Structure, Function and Insertion of the Human Vocal Folds.
Authors: Paulsen F, Tillmann B Abstract We here summarize the structures of the laryngeal vocal fold as well as its insertion structures at the anterior commissure and at the area of the vocal process and place these findings within the context of biomechanical, functional, and clinical implications. PMID: 33166982 [PubMed - in process] (Source: Advances in Oto-Rhino-Laryngology)
Source: Advances in Oto-Rhino-Laryngology - November 12, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Future Advances in Neurolaryngology.
Authors: Prasad VMN, Remacle M Abstract Neurolaryngology as a subspecialty of laryngology has developed considerably in the last four decades with more laryngologists, neurologists, speech and swallow therapists, and neurophysiologists taking interest in the field. The North American and Japanese laryngology societies have increasingly focused on conditions which are mainly concerned with aberrations of the nervous system affecting the larynx directly or indirectly. In the last few years, societies in Europe and the Asia-Pacific have also recognized the need to collaborate both within their organizations a...
Source: Advances in Oto-Rhino-Laryngology - November 12, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Preface.
Authors: Prasad VMN, Remacle M PMID: 33166984 [PubMed - in process] (Source: Advances in Oto-Rhino-Laryngology)
Source: Advances in Oto-Rhino-Laryngology - November 12, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Benign Tumors of the Anterior Cranial Base.
Authors: Snyderman CH, Lavigne P Abstract Benign tumors of the anterior cranial base may originate from intracranial, cranial, or extracranial sites. Intracranial tumors such as meningiomas may secondarily involve the cranial base and extend into the sinuses or nasal cavity. Bony tumors arising from the cranium include benign fibro-osseous lesions such as osteoma, fibrous dysplasia, and ossifying fibroma. The most common extracranial tumors that may extend to the skull base include angiofibroma and inverted papilloma. Symptoms are nonspecific and diagnosis is often delayed. In most cases, a diagnosis can b...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Endoscopic Endonasal Approaches for Anterior Skull Base Meningiomas.
Authors: Todeschini AB, Beer-Furlan A, Otto B, Prevedello DM, Carrau RL Abstract Anterior skull base meningiomas are a diverse group of tumors that involve different locations. The role of the expanded endoscopic transnasal approach in the management of anterior cranial fossa meningiomas has significantly changed over the past 2 decades. Patient selection is paramount to benefit from the advantages of endoscopic transnasal surgery such as direct access to ventral skull base lesions avoiding brain and brainstem retraction, early de-vascularization, removal of bone infiltrated by tumor, near-field magnificat...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Squamous Cell Carcinoma and Its Variants.
Authors: Mani N, Shah JP Abstract Squamous cell carcinoma (SCC) is one of the most common malignant neoplasms involving the anterior skull base, resulting from local invasion from an adjacent anatomical region. The primary sites of origin are most frequently the nasal cavity and paranasal sinuses, and less often the skin and orbit. Treatment strategies for these tumors have evolved, although management remains challenging due to the proximity to critical structures and their location at the intracranial-extracranial interface. The rarity of these tumors, and limited numbers at any one institution, has mean...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Other Rare Sinonasal Malignant Tumours Involving the Anterior Skull Base.
Authors: Naga R, Pai PS Abstract Sinonasal tumours are rare, and among these there exist a small number of histologic subtypes that are infrequently encountered and rarely mentioned in the literature. These have been presented as either case reports or small case series, and their very low incidence makes prospective studies practically impossible. This review analyses the available literature, including our own experience and endeavours to outline management strategies, which involve a high index of suspicion and counselling of patients. In most instances, these tumours require aggressive multimodal treat...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Posttreatment Imaging Surveillance.
Authors: Farina D, Zorza I, Golemi S, Lombardi D, Borghesi A, Maroldi R, Ravanelli M Abstract Posttreatment imaging surveillance in patients treated for anterior skull base tumors is a multifaceted issue which - as a first step - requires tailoring of the selection of imaging technique and acquisition protocol to the clinical scenario. As a general rule, acute symptoms suggesting the onset of a complication of treatment require prompt diagnosis through an easily accessible technique, such as CT; on the other hand, monitoring recurrences in asymptomatic patients is best achieved with MRI, exploiting the inh...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Treatment Options for Recurrent Anterior Skull Base Tumors.
Authors: Orlandi E, Iacovelli NA, Ingargiola R, Resteghini C, Bossi P, Licitra L, Ferrari M, Nicolai P Abstract Malignancies of the anterior skull base are rare and recur in 40-80% of treated cases, varying with substantial variance according to histology, stage at primary diagnosis, and other factors. Most recurrences manifest within 2-5 years after primary treatment, but some histologies can relapse even decades after the first presentation. Management of recurrent anterior skull base tumors is challenging and a wide variety of treatment options are available. Similar to the primary setting, surgery is t...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Future Perspectives in the Management of Tumors of the Anterior Skull Base.
Authors: Nicolai P, Bradley PJ, Bossi P, Ferrari M Abstract In the coming years, further developments can be expected in the field of diagnosis and management of tumors involving the anterior skull base, and especially malignant tumors of the sinonasal tract, which account for the majority of lesions affecting this anatomic area. Advances in genomics and radiomics will undoubtedly lead to better profiling of tumor biology, with consequent refinement of treatment according to the principles of precision medicine. Similarly, the continuous evolution of morphologic and metabolic imaging will improve the accur...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

A Comprehensive Update on Intestinal- and Non-Intestinal-Type Adenocarcinomas.
Authors: Vander Poorten V, Jorissen M Abstract This review of sinonasal adenocarcinoma, both intestinal and non-intestinal type, aims at providing a comprehensive overview of etiological factors, diagnostic workup, histological subtypes, advances in molecular characterization and the genetic basis, current optimal treatment strategies, resulting oncological outcome, and prognostic factors modifying the final treatment results. The current treatment of choice remains surgical resection with a curative intent, using the least invasive approach that allows for removal of the entire tumor with negative margins...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Olfactory Neuroblastoma.
Authors: Veyrat M, VĂ©rillaud B, Fiaux-Camous D, Froelich S, Bresson D, Nicolai P, Herman P Abstract Olfactory neuroblastoma is a rare tumor. Nasal endoscopy typically identifies a soft mass arising from the olfactory cleft. Computer tomography and magnetic resonance imaging are mandatory for staging (in association with 18F-fluorodeoxyglucose positron emission tomography) in high-grade and/or high-stage tumors. Biopsy must be representative to confirm a diagnosis and for grading purposes. Two complementary classifications are described: one (Kadish) based on clinical-radiological analysis, and the other (...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Pathology and Differential Diagnosis of Anterior Skull Base Tumours.
Authors: Williams MD, El-Naggar AK Abstract The anterior skull base is a complex anatomic site which may be involved by a large number of biologically heterogenous neoplasms. They arise from the epithelium, both surface mucosa and glands, as well as soft tissues, bone, and cartilage. Many benign and malignant tumours in the anterior skull base are similar to their counterparts in other anatomic sites. Interestingly, unique tumours including teratocarcinosarcoma, olfactory neuroblastoma, and angiofibroma can also be found. Recognition of overlapping morphologic features of entities encountered in this anato...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

The Role of Morphologic and Functional Imaging in Pretreatment Assessment.
Authors: Maroldi R, Borghesi A, Ravanelli M, Golemi S, Farina D Abstract Anterior skull base (ASB) tumors can be classified into three groups according to their site of origin: (1) sinonasal neoplasms involving or extending through the anterior cranial base; (2) neoplasms which arise from the bony framework of the base itself; (3) neoplasms originating from adjacent intracranial structures. With few exceptions, most of these tumors have a non-specific appearance on CT and MRI, which limits the role of imaging in terms of characterization. However, treatment planning (transnasal endoscopic surgery in partic...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research

Transnasal Endoscopic Surgery: Surgical Techniques and Complications.
Authors: Battaglia P, Lambertoni A, Castelnuovo P Abstract Nowadays, surgeons have a wide armamentarium of surgical approaches available to safely treat sinonasal malignancies, which includes open approaches, with the traditional craniofacial resection (CFR), and endoscopic transnasal techniques. The correct choice depends on the features of the pathology. It is well known that endoscopic approaches have a lower morbidity compared with traditional open techniques, due to a shorter hospitalization, absence of facial incisions, and avoidance of brain retraction. Moreover, endoscopic surgery presents clear te...
Source: Advances in Oto-Rhino-Laryngology - August 1, 2020 Category: ENT & OMF Tags: Adv Otorhinolaryngol Source Type: research