American Journal of Clinical Dermatology American Journal of Clinical Dermatology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Review of Laser Treatments for Post-Inflammatory Hyperpigmentation in Skin of Color
AbstractPost-inflammatory hyperpigmentation is an extremely common disorder of pigmentation in skin of color. It most frequently and severely affects phototypes that are rich in melanin and often has a chronic and unpredictable course. It presents significant treatment challenges and often requires a multi-factorial approach. We review the literature available for the optimal use of laser-based devices in the treatment of post-inflammatory hyperpigmentation, particularly for Fitzpatrick skin phototypes III –VI. For the treatment of post-inflammatory hyperpigmentation in skin of color, lasers remain second line to topical...
Source: American Journal of Clinical Dermatology - February 13, 2023 Category: Dermatology Source Type: research

Effects of Exercise and Dietary Modifications on Hidradenitis Suppurativa: A Systematic Review
ConclusionsMore evidence is needed in the form of randomized controlled trials or well-designed controlled trials to evaluate the effect of exercise and dietary manipulation on the hidradenitis suppurativa disease course. Overall, there is significant but weak evidence to support improvement in hidradenitis suppurativa severity with weight loss, dietary changes, and micronutrient supplementation. There is no significant evidence to support improvement in hidradenitis suppurativa symptomology with any type of exercise intervention.Clinical Trial RegistrationThis protocol was registered with PROSPERO with the registration nu...
Source: American Journal of Clinical Dermatology - February 9, 2023 Category: Dermatology Source Type: research

Patient-Reported Outcome Measures and Their Clinical Applications in Dermatology
AbstractWith more disease- and symptom-specific measures available and research pointing to increased usefulness, patient-reported outcome measures (PROMs) can be routinely used in clinical care. PROMs increase efficiency in healthcare, improve the clinician –patient relationship, and increase patient satisfaction with their care. PROMs can be administered before, during, and after clinic visits using paper-and-pencil, mobile phones, tablets, and computers. Herein, we combine available literature with expert views to discuss overcoming barriers and he lping dermatologists incorporate PROMs into routine patient-centered c...
Source: American Journal of Clinical Dermatology - February 1, 2023 Category: Dermatology Source Type: research

Vitiligo Treatments: Review of Current Therapeutic Modalities and JAK Inhibitors
AbstractVitiligo is a chronic autoimmune disease characterized by loss of pigment of the skin, affecting 0.5 –2% of the population worldwide. It can have a significant impact on patients’ quality of life. In recent years, there has been significant progress in our understanding of the pathogenesis of vitiligo. It is believed that vitiligo develops due to a complex combination of genetics, oxidative str ess, inflammation, and environmental triggers. Conventional treatments include camouflage, topical corticosteroids, topical calcineurin inhibitors, oral corticosteroids, phototherapy, and surgical procedures, with the tr...
Source: American Journal of Clinical Dermatology - January 30, 2023 Category: Dermatology Source Type: research

Muir –Torre Syndrome: A Cutaneous Finding Amidst Broader Malignancies
AbstractMuir –Torre syndrome (MTS) is a rare autosomal dominant genetic condition resulting from microsatellite instability which is caused by mutations in DNA mismatch repair genes. This disorder predisposes individuals to skin tumors and visceral malignancies and may be precipitated in immunocompromised or t ransplant patients. MTS requires close cancer surveillance for the patient and family because of the tendency to develop aggressive internal malignancies and sebaceous carcinoma. Immunohistochemistry and or genetic testing can confirm the diagnosis of MTS. This review offers an update to the guideli nes, diagnosis,...
Source: American Journal of Clinical Dermatology - January 25, 2023 Category: Dermatology Source Type: research

Syphilis in Dermatology: Recognition and Management
AbstractThe incidence of syphilis has been increasing in the USA since 2000. Notably, the coronavirus disease 2019 pandemic negatively impacted the public health efforts to contain the spread of sexually transmitted diseases including syphilis and congenital syphilis. Clinical manifestations of syphilis are predominantly mucocutaneous lesions, thus dermatologists are primed to recognize the myriad presentations of this disease. Primary syphilis is classically characterized by a painless transient chancre most often located in the genital area. Secondary syphilis typically manifests clinically as systemic symptoms in additi...
Source: American Journal of Clinical Dermatology - January 23, 2023 Category: Dermatology Source Type: research

Hypertrophic Scars and Keloids: Advances in Treatment and Review of Established Therapies
AbstractHypertrophic scars and keloids can have significant detrimental effects on patients both psychosocially and functionally. A careful identification of patient risk factors and a comprehensive management plan are necessary to optimize outcomes. Patients with a history of dystrophic scarring should avoid unnecessary procedures and enhance the wound-healing process using various preventive strategies. As there is no single, fully efficacious treatment modality, prevention remains the best approach in reducing aberrant scar formation. When prevention therapies fail, keloids have been shown to be respond to a variety of ...
Source: American Journal of Clinical Dermatology - January 20, 2023 Category: Dermatology Source Type: research

Alcohol and Smoking Cessation as Potential Modulators for Smoking-Associated Psoriasis Risk in Postmenopausal Women: The Women ’s Health Initiative
ConclusionsThese findings indicate that alcohol consumption does not modulate smoking-related psoriasis risk. Cigarette smoking, but not alcohol consumption, is an independent risk factor for psoriasis in postmenopausal women. As greater pack-years was associated with a higher risk of psoriasis and smoking cessation was conversely associated with a lower risk of psoriasis for moderate smokers, a greater emphasis on smoking abstinence and cessation counseling may benefit patients who already have other risk factors for psoriasis. (Source: American Journal of Clinical Dermatology)
Source: American Journal of Clinical Dermatology - January 20, 2023 Category: Dermatology Source Type: research