The Mechanism of miR-29 in Bladder Cancer Released by Exosomes into Brain Microglia to Promote M2 Polarization and Angiogenesis in Brain Metastasis of Bladder Cancer
CONCLUSION: miR-29 can regulate PI3K/AMPK/PGC-1α/PPAR-γ signaling in microglial cells, promote their polarization to M2, and ultimately promote neovascularization in bladder cancer.PMID:38518156 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Haopeng Tan Yongzhao Li Jianhua Li Kun Wang Yongqiang Xiao Source Type: research

The Effectiveness of Low-dose Esmketamine Versus Remifentanil Adjunct to Propofol for Sedation in Patients Undergoing Radiofrequency Thermocoagulation for Trigeminal Neuralgia
CONCLUSIONS: Low-dose esketamine reduces the total amount of propofol necessary for sedation and incidence of respiratory depression during RFT of gasserian ganglion in American Society of Anesthesiologists I to III patients without affecting recovery time, satisfaction of surgeons and patients, cardiovascular adverse events, when compared with remifentanil.PMID:38518157 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: An Xie Jia Han Feng Ju Yukai Zhou Dan Wu Xianjie Zhang Source Type: research

Research Status and Progress of Studies on Optic Disc Structures in Non-arteritic Anterior Ischemic Optic Neuropathy
CONCLUSION: The risk factors of NAION include systemic factors such as hypertension, diabetes, and nocturnal hypotension and local factors such as small optic cup, crowded optic discs, ODD and PHOMS. Among them, ODD and PHOMS are the local anatomical changes of the optic disc, and their relationship with the occurrence of NAION has received more and more attention in recent years. NAION is more likely to occur in eyes with ODD and PHOMS, and NAION patients with ODD and PHOMS have a high prevalence. In recent years, optical coherence tomography (OCT) and optical coherence tomography angiography(OCTA) can provide accurate an...
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Wenhao Shi Jiaxin Meng Xia Liu Ying Zhao Source Type: research

Reducing Re-fractures Post Percutaneous Kyphoplasty: The Impact of Zoledronic Acid with Calcium and Vitamin D3 in Osteoporotic Patients
CONCLUSIONS: Zoledronic acid in combination with calcium carbonate and vitamin D3 effectively enhances bone health in osteoporosis patients, warranting its clinical recommendation. This regimen shows promise for improving patient outcomes in osteoporosis management.PMID:38518159 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Weiqian Wu Wenbiao Zheng Weiwei Pan Fanghu Chen Langqing Jiang Source Type: research

The Impact of Prone Ventilation on Hypoxemia Following Extracorporeal Cardiac Surgery: A Meta Analysis
CONCLUSIONS: In the absence of significant hemodynamic changes, prone position ventilation significantly enhances the oxygenation index and reduces the duration of mechanical ventilation in patients undergoing extracorporeal circulation surgery. However, the observed heterogeneity across studies may be attributed to variations in breathing styles, respiratory techniques, and physiological parameters among different patient groups.PMID:38518160 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Jing Li Qingfang Yu Zhao Jian Tianpo Li Xiaojiao Jiang En Li Source Type: research

Impact of Combined Nifedipine and Aspirin Therapy on Hemodynamics in Patients with Early Eclampsia
CONCLUSIONS: The nifedipine and aspirin combination effectively treats pregnancy hypertension, enhancing both coagulation and hemorheology for improved maternal and fetal health outcomes.PMID:38518161 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Jinyu Fan Yujiao Yang Xiumei Wang Source Type: research

The Analysis of Transition Readiness of Adolescent Epilepsy Patients from Childhood to Adult from the Perspective of Disease Self-management: A Cross-sectional Study in Southwest China
CONCLUSION: Adolescent epilepsy patients exhibited moderate readiness for the transition from childhood to adulthood. Older patients with longer disease duration and stronger self-management skills displayed a higher level of readiness. Targeted clinical interventions that prioritize self-management skills are essential for facilitating a smoother transition into adulthood for patients.PMID:38518162 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Qing Xia Shuangzi Li Ting Wang Zhongxiu Qian Zhongping Li Qiaohong Zeng Liping Dong Huaying Yin Source Type: research

Efficacy and Safety of Topical Traditional Chinese Medicine Monotherapy in Persistent HPV Infection Among Males
CONCLUSION: Paiteling is convenient, safe, and effective for the treatment of persistent HPV infection in males.PMID:38518163 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Haiqian Yang Chengfang Zhang Yingyao Yu Kexin Li Min Liu Yonglong Gao Yuanyuan Shang Source Type: research

Association of Thyroid Autoantibodies with Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients
CONCLUSION: The level and positive rate of thyroid autoantibodies in patients with T2DM-DN were high and TPOAb positivity might be a risk factor for the occurrence of T2DM-DN.PMID:38518164 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Xia Chen Mengyan Chen Mengxia Chen Mingxia Ji Source Type: research

Re-Evaluation of Ipsilateral Multiple-Focal Breast Cancer: Case Report and Literature Review
CONCLUSION: This case highlights the need for more evidence-based data to support risk-level stratification of heterogenous foci and treatment decisions for ipsilateral multiple breast cancer and challenges current clinical practice.PMID:38518165 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Lei Hou Ziyi Fan Luming Zheng Source Type: research

Expression of Caudal-Type Homologous Transcription Factor-2 (CDX2) in Duodenal Carcinoma and its Relationship with Prognosis
CONCLUSION: CDX2 serves as an autonomous prognostic determinant in individuals diagnosed with duodenal cancer. Notably, patients exhibiting positive CDX2 expression demonstrate a considerably improved prognosis compared to those with negative CDX2 expression. CDX2 may play an important role as an tumor suppressor gene in the development of duodenal cancer. CDX2 can be used as an important factor for evaluating the prognosis of patients with duodenal cancer, and it has the potential to be a target for duodenal cancer therapy.PMID:38518166 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Jun Pan Xiaodong Jiao Zhihui Yang Jie Li Yitian Chen Xiaoyuan Chu Source Type: research

Therapeutic Benefits and Prognostic Value of a Model Based on 7 Immune-associated Genes in Bladder Cancer
CONCLUSION: The risk score model might be utilized to forecast the prognosis and efficacy of immunotherapy in BLCA patients, offering a novel course of treatment for these individuals. For patients undergoing immunotherapy, this gene signature can help predict treatment response. Low-risk patients may benefit from more tailored monitoring and personalized immunotherapy regimens. However, more investigations are required to validate its accuracy and effectiveness in a prospective cohort with larger sample sizes.PMID:38518167 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Ming Cao Yang Cao Song Xue Qi Zhang Haiyan Zhang Wei Xue Source Type: research

A Potential Therapeutic Approach According to Traditional Thai Medicine Theory for Post-COVID-19 Syndrome Treatment: An Observational Retrospective Clinical Study
CONCLUSIONS: The TTM clinical practice guideline for treating post-COVID-19 syndrome effectively improved the overall physical health capacity and symptoms associated with post-COVID-19 syndrome. Therefore, the implementation of this guideline, together with other approaches, could strengthen the treatment for post-COVID-19 to be more effective.PMID:38518168 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Julalak Chokpaisarn Pattaranun Bunhow Bodin Chatawatee Oratai Neamsuvan Pongthep Sutheravut Sompong Dowpiset Source Type: research

Effect of Phytochemical Compounds on Trichomonas tenax, an Oral Protozoan
Altern Ther Health Med. 2024 Mar 22:AT7352. Online ahead of print.ABSTRACTTrichomonas tenax is an oral protozoan with an estimated global pooled prevalence of 17% in the human population.1 Observational studies have demonstrated a significant statistical correlation between oral colonization by T. tenax and the progression of periodontal disease.2 Proposed pathogenic mechanisms for this protozoan include the production of tissue-damaging enzymes, induction of apoptosis in human cells, and dysbiosis of the oral microbiome.3 In patients for whom metronidazole (MTZ) is contraindicated, phytochemicals may offer a viable altern...
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Melissa K Stuart Hannah C Motes Deborah A Hudman Source Type: research

Effectiveness of Acupressure on Post-Cesarean Bowel Function: A Randomized Controlled Trial
CONCLUSIONS: Acupressure was found to be effective in improving bowel function after cesarean delivery, significantly reducing the time taken for participants to experience bowel sounds, flatulence, and bowel movements.PMID:38518170 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - March 22, 2024 Category: Complementary Medicine Authors: Yasemin S ökmen Resmiye Kaya Odaba ş Ayten Ta şpınar Source Type: research