Issue Information – Table of Contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - March 12, 2017 Category: Hematology Tags: Issue Information – Table of Contents Source Type: research

Erythrocytes from Hereditary Xerocytosis patients heterozygous for KCNN4 V282M exhibit increased spontaneous Gardos channel ‐like activity inhibited by Senicapoc
(Source: American Journal of Hematology)
Source: American Journal of Hematology - March 9, 2017 Category: Hematology Authors: Alicia Rivera, David H. Vandorpe, Boris E. Shmukler, Denis R. Gallagher, Christopher C. Fikry, Frans A. Kuypers, Carlo Brugnara, L. Michael Snyder, Seth L. Alper Tags: Correspondence Source Type: research

Beyond the transition of adolescents and young adults with sickle cell disease to adult care: Role of geography
(Source: American Journal of Hematology)
Source: American Journal of Hematology - March 9, 2017 Category: Hematology Authors: Nina Anderson, James R. Eckman, Samir K. Ballas Tags: Correspondence Source Type: research

Incidence, clinical findings, and survival of hepatosplenic T ‐cell lymphoma in the United States
(Source: American Journal of Hematology)
Source: American Journal of Hematology - March 5, 2017 Category: Hematology Authors: Urshila Durani, Ronald S. Go Tags: Correspondence Source Type: research

The association between race and venous thromboembolism risk after initiation of chemotherapy: An analysis of the SAVE ‐ONCO Trial control arm
(Source: American Journal of Hematology)
Source: American Journal of Hematology - March 5, 2017 Category: Hematology Authors: Yu ‐Wei Chen, Alok Khorana Tags: Correspondence Source Type: research

Assessment of renal response with urinary exosomes in patients with AL amyloidosis: A proof of concept
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 28, 2017 Category: Hematology Authors: Marina Ramirez ‐Alvarado, David R. Barnidge, David L. Murray, Angela Dispenzieri, Marta Marin‐Argany, Christopher J. Dick, Shawna A. Cooper, Samih H Nasr, Christopher J. Ward, Surendra Dasari, Víctor H. Jiménez‐Zepeda, Nelson Leung Tags: Research Article Source Type: research

Myeloid Neoplasms with Concurrent BCR ‐ABL1 and CBFB Rearrangements: A Series of 10 Cases of a Clinically Aggressive Neoplasm
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 28, 2017 Category: Hematology Authors: Alireza Salem, Sanam Loghavi, Guilin Tang, Yang O. Huh, Elias J. Jabbour, Hagop Kantarjian, Wei Wang, Shimin Hu, Rajyalakshmi Luthra, L. Jeffrey Medeiros, Joseph D. Khoury Tags: Research Article Source Type: research

Utility of factor VIII and factor VIII to von Willebrand factor ratio in identifying 277 unselected carriers of hemophilia A
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 28, 2017 Category: Hematology Authors: Veerle Labarque, Vanitha Perinparajah, Vanessa Bouskill, Ann Marie Stain, Cindy Wakefield, Cecilia Manuel, Victor S. Blanchette, Paula D. James, David Lillicrap, Manuel D. Carcao Tags: Correspondence Source Type: research

Pregnancy in β‐thalassemia intermedia at two tertiary care centers in Lebanon and Italy: A follow‐up report on fetal and maternal outcomes
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 28, 2017 Category: Hematology Authors: Joseph E. Roumi, Hassan M. Moukhadder, Giovanna Graziadei, Martina Pennisi, Maria Domenica Cappellini, Ali T. Taher Tags: Correspondence Source Type: research

A Centrocyte Blood Count of a Quarter Million
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 28, 2017 Category: Hematology Authors: Matthew Behrens, Rajasree P. Chowdry, Saliba Saba, Nakhle S. Saba Tags: Images in Hematology Source Type: research

BCL2 mutations do not confer adverse prognosis in follicular lymphoma patients treated with rituximab
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 28, 2017 Category: Hematology Authors: Sarah Huet, Edith Szafer ‐Glusman, Bruno Tesson, Luc Xerri, Wayne J. Fairbrother, Kiran Mukhyala, Chris Bolen, Elizabeth Punnoose, Laurie Tonon, Catherine Chassagne‐Clément, Pierre Feugier, Alain Viari, Fabrice Jardin, Gilles Salles, Pierre Sujobert Tags: Research Article Source Type: research

Desiderosmia (olfactory craving): A novel symptom associated with iron deficiency anemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 27, 2017 Category: Hematology Authors: Bryar R. Hansen, Wayne A. Bottner, Aishwarya Ravindran, Ramona DeJesus, Ronald S. Go Tags: Correspondence Source Type: research

Mutations of RUNX1 in families with inherited thrombocytopenia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 26, 2017 Category: Hematology Authors: Daniela De Rocco, Federica Melazzini, Caterina Marconi, Alessandro Pecci, Roberta Bottega, Chiara Gnan, Flavia Palombo, Paola Giordano, Maria Susanna Coccioli, Ana C. Glembotsky, Paula G. Heller, Marco Seri, Anna Savoia, Patrizia Noris Tags: Correspondence Source Type: research

Newly diagnosed immune thrombocytopenia adults: clinical epidemiology, exposure to treatments and evolution. Results of the CARMEN multicenter prospective cohort
In conclusion, severe bleeding is rare at ITP onset. Associated autoimmune diseases and recent infections were frequent. Antinuclear antibodies seem predictors of chronicity. Intravenous corticosteroids and IVIg were frequently used. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 26, 2017 Category: Hematology Authors: Guillaume Moulis, Johanne Germain, Thibault Comont, Natacha Brun, Claire Dingremont, Brice Castel, Sophie Arista, Laurent Sailler, Maryse Lapeyre ‐Mestre, Odile Beyne‐Rauzy, Bertrand Godeau, Daniel Adoue, Tags: Research Article Source Type: research

Therapy Induced Iron Deficiency in Children Treated with Eltrombopag for Immune Thrombocytopenia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 26, 2017 Category: Hematology Authors: Michele P. Lambert, Char M. Witmer, Janet L. Kwiatkowski Tags: Correspondence Source Type: research

Predicting Risk Of Venous Thromboembolism In Hospitalized Cancer Patients: Utility of A Risk Assessment Tool
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 26, 2017 Category: Hematology Authors: Rushad Patell, Lisa Rybicki, Keith R. McCrae, Alok A. Khorana Tags: Research Article Source Type: research

The Reliability of Six Prognostic Models to Predict Time ‐to‐First‐ Treatment in Patients with Chronic Lymphocytic Leukaemia in Early Phase
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 26, 2017 Category: Hematology Authors: Stefano Molica, Diana Giannarelli, Rosanna Mirabelli, Luciano Levato, Massimo Gentile, Fortunato Morabito, Emili Montserrat Tags: Correspondence Source Type: research

Autoimmune hemolytic anemia in a young man with acute hepatitis E infection
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 23, 2017 Category: Hematology Authors: Rebecca Karp Leaf, Kerry L. O'Brien, David E. Leaf, Reed E. Drews Tags: Correspondence Source Type: research

Plasmodium knowlesi
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 22, 2017 Category: Hematology Authors: Peter Chiodini, Barbara J. Bain Tags: Morphology Update Source Type: research

Evaluation of the efficiency of hydroxychloroquine in treating children with immune thrombocytopenia (ITP)
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 22, 2017 Category: Hematology Authors: Ombeline Roche, Nathalie Aladjidi, Josu é Rakotonjanahary, Guy Leverger, Thierry Leblanc, Caroline Thomas, Marlène Pasquet, Mary‐France Courcoux, Sophie Bayart, Marion Gilibert‐Yvert, Bénédicte Neven, Pierre Quartier, Isabelle Pellier Tags: Correspondence Source Type: research

Gemcitabine and docetaxel as a novel treatment regimen for blastic plasmacytoid dendritic cell neoplasm
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 22, 2017 Category: Hematology Authors: Matthew L. Ulrickson, Akshjot Puri, Sarah Lindstrom, Ryan D. Cassaday, Nicolas De Padova, Pamela S. Becker Tags: Correspondence Source Type: research

Identification of renal infiltration based on urinary findings in a child with burkitt leukemia/lymphoma
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 21, 2017 Category: Hematology Authors: Z ühre Kaya, Nurettin Alıcı, Özlem Ezgi Özmen, Meltem Akgül, Büşra Topuz, Emine Akkuzu Tags: Images in Hematology Source Type: research

Publication Outcomes of Abstracts from the American Society of Hematology Annual Meeting
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 21, 2017 Category: Hematology Authors: Sujatha Baddam, Gary R. Cutter, Julie A. Wolfson, Gregory K. Friedman, Jeffrey D. Lebensburger Tags: Correspondence Source Type: research

In vivo confocal microscopy of multiple myeloma associated crystalline keratopathy
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 21, 2017 Category: Hematology Authors: Caleb Busch, Shizuka Koh, Yoshinori Oie, Michiko Ichii, Yuzuru Kanakura, Kohji Nishida Tags: Diagnostic Imaging in Hematology Source Type: research

Retraction: ‘Number needed to treat with 4‐factor prothrombin complex concentrate for urgent warfarin reversal’ by Andrew Chua, Vishal Patel, Allison Perrin, Lee Stern, Jenifer Ehreth, Laurel Omert, Christopher Hood, Julie Farley, Michael McGlynn and Liping Huang
Abstract The above abstract from the THSNA 2016 Summit Abstract Proceedings, first published online in the American Journal of Hematology on 20 July 2016 in Wiley OnlineLibrary (www.onlinelibrary.wiley.com), and in Volume 91, Issue 9, p. E427, has been retracted by agreement between the authors, the journal Editor‐in‐Chief, Carlo Brugnara, and Wiley Periodicals, Inc. The retraction has been agreed due to concerns from the submitting authors that the abstract was inadvertently submitted prior to receiving approval from all authors and proper review of data analytics, thereby rendering it incomplete. ReferenceTHSNA 2016 ...
Source: American Journal of Hematology - February 20, 2017 Category: Hematology Tags: RETRACTION Source Type: research

Varicella ‐Zoster Virus Meningoencephalitis in a Patient Treated with Ruxolitinib
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 18, 2017 Category: Hematology Authors: Ophir Eyal, Maayan Flaschner, Arie Ben Yehuda, Deborah Rund Tags: Correspondence Source Type: research

A phase 2 safety study of accelerated elotuzumab infusion, over less than 1 hour, in combination with lenalidomide and dexamethasone, in patients with multiple myeloma
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 17, 2017 Category: Hematology Authors: James Berenson, Robert Manges, Suprith Badarinath, Alan Cartmell, Kristi McIntyre, Roger Lyons, Wael Harb, Hesham Mohamed, Ali Nourbakhsh, Robert Rifkin Tags: Research Article Source Type: research

Concomitant monitoring of WT1 and FLT3 ‐ITD expression in FLT3‐ITD Acute Myeloid Leukemia patients: which should we trust as a minimal residual disease marker?
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 17, 2017 Category: Hematology Authors: Federico De Marchi, Anna Candoni, Maria Elena Zannier, Wing Yin Bonnie Lau, Lisa Haley, Renato Fanin Tags: Correspondence Source Type: research

The prognostic relevance of serum lactate dehydrogenase and mild bone marrow reticulin fibrosis in essential thrombocythemia
Abstract The 2016 World Health Organization (WHO) diagnostic criteria for myeloproliferative neoplasms (MPN) underscore the prognostically‐relevant distinction between essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre‐PMF). In addition, leukocytosis has been identified as an important prognostic marker in otherwise WHO‐defined ET. However, controversy remains regarding the objectivity of morphologic criteria in distinguishing ET from pre‐PMF and the precise prognostic cutoff values for leukocytosis. Serum lactate dehydrogenase (LDH) level might be a biologically more accurate measure of leuk...
Source: American Journal of Hematology - February 16, 2017 Category: Hematology Authors: Mythri Mudireddy, Daniela Barraco, Curtis A. Hanson, Animesh Pardanani, Naseema Gangat, Ayalew Tefferi Tags: Research Article Source Type: research

DAT ‐positive Plasmodium ovale malaria presenting in a child with sickle cell anemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 16, 2017 Category: Hematology Authors: Nicholas S. Whipple, Jason R. Schwartz, Kerri A. Nottage Tags: Images in Hematology Source Type: research

Lifespan care in SCD: Whom to transition, the patients or the health care system?
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 16, 2017 Category: Hematology Authors: Caterina P. Minniti, Elliott Vichinsky Tags: Commentary Source Type: research

Diagnostic impact of the 2016 revised WHO criteria for polycythemia vera
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 15, 2017 Category: Hematology Authors: Tiziano Barbui, Juergen Thiele, Heinz Gisslinger, Alessandra Carobbio, Alessandro M Vannucchi, Ayalew Tefferi Tags: Commentary Source Type: research

Prognostic Significance of Cytogenetic Abnormalities in T ‐Cell Prolymphocytic Leukemia
In this study, we correlated cytogenetic abnormalities with clinical outcome in 97 T‐PLL patients, including 66 men and 31 women with a median age of 63 years (range, 34‐81). Twenty‐seven patients had a normal karyotype (NK), one had two chromosomal aberrations, and 69 had a complex karyotype (CK). Patients with a CK had poorer overall survival (OS) than patients with a NK (P=0.0016). In the CK group, the most common aberrations involved 14q (n=45) and 8q (n=38). Additional deletions of chromosomes 17p, 11q, 6q, 12p, 13q were observed frequently. No individual cytogenetic abnormality impacted OS. Patients with ≥5 ...
Source: American Journal of Hematology - February 14, 2017 Category: Hematology Authors: Zhihong Hu, L. Jeffrey Medeiros, Lianghua Fang, Yi Sun, Zhenya Tang, Guilin Tang, Tsieh Sun, Andres E. Quesada, Shimin Hu, Sa A. Wang, Lin Pei, Xinyan Lu Tags: Research Article Source Type: research

Association of immune globulin intravenous and thromboembolic adverse events
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 12, 2017 Category: Hematology Authors: Mikhail V. Ovanesov, Mikhail D. Menis, Dorothy E. Scott, Richard Forshee, Steven Anderson, Wilson Bryan, Basil Golding Tags: CORRESPONDENCE Source Type: research

Impact of fludarabine ‐based induction therapy on outcome of FLT3−/NPM1+ cytogenetically normal acute myeloid leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 12, 2017 Category: Hematology Authors: Mario Tiribelli, Antonella Geromin, Daniela Damiani Tags: CORRESPONDENCE Source Type: research

Low affinity hemoglobinopathy (Hb Vigo) due to a new mutation of beta globin gene (c200 A > T; Lys > Ile). A cause of rare anemia misdiagnosis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 12, 2017 Category: Hematology Authors: Mar ía del Mar Mañú Pereira, Paloma Ropero, Carmen Loureiro, Joan‐Lluis Vives Corrons Tags: CORRESPONDENCE Source Type: research

A higher prevalence of hematologic malignancies in patients with thalassemia: background and culprits
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 12, 2017 Category: Hematology Authors: Racha Halawi, Domenica Cappellini, Ali Taher Tags: Commentary Source Type: research

Hematologic malignancies in thalassemia: Adding new cases to the repertoire
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 12, 2017 Category: Hematology Authors: Racha Halawi, Hassan Beydoun, M. Domenica Cappellini, Valeria Ferla, Ali Taher Tags: Correspondence Source Type: research

A Patient with Both Methemoglobinemia and G6PD Deficiency: A Therapeutic Conundrum
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 12, 2017 Category: Hematology Authors: N. Scott Reading, Jos é A. Ruiz‐Bonilla, Robert D. Christensen, William Cáceres‐Perkins, Josef T. Prchal Tags: Solving Clinical Problems in Blood Diseases Source Type: research

Refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis (RARS ‐T): 2017 update on diagnosis, risk‐stratification, and management
Abstract Disease OverviewRing sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. Two myeloid neoplasms defined by the presence of RS, include refractory anemia with ring sideroblasts (RARS), now classified under myelodysplastic syndromes with RS (MDS‐RS) and RARS with thrombocytosis (RARS‐T); now called myelodysplastic/myeloproliferative neoplasm with RS and thrombocytosis (MDS/MPN‐RS‐T). DiagnosisMDS‐RS is a lower risk MDS, with single or multilineage dysplasia (SLD/MLD),
Source: American Journal of Hematology - February 10, 2017 Category: Hematology Authors: Mrinal M. Patnaik, Ayalew Tefferi Tags: Annual Clinical Updates in Hematological Malignancies: A Continuing Medical Education Series Source Type: research

Issue Information – Table of Contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 10, 2017 Category: Hematology Tags: Issue Information – Table of Contents Source Type: research

Allogeneic NK cells eradicate myeloblasts but not neoplastic mast cells in systemic mastocytosis associated with acute myeloid leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 9, 2017 Category: Hematology Authors: Celalettin Ustun, Sarah Williams, Sasha Skendzel, Behiye Kodal, Michel Arock, Jason Gotlib, Daniel Vallera, Sarah Cooley, Martin Felices, Daniel Weisdorf, Jeffrey Miller Tags: Correspondence Source Type: research

Validation of the Acute Leukemia ‐EBMT score for prediction of mortality following allogeneic stem cell transplantation in a multi‐center GITMO cohort
In conclusion, the AL‐EBMT score identified 3 distinct risk groups and was predictive of OS. It is a valid tool for stratifying the risk of acute leukemia patients undergoing allogeneic HSCT. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - February 8, 2017 Category: Hematology Authors: Roni Shouval, Francesca Bonifazi, Joshua Fein, Cristina Boschini, Elena Oldani, Myriam Labopin, Roberto Raimondi, Nicoletta Sacchi, Osamah Dabash, Ron Unger, Mohamad Mohty, Alessandro Rambaldi, Arnon Nagler Tags: Research Article Source Type: research

Orbital cellulitis as the initial presentation of Langerhans Cell Histiocytosis in an adult patient
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 8, 2017 Category: Hematology Authors: Avash Das, Arjun Gupta, Harris VK Naina Tags: Images in Hematology Source Type: research

Identification of targeted therapies for rare adult mature t ‐cell leukemia using functional ex vivo screening of primary patient samples
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 8, 2017 Category: Hematology Authors: Uma Borate, Brianna A. Norris, Pierrette Lo, Cristina Tognon, Jeffrey Tyner, Stephen Spurgeon Tags: Correspondence Source Type: research

PET ‐positive lymphadenopathy in CLL—Not always Richter transformation
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 6, 2017 Category: Hematology Authors: Naveen Pemmaraju, Preetesh Jain, L. Jeffrey Medeiros, Jeffrey L. Jorgenson, Nitin Jain, Jason Willis, Dimitrios P. Kontoyiannis, Zeev Estrov, William G. Wierda Tags: Images in Hematology Source Type: research

Howell –Jolly bodies in acute hemolytic anemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 6, 2017 Category: Hematology Authors: Barbara J. Bain Tags: MORPHOLOGY UPDATE Source Type: research

2017 Clinical trials update: Innovations in hemophilia therapy
(Source: American Journal of Hematology)
Source: American Journal of Hematology - February 6, 2017 Category: Hematology Tags: Erratum Source Type: research

Clinical utility of closure times using the platelet function analyzer ‐100/200
The “platelet function analyzer” (PFA)−100 was first introduced to us in 1995. Since then, the instrument has appeared in over 50 reviews and almost 1000 publications. Recently, the PFA‐100 has been “upgraded” to the PFA‐200, which has transformed the user interface and electronic management, but retained the fundamental mechanics, and essentially provides the same results. The PFA‐100/200 has conceivable clinical utility to screen for von Willebrand Disease (VWD) and platelet disorders, and in monitoring desmopressin (DDAVP) therapy in both, and possibly anti‐platelet therapy. Its gre...
Source: American Journal of Hematology - February 6, 2017 Category: Hematology Authors: Emmanuel J. Favaloro Tags: TEST OF THE MONTH Source Type: research

K. Pneumoniae liver abscess following deferoxamine subcutaneous self ‐injection
(Source: American Journal of Hematology)
Source: American Journal of Hematology - January 31, 2017 Category: Hematology Authors: Ludovico Furlan, Giovanna Graziadei, Giulia Colombo, Laura Virginia Forzenigo, Monica Solbiati Tags: Diagnostic Imaging in Hematology Source Type: research