Issue Information – Table of Contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 17, 2017 Category: Hematology Tags: ISSUE INFORMATION – TABLE OF CONTENTS Source Type: research

Lymphoplasmacytoid cytology in plasma cell leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 13, 2017 Category: Hematology Authors: Ahmad Khoder, Magda Al Obaidi, Natasha Wiles, Elisabet Nadal ‐Melsio, Barbara J. Bain Tags: Morphology Update Source Type: research

The athlete's hematological response to hypoxia: A meta ‐analysis on the influence of altitude exposure on key biomarkers of erythropoiesis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 13, 2017 Category: Hematology Authors: Louisa M. Lobigs, Ken Sharpe, Laura A. Garvican ‐Lewis, Christopher J. Gore, Peter Peeling, Brian Dawson, Yorck O. Schumacher Tags: Research Article Source Type: research

Revisiting the need for bone marrow examination in chronic myeloid leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 13, 2017 Category: Hematology Authors: Ayalew Tefferi, Curtis A. Hanson, Rhett P. Ketterling Tags: Commentary Source Type: research

Therapy Related ‐Chronic Myelomonocytic Leukemia (CMML): Molecular, Cytogenetic and Clinical Distinctions from de novo CMML
Abstract Therapy related myeloid neoplasms (t‐MN) including therapy related myelodysplastic syndromes (t‐MDS) and acute myeloid leukemia (t‐AML) are associated with aggressive disease biologies and poor outcomes. In this large (n=497) and informative (inclusive of molecular and cytogenetic information) chronic myelomonocytic leukemia (CMML) patient cohort, we demonstrate key biological insights and an independent prognostic impact for t‐CMML. T‐CMML was diagnosed in 9% of patients and occurred approximately 7 years after exposure to prior chemotherapy and/or radiation therapy. In comparison to de novo CMML, t‐C...
Source: American Journal of Hematology - October 11, 2017 Category: Hematology Authors: Mrinal M. Patnaik, Rangit Vallapureddy, Fevzi F. Yalniz, Curtis A. Hanson, Rhett P. Ketterling, Terra L Lasho, Christy Finke, Aref Al ‐Kali, Naseema Gangat, Ayalew Tefferi Tags: Research Article Source Type: research

Clinical management of peripherally inserted central catheters compared to conventional central venous catheters in patients with hematological malignancies: A large multicenter study of the REL GROUP (Rete Ematologica Lombarda ‐ Lombardy Hematologic Network, Italy)
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 10, 2017 Category: Hematology Authors: Nicola Stefano Fracchiolla, Elisabetta Todisco, Andrea Bilancia, Sara Gandolfi, Nicola Orofino, Francesca Guidotti, Valentina Mancini, Laura Marbello, Andrea Assanelli, Massimo Bernardi, Armando Santoro, Roberto Cairoli, Dario Consonni, Agostino Cortelezz Tags: CORRESPONDENCE Source Type: research

Correcting the cut ‐off point of hemoglobin at high altitude favors misclassification of anemia, erythrocytosis and excessive erythrocytosis
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: Gustavo F. Gonzales, Ver ónica Rubín de Celis, José Begazo, María del Rosario Hinojosa, Sandra Yucra, Alisson Zevallos, Vilma Tapia Tags: Correspondence Source Type: research

Transformation of MDS/MPN ‐RS‐T to AML – Trisomy 13, Resistant Thrombocytosis and Transient Disease Control with Oral Busulfan Therapy
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: A. Barrett, M. Catherwood, P. Thornton, P. Murphy, J. Quinn Tags: Correspondence Source Type: research

Improved prognosis with additional medium ‐dose VP16 to CY/TBI in allogeneic transplantation for high risk ALL in adults
This study was the first to reveal the efficacy of the addition of medium‐dose VP16 to CY/TBI in high‐risk ALL. To establish new myeloablative conditioning regimens including VP16, a large‐scale prospective study is necessary. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: Yasuyuki Arai, Tadakazu Kondo, Akio Shigematsu, Junji Tanaka, Kazuteru Ohashi, Takahiro Fukuda, Michihiro Hidaka, Naoki Kobayashi, Koji Iwato, Toru Sakura, Makoto Onizuka, Yukiyasu Ozawa, Tetsuya Eto, Mineo Kurokawa, Kaoru Kahata, Naoyuki Uchida, Yoshiko Tags: Research Article Source Type: research

Alternate use of thrombopoietin receptor agonists in adult primary immune thrombocytopenia patients: A retrospective collaborative survey from italian hematology centers
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 6, 2017 Category: Hematology Authors: Silvia Cantoni, Monica Carpenedo, Maria Gabriella Mazzucconi, Valerio De Stefano, Valentina Carrai, Marco Ruggeri, Giorgina Specchia, Nicola Vianelli, Fabrizio Pane, Ugo Consoli, Andrea Artoni, Francesco Zaja, Mariella D'Adda, Andrea Visentin, Felicetto F Tags: Research Article Source Type: research

Relatively favourable outcome after allogeneic stem cell transplantation for BCR ‐ABL1‐positive AML: A survey from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT)
Abstract The aim of the study was to assess the role of allogeneic stem cell transplantation (SCT) in patients diagnosed with BCR‐ABL1‐positive acute myeloid leukemia (AML). Fifty‐seven patients (median age, 48 years, range: 19‐67) with BCR‐ABL1 positive AML undergoing SCT were identified. The majority of the patients (70%) received a TKI before the transplant. At SCT 48 patients were in CR (45 in CR1), while 9 patients were transplanted in a more advanced stage of the disease. MRD was negative (BCR‐ABL1/ABL
Source: American Journal of Hematology - October 3, 2017 Category: Hematology Authors: Vladimir Lj Lazarevic, Myriam Labopin, Depei Wu, Ibrahim Yakoub ‐Agha, Anne Huynh, Per Ljungman, Nicolaas Schaap, Jan J. Cornelissen, Natacha Maillard, Pietro Pioltelli, Tobias Gedde‐Dahl, Stig Lenhoff, Mohamed Houhou, Jordi Esteve, Mohamad Mohty, Arn Tags: Research Article Source Type: research

Vanin 1 (VNN1) levels predict poor outcome in acute myeloid leukemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 3, 2017 Category: Hematology Authors: Valerio Izzi, Juho Lakkala, Raman Devarajan, Eeva ‐Riitta Savolainen, Pirjo Koistinen, Ritva Heljasvaara, Taina Pihlajaniemi Tags: Correspondence Source Type: research

Hereditary Stomatocytosis: An underdiagnosed condition
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 3, 2017 Category: Hematology Authors: Immacolata Andolfo, Roberta Russo, Antonella Gambale, Achille Iolascon Tags: Critical Review Source Type: research

High dose chemotherapy and autologous stem cell transplantation in nodular lymphocyte ‐predominant Hodgkin lymphoma: A retrospective study by the European Society for Blood and Marrow Transplantation (EBMT)‐Lymphoma Working Party
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 3, 2017 Category: Hematology Authors: Saad Akhtar, Silvia Montoto, Ariane Boumendil, Herve Finel, Tamas Masszi, Pavel Jindra, Damir Nemet, Stephan Fuhrmann, Yves Beguin, Luca Castagna, Felicetto Ferrara, Saveria Capria, Ram Malladi, Jose Maria Moraleda, Adrian Bloor, Herv é Ghesquières, Jul Tags: Research Article Source Type: research

Current paradigms in the management of Philadelphia chromosome positive acute lymphoblastic leukemia in adults
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 3, 2017 Category: Hematology Authors: Riad El Fakih, Elias Jabbour, Farhad Ravandi, Mona Hassanein, Farhan Anjum, Syed Ahmed, Hagop Kantarjian Tags: Critical Review Source Type: research

Cardiovascular Evaluation and Management of Iron Overload Cardiomyopathy in Sickle Cell Disease
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 3, 2017 Category: Hematology Authors: Mahazarin Ginwalla, Abdullah AlMasoud, David Tofovic, Tara Alin, Sadeer Al ‐Kindi, Guilherme Oliveira, Sanjay Rajagopalan, Robert Schilz, Jane Little Tags: Correspondence Source Type: research

Severe Thrombocytopenia in a Patient Following Liver Transplantation Caused by HPA ‐1a Antibodies Produced by the Liver Donor
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 1, 2017 Category: Hematology Authors: Paul F. Lindholm, Hau C. Kwaan, Glenn Ramsey, Brian R. Curtis, Jonathan Fryer Tags: Solving Clinical Problems in Blood Diseases Source Type: research

Prognostic significance of additional chromosomal abnormalities at the time of diagnosis in patients with chronic myeloid leukemia treated with frontline tyrosine kinase inhibitors
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - October 1, 2017 Category: Hematology Authors: Ahmad Alhuraiji, Hagop Kantarjian, Prajwal Boddu, Farhad Ravandi, Gautam Borthakur, Courtney DiNardo, Naval Daver, Tapan Kadia, Naveen Pemmaraju, Sherry Pierce, Guillermo Garcia ‐Manero, William Wierda, Srdan Verstovsek, Elias Jabbour, Jorge Cortes Tags: Research Article Source Type: research

Program Expansion of a Day Hospital Dedicated to Manage Sickle Cell Pain
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 1, 2017 Category: Hematology Authors: Jin Han, Santosh L. Saraf, Laura Kavoliunaite, Shivi Jain, Johara Hassan, Lewis L Hsu, Robert E. Molokie, Victor R. Gordeuk, Michel Gowhari Tags: Correspondence Source Type: research

Impact of screening and exclusion of high anti ‐A titer donors on the risk of hemolytic anemia with intravenous immunoglobulin treatment – a hospital‐based cohort study in the US
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 1, 2017 Category: Hematology Authors: Carlos Martinez, Douglas J Watson, Amgad Shebl, Christopher Wallenhorst, Alphonse Hubsch, Toby L Simon Tags: Correspondence Source Type: research

Revised Prevalence Estimate of Possible Hereditary Xerocytosis as Derived from a Large U.S. Laboratory Database
(Source: American Journal of Hematology)
Source: American Journal of Hematology - October 1, 2017 Category: Hematology Authors: Harvey W. Kaufman, Justin K. Niles, Denis R. Gallagher, Alicia Rivera, Seth L. Alper, Carlo Brugnara, L. Michael Snyder Tags: Correspondence Source Type: research

Late infections and secondary malignancies after bendamustine/rituximab or RCHOP/RCVP chemotherapy for B ‐cell lymphomas
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 30, 2017 Category: Hematology Authors: Adam J Olszewski, John L Reagan, Jorge J Castillo Tags: Correspondence Source Type: research

Residual disease detection using targeted parallel sequencing predicts relapse in cytogenetically normal acute myeloid leukemia
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 29, 2017 Category: Hematology Authors: Lukas Gaksch, Karl Kashofer, Ellen Heitzer, Franz Quehenberger, Shruti Daga, Sybille Hofer, Iris Halbwedl, Ricarda Graf, Nina Krisper, Gerald Hoefler, Armin Zebisch, Heinz Sill, Albert W ölfler Tags: Research Article Source Type: research

Urological complications associated with adult allogeneic stem cell transplantation
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 29, 2017 Category: Hematology Authors: Laila Schneidewind, Thomas Neumann, Kathrin Zimmermann, Christian Andreas Schmidt, William Kr üger Tags: Correspondence Source Type: research

Timing and deepness of response to tyrosine kinase inhibitors as a measure of potential treatment discontinuation in chronic myeloid leukemia patients managed in the real ‐life
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 28, 2017 Category: Hematology Authors: Massimo Breccia, Gioia Colafigli, Matteo Molica, Emilia Scalzulli, Daniela Diverio, Roberto Latagliata, Anna Guarini, Robin Fo à Tags: Correspondence Source Type: research

Utility and limitations of exome sequencing in the molecular diagnosis of pediatric inherited platelet disorders
In conclusion, ES has the potential to molecularly diagnose causes of IPD, and to identify candidate genes for functional evaluation. Robust exome sequencing also requires that coverage of genes known to be associated with clinical findings of interest need to be carefully examined and supplemented if necessary. Clinicians who undertake ES should understand the limitations of the test and the full significance of results that may be returned. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 27, 2017 Category: Hematology Authors: Edward J. Romasko, Batsal Devkota, Sawona Biswas, Vijayakumar Jayaraman, Ramakrishnan Rajagopalan, Matthew C. Dulik, Christopher S. Thom, Jiwon Choi, Sowmya Jairam, Maria I. Scarano, Ian D. Krantz, Nancy B. Spinner, Laura K. Conlin, Michele P. Lambert Tags: Research Article Source Type: research

Non ‐invasive monitoring of liver fibrosis in Sickle Cell Disease: Longitudinal observation of a cohort of adult patients
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 27, 2017 Category: Hematology Authors: Valeria Pinto, Barbara Gianesin, Manuela Balocco, Lorenzo Bacigalupo, Gian Luca Forni Tags: Correspondence Source Type: research

Impact of involved free light chain (FLC) levels in patients achieving normal FLC ratio after initial therapy in light chain amyloidosis (AL)
We examined if elevated involved free light chain (hiFLC) impacts outcomes in patients achieving normal FLCr. We retrospectively analyzed 345 AL patients who were diagnosed within a 10‐year period (2006‐2015) and had 2 consecutive normal FLCr values after 1st line treatment. Among these, patients with hiFLC at 1st reading of normal FLCr (hiFLC1; n=166; 48.1%) were compared to those who did not (n=179; 51.9%). Patients with AL who have hiFLC1 after initial therapy had higher rates of multi‐organ involvement (63.3 vs 46.4%; p=0.002) and patients in advanced Mayo stage (42.9 vs 32.2%; p=0.04) at diagnosis. The median pr...
Source: American Journal of Hematology - September 27, 2017 Category: Hematology Authors: Nidhi Tandon, Surbhi Sidana, Angela Dispenzieri, Morie A. Gertz, Martha Q. Lacy, David Dingli, Francis K. Buadi, Amie L. Fonder, Suzanne R. Hayman, Yi Lisa Hwa, Miriam A. Hobbs, Prashant Kapoor, Wilson I. Gonsalves, Nelson Leung, Ronald S. Go, John A. Lus Tags: Research Article Source Type: research

Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6
Abstract Hepcidin is a key iron regulatory hormone that controls expression of the iron exporter ferroportin to increase the iron supply when needed to support erythropoiesis and other essential functions, but to prevent the toxicity of iron excess. The bone morphogenetic protein (BMP)‐SMAD signaling pathway, through the ligand BMP6 and the co‐receptor hemojuvelin, is a central regulator of hepcidin transcription in the liver in response to iron. Here, we show that dietary iron loading has a residual ability to induce Smad signaling and hepcidin expression in Bmp6‐/‐ mice, effects that are blocked by a neutralizing...
Source: American Journal of Hematology - September 25, 2017 Category: Hematology Authors: Susanna Canali, Chia ‐Yu Wang, Kimberly B. Zumbrennen‐Bullough, Abraham Bayer, Jodie L. Babitt Tags: RESEARCH ARTICLE Source Type: research

Clinical outcomes in adult patients with aplastic anemia: A single institution experience
Abstract Newer treatment modalities are being investigated to improve upon historical outcomes with standard immunosuppressive therapy (IST) in aplastic anemia (AA). We analyzed outcomes of adult patients with AA treated with various combinatorial anti‐thymoglobulin‐based IST regimens in frontline and relapsed/refractory (R/R) settings. Pretreatment and on‐treatment clinical characteristics were analyzed for relationships to response and outcome. Among 126 patients reviewed, 95 were treatment‐naïve (TN) and 63, R/R (including 32 from the TN cohort); median ages were 49 and 50 years, respectively. Overall survi...
Source: American Journal of Hematology - September 25, 2017 Category: Hematology Authors: Prajwal Boddu, Guillermo Garcia ‐Manero, Farhad Ravandi, Gautam Borthakur, Elias Jabbour, Courtney DiNardo, Nitin Jain, Naval Daver, Naveen Pemmaraju, Paolo Anderlini, Simrit Parmar, Devendra KC, Mary Akosile, Sherry A. Pierce, Richard Champlin, Jorge C Tags: RESEARCH ARTICLE Source Type: research

Diagnostic value of targeted next ‐generation sequencing (NGS) in suspected hemochromatosis patients with a single copy of the HFE p.Cys282Tyr causative allele
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 22, 2017 Category: Hematology Authors: Kevin Uguen, Virginie Scotet, Chandran Ka, Isabelle Gourlaouen, Carine L'Hostis, Marie ‐Christine Merour, Tania Cuppens, Claude Ferec, Gerald Le Gac Tags: Correspondence Source Type: research

The eutos long ‐term survival score (elts) accurately predicts the risk of death in chronic myeloid leukaemia patients treated outside of clinical trials
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 22, 2017 Category: Hematology Authors: Matteo Molica, Martina Canichella, Danilo Alunni Fegatelli, Gioia Colafigli, Fulvio Massaro, Roberto Latagliata, Robin Fo à, Massimo Breccia Tags: Correspondence Source Type: research

Safety and Pharmacokinetics of the Oral Iron Chelator SP ‐420 in β‐thalassemia
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 22, 2017 Category: Hematology Authors: Ali T Taher, Antoine N Saliba, Kevin H Kuo, Patricia J Giardina, Alan R Cohen, Ellis J Neufeld, Yesim Aydinok, Janet L Kwiatkowski, Brenda I Jeglinski, Keith Pietropaolo, Gregory Berk, Vip Viprakasit Tags: Research Article Source Type: research

Liver Dysfunction in Chronic Lymphocytic Leukemia: Prevalence, Outcomes, and Pathological Findings
Abstract The prevalence of liver dysfunction and its association with outcomes in patients with previously untreated chronic lymphocytic leukemia (CLL) is unknown. Newly diagnosed (
Source: American Journal of Hematology - September 22, 2017 Category: Hematology Authors: Paul J. Hampel, Kari G. Chaffee, Rebecca L. King, Douglas Simonetto, Melissa C. Larson, Sara Achenbach, Timothy G. Call, Wei Ding, Saad S. Kenderian, Jose F. Leis, Asher A. Chanan ‐Khan, Deborah A. Bowen, Michael J. Conte, Susan M. Schwager, Curtis A. H Tags: Research Article Source Type: research

Effects of Pre ‐ and Post‐transplantation Minimal Residual Disease on Outcomes in Pediatric Patients with Acute Myeloid Leukemia Receiving Human Leukocyte Antigen‐matched or Mismatched Related Donor Allografts
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 20, 2017 Category: Hematology Authors: Ying ‐Jun Chang, Xiao‐Su Zhao, Yu Wang, Yan‐Rong Liu, Lan‐Ping Xu, Xiao‐Hui Zhang, Huan Chen, Yu‐Hong Chen, Wei‐ Han, Yu‐Qian Sun, Chen‐Hua Yan, Xiao‐Dong Mo, Kai‐Yan Liu, Xiao‐Jun Huang Tags: Correspondence Source Type: research

Treatment of hepatitis C virus infection with direct ‐acting antiviral drugs is safe and effective in patients with hemoglobinopathies
In conclusion, the use of DAAs appears to be safe and effective in patients with hemoglobinopathies and advanced liver disease due to HCV. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 20, 2017 Category: Hematology Authors: Raffaella Origa, Maria Laura Ponti, Aldo Filosa, Alfonso Galeota Lanza, Antonio Piga, Giorgio Maria Saracco, Valeria Pinto, Antonino Picciotto, Paolo Rigano, Salvatore Madonia, Rosamaria Rosso, Domenico D'Ascola, Maria Domenica Cappellini, Roberta D'Ambro Tags: Research Article Source Type: research

Bone marrow xanthomas associated with hypertriglyceridemia
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 19, 2017 Category: Hematology Authors: Nelson CN Chan, Chak ‐Chung Chan, Natalie PH Chan Tags: Diagnostic Imaging in Hematology Source Type: research

Incidence and predictive score for delayed hemolytic transfusion reaction in adult patients with sickle cell disease
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 19, 2017 Category: Hematology Authors: David Narbey, Anoosha Habibi, Philippe Chadebech, Armand Mekontso ‐Dessap, Mehdi Khellaf, Jean‐Daniel Lelièvre, Bertrand Godeau, Marc Michel, Frédéric Galactéros, Rachid Djoudi, Pablo Bartolucci, France Pirenne Tags: Research Article Source Type: research

A Clinically Meaningful Fetal Hemoglobin Threshold for Children with Sickle Cell Anemia During Hydroxyurea Therapy
Abstract Hydroxyurea has proven clinical benefits and is recommended to be offered to all children with sickle cell anemia (SCA), but the optimal dosing regimen remains controversial. Induction of red blood cell fetal hemoglobin (HbF) by hydroxyurea appears to be dose‐dependent. However, it is unknown whether maximizing HbF% improves clinical outcomes. HUSTLE (NCT00305175) is a prospective observational study with a primary goal of describing the long‐term clinical effects of hydroxyurea escalated to maximal tolerated dose (MTD) in children with SCA. In 230 children, providing 610 patient‐years of follow up, the mean...
Source: American Journal of Hematology - September 15, 2017 Category: Hematology Authors: Jeremie H. Estepp, Matthew P. Smeltzer, Guolian Kang, Chen Li, Winfred C. Wang, Christina Abrams, Banu Aygun, Russell E. Ware, Kerri Nottage, Jane S. Hankins Tags: Research Article Source Type: research

A nationwide survey of hypoplastic myelodysplastic syndrome (a multicenter retrospective study)
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 11, 2017 Category: Hematology Authors: Takashi Kobayashi, Yasuhito Nannya, Motoshi Ichikawa, Kenji Oritani, Yuzuru Kanakura, Akihiro Tomita, Hitoshi Kiyoi, Masayoshi Kobune, Junji Kato, Hiroshi Kawabata, Motohiro Shindo, Yoshihiro Torimoto, Yuji Yonemura, Nobuyoshi Hanaoka, Hideki Nakakuma, Da Tags: Research Article Source Type: research

Clinical management of peripherally ‐inserted central catheters (PICCs) compared to conventional central venous catheters (cCVCs) in patients with hematological malignancies: a large multicenter study of the REL GROUP (Rete Ematologica Lombarda ‐ Lombardy Hematologic Network, Italy)
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 11, 2017 Category: Hematology Authors: Nicola Stefano Fracchiolla, Elisabetta Todisco, Andrea Bilancia, Sara Gandolfi, Nicola Orofino, Francesca Guidotti, Valentina Mancini, Laura Marbello, Andrea Assanelli, Massimo Bernardi, Armando Santoro, Roberto Cairoli, Dario Consonni, Agostino Cortelezz Tags: Correspondence Source Type: research

Unrelated matched versus autologous transplantation in adult patients with good and intermediate risk acute myelogenous leukemia in first molecular remission
Abstract Patients with Acute Myelogenous Leukemia have a better outcome if reaching molecular remission. We compared the outcome of 373 patients autografted and 335 patients allografted with a 10/10 compatible unrelated donor in first molecular remission. Patients were stratified using the ELN European Leukemia Net classification. ELN favorable group: (234 auto and 70 unrelated transplants). By univariate analysis, in the auto group, the Non Relapse Mortality (NRM) was lower (3.7% versus 19%; p
Source: American Journal of Hematology - September 11, 2017 Category: Hematology Authors: Norbert ‐Claude Gorin, Myriam Labopin, Thomas Pabst, Peter Remenyi, Depei Wu, Anne Huynh, Liisa Volin, Jean Yves Cahn, Ibrahim Yakoub‐Agha, Melanie Mercier, Mohamed Houhou, Mohamad Mohty, Arnon Nagler, Tags: Research Article Source Type: research

Identification of novel mutations in the HbF repressor gene BCL11A in patients with autism and intelligence disabilities
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 10, 2017 Category: Hematology Authors: Tao Cai, Xiang Chen, Jinchen Li, Bingwu Xiang, Liu Yang, Yidian Liu, Qiuli Chen, Zhouwen He, Kevin Sun, P. Paul Liu Tags: Correspondence Source Type: research

Diagnosis of thrombotic thrombocytopenic purpura among patients with ADAMTS13 Activity 10% ‐20%
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 8, 2017 Category: Hematology Authors: Adanma Ayanambakkam, Johanna A. Kremer Hovinga, Sara K. Vesely, James N. George Tags: CORRESPONDENCE Source Type: research

Targeted next ‐generation sequencing in myelodysplastic syndromes and prognostic interaction between mutations and IPSS‐R
This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - September 6, 2017 Category: Hematology Authors: Ayalew Tefferi, Terra L Lasho, Mrinal M Patnaik, Lyla Saeed, Mythri Mudireddy, Dame Idossa, Christy Finke, Rhett P Ketterling, Animesh Pardanani, Naseema Gangat Tags: Research Article Source Type: research

Cutaneous T ‐cell lymphoma: 2017 update on diagnosis, risk‐stratification, and management
Abstract Disease overviewCutaneous T‐cell lymphomas are a heterogenous group of T‐cell lymphoproliferative disorders involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS). DiagnosisThe diagnosis of MF or SS requires the integration of clinical and histopathologic data. Risk‐adapted therapyTNMB (tumor, node, metastasis, blood) staging remains the most important prognostic factor in MF/SS and forms the basis for a “risk‐adapted,” multi‐disciplinary approach to treatment. For patients with disease limited to the skin, expectant management or ...
Source: American Journal of Hematology - September 5, 2017 Category: Hematology Authors: Ryan A. Wilcox Tags: ANNUAL CLINICAL UPDATES IN HEMATOLOGICAL MALIGNANCIES Source Type: research

Issue Information – Table of Contents
(Source: American Journal of Hematology)
Source: American Journal of Hematology - September 5, 2017 Category: Hematology Tags: Issue Information – Table of Contents Source Type: research

Causes of Hospital Admission in β‐Thalassemia (CHAT) in Lebanon from 1995 to 2015: A pilot retrospective study from a tertiary care center
(Source: American Journal of Hematology)
Source: American Journal of Hematology - August 31, 2017 Category: Hematology Authors: Antoine N. Saliba, Hassan M. Moukhadder, Afif Harb, Hassan Beydoun, Rayan Bou ‐Fakhredin, Ali T. Taher Tags: Correspondence Source Type: research

Enhancing diversity in the hematology biomedical research workforce: A mentoring program to improve the odds of career success for early stage investigators
(Source: American Journal of Hematology)
Source: American Journal of Hematology - August 31, 2017 Category: Hematology Authors: Betty S. Pace, Levi H. Makala, Rita Sarkar, Li Liu, Mayuko Takezaki, Narla Mohandas, Glorias Dixon, Ellen M. Werner, Donna B. Jeffe, Treva K. Rice, Nita J. Maihle, Juan Gonz ález Tags: Commentary Source Type: research

Long ‐term survival of beta thalassemia major patients treated with hematopoietic stem cell transplantation compared with survival with conventional treatment
In conclusion, the 30‐year survival rate of ex‐thalassemia patients after HSCT was similar to that expected in CT thalassemia patients, with the vast majority of HSCT survivors cured from thalassemia. This article is protected by copyright. All rights reserved. (Source: American Journal of Hematology)
Source: American Journal of Hematology - August 29, 2017 Category: Hematology Authors: Giovanni Caocci, Maria Grazia Orofino, Adriana Vacca, Antonio Piroddi, Eugenia Piras, Maria Carmen Addari, Rossella Caria, Maria Paola Pilia, Raffaella Origa, Paolo Moi, Giorgio La Nasa Tags: Research Article Source Type: research