Alcoholism: Clinical and Experimental Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Rate-dependent effects of narrative interventions in a longitudinal study of individuals who use alcohol
CONCLUSION: The evidence of a rate-dependent effect of EFT on delay discounting rates offers a more nuanced, mechanistic understanding of this novel therapeutic intervention and can allow more precise treatment targeting by demonstrating who is likely to receive the most benefit from it.PMID:36810763 | DOI:10.1111/acer.15020 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: William H Craft Candice L Dwyer Devin C Tomlinson Yu-Hua Yeh Allison N Tegge Warren K Bickel Source Type: research

Effects of topiramate therapy on serum bicarbonate concentration in a sample of 10,279 veterans
CONCLUSIONS: The excess prevalence of metabolic acidosis associated with topiramate treatment does not differ with dosage, alcohol consumption, or the presence of an AUD. Baseline and periodic serum bicarbonate concentration measurements are recommended during topiramate therapy. Patients prescribed topiramate should be educated about the symptoms of metabolic acidosis and urged to report their occurrence promptly to a healthcare provider.PMID:36810985 | DOI:10.1111/acer.15011 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Michelle S Naps Shirley H Leong Emily E Hartwell Christopher T Rentsch Henry R Kranzler Source Type: research

An investigation of the utility of the Australian Guide to the diagnosis of fetal alcohol spectrum disorder in young children
CONCLUSIONS: These results highlight the complexity of presentation and the extent of impairment in the sample. The use of comorbid diagnoses to substantiate a "severe" designation in specific neurodevelopmental domains raises the question of whether there were false-positive diagnoses. The complexity of determining causal relationships between exposure to PAE and early life adversity on developmental outcomes continues to be a challenge in this young population.PMID:36810987 | DOI:10.1111/acer.15012 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Sharon Dawe Elizbeth Eggins Joseph Betts Heidi Webster Tania Pomario Jessica Doak Ned Chandler-Mather Denise Hatzis Haydn Till Paul Harnett Andrew Wood Doug Shelton Source Type: research

The role of effortful control in mitigating negative consequences associated with emerging adult drinking
CONCLUSIONS: The results provide some evidence that very high levels of attentional and activation control protect against alcohol-related negative consequences associated with drinking. Emerging adults who are very high in attentional and activation control are likely better able to control their attention and engage in goal-directed behavior, like leaving a party at a reasonable hour, or attending school and/or work when experiencing the punishing effects of a hangover. Results emphasize the importance of distinguishing facets of self-regulation when testing self-regulation models.PMID:36811151 | DOI:10.1111/acer.15016 (...
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Katie J Paige Rachael J Shaw Craig R Colder Source Type: research

Sleep disturbances in Norwegian children with fetal alcohol spectrum disorders (FASD) with and without a diagnosis of attention-deficit hyperactivity disorder or epilepsy
CONCLUSION: Problems with sleep are very common in FASD children and seem independent of FASD subgroup and the presence of epilepsy or a pathological EEG finding, while those with ADHD had more sleep problems. The study underscores the importance of screening for sleep disturbances in all children with FASD as these problems may be treatable.PMID:36811179 | DOI:10.1111/acer.15009 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Thorsten Gerstner Hans Inge Saevareid Åse Ribe Johnsen Gro L øhaugen Jon Skranes Source Type: research

Validation of the quantification of phosphatidylethanol 16:0/18:1 concentrations in TASSO-M20 devices
CONCLUSIONS: Our data support the utility, accuracy, and feasibility of using the TASSO-M20 device for blood self-collection during a virtual study. The TASSO-M20 device had multiple advantages over the typical finger stick method, including consistent blood collection, participant acceptability, and less discomfort as indicated by acceptability interviews.PMID:36811188 | DOI:10.1111/acer.15024 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Julianne D Jett Rachael Beck Diana Tyutyunnyk Jesus Sanchez Marisa Lopez-Cruzan Brett C Ginsburg Sterling M McPherson Martin A Javors Michael G McDonell Nathalie Hill-Kapturczak Source Type: research

Adverse childhood experiences in children with fetal alcohol spectrum disorders and their effects on behavior
This study describes ACEs in children with FASD and how they impact behavior problems.METHODS: A convenience sample of 87 caregivers of children (aged 3 to 12) with FASD participating in an intervention study reported on their children's ACEs using the ACEs Questionnaire and behavior problems on the Eyberg Child Behavior Inventory (ECBI). A theorized three-factor structure of the ECBI (Oppositional Behavior, Attention Problems, and Conduct Problems) was investigated. Data were analyzed using Pearson correlations and linear regression.RESULTS: On average, caregivers endorsed 3.10 (SD = 2.99) ACEs experienced by their childr...
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Carson Kautz-Turnbull Madeline Rockhold Elizabeth D Handley Heather Carmichael Olson Christie Petrenko Source Type: research

Cortisol as a risk biomarker to guide recovery from substance use disorders
Alcohol Clin Exp Res. 2023 Feb 21. doi: 10.1111/acer.15018. Online ahead of print.NO ABSTRACTPMID:36811294 | DOI:10.1111/acer.15018 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Taylor Fitzpatrick-Schmidt Scott Edwards Source Type: research

Cost-effectiveness and cost-utility analyses of a web-based computer-tailored intervention for prevention of binge drinking among Spanish adolescents
CONCLUSIONS: Computer-tailored feedback is a cost-effective way to reduce BD and increase QALYs among adolescents. However, long-term follow-up is needed to evaluate more fully changes in both BD and health-related quality of life.PMID:36811462 | DOI:10.1111/acer.14990 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 22, 2023 Category: Addiction Authors: Ana Magdalena Vargas-Mart ínez Marta Lima-Serrano Marta Trapero-Bertran Source Type: research

Corrigendum
Alcohol Clin Exp Res. 2023 Feb 19. doi: 10.1111/acer.14793. Online ahead of print.NO ABSTRACTPMID:36802072 | DOI:10.1111/acer.14793 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 21, 2023 Category: Addiction Source Type: research

Advancing screening for FASD: Commentary on "validation of the FASD-Tree as a screening tool for fetal alcohol spectrum disorders"
Alcohol Clin Exp Res. 2023 Feb 17. doi: 10.1111/acer.15033. Online ahead of print.NO ABSTRACTPMID:36799086 | DOI:10.1111/acer.15033 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 17, 2023 Category: Addiction Authors: Michelle Kuhn Source Type: research

Interleukin-22 alleviates alcohol-associated hepatic fibrosis, inhibits autophagy, and suppresses the PI3K/AKT/mTOR pathway in mice
CONCLUSIONS: IL-22 exerts a marked protective effect against alcohol-associated hepatic fibrosis. Its effect may be partly related to the alteration of autophagy-related gene expression and inhibition of the PI3K/AKT/mTOR pathway in the liver.PMID:36799106 | DOI:10.1111/acer.15021 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 17, 2023 Category: Addiction Authors: Yu-Xi Meng Rui Zhao Li-Juan Huo Source Type: research

Indomethacin restores loss of hippocampal neurogenesis and cholinergic innervation and reduces innate immune expression and reversal learning deficits in adult male and female rats following adolescent ethanol exposure
CONCLUSIONS: These data suggest that in males and females, (1) AIE persistent neuroimmune induction mediates both the loss of adult hippocampal DCX and loss of basal forebrain cholinergic neurons and their innervation to hippocampal targets, and (2) anti-inflammatory indomethacin treatment following AIE that restores these persistent molecular pathologies also restores spatial reversal learning deficits.PMID:36799290 | DOI:10.1111/acer.15019 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 17, 2023 Category: Addiction Authors: Victoria Macht Ryan Vetreno Natalie Elchert Rachael Fisher Fulton Crews Source Type: research

Impact of alcohol use disorder severity on human immunodeficiency virus (HIV) viral suppression and CD4 count in three international cohorts of people with HIV
CONCLUSIONS: In three cohorts of PWH, AUD severity was not associated with HIV viral suppression or CD4 count. PWH with AUD in the current era of antiretroviral therapy can achieve virologic control.PMID:36799302 | DOI:10.1111/acer.15031 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 17, 2023 Category: Addiction Authors: Nicolas Bertholet Richard Saitz Judith A Hahn Timothy C Heeren Nneka I Emenyonu Matthew Freiberg Michael R Winter Theresa W Kim Kara M Magane Christine Lloyd-Travaglini Robin Fatch Kendall Bryant Leah S Forman Lindsey Rateau Elena Blokhina Winnie R Muyind Source Type: research

Latent classes of neurodevelopmental profiles and needs in children and adolescents with prenatal alcohol exposure
CONCLUSIONS: Four relatively distinct subgroups were present in a large heterogeneous sample of children and adolescents with PAE assessed for FASD in Canada. These findings may inform clinical services by guiding clinicians to identify distinct service pathways for these subgroups, potentially increasing access to a more personalized treatment approach and improving outcomes.PMID:36799306 | DOI:10.1111/acer.15028 (Source: Alcoholism, Clinical and Experimental Research)
Source: Alcoholism, Clinical and Experimental Research - February 17, 2023 Category: Addiction Authors: Kaitlyn McLachlan Meenu Minhas Chantel Ritter Kathleen Kennedy Vannesa Joly Martina Faitakis Jocelynn Cook Kathy Unsworth James MacKillop Jacqueline Pei Source Type: research