Estimating prevalence and modelling correlates of HIV test positivity among female sex workers, men who have sex with men, people who inject drugs, transgender people and prison inmates in Sierra Leone, 2021
Key populations (KPs) are particularly vulnerable to HIV infection and efforts to prevent HIV infections among KPs have been less successful, largely due to existing laws and legislation that classify the grou... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 27, 2023 Category: Infectious Diseases Authors: Duah Dwomoh, Issata Wurie, Yvonne Harding, Kojo Mensah Sedzro, Joseph Kandeh, Henry Tagoe, Christabel Addo, Daniel Kojo Arhinful, Abdul Rahman Cherinoh Sessay, James Lahai Kamara, Kemoh Mansaray and William Kwabena Ampofo Tags: Research Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
AIDS Res Ther. 2023 Sep 20;20(1):69. doi: 10.1186/s12981-023-00556-6.ABSTRACTTransgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural factors affecting PrEP delivery amongst TWSS are underexplored in the literature. We conducted ethnographic research to examine how multilevel social and structural factors manifest in TWSS's lived experiences and affect PrEP delivery and use. Twenty-four transgender women were recruited from the SAPPHIRE cohort and completed interviews focuse...
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E Cooney Katherine H A Footer Jennifer L Glick Anna Passaniti Meridian Howes Susan G Sherman Source Type: research

Understanding the social and structural context of oral PrEP delivery: an ethnography exploring barriers and facilitators impacting transgender women who engage in street-based sex work in Baltimore, Maryland
Transgender women who sell sex (TWSS) experience high rates of HIV acquisition. Antiretrovirals for pre-exposure prophylaxis (PrEP) represent an efficacious HIV prevention strategy. The social and structural f... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 20, 2023 Category: Infectious Diseases Authors: Erin E. Cooney, Katherine H. A. Footer, Jennifer L. Glick, Anna Passaniti, Meridian Howes and Susan G. Sherman Tags: Research Source Type: research

HIV viral load suppression among people with mental disorders at two urban HIV clinics in Uganda: a parallel convergent mixed methods study using the social ecological model
CONCLUSION AND RECOMMENDATIONS: HIV VLS among PLHIV with mental disorders at institutions that provide integrated HIV and mental health care is still below the UNAIDS 95% target. Health promotion messaging focusing on benefits of VLS and countering stigma to create a safe environment; and active involvement of family members in care could improve HIV treatment outcomes for PLHIV with mental disorders.PMID:37726822 | PMC:PMC10510257 | DOI:10.1186/s12981-023-00567-3 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 19, 2023 Category: Infectious Diseases Authors: Regina Ndagire Rachel Nante Wangi Kevin Ouma Ojiambo Joanita Nangendo Juliet Nakku Herbert Muyinda Fred C Semitala Source Type: research

HIV viral load suppression among people with mental disorders at two urban HIV clinics in Uganda: a parallel convergent mixed methods study using the social ecological model
CONCLUSION AND RECOMMENDATIONS: HIV VLS among PLHIV with mental disorders at institutions that provide integrated HIV and mental health care is still below the UNAIDS 95% target. Health promotion messaging focusing on benefits of VLS and countering stigma to create a safe environment; and active involvement of family members in care could improve HIV treatment outcomes for PLHIV with mental disorders.PMID:37726822 | DOI:10.1186/s12981-023-00567-3 (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 19, 2023 Category: Infectious Diseases Authors: Regina Ndagire Rachel Nante Wangi Kevin Ouma Ojiambo Joanita Nangendo Juliet Nakku Herbert Muyinda Fred C Semitala Source Type: research

HIV viral load suppression among people with mental disorders at two urban HIV clinics in Uganda: a parallel convergent mixed methods study using the social ecological model
Uganda adopted and implemented the Universal Test and Treat (UTT) guidelines in 2017, which require HIV-infected persons to be initiated on antiretroviral therapy (ART) at any CD4  + cell count, and to be routi... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 19, 2023 Category: Infectious Diseases Authors: Regina Ndagire, Rachel Nante Wangi, Kevin Ouma Ojiambo, Joanita Nangendo, Juliet Nakku, Herbert Muyinda and Fred C. Semitala Tags: Research Source Type: research

Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa
Suboptimal antiretroviral (ART) adherence can lead to virologic failure with consequent HIV-1 resistance. Tenofovir diphosphate (TFV-DP) in dried blood spots (DBS) is a powerful biomarker of cumulative adheren... (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 14, 2023 Category: Infectious Diseases Authors: Y. Singh, J. Castillo-Mancilla, R. Madimabe, L. Jennings, C. M. Ferraris, R. N. Robbins, P. L. Anderson, R. H. Remien and C. Orrell Tags: Research Source Type: research

Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa
CONCLUSION: TFV-DP in DBS showed a step-wise inverse relationship with VB and drug resistance, with evidence of low cumulative ART adherence in PWH who developed antiretroviral resistance. Monitoring TFV-DP concentrations could be a valuable tool for predicting future VB and future resistance.PMID:37705102 | PMC:PMC10500931 | DOI:10.1186/s12981-023-00552-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 13, 2023 Category: Infectious Diseases Authors: Y Singh J Castillo-Mancilla R Madimabe L Jennings C M Ferraris R N Robbins P L Anderson R H Remien C Orrell Source Type: research

Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa
CONCLUSION: TFV-DP in DBS showed a step-wise inverse relationship with VB and drug resistance, with evidence of low cumulative ART adherence in PWH who developed antiretroviral resistance. Monitoring TFV-DP concentrations could be a valuable tool for predicting future VB and future resistance.PMID:37705102 | PMC:PMC10500931 | DOI:10.1186/s12981-023-00552-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 13, 2023 Category: Infectious Diseases Authors: Y Singh J Castillo-Mancilla R Madimabe L Jennings C M Ferraris R N Robbins P L Anderson R H Remien C Orrell Source Type: research

Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa
CONCLUSION: TFV-DP in DBS showed a step-wise inverse relationship with VB and drug resistance, with evidence of low cumulative ART adherence in PWH who developed antiretroviral resistance. Monitoring TFV-DP concentrations could be a valuable tool for predicting future VB and future resistance.PMID:37705102 | PMC:PMC10500931 | DOI:10.1186/s12981-023-00552-w (Source: AIDS Research and Therapy)
Source: AIDS Research and Therapy - September 13, 2023 Category: Infectious Diseases Authors: Y Singh J Castillo-Mancilla R Madimabe L Jennings C M Ferraris R N Robbins P L Anderson R H Remien C Orrell Source Type: research