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Two-stage association study of mitochondrial DNA variants in allergic rhinitis
This study aimed to better understand the mitochondrial genome profile with AR and to investigate the as... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 23, 2024 Category: Allergy & Immunology Authors: Huajie Yuan, Lingling Wang, Song Wang, Linge Li, Qingping Liu, Yan Wang, Yuping Yang and Hua Zhang Tags: Research Source Type: research

Association between interleukin-6-174G/C gene polymorphism and asthma severity: exploring the role of total serum IgE, blood eosinophils, and FeNO as markers of type 2 inflammation
While a connection has been established between serum interleukin-6 (IL-6) levels and the IL-6 gene ( − 174G/C) polymorphism in allergic diseases such as asthma, its specific association with severe asthma remains... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 22, 2024 Category: Allergy & Immunology Authors: Mona Al-Ahmad, Asmaa Ali, Ahmed Maher and Mohammad Z. Haider Tags: Research Source Type: research

Immune endotyping and gene expression profile of patients with chronic rhinosinusitis with nasal polyps in the aspirin-exacerbated respiratory disease (AERD) and the non-AERD subgroups
Chronic Rhinosinusitis (CRS) is a paranasal sinus inflammatory disease and is divided into two subgroups defined as CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). CRSwNP displays a T hel... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 15, 2024 Category: Allergy & Immunology Authors: Javad Nazari, Faezeh Shahba, Negin Jafariaghdam, Saleh Mohebbi, Saba Arshi, Mohammad Hassan Bemanian, Morteza Fallahpour, Sima Shokri, Fatemeh Atashrazm, Saeed Amini, Maryam Roomiani, Mahnaz Jamee, Pegah Babaheidarian, Majid Khoshmirsafa and Mohammad Naba Tags: Research Source Type: research

Acuity of asthma exacerbations in Alberta, Canada is increasing: a population-based study
Asthma is a common respiratory illness affecting 2.8 million Canadians, including 9.7% of Albertans. Prior studies showed a substantial decrease in ED visits for asthma in the decade preceding 2010, followed b... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 12, 2024 Category: Allergy & Immunology Authors: Adil Adatia, Jalal Moolji and Imran Satia Tags: Research Source Type: research

Prevalence of asthma in people with type 1 diabetes mellitus: a scoping review
According to the Th1/Th2 paradigm, the expansion of Th1-type clones in individuals with type 1 diabetes results in reduced Th2-type clones, preventing the development of atopic diseases and vice versa. However... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 8, 2024 Category: Allergy & Immunology Authors: J úlia Marchatto Kamei, Raissa Dias Maués, Gabriel de Oliveira Silva, Alessandra Helena Machado, Erika Megumi Hoshino, Fabiana Menezes Bacchiega, Laís Mota Furtado Sena and Carlos Antonio Negrato Tags: Review Source Type: research

Real-world outcomes of mepolizumab for the treatment of severe eosinophilic asthma in Canada: an observational study
Mepolizumab, the first widely available anti-interleukin 5 biologic, targets eosinophilic inflammation and has been shown in clinical trials to reduce exacerbations, oral corticosteroid dependence, and healthc... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 4, 2024 Category: Allergy & Immunology Authors: Kenneth R. Chapman, Kathryn Cogger, Erin Arthurs, Callahan LaForty, Shane Golden, Bradley Millson, Koyo Usuba and Christopher Licskai Tags: Research Source Type: research

Delayed presentation of food protein-induced enterocolitis syndrome (FPIES) to okra in a toddler
Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE) -mediated food allergy predominantly observed in infants and characterized by the delayed onset of vomiting following ingesti... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 3, 2024 Category: Allergy & Immunology Authors: Hunter Hall, Sara Anvari, Fallon Schultz, Olubukola Ojuola and Nicholas L. Rider Tags: Case report Source Type: research

The prevalence of obstructive sleep apnea in Japanese asthma patients
Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the general population because these conditions share some comorbidities. In Japan, the prevalence of OSA in the general population... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 3, 2024 Category: Allergy & Immunology Authors: Mina Yasuda, Kazunori Tobino, Norihiro Harada, Ryunosuke Ooi, Takuto Sueyasu, Saori Nishizawa, Miyuki Munechika, Kohei Yoshimine, Yuki Ko, Yuki Yoshimatsu, Kosuke Tsuruno, Hiromi Ide and Kazuhisa Takahashi Tags: Research Source Type: research

Association of single nucleotide polymorphisms in the F2RL1 gene with clinical and inflammatory characteristics of patients with asthma
Proteinase-activated receptor 2 (PAR-2) is a G-protein coupled receptor associated with many inflammatory diseases, including asthma. We have shown an association between PAR-2 expression in peripheral blood m... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - February 2, 2024 Category: Allergy & Immunology Authors: Nami Shrestha Palikhe, Qahir Haji, Emily Mack, Tristan Sinnatamby, Andrew J. Sandford, Lisa Cameron and Harissios Vliagoftis Tags: Research Source Type: research

Resource utilization and cost assessment of a proactive penicillin allergy de-labeling program for low-risk inpatients
Resource utilization and costs can impede proactive assessment and de-labeling of penicillin allergy among inpatients. (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - January 22, 2024 Category: Allergy & Immunology Authors: Derek Lanoue, Adhora Mir, Carl van Walraven, Timothy Olynych, Caroline Nott and Derek R. MacFadden Tags: Research Source Type: research

Inborn errors of immunity in adulthood
Inborn errors of immunity (IEIs) are a group of conditions whereby parts of the immune system are missing or dysfunctional. Once thought to primarily be a pediatric disorder, it is now estimated that more than... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - January 17, 2024 Category: Allergy & Immunology Authors: Joanne J. F. Wang, Ar ün Dhir, Kyla J. Hildebrand, Stuart E. Turvey, Robert Schellenberg, Luke Y. C. Chen, Persia Pourshahnazari and Catherine M. Biggs Tags: Review Source Type: research

Update on the association between Helicobacter pylori infection and asthma in terms of microbiota and immunity
H. pylori is a gram-negative bacterium that is usually acquired in childhood and can persistently colonize the gastric mucosa of humans, affecting approximately half of the world ’s population. In recent years,... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - January 14, 2024 Category: Allergy & Immunology Authors: Mengmeng Liu, Yong Wang and Bing Du Tags: Review Source Type: research

Accelerometer-derived sleep metrics in mild and difficult-to-treat asthma
Poor sleep health is associated with increased asthma morbidity and mortality. Accelerometers have been validated to assess sleep parameters though studies using this method in patients with asthma are sparse ... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - January 14, 2024 Category: Allergy & Immunology Authors: Varun Sharma, Helen Clare Ricketts, Femke Steffensen, Anna Goodfellow, Duncan S Buchan and Douglas C Cowan Tags: Letter to the editor Source Type: research

Different expression levels of interleukin-36 in asthma phenotypes
Interleukin (IL)-36 family is closely associated with inflammation and consists of IL-36 α, IL-36β, IL-36γ, and IL-36Ra. The role of IL-36 in the context of asthma and asthmatic phenotypes is not well character... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - January 13, 2024 Category: Allergy & Immunology Authors: Jinyan Li, Zhengda Wang, Hongna Dong, Yuqiu Hao, Peng Gao and Wei Li Tags: Research Source Type: research

Pollen food allergy syndrome secondary to molds and raw mushroom cross-reactivity: a case report
Pollen food allergy syndrome (PFAS) is an immunoglobulin E (IgE) mediated reaction that causes oropharyngeal pruritus or angioedema due to homologous proteins present in the culprit food as well as a sensitizi... (Source: Allergy, Asthma and Clinical Immunology)
Source: Allergy, Asthma and Clinical Immunology - January 4, 2024 Category: Allergy & Immunology Authors: Ryan Gauld, Graham Walter and Rongbo Zhu Tags: Case report Source Type: research