Effect of dolutegravir-based versus efavirenz-based antiretroviral therapy on excessive weight gain in adult treatment-na ïve HIV patients at Matsanjeni health center, Eswatini: a retrospective cohort study
There is limited data on dolutegravir (DTG)-associated weight gain from settings with a dual burden of HIV and overnutrition. (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - January 7, 2024 Category: Infectious Diseases Authors: Didier M. Mukuna, Tom Decroo and Clara M. Nyapokoto Tags: Research Source Type: research

Brief communications: changes in inflammatory biomarkers and lipid profiles after switching to long-acting cabotegravir plus rilpivirine
AIDS Res Ther. 2024 Jan 3;21(1):1. doi: 10.1186/s12981-023-00590-4.ABSTRACTWe assessed whether the impact of cabotegravir plus rilpivirine on inflammation reduction differs from that of oral antiretrovirals, using real-world data. Inflammatory biomarkers and lipid profiles were followed from baseline to 8 months after switching. Seventy-eight participants were analyzed. The CD4/CD8 ratio and C-reactive protein did not change. There were transient decreases in CD8 and CD4 counts in the group that switched from the dolutegravir-based regimen, but not in the tenofovir alafenamide-based regimen group. High-density lipoprotein ...
Source: AIDS Research and Therapy - January 4, 2024 Category: Infectious Diseases Authors: Eisuke Adachi Makoto Saito Amato Otani Michiko Koga Hiroshi Yotsuyanagi Source Type: research

Empyema caused by Streptococcus constellatus in a patient infected with HIV: a case report and literature review
CONCLUSIONS: S. constellatus should not be neglected as a pus pathogen in patients with HIV. comprehensive treatment is important for empyema of S. constellatus.PMID:38173032 | PMC:PMC10765925 | DOI:10.1186/s12981-023-00587-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - January 4, 2024 Category: Infectious Diseases Authors: Hong-Hong Yang Mei Li Qing Yu Qian Liu Min Liu Source Type: research

Brief communications: changes in inflammatory biomarkers and lipid profiles after switching to long-acting cabotegravir plus rilpivirine
AIDS Res Ther. 2024 Jan 3;21(1):1. doi: 10.1186/s12981-023-00590-4.ABSTRACTWe assessed whether the impact of cabotegravir plus rilpivirine on inflammation reduction differs from that of oral antiretrovirals, using real-world data. Inflammatory biomarkers and lipid profiles were followed from baseline to 8 months after switching. Seventy-eight participants were analyzed. The CD4/CD8 ratio and C-reactive protein did not change. There were transient decreases in CD8 and CD4 counts in the group that switched from the dolutegravir-based regimen, but not in the tenofovir alafenamide-based regimen group. High-density lipoprotein ...
Source: AIDS Research and Therapy - January 4, 2024 Category: Infectious Diseases Authors: Eisuke Adachi Makoto Saito Amato Otani Michiko Koga Hiroshi Yotsuyanagi Source Type: research

Empyema caused by Streptococcus constellatus in a patient infected with HIV: a case report and literature review
CONCLUSIONS: S. constellatus should not be neglected as a pus pathogen in patients with HIV. comprehensive treatment is important for empyema of S. constellatus.PMID:38173032 | PMC:PMC10765925 | DOI:10.1186/s12981-023-00587-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - January 4, 2024 Category: Infectious Diseases Authors: Hong-Hong Yang Mei Li Qing Yu Qian Liu Min Liu Source Type: research

Brief communications: changes in inflammatory biomarkers and lipid profiles after switching to long-acting cabotegravir plus rilpivirine
AIDS Res Ther. 2024 Jan 3;21(1):1. doi: 10.1186/s12981-023-00590-4.ABSTRACTWe assessed whether the impact of cabotegravir plus rilpivirine on inflammation reduction differs from that of oral antiretrovirals, using real-world data. Inflammatory biomarkers and lipid profiles were followed from baseline to 8 months after switching. Seventy-eight participants were analyzed. The CD4/CD8 ratio and C-reactive protein did not change. There were transient decreases in CD8 and CD4 counts in the group that switched from the dolutegravir-based regimen, but not in the tenofovir alafenamide-based regimen group. High-density lipoprotein ...
Source: AIDS Research and Therapy - January 4, 2024 Category: Infectious Diseases Authors: Eisuke Adachi Makoto Saito Amato Otani Michiko Koga Hiroshi Yotsuyanagi Source Type: research

Empyema caused by Streptococcus constellatus in a patient infected with HIV: a case report and literature review
CONCLUSIONS: S. constellatus should not be neglected as a pus pathogen in patients with HIV. comprehensive treatment is important for empyema of S. constellatus.PMID:38173032 | DOI:10.1186/s12981-023-00587-z (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - January 4, 2024 Category: Infectious Diseases Authors: Hong-Hong Yang Mei Li Qing Yu Qian Liu Min Liu Source Type: research

Empyema caused by Streptococcus constellatus in a patient infected with HIV: a case report and literature review
Empyema caused by Streptococcus constellatus (S. constellatus) is rare in patients with HIV. To analyze the clinical data of a patient living with HIV (PLHIV), who got empyema caused by S. constellatus, invest... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - January 3, 2024 Category: Infectious Diseases Authors: Hong-Hong Yang, Mei Li, Qing Yu, Qian Liu and Min Liu Tags: Case Report Source Type: research

Brief communications: changes in inflammatory biomarkers and lipid profiles after switching to long-acting cabotegravir plus rilpivirine
We assessed whether the impact of cabotegravir plus rilpivirine on inflammation reduction differs from that of oral antiretrovirals, using real-world data. Inflammatory biomarkers and lipid profiles were follo... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - January 3, 2024 Category: Infectious Diseases Authors: Eisuke Adachi, Makoto Saito, Amato Otani, Michiko Koga and Hiroshi Yotsuyanagi Tags: Research Source Type: research

Adolescent's and youth's adherence to antiretroviral therapy for better treatment outcome and its determinants: multi-center study in public health facilities
CONCLUSION: The adherence rate in this study was low which is below the recommended adherence level. Being female, taking additional medication beside ART and presence of opportunistic infection were determinants of adherence. As a result, significant work must be done on opportunistic infection prevention through health education and promotion for screening and risk reduction. Similarly, adolescents and youths service integration with the ART Clinic is strongly advised.PMID:38115098 | PMC:PMC10729566 | DOI:10.1186/s12981-023-00588-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - December 20, 2023 Category: Infectious Diseases Authors: Yihenew Zurbachew Desta Hiko Girma Bacha Hailu Merga Source Type: research

Adolescent's and youth's adherence to antiretroviral therapy for better treatment outcome and its determinants: multi-center study in public health facilities
CONCLUSION: The adherence rate in this study was low which is below the recommended adherence level. Being female, taking additional medication beside ART and presence of opportunistic infection were determinants of adherence. As a result, significant work must be done on opportunistic infection prevention through health education and promotion for screening and risk reduction. Similarly, adolescents and youths service integration with the ART Clinic is strongly advised.PMID:38115098 | PMC:PMC10729566 | DOI:10.1186/s12981-023-00588-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - December 20, 2023 Category: Infectious Diseases Authors: Yihenew Zurbachew Desta Hiko Girma Bacha Hailu Merga Source Type: research

Adolescent's and youth's adherence to antiretroviral therapy for better treatment outcome and its determinants: multi-center study in public health facilities
CONCLUSION: The adherence rate in this study was low which is below the recommended adherence level. Being female, taking additional medication beside ART and presence of opportunistic infection were determinants of adherence. As a result, significant work must be done on opportunistic infection prevention through health education and promotion for screening and risk reduction. Similarly, adolescents and youths service integration with the ART Clinic is strongly advised.PMID:38115098 | PMC:PMC10729566 | DOI:10.1186/s12981-023-00588-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - December 20, 2023 Category: Infectious Diseases Authors: Yihenew Zurbachew Desta Hiko Girma Bacha Hailu Merga Source Type: research

Adolescent's and youth's adherence to antiretroviral therapy for better treatment outcome and its determinants: multi-center study in public health facilities
CONCLUSION: The adherence rate in this study was low which is below the recommended adherence level. Being female, taking additional medication beside ART and presence of opportunistic infection were determinants of adherence. As a result, significant work must be done on opportunistic infection prevention through health education and promotion for screening and risk reduction. Similarly, adolescents and youths service integration with the ART Clinic is strongly advised.PMID:38115098 | PMC:PMC10729566 | DOI:10.1186/s12981-023-00588-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - December 20, 2023 Category: Infectious Diseases Authors: Yihenew Zurbachew Desta Hiko Girma Bacha Hailu Merga Source Type: research

Adolescent's and youth's adherence to antiretroviral therapy for better treatment outcome and its determinants: multi-center study in public health facilities
CONCLUSION: The adherence rate in this study was low which is below the recommended adherence level. Being female, taking additional medication beside ART and presence of opportunistic infection were determinants of adherence. As a result, significant work must be done on opportunistic infection prevention through health education and promotion for screening and risk reduction. Similarly, adolescents and youths service integration with the ART Clinic is strongly advised.PMID:38115098 | PMC:PMC10729566 | DOI:10.1186/s12981-023-00588-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - December 20, 2023 Category: Infectious Diseases Authors: Yihenew Zurbachew Desta Hiko Girma Bacha Hailu Merga Source Type: research

Adolescent's and youth's adherence to antiretroviral therapy for better treatment outcome and its determinants: multi-center study in public health facilities
CONCLUSION: The adherence rate in this study was low which is below the recommended adherence level. Being female, taking additional medication beside ART and presence of opportunistic infection were determinants of adherence. As a result, significant work must be done on opportunistic infection prevention through health education and promotion for screening and risk reduction. Similarly, adolescents and youths service integration with the ART Clinic is strongly advised.PMID:38115098 | PMC:PMC10729566 | DOI:10.1186/s12981-023-00588-y (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - December 20, 2023 Category: Infectious Diseases Authors: Yihenew Zurbachew Desta Hiko Girma Bacha Hailu Merga Source Type: research