Atavistic Behavior of Macrophages in the Injured Kidney
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00085.2024. Online ahead of print.NO ABSTRACTPMID:38545648 | DOI:10.1152/ajprenal.00085.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Karl A Nath Source Type: research
2024 Carl W. Gottschalk Distinguished Lectureship of the American Physiological Society Renal Section
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00086.2024. Online ahead of print.NO ABSTRACTPMID:38545649 | DOI:10.1152/ajprenal.00086.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Robert A Fenton David H Ellison Source Type: research
< em > MFSD12 < /em > depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis
In conclusion, MFSD12 mRNA depletion reduced cystine levels in both tested models without improvement of the proximal tubular function in the ctns-/- zebrafish embryo. Additionally, the apparent toxicity of higher mfsd12a TB MO concentrations on the zebrafish development, warrants further evaluation.PMID:38545650 | DOI:10.1152/ajprenal.00014.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Tjessa Bondue Laleh Khodaparast Ladan Khodaparast Sara Cairoli Bianca Maria Goffredo Rik Gijsbers Lambertus van den Heuvel Elena Levtchenko Source Type: research
The Calcium-sensing receptor (CaSR) has only a PTH-dependent role in the acute response of renal phosphatetransporters to phosphate intake
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00009.2024. Online ahead of print.ABSTRACTThe kidney controls systemic inorganic phosphate (Pi) levels by adapting reabsorption to Pi intake. Renal Pi reabsorption is mostly mediated by sodium-phosphate cotransporters NaPi-IIa (SLC34A1) and NaPi-IIc (SLC34A3) which are tightly controlled by various hormones including parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23). PTH and FGF23 rise in response to Pi intake and decrease NaPi-IIa and NaPi-IIc brush border membrane abundance enhancing phosphaturia. Phosphaturia and transporter regulation occur ...
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Arezoo Daryadel Catharina J K üng Bet ül Haykir Sibylle Sabrautzki Martin Hrab ě de Angelis Nati Hernando Isabel Rubio-Aliaga Carsten A Wagner Source Type: research
Renal vascular control during normothermia and passive heat stress in healthy younger men and women
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00034.2024. Online ahead of print.ABSTRACTWe tested the hypothesis that the renal vasoconstrictor and vasodilator responses will be greater in younger women compared to men during passive heat stress. Twenty-five healthy adults [12 women (early follicular phase), 13 men] completed two experimental visits, heat stress or normothermic time-control, assigned in a block-randomized crossover design. During heat stress, core temperature was increased by ~0.8°C in the first hour before commencing a 2-min cold pressor test (CPT). Core temperature remained clamped and ...
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Jessica A Freemas Morgan L Worley Mikaela C Gabler Hayden W Hess Curtis S Goss Tyler B Baker Blair D Johnson Christopher L Chapman Zachary J Schlader Source Type: research
Regulation of the water channel Aquaporin-2 by Cullin E3 ubiquitin ligases
In conclusion, CRLs play a vital role in mediating some of the effects of VP to increase AQP2 plasma membrane accumulation and AQP2 abundance. Whether modulation of cullin activity can contribute to body water homeostasis requires further studies.PMID:38545647 | DOI:10.1152/ajprenal.00049.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Sathish K Murali James A McCormick Robert A Fenton Source Type: research
Atavistic Behavior of Macrophages in the Injured Kidney
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00085.2024. Online ahead of print.NO ABSTRACTPMID:38545648 | DOI:10.1152/ajprenal.00085.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Karl A Nath Source Type: research
2024 Carl W. Gottschalk Distinguished Lectureship of the American Physiological Society Renal Section
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00086.2024. Online ahead of print.NO ABSTRACTPMID:38545649 | DOI:10.1152/ajprenal.00086.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Robert A Fenton David H Ellison Source Type: research
< em > MFSD12 < /em > depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis
In conclusion, MFSD12 mRNA depletion reduced cystine levels in both tested models without improvement of the proximal tubular function in the ctns-/- zebrafish embryo. Additionally, the apparent toxicity of higher mfsd12a TB MO concentrations on the zebrafish development, warrants further evaluation.PMID:38545650 | DOI:10.1152/ajprenal.00014.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Tjessa Bondue Laleh Khodaparast Ladan Khodaparast Sara Cairoli Bianca Maria Goffredo Rik Gijsbers Lambertus van den Heuvel Elena Levtchenko Source Type: research
The Calcium-sensing receptor (CaSR) has only a PTH-dependent role in the acute response of renal phosphatetransporters to phosphate intake
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00009.2024. Online ahead of print.ABSTRACTThe kidney controls systemic inorganic phosphate (Pi) levels by adapting reabsorption to Pi intake. Renal Pi reabsorption is mostly mediated by sodium-phosphate cotransporters NaPi-IIa (SLC34A1) and NaPi-IIc (SLC34A3) which are tightly controlled by various hormones including parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23). PTH and FGF23 rise in response to Pi intake and decrease NaPi-IIa and NaPi-IIc brush border membrane abundance enhancing phosphaturia. Phosphaturia and transporter regulation occur ...
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Arezoo Daryadel Catharina J K üng Bet ül Haykir Sibylle Sabrautzki Martin Hrab ě de Angelis Nati Hernando Isabel Rubio-Aliaga Carsten A Wagner Source Type: research
Renal vascular control during normothermia and passive heat stress in healthy younger men and women
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00034.2024. Online ahead of print.ABSTRACTWe tested the hypothesis that the renal vasoconstrictor and vasodilator responses will be greater in younger women compared to men during passive heat stress. Twenty-five healthy adults [12 women (early follicular phase), 13 men] completed two experimental visits, heat stress or normothermic time-control, assigned in a block-randomized crossover design. During heat stress, core temperature was increased by ~0.8°C in the first hour before commencing a 2-min cold pressor test (CPT). Core temperature remained clamped and ...
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Jessica A Freemas Morgan L Worley Mikaela C Gabler Hayden W Hess Curtis S Goss Tyler B Baker Blair D Johnson Christopher L Chapman Zachary J Schlader Source Type: research
Regulation of the water channel Aquaporin-2 by Cullin E3 ubiquitin ligases
In conclusion, CRLs play a vital role in mediating some of the effects of VP to increase AQP2 plasma membrane accumulation and AQP2 abundance. Whether modulation of cullin activity can contribute to body water homeostasis requires further studies.PMID:38545647 | DOI:10.1152/ajprenal.00049.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Sathish K Murali James A McCormick Robert A Fenton Source Type: research
Atavistic Behavior of Macrophages in the Injured Kidney
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00085.2024. Online ahead of print.NO ABSTRACTPMID:38545648 | DOI:10.1152/ajprenal.00085.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Karl A Nath Source Type: research
2024 Carl W. Gottschalk Distinguished Lectureship of the American Physiological Society Renal Section
Am J Physiol Renal Physiol. 2024 Mar 28. doi: 10.1152/ajprenal.00086.2024. Online ahead of print.NO ABSTRACTPMID:38545649 | DOI:10.1152/ajprenal.00086.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Robert A Fenton David H Ellison Source Type: research
< em > MFSD12 < /em > depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis
In conclusion, MFSD12 mRNA depletion reduced cystine levels in both tested models without improvement of the proximal tubular function in the ctns-/- zebrafish embryo. Additionally, the apparent toxicity of higher mfsd12a TB MO concentrations on the zebrafish development, warrants further evaluation.PMID:38545650 | DOI:10.1152/ajprenal.00014.2024 (Source: Am J Physiol Renal P...)
Source: Am J Physiol Renal P... - March 28, 2024 Category: Urology & Nephrology Authors: Tjessa Bondue Laleh Khodaparast Ladan Khodaparast Sara Cairoli Bianca Maria Goffredo Rik Gijsbers Lambertus van den Heuvel Elena Levtchenko Source Type: research
