Osimertinib tolerance in a patient with Stevens Johnson syndrome during osimertinib therapy after treatment with pembrolizumab
Osimertinib has emerged as an important tool in the treatment of non-small cell lung cancers (NSCLC) with certain activating mutations of epidermal growth factor receptor (EGFR). However, Osimertinib may cause... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 28, 2023 Category: Allergy & Immunology Authors: Michael Lopez, Garo Hagopian, Linda Doan, Benjamin J. Lee, Nathan W. Rojek, Janellen Smith, Sai-Hong Ignatius Ou, Yesim Yilmaz Demirdag and Misako Nagasaka Tags: Case report Source Type: research

Fatal eosinophilic myocarditis and submassive hepatic necrosis in lamotrigine induced DRESS syndrome
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare but severe and sometimes fatal adverse drug reaction that is known to occur with a number of antiepileptic drugs. It often follo... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 25, 2023 Category: Allergy & Immunology Authors: Khanh Duy Doan, Adeyinka Akinsanya, Matthew Kuhar and Hector Mesa Tags: Case report Source Type: research

Immunological responses in SARS-CoV-2 and HIV co-infection versus SARS-CoV-2 mono-infection: case report of the interplay between SARS-CoV-2 and HIV
There is an urgent need to understand the interplay between SARS-CoV-2 and HIV to inform risk-mitigation approaches for HIV-infected individuals. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 17, 2023 Category: Allergy & Immunology Authors: Shima Shahbaz, Wendy Sligl, Mohammed Osman and Shokrollah Elahi Tags: Case report Source Type: research

Cost-effectiveness analysis of biologics for the treatment of chronic rhinosinusitis with nasal polyps in Canada
Dupilumab, omalizumab, and mepolizumab are the three biologics currently approved for use in CRSwNP in Canada. Despite evidence of efficacy, their cost-effectiveness, which is a key factor influencing prescrib... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Michael Yong, Keshinisuthan Kirubalingam, Martin Y. Desrosiers, Shaun J. Kilty and Andrew Thamboo Tags: Research Source Type: research

Patient education in atopic dermatitis: a scoping review
Atopic dermatitis (AD) is a chronic inflammatory skin disease that affects children and adults. Poor treatment adherence in AD requires interventions to promote self-management; patient education in chronic di... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 13, 2023 Category: Allergy & Immunology Authors: Bethany Wilken, M. Zaman and Y. Asai Tags: Review Source Type: research

Barriers to penicillin allergy de-labeling in the inpatient and outpatient settings: a qualitative study
Penicillin allergy is the most commonly reported drug allergy in the US. Despite evidence demonstrating that up to 90% of labels are incorrect, scalable interventions are not well established. As part of a lar... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 11, 2023 Category: Allergy & Immunology Authors: Esra Alagoz, Megan Saucke, Prakash Balasubramanian, Paul Lata, Tyler Liebenstein and Sujani Kakumanu Tags: Research Source Type: research

Using the canadian egg ladder in children with food protein-induced enterocolitis syndrome: a case series
Current management of food protein-induced enterocolitis syndrome (FPIES) involves strict avoidance of the offending food for 12 –18 months, followed by oral food challenge (OFC) under physician supervision. OF... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - October 6, 2023 Category: Allergy & Immunology Authors: Linlei Ye, Tiffany Wong, Elana Lavine, Victoria E. Cook and Stephanie C. Erdle Tags: Research Source Type: research

Two cases of successful sirolimus treatment for patients with activated phosphoinositide 3-kinase δ syndrome 1
Activated phosphoinositide3-kinase (PI3K) δ syndrome 1 (APDS1) is a novel inborn errors of immunity (IEIs) caused by heterozygous gain of function mutations in PI3Kδ catalytic p110δ (PIK3CD). APDS1 has a spect... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 23, 2023 Category: Allergy & Immunology Authors: Lu Jiang, Xiaohan Hu, Qiang Lin, Ruyue Chen, Yunyan Shen, Yun Zhu, Qinying Xu and Xiaozhong Li Tags: Case report Source Type: research

Immunoglobulin utilization in Canada: a comparative analysis of provincial guidelines and a scoping review of the literature
Canada has high immunoglobulin (IG) product utilization, raising concerns about appropriate utilization, cost and risk of shortages. Currently, there is no national set of standardized IG guidelines, and consi... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 16, 2023 Category: Allergy & Immunology Authors: Megan Harmon, Kiarash Riazi, Jeannie Callum, Donald M. Arnold, Rebecca Barty, Davinder Sidhu, Nancy M. Heddle, Laurie MacLeod and Na Li Tags: Review Source Type: research

Mental health problems associated with idiopathic anaphylaxis
Idiopathic Anaphylaxis (IA) is the most common anaphylactic syndrome in adults. Mental health problems associated with IA are not well recognised. We aimed to assess if patients diagnosed with IA were more lik... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Logan S Gardner, Zihao Tan, David Brown, David Gillis, James G. Scott and Roger Prentice Tags: Research Source Type: research

Treatment of idiopathic anaphylaxis with dupilumab: a case report
Anaphylaxis is an acute, potentially life-threatening allergic reaction that typically occurs after exposure to a trigger, while idiopathic anaphylaxis (IA) occurs in the absence of a trigger. Acute management... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 9, 2023 Category: Allergy & Immunology Authors: Elizabeth Pepper and Luke Pittman Tags: Case report Source Type: research

Validity of fractional exhaled nitric oxide and small airway lung function measured by IOS in the diagnosis of cough variant asthma in preschool children with chronic cough
To investigate the role of combined impulse oscillometry (IOS) and fractional exhaled nitric oxide (FeNO) in the diagnosis of cough variant asthma (CVA) in preschool children. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 9, 2023 Category: Allergy & Immunology Authors: Ying Hu, Shouyan Zheng, Zhiqiang Chen, Dan Yu, Tianxia Lai, Yao Chen and Wei Liao Tags: Research Source Type: research

PRevalence of the Eosinophilic Phenotype Among SeveRE asthma patients in Lebanon: results of the PREPARE study
This study aimed at determining the prevalence of the eosinophilic phenotype defined as an... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 8, 2023 Category: Allergy & Immunology Authors: Wajdi Abi Saleh, Zuhair Alameh, Zeina Aoun Bacha, Joudy Bahous, Pierre Bou Khalil, Zahia Chahine, Hassan Chami, Georges Dabar, Hassan Dheiny, Alfred Dib, Dany farhat, Carla Irani, Georges Juvelekian, Nadim Kanj, Bassam Mansour, Moussa Riachi & hellip; Tags: Research Source Type: research

A case of possible anaphylaxis to ASA and structurally unrelated NSAIDs
Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of medications, and are among the leading causes of drug hypersensitivity. NSAIDs hypersensitivity reactions are classif... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - September 8, 2023 Category: Allergy & Immunology Authors: Sarah Edgerley and Harold Kim Tags: Case report Source Type: research

Correlations between IL-36 family cytokines in peripheral blood and subjective and objective assessment results in patients with allergic rhinitis
Interleukin (IL)-36 family cytokines have received increasing attention, especially in the fields of inflammation and immunity research. However, whether IL-36 family cytokine levels are correlated with the re... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - August 30, 2023 Category: Allergy & Immunology Authors: Jia Gu, Gang Qin, Liang Jiang, Wei Xu, Yuanyuan Wang, Jiangxue Liao, Hongzhu Pan and Zhuoping Liang Tags: Research Source Type: research