---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 19, 2018 Category: Pediatrics Source Type: research

Wrapping newborn infants in cloth and newspaper after delivery led to higher temperatures on arrival at the neonatal intensive care unit
Abstract AimNeonatal hypothermia is a preventable cause of neonatal mortality and morbidity, and wrapping neonates in newspaper sandwiched between cotton sheets is a simple intervention. This 2017 Indian pilot study tested the heat insulating property of sandwiched sheets. MethodsAt birth, we randomised 100 neonates who were more than 32 weeks of gestation and needed neonatal intensive care unit (NICU) observation or care without a ventilator or bilevel positive airway pressure support into two groups of 50. The intervention and control groups were wrapped in two prewarmed sheets at birth that did or did not contain a laye...
Source: Acta Paediatrica - January 19, 2018 Category: Pediatrics Authors: Nitika Agrawal, Kunal Das, Prachi Patwal, Neerul Pandita, Alpa Gupta Tags: Regular Article Source Type: research

Wheat oral immunotherapy was moderately successful but was associated with very frequent adverse events in children aged 6 ‐18 years
ConclusionThe majority (57%) of children with wheat allergies could use wheat in their daily diet 16 months after the initiation of oral immunotherapy, but 94/100 had adverse reactions and 60 were moderate or severe. Specific immunoglobulin E to omega‐5‐gliadin may provide a biomarker for how much wheat can be tolerated and the intensity of the reactions to immunotherapy.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Authors: Petri Kulmala, Anna S Pelkonen, Mikael Kuitunen, Marita Paassilta, Sami Remes, R üdiger Schultz, Teija Dunder, Sami Turunen, Mika J. Mäkelä Tags: Regular Article Source Type: research

Systematic review and meta ‐analysis found higher levels of behavioural problems in male left‐behind children aged 6–11 years
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Source Type: research

Extreme prematurity, treated retinopathy, bronchopulmonary dysplasia and cerebral palsy are significant risk factors for ophthalmological abnormalities at 6.5  years of age
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Source Type: research

Systematic review and meta ‐analysis found higher levels of behavioural problems in male left‐behind children aged 6–11 years
ConclusionInterventions and policies are urgently needed to tackle behavioural issues among LBC, especially high‐risk males aged 6–11 years. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Authors: Guang ‐Bo Qu, Wei Wu, Ling‐Ling Wang, Xue Tang, Ye‐Huan Sun, Jie Li, Jun Wang Tags: Review Article Source Type: research

Aetiology of neonatal conjunctivitis evaluated in a population ‐based setting
ConclusionChlamydia trachomatis was a rare pathogen in neonatal conjunctivitis in a population‐based setting, but respiratory viruses were detected more frequently than indicated earlier.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Authors: Minna Honkila, Marjo Renko, Irma Ik äheimo, Tytti Pokka, Matti Uhari, Terhi Tapiainen Tags: Regular Article Source Type: research

Evaluation of bowel function in healthy children ‐ untreated constipation is common
ConclusionHealthy children frequently reported constipation, abdominal pain and gas‐related problems, but treatment was rare. Overall, bowel function seemed to improve during childhood, although constipation remained largely untreated.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 18, 2018 Category: Pediatrics Authors: Helena Lindgren, Malin Carvalho Nejstgaard, Martin Sal ö, Pernilla Stenström Tags: Regular Article Source Type: research

Painful procedures can affect postnatal growth and neurodevelopment in preterm infants
Abstract AimThis Italian study evaluated whether painful procedures during the first four weeks of life were related to subsequent weight gain, head circumference (HC) and neurodevelopmental outcomes in preterm infants, MethodsWe evaluated the number of invasive procedures that infants born at less than 32 weeks of gestational age (GA) underwent in the Neonatal Intensive Care Unit of Careggi Hospital, Florence from January to December 2015. Weight and HC were recorded at birth, 36 weeks of PMA and six and 12 months of CA. Neurological outcomes were assessed at six and 12 months of CA using the Bayley Scales of Infant and T...
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Authors: Caterina Coviello, Marina Popple Martinez, Livia Drovandi, Corsini Iuri, Valentina Leonardi, Clara Lunardi, Carla Antonelli, Simone Pratesi, Carlo Dani Tags: Regular Article Source Type: research

Study of top ballet school students revealed large deficiencies in their body weight and body fat
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Source Type: research

Association of intralipid intake in extremely low birthweight infants with  neurodevelopmental outcomes
ConclusionHigher IL intake was associated with lower cognitive, motor and language scores. Breast milk intake eliminated the latter associations, which underscores the important role of breast milk in developmental outcome. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Authors: William Oh, Lynn Przystac, Leslie McKinley, Richard Tucker, Elisabeth C. McGowan, Betty R. Vohr Tags: Regular Article Source Type: research

A case report and literature review of autism and attention deficit hyperactivity disorder in paediatric chronic pain
Conclusion: The inclusion of behavioural assessment and screening for neurodevelopmental comorbidity may be essential in addressing complex paediatric chronic pain. This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Authors: Camilla Wiwe Lipsker, Margareta Heijne, Sven B ölte, Rikard K. Wicksell Tags: Clinical Overview Source Type: research

Review shows that early fetal alcohol exposure may cause adverse effects even when the mother consumes low levels
ConclusionEven low levels of PAE can cause adverse fetal effects and not just in the brain. It is not currently possible to determine a safe period and level when alcohol consumption won't affect the fetus.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Authors: Ihsan Sarman Tags: Mini Review Source Type: research

Interaction between healthcare professionals and parents is a key determinant of parental distress during childhood hospitalisation for respiratory syncytial virus infection (European RSV Outcomes Study [EROS])
ConclusionThe relationship between parents and healthcare professionals was a significant factor in determining parental distress. Healthcare professionals appeared to have a good understanding of the overall impact on parents, particularly the key medical factors.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Authors: Xavier Carbonell ‐Estrany, Alberto Dall'Agnola, John R. Fullarton, Barry S. Rodgers‐Gray, Elisa Girardi, Alessandro Mussa, Natalia Paniagua, Marta Pieretto, Rosa Rodríguez‐Fernandez, Paolo Manzoni Tags: Regular Article Source Type: research

The five ‐year survival of children with Down syndrome in Norway 1994‐2009 differed by associated congenital heart defects and extracardiac malformations
ConclusionDown syndrome childhood survival improved, but mortality remained high with severe heart defects and extracardiac defects.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 17, 2018 Category: Pediatrics Authors: Kristoffer Brodwall, Gottfried Greve, Elisabeth Leirgul, Kari Klungs øyr, Henrik Holmstrøm, Stein Emil Vollset, Nina Øyen Tags: Regular Article Source Type: research

The Changing Relationship between Bronchopulmonary Dysplasia and Cognition in Very Preterm Infants
Abstract AimTo characterize the relationship between bronchopulmonary dysplasia (BPD) severity and cognition in the post‐surfactant era. MethodsThis was a single‐center retrospective analysis of a cohort of infants born 2009–2012. Inclusion criteria were: admission within 48 hours of birth, gestational age 22‐0/7–31‐6/7 weeks, birth weight 400–1500 g, and Bayley Scales of Infant and Toddler Development‐III testing at 18‐26 months corrected age. Infants (n=151) were classified by BPD severity with the NIH Workshop definition. Generalized linear modeling and multivariate logistic regression were...
Source: Acta Paediatrica - January 15, 2018 Category: Pediatrics Authors: Jane E. Brumbaugh, Tarah T. Colaizy, Neel M. Patel, Jonathan M. Klein Tags: Regular Article Source Type: research

Cryopyrin ‐associated periodic syndrome in early childhood can be successfully treated with interleukin‐1 blockades
ConclusionWhen CAPS has been diagnosed, an IL‐1 blockade with biologicals should be introduced to lessen the symptoms and to prevent the progression of organ damage.This article is protected by copyright. All rights reserved. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 13, 2018 Category: Pediatrics Authors: Vesa Eskola, Heini Pohjankoski, Liisa Kr öger, Kristiina Aalto, Katariina Latva, Matti Korppi Tags: Clinical Overview Source Type: research

Cryopyrin ‐associated periodic syndrome in early childhood can be successfully treated with interleukin‐1 blockades
Acta Paediatrica,Volume 107, Issue 4, Page 577-580, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 13, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica,Volume 107, Issue 4, Page 577-580, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 13, 2018 Category: Pediatrics Source Type: research

Dog bites in a US county: age, body part, and breed in pediatric dog bites
Abstract AimTo compare characteristics of gender, age, body part, and breed in dog bites. MethodsWe reviewed 14,956 dog bites (4,195 pediatric) reported to the Allegehny County Health Department, USA, between 2007‐2015. Using pre‐defined age groups, we performed linear regression to assess for subject age and bite frequency and used binary logistic regression to evaluate for differences in gender and body part and chi‐squared tests with Bonferroni correction to evaluate for differences in reported breeds with age. ResultsThere was a negative correlation (‐0.80, r2=0.64) between age and bite frequency. Children 0‐...
Source: Acta Paediatrica - January 13, 2018 Category: Pediatrics Authors: Sriram Ramgopal, Lauren Bealafeld Brungo, Michael Bykowski, Raymond Pitetti, Robert Hickey Tags: Regular Article Source Type: research

Duration of anaemia during the first week of life is an independent risk factor for retinopathy of prematurity
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 11, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 11, 2018 Category: Pediatrics Source Type: research

Highlights in this issue
(Source: Acta Paediatrica)
Source: Acta Paediatrica - January 11, 2018 Category: Pediatrics Authors: Anna K äll, Hugo Lagercrantz Tags: Highlights in this issue Source Type: research

Issue Information
(Source: Acta Paediatrica)
Source: Acta Paediatrica - January 11, 2018 Category: Pediatrics Tags: Issue Information Source Type: research

Urine dipstick tests can aid decision ‐making when treating infants with unexplained fever, but more research is needed
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 10, 2018 Category: Pediatrics Source Type: research

Playing music to preemies: boosting of soothing the brain?
Acta Paediatrica,Volume 107, Issue 4, Page 549-550, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 10, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 10, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica,Volume 107, Issue 4, Page 549-550, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 10, 2018 Category: Pediatrics Source Type: research

Urine dipstick tests can aid decision ‐making when treating infants with unexplained fever, but more research is needed
(Source: Acta Paediatrica)
Source: Acta Paediatrica - January 10, 2018 Category: Pediatrics Authors: Astha Panghal, Aakash Pandita, Girish Gupta, Kirti Naranje, Anita Singh Tags: Reader's Forum Source Type: research

Playing music to preemies: boosting of soothing the brain?
(Source: Acta Paediatrica)
Source: Acta Paediatrica - January 10, 2018 Category: Pediatrics Authors: Sampsa Vanhatalo Tags: Editorial Source Type: research

Does Erythropoietin monotherapy reduce mortality or moderate/severe disability in neonates with hypoxic ischaemic encephalopathy?
Acta Paediatrica,Volume 107, Issue 4, Page 722-722, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 9, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica,Volume 107, Issue 4, Page 722-722, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 9, 2018 Category: Pediatrics Source Type: research

Does Erythropoietin monotherapy reduce mortality or moderate/severe disability in neonates with hypoxic ischaemic encephalopathy?
(Source: Acta Paediatrica)
Source: Acta Paediatrica - January 9, 2018 Category: Pediatrics Authors: Joseph S. Bircher, Dmitry Dukhovny Tags: EBNEO Commentary Source Type: research

Walter Harris (1647 –1732) and his contribution to paediatrics
Acta Paediatrica,Volume 107, Issue 4, Page 581-581, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 8, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica,Volume 107, Issue 4, Page 581-581, April 2018. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 8, 2018 Category: Pediatrics Source Type: research

Endocrine manifestations in children with Williams –Beuren syndrome
Abstract AimEndocrine abnormalities in Williams–Beuren syndrome (WBS) include growth retardation, precocious puberty, hypercalcaemia and thyroid disorders. We aimed to characterise these abnormalities in a national cohort of children with WBS. MethodsA retrospective study comprising a national cohort of individuals with WBS in Israel (16 males, 18 females) followed between 2010 and 2016. ResultsThe age at diagnosis of WBS was 1.4 ± 1.0 years. Height standard deviation score (SDS) at last visit was correlated with the midparental height SDS (r = 0.46 p = 0.007). Yet, participa...
Source: Acta Paediatrica - January 8, 2018 Category: Pediatrics Authors: Yael Levy ‐Shraga, Doron Gothelf, Shiran Pinchevski‐Kadir, Uriel Katz, Dalit Modan‐Moses Tags: Regular Article Source Type: research

Neurodevelopment of children born very preterm and free of severe disabilities: the Nord ‐Pas de Calais Epipage cohort study
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 5, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 5, 2018 Category: Pediatrics Source Type: research

Exploratory and confirmatory studies have different targets and both are needed in clinical research
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Source Type: research

Comment on how foetal growth restriction and preterm birth affects cardiac morphology and function during infancy
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Source Type: research

Exposure to human voices has beneficial effects on preterm infants in the neonatal intensive care unit
Acta Paediatrica, EarlyView. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Source Type: research

---
Acta Paediatrica, Ahead of Print. (Source: Acta Paediatrica)
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Source Type: research

Comment on how foetal growth restriction and preterm birth affects cardiac morphology and function during infancy
(Source: Acta Paediatrica)
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Authors: PP Bassareo, G Mercuro Tags: Reader ’s Forum Source Type: research

Obese children aged 4 –6 displayed decreased fasting and postprandial ghrelin levels in response to a test meal
This study compared the fasting ghrelin and insulin levels of obese children aged 4–6 with those of normal weight children and tested postprandial ghrelin levels in the obese children after a standard breakfast. MethodsWe recruited 67 children at Lund University Hospital from 2008 to 2011. They comprised 30 obese children from a weight study and 37 normal weight children receiving minor elective surgery. Their mean ages were 4.7 ± 0.6 and 4.3 ± 0.8 years, respectively. The obese children ate a standard breakfast, and postprandial ghrelin was measured after 60 minutes. ResultsThe obese children had lower...
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Authors: Jenny Önnerfält, Charlotte Erlanson‐Albertsson, Caroline Montelius, Kristina Thorngren‐Jerneck Tags: Regular Article Source Type: research

Long ‐term cardiovascular reprogramming by short‐term perinatal exposure to nicotine's main metabolite cotinine
Abstract AimGather ‘proof‐of‐concept’ evidence of the adverse developmental potential of cotinine (a seemingly benign biomarker of recent nicotine/tobacco smoke exposure). MethodsPregnant C57 mice drank nicotine‐ or cotinine‐laced water for 6 wks from conception (NPRE = 2% saccharin + 100 μg nicotine/mL; CPRE = 2% saccharin + 10 μg cotinine/mL) or 3 wks after birth (CPOST = 2% saccharin + 30 μg cotinine/mL). Controls drank 2% saccharin (CTRL). At 17 ± 1 weeks (male pups; CTRL n = 6; CPOST n = 6; CPRE n = 8; NPRE n = 9), we assessed (i) cardiovascular control during sleep; (ii) arterial r...
Source: Acta Paediatrica - January 4, 2018 Category: Pediatrics Authors: Stefano Bastianini, Viviana Lo Martire, Alessandro Silvani, Giovanna Zoccoli, Chiara Berteotti, Hugo Lagercrantz, Anders Arner, Gary Cohen Tags: Regular Article Source Type: research