Ravandi Tags: Critical Review Source Type: research

FLT3 inhibitors in acute myeloid leukemia: Choosing the best when the optimal does not exist
American Journal of Hematology,Volume 93, Issue 4, Page 553-563, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Source Type: research

Centrifugation ‐free washing: A novel approach for removing immunoglobulin A from stored red blood cells
American Journal of Hematology,Volume 93, Issue 4, Page 518-526, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Source Type: research

Ataluren ‐driven restoration of Shwachman‐Bodian‐Diamond syndrome protein function in Shwachman‐Diamond syndrome bone marrow cells
American Journal of Hematology,Volume 93, Issue 4, Page 527-536, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 553-563, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 518-526, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 527-536, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Source Type: research

Centrifugation ‐free washing: A novel approach for removing IgA from stored red blood cells
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Authors: Eszter V örös, Nathaniel Z. Piety, Briony C. Strachan, Madeleine Lu, Sergey S. Shevkoplyas Tags: Research Article Source Type: research

Ataluren ‐driven Restoration of Shwachman‐Bodian‐Diamond Syndrome Protein Function in Shwachman‐Diamond Syndrome Bone Marrow Cells
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 29, 2017 Category: Hematology Authors: Valentino Bezzerri, Donatella Bardelli, Jacopo Morini, Antonio Vella, Simone Cesaro, Claudio Sorio, Andrea Biondi, Cesare Danesino, Piero Farruggia, Baroukh Maurice Assael, Giovanna D'Amico, Marco Cipolli Tags: Research Article Source Type: research

Fatal Cache Valley virus meningoencephalitis associated with rituximab maintenance therapy
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 28, 2017 Category: Hematology Authors: Yuanquan Yang, Jingxin Qiu, Abigail Snyder ‐Keller, Yongping Wu, Shufeng Sun, Haixin Sui, Amy B. Dean, Laura Kramer, Francisco Hernandez‐Ilizaliturri Tags: Solving Clinical Problems in Blood Diseases Source Type: research

Fatal Cache Valley virus meningoencephalitis associated with rituximab maintenance therapy
American Journal of Hematology,Volume 93, Issue 4, Page 590-594, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 28, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 590-594, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 28, 2017 Category: Hematology Source Type: research

Ibrutinib discontinuation in Waldenstr öm macroglobulinemia: etiologies, outcomes, and IgM rebound
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 27, 2017 Category: Hematology Authors: Joshua N. Gustine, Kirsten Meid, Toni Dubeau, Patricia Severns, Zachary R. Hunter, Guang Yang, Lian Xu, Steven P. Treon, Jorge J. Castillo Tags: Research Article Source Type: research

Ibrutinib discontinuation in Waldenstr öm macroglobulinemia: Etiologies, outcomes, and IgM rebound
American Journal of Hematology,Volume 93, Issue 4, Page 511-517, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 27, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 511-517, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 27, 2017 Category: Hematology Source Type: research

JAK2 exon 12 mutated polycythemia vera: Mayo ‐Careggi MPN Alliance study of 33 consecutive cases and comparison with JAK2V617F mutated disease
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: Ayalew Tefferi, Sravanthi Lavu, Mythri Mudireddy, Terra L. Lasho, Christy M. Finke, Naseema Gangat, Animesh Pardanani, Curtis A. Hanson, Carmela Mannarelli, Paola Guglielmelli, Alessandro M. Vannucchi Tags: Correspondence Source Type: research

Intestinal microbiome analysis revealed dysbiosis in sickle cell disease
American Journal of Hematology,Volume 93, Issue 4, Page E91-E93, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

A distinct immunophenotype identifies a subset of NPM1 ‐mutated AML with TET2 or IDH1/2 mutations and improved outcome
American Journal of Hematology,Volume 93, Issue 4, Page 504-510, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

JAK2 exon 12 mutated polycythemia vera: Mayo ‐Careggi MPN Alliance study of 33 consecutive cases and comparison with JAK2V617F mutated disease
American Journal of Hematology,Volume 93, Issue 4, Page E93-E96, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

Developmental differences between neonatal and adult human erythropoiesis
American Journal of Hematology,Volume 93, Issue 4, Page 494-503, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

A single center experience with romiplostim for the management of chemotherapy ‐induced thrombocytopenia
American Journal of Hematology,Volume 93, Issue 4, Page E86-E88, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

Prognostic impact of bone marrow fibrosis and dyserythropoiesis in autoimmune hemolytic anemia
American Journal of Hematology,Volume 93, Issue 4, Page E88-E91, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page E91-E93, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 504-510, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page E93-E96, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page 494-503, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page E86-E88, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page E88-E91, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Source Type: research

Developmental Differences Between Neonatal and Adult Human Erythropoiesis
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: Hongxia Yan, John Hale, Julie Jaffray, Jie Li, Yaomei Wang, Yumin Huang, Xiuli An, Christopher Hillyer, Nan Wang, Sandrina Kinet, Naomi Taylor, Narla Mohandas, Anupama Narla, Lionel Blanc Tags: Research Article Source Type: research

Sarcoid ‐like granulomatosis in a patient receiving anti‐TNFα for psoriasis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: Vasiliki Leventaki, Jamie Flerlage Tags: Images in Hematology Source Type: research

A Single Center Experience with Romiplostim for the Management of Chemotherapy ‐Induced Thrombocytopenia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: Jennifer Miao, Houry Leblebjian, Bridget Scullion, Aric Parnes Tags: Correspondence Source Type: research

Prognostic impact of bone marrow fibrosis and dyserythropoiesis in autoimmune hemolytic anemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: B Fattizzo, A Zaninoni, U Gianelli, A Zanella, A Cortelezzi, AG Kulasekararaj, W Barcellini Tags: Correspondence Source Type: research

Intestinal microbiome analysis revealed dysbiosis in sickle cell disease
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: Seah H Lim, Alison Morris, Kelvin Li, Adam C Fitch, Loren Fast, Laura Goldberg, Matthew Quesenberry, Philippa Sprinz, Barbara Meth é Tags: Correspondence Source Type: research

A Distinct Immunophenotype Identifies a Subset of NPM1 ‐mutated AML With TET2 or IDH1/2 Mutations and Improved Outcome
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 23, 2017 Category: Hematology Authors: Emily F. Mason, Frank C. Kuo, Robert P. Hasserjian, Adam C. Seegmiller, Olga Pozdnyakova Tags: Research Article Source Type: research

Clinical and biological characterization of MPN patients harboring two driver mutations, a French Intergroup of Myeloproliferative neoplasms (FIM) study
(Source: American Journal of Hematology)
Source: American Journal of Hematology - December 21, 2017 Category: Hematology Authors: Olivier Mansier, Damien Luque Paz, Jean ‐Christophe Ianotto, Yannick Le Bris, Aurélie Chauveau, Françoise Boyer, Carole Conejero, Olivier Fitoussi, Jérémie Riou, Didier Adiko, Mohamed Touati, Jasmine Chauzeix, Jean‐François Viallard, Marie C Bén Tags: Correspondence Source Type: research

Clinical and biological characterization of MPN patients harboring two driver mutations, a French intergroup of myeloproliferative neoplasms (FIM) study
American Journal of Hematology,Volume 93, Issue 4, Page E84-E86, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 21, 2017 Category: Hematology Source Type: research

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American Journal of Hematology,Volume 93, Issue 4, Page E84-E86, April 2018. (Source: American Journal of Hematology)
Source: American Journal of Hematology - December 21, 2017 Category: Hematology Source Type: research

Sleep disordered breathing does not predict acute severe pain episodes in children with sickle cell anemia
Abstract Conflicting evidence has suggested that low mean nocturnal hemoglobin oxygen saturation (SpO2) predicts future hospital days for acute severe pain in children with sickle cell anemia (SCA). In an unselected multi‐center prospective cohort study, we tested the hypothesis that either low mean nocturnal SpO2 or high obstructive apnea‐hypopnea index (OAHI; the number of obstructive apneas and hypopneas with ≥ 3% desaturation or arousal per hour of sleep) or high oxygen desaturation index (ODI; number of ≥ 3% desaturation from baseline saturation per hour of sleep) is associated wi...
Source: American Journal of Hematology - December 20, 2017 Category: Hematology Authors: Shaina M. Willen, Mark Rodeghier, Carol L. Rosen, Michael R. DeBaun Tags: Research Article Source Type: research