Advances in Small Animal Medicine and Surgery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Oral administration of famciclovir for treatment of feline herpesvirus type 1 infections
Famciclovir, an oral prodrug of penciclovir, is an increasingly common treatment for FHV-1 –infected cats. Penciclovir is a nucleoside deoxyguanosine analog with potent antiviral activity against HSV-1, HSV-2, and varicella zoster virus, as well as variable in vitro activity against FHV-1. Penciclovir is consistently more potent than acyclovir, the only other drug used for the systemic treatment of cats infected with FHV-1. Penciclovir has low bioavailability in humans, and an oral prodrug, famciclovir, is used instead. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - January 1, 2018 Category: Veterinary Research Tags: Respiratory Medicine Source Type: research

Use of poliglecaprone for perineal urethrostomy in Cats
Perineal urethrostomy (PU) is predominantly performed in male cats to bypass the distal portion of the urethra and create a permanent opening between the pelvic urethra and perineal skin. Primary indications for PU include recurrent distal urethral obstruction secondary to feline lower urinary tract disease or urolithiasis (especially when medical attempts to prevent recurrent obstruction have failed), trauma to the distal portion of the urethra, and idiopathic distal urethral obstruction. Closure of the urethrostomy site requires accurate apposition of mucosa to skin to reduce the risk of urine extravasation, inflammation...
Source: Advances in Small Animal Medicine and Surgery - January 1, 2018 Category: Veterinary Research Tags: Surgery (Soft Tissue) Source Type: research

Common Laboratory Abnormalities Caused by Paraneoplastic Syndrome
Paraneoplastic syndromes that cause abnormalities in hematologic and serum chemistry parameters often have a poor prognosis.1 Understanding the underlying pathogenic mechanisms of paraneoplastic syndromes can help direct treatment strategies and improve outcome. The purpose of this article is to summarize the current knowledge of mechanisms by which paraneoplastic syndromes affect complete blood count and serum chemistry profiles. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Authors: Amy L. Macneill Tags: Guest Editorial Source Type: research

Lung ultrasound B-lines in dogs with different stages of chronic valvular heart disease
Chronic valvular heart disease (CVHD) is the most common acquired cardiac disease in dogs. The disease is characterized by a progressive degeneration of the mitral valve, which leads to mitral regurgitation. Mitral regurgitation can lead to cardiac remodeling and development of congestive heart failure (CHF). Although most dogs with CVHD remain asymptomatic for years, approximately one-third develop CHF and die from their heart disease. Thus, both early recognition and prompt treatment of cardiac remodeling and CHF are of utmost clinical importance. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Cardiology Source Type: research

Mycophenolate mofetil treatment of immune-mediated skin disease in dogs
Mycophenolate mofetil (MMF) is an immunosuppressive agent used in human and companion animal medicine for the treatment of immune-mediated disease. In humans, it was initially approved for prevention of renal allograft rejection and its use has since expanded to several other immune-mediated diseases. In companion animals it has been prescribed for the treatment of multiple immune-mediated conditions including, but not limited to, hemolytic anemia, acquired myasthenia gravis, and pemphigus vulgaris. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Dermatology Source Type: research

Histopathologic characteristics of intestinal biopsy samples from dogs with chronic enteropathy with and without hypoalbuminemia
Chronic enteropathy (CE) is a term used to describe various inflammatory conditions of the intestinal tract. It is characterized by the presence of gastrointestinal (GI) signs such as weight loss, vomiting, diarrhea, and decreased appetite of at least several weeks duration and is associated with histologic evidence of inflammation in the small intestine. In dogs, the type of CE often is determined by response to treatment and can include antibiotic-responsive disease, food-responsive disease, and idiopathic inflammatory bowel disease, which may be steroid responsive. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Gastroenterology Source Type: research

Clinical features, imaging characteristics, and long-term outcome of dogs with cranial meningocele or meningoencephalocele
Malformations of the skull include incomplete closure of the calvaria. This opening of the cranium, termed cranioschisis, is a potential gap in the skull through which tissue can protrude. A meningoencephalocele (MEC) is a protrusion of cerebral tissue and meninges through a cranial defect, whereas a meningocele (MC) is a herniation of the meninges only. The prevalence of cranial MC and MEC in dogs currently is unknown, and there are only 4 case reports described. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Neurology Source Type: research

WHO histologic classification and clinical outcome in feline lymphoma
Lymphoma is the most frequent malignant tumor in cats. In the majority of cases, fine-needle aspiration of the suspicious tissue with subsequent cytology confirms the diagnosis. Quite often, this diagnosis is rendered adequate for starting an adjuvant therapy to treat “the lymphoma.” Valli et al. stated more than a decade ago that a simple lymphoma diagnosis is not sufficient for veterinary oncologists to provide optimal tumor management. Thus, to diagnose all possible lymphoma subtypes according to the established revised European-American Classification of Lymphoid Neoplasms/World Health Organization (REAL/WHO) class...
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Oncology Source Type: research

Safety of administering canine melanoma DNA vaccine to cats with malignant melanoma
Melanocytic tumors are relatively rare in cats. The primary sites affected most commonly are intraocular, periocular, and dermal sites, although other primary locations involving oral, nares, digit, and orbital lesions have been described. Malignant melanoma (MM) appears to have an aggressive local behavior and a high risk for dissemination in cats, regardless of the primary site of origin. Surgery and radiation therapy have been the primary modalities used for treatment of malignant melanoma in cats. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Oncology Source Type: research

Middle ear polyps: traction avulsion after a lateral approach to the ear canal
Middle ear polyps in cats are relatively common benign masses that arise from the mucosal lining of the middle ear, Eustachian tube, or the nasopharynx. Whereas many cats will not demonstrate any specific clinical signs associated with middle ear polyps, extension of the polyps beyond the boundaries of the middle ear leads to signs of otitis externa, otitis interna, or nasopharyngitis. Diagnosis of polyps is relatively straightforward when polyps have protruded into the ear canal or into the nasopharynx where they can easily be demonstrated using otoscopy and nasopharyngoscopy. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - December 1, 2017 Category: Veterinary Research Tags: Surgery (Soft Tissue) Source Type: research

Tick-Borne Diseases of the Cat
Ticks on domestic cats are often overlooked as vectors of infectious disease. There is a belief that cats are fastidious groomers and remove ticks before attachment takes place, resulting in insufficient time for transmission of infectious agents. Many cats live mainly indoors, causing owners to believe that their cats are not exposed to ticks.1 Feline vector-borne diseases (FVBD) have emerged in recent years, showing a wider global prevalence. Besides their veterinary importance, domestic cats play a central role in the transmission cycles of some FVBD agents as reservoirs and sentinels, an occurrence that requires a One ...
Source: Advances in Small Animal Medicine and Surgery - November 1, 2017 Category: Veterinary Research Authors: Remo Lobetti Tags: Guest Editorial Source Type: research

Relationships between onychectomy or technique and house soiling in cats
House soiling by pet cats is a substantial and multifactorial problem, with adverse effects on the human-animal bond. The problem is defined as defecating, urinating, or spraying urine outside of the litter box. Many cats with house-soiling behaviors are relinquished to animal shelters by their owners, where they are at risk of euthanasia. Therefore, a decrease in the prevalence of these behaviors could lead to a decrease in the prevalence of relinquishment of cats to animal shelters and their subsequent euthanasia. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - November 1, 2017 Category: Veterinary Research Tags: Behavior Source Type: research

The effect of heart disease on anesthetic complications during routine dental procedures in dogs
Heart disease is estimated to affect approximately 11% of the dog population, with 75 to 80% of canine heart disease classified as chronic valvular heart disease, also called endocardiosis. Periodontal disease is also common in dogs – potentially among the most common diseases of older dogs. The presence of heart disease in dogs requiring general anesthesia for dental treatment represents an important source of anxiety among both practicing veterinarians and pet owners. In some dogs afflicted with both heart and periodontal d isease, needed dental procedures are denied or delayed because of this fear. (Source: Advances i...
Source: Advances in Small Animal Medicine and Surgery - November 1, 2017 Category: Veterinary Research Tags: Cardiology Source Type: research

Cryptococcal maxillary osteomyelitis and osteonecrosis in an 18-month-old dog
Maxillary osteonecrosis in dogs has several etiologies reported in the veterinary literature. The presence of Cryptococcus subspecies, as either a primary or secondary infectious agent in canine maxillary osteonecrosis, is described in this report. It presents a new set of diagnostic, therapeutic, and public health challenges to the field of veterinary dentistry. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - November 1, 2017 Category: Veterinary Research Tags: Dentistry Source Type: research

Relationship between cholestatic disease and pituitary-dependent hyperadrenocorticism in dogs
Hyperadrenocorticism (HAC) is a common endocrine disease of dogs and is classi fied as pituitary-dependent hyperadrenocorticism (PDH), adrenal-dependent hyperadrenocorticism (ADH), or iatrogenic, depending on the cause of the excessive cortisol. Hyperadrenocorticism is characterized by variable clinical signs, and several medical complications may develop secondary to prolong ed excess of cortisol. Trilostane is a drug that is now used worldwide in dogs with HAC since its development as a veterinary product in 1998. (Source: Advances in Small Animal Medicine and Surgery)
Source: Advances in Small Animal Medicine and Surgery - November 1, 2017 Category: Veterinary Research Tags: Gastroenterology Source Type: research