Effect of low- versus high-dose 4-factor prothrombin complex concentrate in factor Xa inhibitor-associated bleeding: A qualitative systematic review
CONCLUSION: These results suggest low- and high-dose 4F-PPC may confer similar clinical effectiveness and safety; however, these findings should be evaluated and confirmed with future prospective studies.PMID:38430127 | DOI:10.1093/ajhp/zxae009 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 2, 2024 Category: Drugs & Pharmacology Authors: Anna Phillips Colby Bradley Julie Cash Ryan Sangiovanni Charles Wingerson Source Type: research

Communication between healthcare professionals and patients with hearing loss: A systematic review and meta-analysis
CONCLUSION: Communication barriers exist. Qualified sign language interpreters and assistive technology should be used to improve communication.PMID:38430534 | DOI:10.1093/ajhp/zxae045 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 2, 2024 Category: Drugs & Pharmacology Authors: Neeranun Weerapol Nattawut Leelakanok Source Type: research

Maximizing opioid stewardship through fentanyl vial size optimization in an independent hospital
Am J Health Syst Pharm. 2024 Mar 2:zxae030. doi: 10.1093/ajhp/zxae030. Online ahead of print.ABSTRACTIn an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.PMID:38430120 | DOI:10.1093/ajhp/zxae030 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 2, 2024 Category: Drugs & Pharmacology Authors: Tyler Cramer Source Type: research

Effect of low- versus high-dose 4-factor prothrombin complex concentrate in factor Xa inhibitor-associated bleeding: A qualitative systematic review
CONCLUSION: These results suggest low- and high-dose 4F-PPC may confer similar clinical effectiveness and safety; however, these findings should be evaluated and confirmed with future prospective studies.PMID:38430127 | DOI:10.1093/ajhp/zxae009 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 2, 2024 Category: Drugs & Pharmacology Authors: Anna Phillips Colby Bradley Julie Cash Ryan Sangiovanni Charles Wingerson Source Type: research

Communication between healthcare professionals and patients with hearing loss: A systematic review and meta-analysis
CONCLUSION: Communication barriers exist. Qualified sign language interpreters and assistive technology should be used to improve communication.PMID:38430534 | DOI:10.1093/ajhp/zxae045 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 2, 2024 Category: Drugs & Pharmacology Authors: Neeranun Weerapol Nattawut Leelakanok Source Type: research

Comparative effectiveness of sacubitril/valsartan versus angiotensin receptor blockers in patients with heart failure with preserved ejection fraction: A real-world study
CONCLUSION: Among individuals with private or Medicare Advantage insurance plans, there was no significant difference in the risk of HF-related hospitalization or all-cause hospitalization between adults with HFpEF who received SAC/VAL and those who received ARB therapy.PMID:38427969 | DOI:10.1093/ajhp/zxae053 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 1, 2024 Category: Drugs & Pharmacology Authors: Munaza Riaz Steven M Smith Eric A Dietrich David E Winchester Jingchuan Guo Haesuk Park Source Type: research

Comparative effectiveness of sacubitril/valsartan versus angiotensin receptor blockers in patients with heart failure with preserved ejection fraction: A real-world study
CONCLUSION: Among individuals with private or Medicare Advantage insurance plans, there was no significant difference in the risk of HF-related hospitalization or all-cause hospitalization between adults with HFpEF who received SAC/VAL and those who received ARB therapy.PMID:38427969 | DOI:10.1093/ajhp/zxae053 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - March 1, 2024 Category: Drugs & Pharmacology Authors: Munaza Riaz Steven M Smith Eric A Dietrich David E Winchester Jingchuan Guo Haesuk Park Source Type: research

Using name overlap analysis to understand medication name search safety
CONCLUSION: Medication name left-to-right character overlap on lists of names searched ranges widely. Instead of requiring all users to type a set number of characters when searching for medications by name, search safety can potentially be improved by upgrading computer systems to dynamically respond to each keystroke entered. Using incremental dynamic search, searchers would often be able to type fewer than 5 characters to isolate a single medication by name but would sometimes have to type many more than 5 characters to do so.PMID:38400784 | DOI:10.1093/ajhp/zxae048 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 24, 2024 Category: Drugs & Pharmacology Authors: Allen Flynn Katherine D Mieure Conor Myers Source Type: research

Using name overlap analysis to understand medication name search safety
CONCLUSION: Medication name left-to-right character overlap on lists of names searched ranges widely. Instead of requiring all users to type a set number of characters when searching for medications by name, search safety can potentially be improved by upgrading computer systems to dynamically respond to each keystroke entered. Using incremental dynamic search, searchers would often be able to type fewer than 5 characters to isolate a single medication by name but would sometimes have to type many more than 5 characters to do so.PMID:38400784 | DOI:10.1093/ajhp/zxae048 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 24, 2024 Category: Drugs & Pharmacology Authors: Allen Flynn Katherine D Mieure Conor Myers Source Type: research

Using name overlap analysis to understand medication name search safety
CONCLUSION: Medication name left-to-right character overlap on lists of names searched ranges widely. Instead of requiring all users to type a set number of characters when searching for medications by name, search safety can potentially be improved by upgrading computer systems to dynamically respond to each keystroke entered. Using incremental dynamic search, searchers would often be able to type fewer than 5 characters to isolate a single medication by name but would sometimes have to type many more than 5 characters to do so.PMID:38400784 | DOI:10.1093/ajhp/zxae048 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 24, 2024 Category: Drugs & Pharmacology Authors: Allen Flynn Katherine D Mieure Conor Myers Source Type: research

Using name overlap analysis to understand medication name search safety
CONCLUSION: Medication name left-to-right character overlap on lists of names searched ranges widely. Instead of requiring all users to type a set number of characters when searching for medications by name, search safety can potentially be improved by upgrading computer systems to dynamically respond to each keystroke entered. Using incremental dynamic search, searchers would often be able to type fewer than 5 characters to isolate a single medication by name but would sometimes have to type many more than 5 characters to do so.PMID:38400784 | DOI:10.1093/ajhp/zxae048 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 24, 2024 Category: Drugs & Pharmacology Authors: Allen Flynn Katherine D Mieure Conor Myers Source Type: research

Using name overlap analysis to understand medication name search safety
CONCLUSION: Medication name left-to-right character overlap on lists of names searched ranges widely. Instead of requiring all users to type a set number of characters when searching for medications by name, search safety can potentially be improved by upgrading computer systems to dynamically respond to each keystroke entered. Using incremental dynamic search, searchers would often be able to type fewer than 5 characters to isolate a single medication by name but would sometimes have to type many more than 5 characters to do so.PMID:38400784 | DOI:10.1093/ajhp/zxae048 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 24, 2024 Category: Drugs & Pharmacology Authors: Allen Flynn Katherine D Mieure Conor Myers Source Type: research

Managing the unexpected: considerations for new pharmacy leaders
Am J Health Syst Pharm. 2024 Feb 23:zxae029. doi: 10.1093/ajhp/zxae029. Online ahead of print.ABSTRACTIn an effort to expedite the publication of articles, AJHP is posting manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time.PMID:38390912 | DOI:10.1093/ajhp/zxae029 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 23, 2024 Category: Drugs & Pharmacology Authors: Michael J Peters Joelle Hall William M Hammonds James A M Rhodes Tyler A Vest Source Type: research

Evaluating the impact of a pharmacy technician training program within a college of pharmacy
CONCLUSION: A pharmacy technician training program housed within a college of pharmacy presents one potential solution in addressing pharmacy technician workforce shortages. Participants positively viewed their training experience, with high self-efficacy ratings for pharmacy technician competencies. Moreover, national certification exam results were slightly better than national averages.PMID:38391268 | DOI:10.1093/ajhp/zxae052 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 23, 2024 Category: Drugs & Pharmacology Authors: James S Wheeler Nicholas Martin Rachel E Barenie Source Type: research

Pharmacist perspectives on emerging T cell-engaging bispecific therapies in cancer therapeutics
CONCLUSION: Bispecific therapies have continued to evolve the therapeutic landscape of cancer, primarily in hematological malignancies. Health-system pharmacists have the opportunity to play a key role in the operationalization and management of this new and emerging drug class.PMID:38394329 | DOI:10.1093/ajhp/zxae050 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 23, 2024 Category: Drugs & Pharmacology Authors: Donald C Moore Naomi Digiantonio Carolyn J Oxencis Kate D Taucher Source Type: research