Inhibition of USP7 enhances CD8+ T cell activity in liver cancer by suppressing PRDM1-mediated FGL1 upregulation
Acta Pharmacologica Sinica, Published online: 08 April 2024; doi:10.1038/s41401-024-01263-2Inhibition of USP7 enhances CD8+ T cell activity in liver cancer by suppressing PRDM1-mediated FGL1 upregulation (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 8, 2024 Category: Drugs & Pharmacology Authors: Lin-lin Sun Li-na Zhao Jiao Sun Hong-feng Yuan Yu-fei Wang Chun-yu Hou Pan Lv Hui-hui Zhang Guang Yang Ning-ning Zhang Xiao-dong Zhang Wei Lu Source Type: research
Exosomes derived from induced cardiopulmonary progenitor cells alleviate acute lung injury in mice
Acta Pharmacologica Sinica, Published online: 08 April 2024; doi:10.1038/s41401-024-01253-4Exosomes derived from induced cardiopulmonary progenitor cells alleviate acute lung injury in mice (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 8, 2024 Category: Drugs & Pharmacology Authors: Luo-xing Xia Ying-ying Xiao Wen-jing Jiang Xiang-yu Yang Hua Tao Safur Rehman Mandukhail Jian-feng Qin Qian-rong Pan Yu-guang Zhu Li-xin Zhao Li-juan Huang Zhan Li Xi-yong Yu Source Type: research
Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway
Acta Pharmacologica Sinica, Published online: 08 April 2024; doi:10.1038/s41401-024-01265-0Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 8, 2024 Category: Drugs & Pharmacology Authors: Xia-yun Ni Xiao-jun Feng Zhi-hua Wang Yang Zhang Peter J. Little Yang Cao Suo-wen Xu Li-qin Tang Jian-ping Weng Source Type: research
Neutrophil extracellular traps promote acetaminophen-induced acute liver injury in mice via AIM2
Acta Pharmacologica Sinica, Published online: 08 April 2024; doi:10.1038/s41401-024-01239-2Neutrophil extracellular traps promote acetaminophen-induced acute liver injury in mice via AIM2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 8, 2024 Category: Drugs & Pharmacology Authors: Fan-le Zeng Yuan Zhang Zhong-hao Wang Hui Zhang Xue-teng Meng Yi-qin Wu Zhen-zhen Qian Yu-hao Ding Jun Li Tao-tao Ma Cheng Huang Source Type: research
A novel role of PSMB9 in endothelial cells and atherosclerosis: beyond its canonical function in immunoproteasome
Acta Pharmacol Sin. 2024 Apr 3. doi: 10.1038/s41401-024-01267-y. Online ahead of print.NO ABSTRACTPMID:38570600 | DOI:10.1038/s41401-024-01267-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Xiaolei Liu Esteban Delgado Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
A novel role of PSMB9 in endothelial cells and atherosclerosis: beyond its canonical function in immunoproteasome
Acta Pharmacol Sin. 2024 Apr 3. doi: 10.1038/s41401-024-01267-y. Online ahead of print.NO ABSTRACTPMID:38570600 | DOI:10.1038/s41401-024-01267-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Xiaolei Liu Esteban Delgado Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
A novel role of PSMB9 in endothelial cells and atherosclerosis: beyond its canonical function in immunoproteasome
Acta Pharmacol Sin. 2024 Apr 3. doi: 10.1038/s41401-024-01267-y. Online ahead of print.NO ABSTRACTPMID:38570600 | DOI:10.1038/s41401-024-01267-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Xiaolei Liu Esteban Delgado Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
A novel role of PSMB9 in endothelial cells and atherosclerosis: beyond its canonical function in immunoproteasome
Acta Pharmacol Sin. 2024 Apr 3. doi: 10.1038/s41401-024-01267-y. Online ahead of print.NO ABSTRACTPMID:38570600 | DOI:10.1038/s41401-024-01267-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Xiaolei Liu Esteban Delgado Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
A novel role of PSMB9 in endothelial cells and atherosclerosis: beyond its canonical function in immunoproteasome
Acta Pharmacol Sin. 2024 Apr 3. doi: 10.1038/s41401-024-01267-y. Online ahead of print.NO ABSTRACTPMID:38570600 | DOI:10.1038/s41401-024-01267-y (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Xiaolei Liu Esteban Delgado Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
In conclusion, the pharmacokinetics and pharmacodynamics of morphine and M6G, antagonistic effects of naloxone against morphine-induced CNS effects may be successfully predicted using the developed PBPK-PD model based on the parameters derived from in vitro, in silico, or animal studies.PMID:38570601 | DOI:10.1038/s41401-024-01255-2 (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-Jing Mu Tian-Lei Liu Xiao-Dong Liu Li Liu Source Type: research
PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans
Acta Pharmacologica Sinica, Published online: 03 April 2024; doi:10.1038/s41401-024-01255-2PBPK-PD model for predicting morphine pharmacokinetics, CNS effects and naloxone antagonism in humans (Source: Acta Pharmacologica Sinica)
Source: Acta Pharmacologica Sinica - April 3, 2024 Category: Drugs & Pharmacology Authors: Rui-jing Mu Tian-lei Liu Xiao-dong Liu Li Liu Source Type: research
