Preventing Hepatitis B in the Dialysis Unit
Publication date: May 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 3Author(s): Vivek Soi, Sandeep SomanPatients with end-stage renal disease are at risk for contracting hepatitis B virus (HBV) because of their exposure to blood products and compromised immune status. Despite a decrease in the incidence of HBV infection, continued vigilance in the form of surveillance is imperative in preventing the spread of this robust DNA virus. Regular review of serologic markers with isolation and decontamination practices as appropriate are paramount to maintaining a safe environment for dialysis to occur. Vaccinat...
Source: Advances in Chronic Kidney Disease - June 13, 2019 Category: Urology & Nephrology Source Type: research

The Changing Face of Human Immunodeficiency Virus-Mediated Kidney Disease
Publication date: May 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 3Author(s): Krishna Sury, Mark A. PerazellaIn nearly 40 years since human immunodeficiency virus (HIV) first emerged, much has changed. Our understanding of the pathogenesis of HIV infection and its effect on the cells within each kidney compartment has progressed, and the natural history of the disease has been transformed. What was once an acutely fatal illness is now a chronic disease managed with oral medications. This change is largely due to the advent of antiretroviral drugs, which have dramatically altered the prognosis and prog...
Source: Advances in Chronic Kidney Disease - June 13, 2019 Category: Urology & Nephrology Source Type: research

Flaviviruses and Kidney Diseases
Publication date: May 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 3Author(s): Emmanuel A. BurdmannThe genus Flavivirus comprises approximately 73 viruses, which share several common aspects, such as dimension, structure, nucleic acid properties, and shape in electronic microscopy. Global incidence of flavivirus infection increased dramatically over the last decades, causing large outbreaks in several areas of the world. These viruses are expanding from endemic tropical and subtropical areas to previously nonendemic areas, affecting and causing diseases in millions of individuals worldwide and posing a ...
Source: Advances in Chronic Kidney Disease - June 13, 2019 Category: Urology & Nephrology Source Type: research

Kidney Diseases Associated With Parvovirus B19, Hanta, Ebola, and Dengue Virus Infection: A Brief Review
Publication date: May 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 3Author(s): Narayan Prasad, James E. Novak, Manas R. PatelViral infection-associated kidney diseases are an emerging public health issue in both developing and developed countries. Many new viruses have emerged with new paradigms of kidney injury, either directly through their cytopathic effect or indirectly through immune-mediated glomerulopathy, tubulointerstitial disease, and acute kidney injury as part of multiorgan failure. Herein, we will discuss Parvovirus, which causes glomerulopathy, and Hanta, Ebola, and Dengue viruses, which c...
Source: Advances in Chronic Kidney Disease - June 13, 2019 Category: Urology & Nephrology Source Type: research

Masthead
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Editorial Board
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Table of Contents
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Dr. Conn Lives on: Insights Into Screening and Genetics of Primary Aldosteronism
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Debbie L. Stein, Jerry Yee (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Hypertension: A Common but Complex Condition
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Kausik Umanath (Source: Advances in Chronic Kidney Disease)
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Assessment of Blood Pressure: Techniques and Implications From Clinical Trials
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Dia R. Waguespack, Jamie P. DwyerHypertension is a global health problem and without adequate diagnosis and treatment is a risk factor for morbidity and mortality. Proper assessment of blood pressure is key to diagnosis and management of hypertension. Different methods of measurement are available for use and varying techniques are applied to patient care. Understanding the proper methods of blood pressure measurement both in and out of the physician's office is crucial for providing appropriate care to an individual patien...
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Ambulatory Blood Pressure Monitoring: Profiles in Chronic Kidney Disease Patients and Utility in Management
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Nabeel Aslam, Samardia Missick, William HaleyOptimal control of blood pressure (BP) may reduce the risk of progression of CKD. Misclassification of hypertension (HTN) and status of control may result in suboptimal management. Clinic or home BP may overestimate or underestimate status of control compared with ambulatory BP monitoring (ABPM), which is considered the gold standard. The latter relates not only to the superiority of ABPM concerning outcome prognosis but also to its ability to accurately diagnose white coat and m...
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Resistant Hypertension: Diagnosis and Management
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Nagalakshmi Nagarajan, Diana JalalResistant hypertension is defined as high blood pressure requiring 3 or more medications for adequate control or controlled blood pressure requiring 4 or more medications. Considering the growing prevalence of hypertension and the strong link with cardiovascular disease, it is vital to understand the causes and treatment of resistant hypertension. This review article starts with an overview of the prevalence and little-known pathophysiology of resistant hypertension. Afterward, we discuss t...
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

How Low Do We Go (in the Post-SPRINT Era)?
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Anna Burgner, Julia B. LewisHypertension is frequently both a cause and complication of CKD. The optimal blood pressure target in CKD has been of hot debate over the decades with little data to inform the goals. Here, we review the data from the Systolic Blood Pressure Intervention Trial (SPRINT), Modification of Diet in Renal Disease (MDRD), African American Study of Kidney Disease and Hypertension (AASK), Ramipril Efficacy in Nephropathy-2 (REIN-2), and Action to Control Cardiovascular Risk in Diabetes (ACCORD) trials to ...
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Treating Hypertension Using Renal Artery Denervation: Problems and Progress
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Raymond R. TownsendEarly reports of renal denervation as a therapy for hypertension generated intense interest in this approach to management of elevated blood pressures despite ongoing treatment. The publication of the large, sham-controlled randomized clinical trial of renal denervation, Symplicity HTN-3, failed to show superiority of renal denervation by radiofrequency energy ablation compared with a sham procedure similar to the procedure used for denervation but without the application of energy to the renal artery. Th...
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research

Inflammation, Immunity, and Oxidative Stress in Hypertension—Partners in Crime?
Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Ian R. Barrows, Ali Ramezani, Dominic S. RajHypertension is considered as the most common risk factor for cardiovascular disease. Inflammatory processes link hypertension and cardiovascular disease, and participate in their pathophysiology. In recent years, there has been an increase in research focused on unraveling the role of inflammation and immune activation in development and maintenance of hypertension. Although inflammation is known to be associated with hypertension, whether inflammation is a cause or effect of hyp...
Source: Advances in Chronic Kidney Disease - April 24, 2019 Category: Urology & Nephrology Source Type: research