Early hydrocortisone improves survival without bronchopulmonary dysplasia in extremely preterm born infants
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 29, 2017 Category: Pediatrics Authors: Alexander Rakow, Mikael Norman Tags: EBNEO Commentary Source Type: research

Families ’ perceived benefits of home visits for managing paediatric obesity outweigh the potential costs and barriers
ConclusionFamilies felt home visits were a convenient option for managing paediatric obesity and identified important benefits and barriers that could guide such interventions.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 28, 2017 Category: Pediatrics Authors: Nicole D. Gehring, Geoff D.C. Ball, Arnaldo Perez, Nicholas L. Holt, Daniel Neuman, Nicholas Spence, Laura Mercier, Mary Jetha Tags: Regular Article Source Type: research

Arterial catheterisation in neonates can result in severe ischaemic complications but does not impair long ‐term extremity function
ConclusionSevere ischaemic complications in neonates following arterial catheterisation were rare events, but could cause devastating damage. Most patients didn't show impaired extremity function at follow up.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 28, 2017 Category: Pediatrics Authors: Philipp Deindl, Thomas Waldh ör, Lukas Unterasinger, Angelika Berger, Maike Keck Tags: Regular Article Source Type: research

High ‐sensitivity C‐reactive protein concentration in young adults in the Helsinki Study of Very Low Birth Weight Adults
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 28, 2017 Category: Pediatrics Authors: Kai Yin Ho, Rie Goto, Pieta N äsänen‐Gilmore, Sture Andersson, Johan G. Eriksson, Eero Kajantie, Petteri Hovi Tags: Short Communication Source Type: research

Near ‐infrared spectroscopy is a promising non‐invasive technique for monitoring the effects of feeding regimens on the cerebral and splanchnic regions
Abstract AimThe effects of different milk and, or, administration regimens on cerebro‐splanchnic perfusion are still a matter of debate. We investigated the effects of the bolus administration of breast milk or formula on cerebro‐splanchnic oximetry, function and perfusion, assessed by near‐infrared spectroscopy (NIRS). MethodsThis observational study of 30 infants fed with breast (n=15) or formula (n=15) milk, and matched for gestational age and birth weight, was carried out in the neonatal intensive care unit of the C Arrigo Children's Hospital, Alessandria, Italy, a tertiary level referral centre, from October 201...
Source: Acta Paediatrica - September 27, 2017 Category: Pediatrics Authors: Alice Grometto, Benedetta Pizzo, Maria Chiara Strozzi, Francesca Gazzolo, Diego Gazzolo Tags: Regular Article Source Type: research

Low age, low birthweight and congenital heart disease are risk factors for intensive care in infants with bronchiolitis
This study evaluated the incidence and risk factors for intensive care and respiratory support in infant bronchiolitis. MethodsThis retrospective descriptive case–control study focused on 105 patients treated in the paediatric intensive care unit (PICU) and 210 controls treated in the emergency department or on the paediatric ward in Tampere University Hospital in Finland between 2000 and 2015. Statistically significant risk factors in nonadjusted analyses were included in the adjusted logistic regression. ResultsThe average age‐specific annual incidence of bronchiolitis requiring PICU admission under the age of 12...
Source: Acta Paediatrica - September 27, 2017 Category: Pediatrics Authors: Minna Mecklin, Paula Heikkil ä, Matti Korppi Tags: Regular Article Source Type: research

Investigation and management of gastro ‐oesophageal reflux in United Kingdom neonatal intensive care units
ConclusionThere remains a wide variation in diagnostic and treatment strategies for infants with suspected GOR on neonatal intensive care units, emphasising the need for randomised trials to determine appropriate GOR management. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 27, 2017 Category: Pediatrics Authors: Thomas Rossor, Gwendolyn Andradi, Ravindra Bhat, Anne Greenough Tags: Regular Article Source Type: research

Parents spend an average of nine hours a day providing palliative care for children at home and need to maintain an average of five life ‐saving devices
ConclusionParents providing palliative care for children with life‐limiting diseases spent an average of nine hours a day caring for them each day and had to maintain an average of five medical appliances.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 25, 2017 Category: Pediatrics Authors: P. Lazzarin, B. Schiavon, L. Brugnaro, F. Benini Tags: Regular Article Source Type: research

Marshall H. Klaus M.D., A Life Sketch
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 25, 2017 Category: Pediatrics Authors: Avroy A. Fanaroff Tags: Obituary Source Type: research

Treatment methods for respiratory syncytial virus bronchiolitis need to be evaluated before they are introduced on a large scale
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 25, 2017 Category: Pediatrics Authors: Bill Hesselmar Tags: Editorial Source Type: research

Symptom management and psychological support for families are the cornerstones of end ‐of‐life care for children with spinal muscular atrophy type 1
ConclusionOur study found that symptom management and psychological support for families were the cornerstones of end‐of‐life care for children with SMA1.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 23, 2017 Category: Pediatrics Authors: Chiara Di Pede, Caterina Agosto, Valentina De Tommasi, Alessandra De Gregorio, Franca Benini Tags: Regular Article Source Type: research

Performing a urine dipstick test with a clean ‐catch urine sample is an accurate screening method for urinary tract infections in young infants
ConclusionPerforming urine dipstick tests using urine samples obtained by the clean‐catch method was an accurate screening test for diagnosing UTIs in febrile infants of less than 90 days old. This provided a good alternative to bladder catheterisation when screening for UTIs.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 23, 2017 Category: Pediatrics Authors: Mar ía Luisa Herreros, Alfredo Tagarro, Araceli García‐Pose, Aida Sánchez, Alfonso Cañete, Pablo Gili Tags: Regular Article Source Type: research

Assessing bone development in preterm infants using quantitative ultrasonography showed a decline in the early postnatal period
ConclusionThe mcSOS and mcBTT of preterm infants showed a small to moderate decline during the early postnatal period. Future studies should explore the clinical relevance of this decline and develop interventions to halt it.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 22, 2017 Category: Pediatrics Authors: Marieke Krikke, Dana Yumani, Christine Rustenburg, Anneke Cranendonk, Jos Twisk, Harrie Lafeber, Mirjam Weissenbruch Tags: Regular Article Source Type: research

Using the Sophia Observational Withdrawal Scale improved the assessment of paediatric iatrogenic withdrawal symptoms
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 22, 2017 Category: Pediatrics Authors: Bettina N. Nielsen, Ulrikka Nygaard, Lise Hvidt, Kaare Lundstr øm Tags: Brief Report Source Type: research

Respiratory morbidity was an important consequence of prematurity in the first two years after discharge in three cohorts from 1996 ‐2009
ConclusionThis study showed that when cohorts of preterm infants were compared over time, respiratory morbidity in the first two years of life remained an important consequence after discharge.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 21, 2017 Category: Pediatrics Authors: Estelle E M Mulder, Monique Rijken, Lotte Smet, Steffen Pauws, Enrico Lopriore, Arjan B te Pas Tags: Regular Article Source Type: research

Number needed to suffer?
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 21, 2017 Category: Pediatrics Authors: Keith Barrington Tags: Letter Source Type: research

The Internet Game Use ‐Elicited Symptom Screen proved to be a valid tool for adolescents aged 10‐19 years
ConclusionThe findings suggest that a cut‐off score of 10 is appropriate for administering the IGUESS in various community‐based settings, including schools, to screen for potential subjects in need of further assessment for Internet gaming problems.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 21, 2017 Category: Pediatrics Authors: Sun ‐Jin Jo, Hyeon Woo Yim, Hae‐Kook Lee, Hyung Cho Lee, Jung‐Seok Choi, Kyung‐Young Baek Tags: Regular Article Source Type: research

Music exposure and maturation of late preterm sleep ‐wake cycles: A randomized crossover trial
ConclusionMusic exposure elicits an increasing PCA pattern in active sleep and fewer interruptions in quiet sleep. Music may benefit sleep in late preterm infants.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Authors: Adia Stokes, Alexander G. Agthe, Dina El Metwally Tags: Regular Article Source Type: research

Implementing higher oxygen saturation targets reduced the impact of poor weight gain as a predictor for retinopathy of prematurity
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Source Type: research

Music exposure and maturation of late preterm sleep –wake cycles: a randomised crossover trial
Acta Paediatrica,Volume 107, Issue 4, Page 582-586, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Source Type: research

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Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Source Type: research

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Acta Paediatrica,Volume 107, Issue 4, Page 582-586, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Source Type: research

Response Letter to ‘Optimising physiology for adolescents with dysautonomia’
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Authors: KR Armstrong, AM De Souza, PL Sneddon, JE Potts, VE Claydon, S Sanatani Tags: Reader's Forum Source Type: research

Nonpublication and discontinuation of randomised controlled trials in newborns
ConclusionNonpublication and discontinuation of RCTs conducted in newborns is common. Additional efforts are needed to minimise the number of neonatal trial participants that are exposed to interventions without subsequent publication. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 20, 2017 Category: Pediatrics Authors: Christoph M. R üegger, Jennifer A. Dawson, Susan M. Donath, Louise S. Owen, Peter G. Davis Tags: Regular Article Source Type: research

Evaluation of neonatal transport in a European country shows that regional provision is not cost ‐effective or sustainable and needs to be re‐organised
ConclusionItalian NETS, which is managed on the basis of regional decisional autonomy, is expensive and no longer sustainable in this era of limited financial resources. A complete overhaul is urgently needed.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 19, 2017 Category: Pediatrics Authors: Carlo Bellini, Michela Pasquarella, Luca A. Ramenghi, Daniela Ambrosino, Anna F. Sciomachen Tags: Regular Article Source Type: research

Follow ‐up protocol was useful for children whose parents attended emergency departments after partner violence, substance abuse or a suicide attempt
ConclusionThe Amsterdam protocol was valuable in referring families to voluntary support services, but given the on‐going problems in some families, professionals need to carefully monitor whether support services are sufficiently effective.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 19, 2017 Category: Pediatrics Authors: Eva M. M. Hoytema van Konijnenburg, Maj Gigengack, Arianne H. Teeuw, Tessa Sieswerda ‐Hoogendoorn, Sonja N. Brilleslijper‐Kater, Boudien C. Flapper, Ramón J. L. Lindauer, Johannes B. van Goudoever, Johanna H. Lee, Tags: Regular Article Source Type: research

Sex and maturity status affected the validity of a submaximal cycle test in adolescents
ConclusionThe EB test was reasonably valid in adolescents, seemed to be related to sex and maturity status and our findings support its use.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 19, 2017 Category: Pediatrics Authors: Frida Bj örkman, Andrea Eggers, Adam Stenman, Tony Bohman, Björn Ekblom, Örjan Ekblom Tags: Regular Article Source Type: research

Persistent pain in neonates: challenges in assessment without the aid of a clinical tool
ConclusionPain assessment is challenging for staff. Most parents feel confident in assessing their babies’ comfort, but may overestimate the ease with which staff can do so. Indicators of persistent pain/comfort are poorly defined; staff use differing, subjective assessments, which may complicate communication between carers.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 19, 2017 Category: Pediatrics Authors: Elaine M Boyle, Joanna Bradshaw, Kathryn I Blake Tags: Regular Article Source Type: research

National allergy programme had little impact on parent ‐reported food allergies in children aged 6‐7 years
ConclusionWe studied the national allergy programme that started in 2008 and found that there was a non‐significant overall decrease in the number of children aged 6‐7 on avoidance diets for allergies between 2009‐2016. The only allergies that showed signficiant decreases were fresh fruit and vegetables.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 19, 2017 Category: Pediatrics Authors: Sauli Palmu, Paula Heikkil ä, Virpi Uski, Siina Niitty, Sari Kurikka, Matti Korppi Tags: Regular Article Source Type: research

Observational study shows that nurses spend more time caring for  mechanically ventilated preterm infants than those receiving noninvasive ventilation
ConclusionInvasive support was associated with higher workloads than noninvasive support. The differences were partially moderated by individual factors, such as the infant's age. The findings should be replicated within a multicentre design. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 17, 2017 Category: Pediatrics Authors: Kristina Langhammer, Sandra S ülz, Michael Becker‐Peth, Bernhard Roth Tags: Regular Article Source Type: research

It's all in the genes... well almost
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 17, 2017 Category: Pediatrics Authors: G öran Wennergren Tags: Editorial Source Type: research

Outcomes of infants with a birthweight less than or equal to 500 g in Northern England: 15 years experience
ConclusionSurvival of babies born weighing ≤500 g in this cohort remains poor despite advances in neonatal care, with considerable short‐term neonatal morbidity in survivors. This could be due to a combination of attitudes and a rather conservative approach towards resuscitation and intensive care, and the intrinsic nature of these tiny babies. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 17, 2017 Category: Pediatrics Authors: Jenna Gillone, Nishant Banait, Nicola Miller, Martin Ward Platt, Sundeep Harigopal Tags: Regular Article Source Type: research

Preterm infants with necrotising enterocolitis demonstrate individual and unbalanced gut microbiota
ConclusionThe NEC infants were poorly colonised with no more than seven species and the controls had a more diversified and balanced gut microbiota. Understanding NEC aetiology better could lead to more effective prophylactic interventions and a reduced incidence.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 16, 2017 Category: Pediatrics Authors: Itani Tarek, Ayoub Moubareck Carole, Melki Imad, Rousseau Clotilde, Mangin Ir ène, Butel Marie‐José, Karam Sarkis Dolla Tags: Regular Article Source Type: research

Reporting anxiety symptoms in extremely preterm born adolescents and by their mothers
Abstract AimTo compare anxiety symptoms in adolescents born extremely prematurely to term‐born controls. MethodsWe had 96 preterm‐born adolescents and 40 term‐born controls from Denmark and their mothers score the adolescents on the Revised Children Anxiety and Depression scale. We analysed group differences, cross‐informant correlations, and relative risks for elevated anxiety symptoms. ResultsSelf‐reported anxiety symptoms did not significantly differ, although the upper confidence limit (95% CI [‐3.3 to 5.1]) supported an odds ratio of 2 for the preterm‐born participants. Mothers of the preterm‐born part...
Source: Acta Paediatrica - September 16, 2017 Category: Pediatrics Authors: M J S ømhovd, B H Esbjørn, B M Hansen, G Greisen Tags: Regular Article Source Type: research

National survey on managing minor childhood traumatic head injuries in The Netherlands shows low guideline adherence and large inter ‐hospital variations
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 16, 2017 Category: Pediatrics Authors: Nicky Niele, Lonneke Willemars, Marlies Houten, Frans B. Pl ötz Tags: Brief Report Source Type: research

Are men monkeys? Why are child healthcare professionals reluctant to include fathers in parenting support interventions?
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 15, 2017 Category: Pediatrics Authors: Malin Bergstr öm Tags: Editorial Source Type: research

Using probiotics to prevent necrotising enterocolitis
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 15, 2017 Category: Pediatrics Authors: Thomas R. Abrahamsson Tags: Editorial Source Type: research

Response Letter to “Optimising physiology for adolescents with dysautonomia”
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 14, 2017 Category: Pediatrics Authors: K Armstrong, A M De Souza, P Sneddon, J E Potts, V E Claydon, S Sanatani Tags: Letter Source Type: research

Investigation and management of gastro ‐oesophageal reflux in United Kingdom neonatal intensive care units
ConclusionThere remains a wide variation in diagnostic and treatment strategies for infants with suspected GOR on neonatal intensive care units, emphasizing the need for randomised trials to determine appropriate GOR management.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 13, 2017 Category: Pediatrics Authors: Thomas Rossor, Gwendolyn Andradi, Ravindra Bhat, Anne Greenough Tags: Regular Article Source Type: research

Response to Mortazavi's comment
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 13, 2017 Category: Pediatrics Authors: Bellieni Carlo Valerio, Giuseppe Buonocore Tags: Letter Source Type: research

Nutritional support in paediatric Crohn's disease; Outcome at 12 months
Abstract AimPaediatric Crohn's disease (CD) is associated with growth delay and poor nutritional status. Maintenance enteral nutrition (MEN) supplementation is a potential adjunct to improve growth/prolong remission. MethodsNewly‐diagnosed CD patients were identified. Anthropometry, treatments and outcomes were collected for 12 months following diagnosis. Data are presented as medians. Results102 patients were identified (age=13 years, 76% male), 58(57%) completed exclusive enteral nutrition (EEN) as induction therapy, 77(75%) entered clinical remission. Following induction 58(57%) of all patients continued MEN and 44(43...
Source: Acta Paediatrica - September 13, 2017 Category: Pediatrics Authors: J Gavin, JJ Ashton, N Heather, L V Marino, R M Beattie Tags: Regular Article Source Type: research

Establishing a regional paediatric registry improved the overview and detection of side effects in children on anticoagulants
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 12, 2017 Category: Pediatrics Authors: Ida Jeremiasen, Katarina Hans éus, Pernilla Naumann, Camilla Nilsson, Ulf Tedgård, Peter J. Svensson, Nadine G. Andersson Tags: Brief Report Source Type: research

Staff perceptions of challenging parent –staff interactions and beneficial strategies in the Neonatal Intensive Care Unit
ConclusionThis study delineates what staff perceive as challenging interactions and provides support for an educational and interventional role that incorporates mental health professionals. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 12, 2017 Category: Pediatrics Authors: Joshua Friedman, Susan Hatters Friedman, Marc Collin, Richard J. Martin Tags: Regular Article Source Type: research

Neural breathing pattern in newborn infants pre ‐ and postextubation
ConclusionIn our neonatal cohort, extubation failure was associated with a smaller increase in peak and delta EAdi after extubation. If confirmed, these findings indicate an important cause of extubation failure in preterm infants. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 12, 2017 Category: Pediatrics Authors: Narayan P. Iyer, John Dickson, Michelle E. Ruiz, Robert Chatburn, Jennifer Beck, Chister Sinderby, Ricardo J. Rodriguez Tags: Regular Article Source Type: research

Skin ‐to‐skin back transfers provide a feasible, safe and low‐stress alternative to conventional neonatal transport
This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 12, 2017 Category: Pediatrics Authors: Yves Hennequin, Laurence Grevesse, Delphine Gylbert, Val érie Albertyn, Sebastian Hermans, Bart Van Overmeire Tags: Brief Report Source Type: research

Urinary prostaglandin D2 metabolite excretion during the first six months of life was significantly lower in breast ‐fed than formula‐fed infants
ConclusionOur study showed that the type of feeding in early infancy affected prostaglandin metabolism in healthy term infants.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 12, 2017 Category: Pediatrics Authors: Hiromichi Shoji, Naho Ikeda, Tomohiro Kitamura, Hiroki Suganuma, Mai Ohba, Toshiaki Okuno, Takehiko Yokomizo, Toshiaki Shimizu Tags: Regular Article Source Type: research

Physical activity may decrease the likelihood of children developing constipation
ConclusionConstipation risk factors varied with age and many children diagnosed with constipation had recurrent symptoms. Physical activity may affect the likelihood of developing constipation in older children.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 12, 2017 Category: Pediatrics Authors: Sandra Seidenfaden, Orri Thor Ormarsson, Sigrun H Lund, Einar S Bjornsson Tags: Regular Article Source Type: research

Failing to meet relative humidity targets for incubated neonates causes higher heat loss and metabolic costs in the first week of life
This study evaluated the impact of relative humidity on preterm infants in closed incubators and calculated their heat loss and additional metabolic cost. MethodsWe studied 45 preterm infants born before 32+0 weeks, nursed at the neonatal intensive care unit at Amiens University Hospital, France from January 2009 to November 2011. Their body, skin and air temperatures and the incubator's relative humidity were continuously recorded from days 1‐8 of life and the differences between the measured and target relative humidity were calculated. Body heat loss was also calculated. ResultsOn day one, the measured relative humidi...
Source: Acta Paediatrica - September 7, 2017 Category: Pediatrics Authors: Romain Erbani, Lo ïc Dégrugilliers, Armand Lahana, Anaïs Glusko‐Charlet, Elodie Haraux, Estelle Durand, Pierre Tourneux Tags: Regular Article Source Type: research

Preschool children living in joint physical custody arrangements show less psychological symptoms than those living mostly or only with one parent
ConclusionJoint physical custody arrangements were not associated with more psychological symptoms in children aged 3–5, but longitudinal studies are needed to account for potential preseparation differences. (Source: Acta Paediatrica)
Source: Acta Paediatrica - September 7, 2017 Category: Pediatrics Authors: Malin Bergstr öm, Emma Fransson, Helena Fabian, Anders Hjern, Anna Sarkadi, Raziye Salari Tags: Regular Article Source Type: research

The care of a child with a newly diagnosed immune thrombocytopenia
(Source: Acta Paediatrica)
Source: Acta Paediatrica - September 6, 2017 Category: Pediatrics Authors: Rolf Ljung Tags: Editorial Source Type: research