From CT scanning to 3D printing technology: a new method for the preoperative planning of a transcutaneous bone-conduction hearing device.
Authors: Canzi P, Marconi S, Manfrin M, Magnetto M, Carelli C, Simoncelli AM, Fresa D, Beltrame M, Auricchio F, Benazzo M Abstract SUMMARY: The aim of the present study was to assess the feasibility and utility of 3D printing technology in surgical planning of a transcutaneous bone-conduction hearing device (Bonebridge®) (BB), focusing on the identification of the proper location and placement of the transducer. 3D printed (3DP) models of three human cadaveric temporal bones, previously submitted to CT scan, were created with the representation of a topographic bone thickness map and the sinus pathway on the ou...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Tongue carcinoma in young adults: a review of the literature.
Authors: Paderno A, Morello R, Piazza C Abstract SUMMARY: A recent reduction in the number of smoke-related tumours has been observed thanks to the diffusion of anti-tobacco campaigns carried out in the majority of developed countries. Nevertheless, as demonstrated by recent global epidemiologic studies, squamous cell carcinoma of the mobile tongue appears to be progressively increasing in incidence, particularly among young adults and especially in females. The driving mechanism responsible for such changes is still to be precisely defined. Several genetic studies have compared the mutational pattern of tongue squ...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Electrochemotherapy: a well-accepted palliative treatment by patients with head and neck tumours.
Authors: Pichi B, Pellini R, DE Virgilio A, Spriano G Abstract SUMMARY: Electrochemotherapy (ECT) is a well established treatment strategy for skin tumuors. The aim of this study was to evaluate the feasibility and efficacy of electrochemotherapy in the palliative setting in patients with head and neck malignancies, in terms of improvement of quality of life and in control of pain and bleeding. Twenty-four patients with a loco-regional M0/M1 relapse not suitable for cure with radical intent by surgery or radiotherapy (RT) and not suitable for systemic therapy and/or already treated with it, were admitted to ECT pro...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Clinical utility of an ultrasensitive thyroglobulin assay in the follow-up of patients with differentiated thyroid cancer: can the stimulation test be avoided in patients with an intermediate recurrence risk?
Authors: Flores-Rebollar A, Pérez-Díaz I, Lagunas-Bárcenas S, García-Martínez B, Rivera-Moscoso R, Fagundo-Sierra R Abstract SUMMARY: Serum thyroglobulin (Tg) measurement during suppression with levothyroxine (LT4) using an ultrasensitive assay (OnT4-Tg) has been proposed as a replacement of TSH-stimulated Tg measurement (OffT4-Tg) in management of patients with differentiated thyroid cancer (DTC). The aim of this study is to evaluate the capacity of an ultrasensitive Tg assay in predicting an OffT4-Tg> 2.0 ng/mL based on the OnT4-Tg in patients with DTC and an intermediate rec...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Efficacy of microsurgery in Reinke's oedema evaluated by traditional voice assessment integrated with the Vocal Extent Measure (VEM).
Authors: Salmen T, Ermakova T, Schindler A, Ko SR, Göktas Ö, Gross M, Nawka T, Caffier PP Abstract SUMMARY: There are few data analysing to what specific extent phonomicrosurgery improves vocal function in patients suffering from Reinke's oedema (RE). The recently introduced parameter vocal extent measure (VEM) seems to be suitable to objectively quantify vocal performance. The purpose of this clinical prospective study was to investigate the outcomes of phonomicrosurgery in 60 RE patients (6 male, 54 female; 56 ± 8 years ([mean ± SD]) by analysing its effect on subjective and objective voca...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Efficacy of trans-nasal fiberendoscopic injection laryngoplasty with centrifuged autologous fat in the treatment of glottic insufficiency due to unilateral vocal fold paralysis.
In conclusion, trans-nasal fiberendoscopic IL with centrifuged autologous fat seems to be a safe, feasible and efficacious phonosurgical procedure for treatment of glottic insufficiency due to unilateral vocal fold paralysis. PMID: 29984796 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Moderate OSAS and turbinate decongestion: surgical efficacy in improving the quality of life and compliance of CPAP using Epworth score and SNOT-20 score.
The objective of our work is to assess the role of nasal surgery on symptoms of moderate OSA. Recent studies have confirmed that isolated nasal surgery improves quality of life (QOL), but not the apnoea hypopnoea index (AHI) during polygraph registration. We enrolled 30 patients, aged between 29 and 64 years (mean 50.53 ± 9.20), 26 males and 4 females, with a mean BMI of 26.07 ± 2.81 kg/m2, who were affected by moderate OSAS. All patients underwent otolaryngologycal pre-operative evaluation, home respiratory polygraph and subjective evaluation through Sino-Nasal-Outcome Test (SNOT-20) and Epworth Sleepiness S...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Implementing strategies for data collection in chronic rhinosinusitis.
Authors: Castelnuovo P, Bandi F, Preti A, Sica E, DE Bernardi F, Gallo S Abstract SUMMARY: Chronic rhinosinusitis (CRS) is a debated topic in the international rhinologic literature because of its high prevalence, heterogeneity of clinical manifestations and unpredictability of disease course. Recently, the focus in CRS research has moved to identify biological subtypes that might explain its aetiology and clinical variability. However, these analyses are still expensive and limited to scientific purposes, so that they cannot be used on a large scale in daily practice. For this reason, we wondered if it was possibl...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Bromelain's penetration into the blood and sinonasal mucosa in patients with chronic rhinosinusitis.
Authors: Passali D, Passali GC, Bellussi LM, Sarafoleanu C, Loglisci M, Manea C, Iosif C, Passali FM Abstract SUMMARY: The aim of this research is to investigate penetration of Bromelain into sinonasal mucosa in patients with chronic rhinosinusitis (CRS) versus a control group. Bromelain is derived from pineapple (Ananas comosus) and has various pharmacological effects. 40 patients (20 patients and 20 controls) were enrolled in the study. Bromelain 500 mg tablet twice daily was administered for 30 days. We scored bromelain presence in turbinate and ethmoid mucosas and in the serum of both the groups. Bromelain has ...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Effect of loading of the central part of the tympanic membrane on pure tone audiometry.
In conclusion, loading of the tympanic membrane by different masses affects the air conduction hearing threshold by only 340 mg (25 λ), which is very large in comparison to the mass of ossicles, without any significant effects on bone conduction hearing. PMID: 29984800 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Transtympanic Hearing Aid: exploratory study on a new device.
In conclusion, these outcomes provide the first evidence of the potential benefits of the THA over standard open-fit HAs. Nevertheless, these preliminary outcomes require further confirmation. PMID: 29984801 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Genes important for otoneurological diagnostic purposes - current status and future prospects.
Authors: Pawlak-Osiñska K, Linkowska K, Grzybowski T Abstract SUMMARY: This review focuses on the current knowledge of the genes responsible for non-syndromic hearing loss that can be useful for otoneurological diagnostic purposes. From among a large number of genes that have been associated with non-syndromic hearing impairment, we selected several best-known genes, including the COCH gene, GJB2, GJB6 and SLC26A4, and we describe their role and effects of mutations and prevalence of mutations in various populations. Next, we focus on genes associated with tinnitus. Important areas for further research inclu...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Bone-anchored hearing implant surgery: our experience with linear incision and punch techniques.
This study confirms the low rate of intra and postoperative complications during BAHI surgery and documents the simplicity of execution of the novel MIPS technique, with a significant reduction in surgical time compared to the other two techniques, and positive effects in terms of health care costs. PMID: 29984803 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

The short- and long-term adverse effects of FGF-2 on tympanic membrane perforations.
This study suggests that the topical application of fibroblast growth factor-2 to human traumatic tympanic membranes is safe. Otorrhoea was the most common short-term side-effect; other less common side-effects included otitis media with effusion and reperforation. No serious long-term side-effects were found. PMID: 29984804 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Is the team leading surgeon criminally liable for his collaborators' errors? Judges confirm responsibility and condemn an otorhinolaryngologist.
Authors: Montanari Vergallo G, Ralli M, DI Luca A, DI Luca NM Abstract SUMMARY: In current healthcare, delivery of medical and surgical treatment takes place in a multidisciplinary manner. This raises the problem of distinguishing the conditions under which the person who has properly carried out his duties, respecting the related leges artis, can be held responsible for damages materially caused by another member of the medical team. Jurisprudence has developed the so-called "principle of trust" for which every member of the team can rely on the fact that other members are acting in compliance with the l...
Source: Acta Otorhinolaryngologica Italica - July 10, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Emerging and re-emerging infectious disease in otorhinolaryngology.
Authors: Scasso F, Ferrari G, DE Vincentiis GC, Arosio A, Bottero S, Carretti M, Ciardo A, Cocuzza S, Colombo A, Conti B, Cordone A, DE Ciccio M, Delehaye E, Della Vecchia L, DE Macina I, Dentone C, DI Mauro P, Dorati R, Fazio R, Ferrari A, Ferrea G, Giannantonio S, Genta I, Giuliani M, Lucidi D, Maiolino L, Marini G, Marsella P, Meucci D, Modena T, Montemurri B, Odone A, Palma S, Panatta ML, Piemonte M, Pisani P, Pisani S, Prioglio L, Scorpecci A, Scotto DI Santillo L, Serra A, Signorelli C, Sitzia E, Tropiano ML, Trozzi M, Tucci FM, Vezzosi L, Viaggi B Abstract SUMMARY: Emerging and re-emerging infectious disease...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

The role of laryngectomy in locally advanced thyroid carcinoma. Review of 16 cases.
Authors: Chala AI, Vélez S, Sanabria A Abstract SUMMARY: Locally advanced disease with larynx invasion is a challenge to the surgeon, but laryngectomy is almost never necessary in thyroid carcinoma. The aim of this study was to review the clinical outcomes of patients with locally advanced thyroid carcinoma invading the larynx who underwent laryngectomy. A case series of patients treated in a tertiary care hospital was reviewed. Data about the type of operation, method of reconstruction, complications and overall survival of 16 patients operated on between 2002 and 2015 with larynx invasion is presented. The...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Cyclamen europaeum improves the effect of oral antibiotics on exacerbations and recurrences of chronic rhinosinusitis: a real-life observational study (CHRONOS).
Authors: Lopatin AS, Ivanchenko OA, Soshnikov SS, Mullol J Abstract SUMMARY: Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and paranasal sinuses affecting 11% of the European population. Cyclamen europaeum plant extract (CE) has demonstrated efficacy in treating acute rhinosinusitis, but its role in CRS exacerbations remains unknown. In this real-life, prospective, epidemiological, observational study, a total of 317 patients with exacerbations of CRS without nasal polyps (CRSsNP) of moderate severity were treated using three different options: oral antibiotics, CE extract nasal spray, or the ...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Modification of growth, immunologic and feeding parameters in children with OSAS after adenotonsillectomy.
In conclusion, children affected by adenotonsillar hypertrophy and OSAS do not show significant growth delay, but they do experience a slowdown in growth rate. After adeno-tonsillectomy, the speed of growth soon increases, as weight and growth increase notwithstanding an unchanged food intake. Moreover, surgery does not cause reduction in the efficiency of the immune system. PMID: 29967551 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Binocular cyclotorsion in superior vestibular neuritis.
Authors: Lapenna R, Pellegrino A, Ricci G, Cagini C, Faralli M Abstract SUMMARY: Conjugated cyclotorsion of the eyes toward the affected side can commonly be observed in vestibular neuritis. The aim of this study was to assess the differences in cyclotorsion between the ipsi- and contralesional eye during selective involvement of the superior branch of the vestibular nerve. We studied binocular cyclotorsion through ocular fundus photographs in 10 patients affected by acute superior vestibular neuritis (SVN). Cyclotorsion was also studied in 20 normal subjects. All SVN patients showed an ipsilesional cycloversion of...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Transtracheal endoscopic-assisted resection of a rare inflammatory myofibroblastic tumour in adult trachea: a case report.
We describe an 18-year-old woman who presented with respiratory difficulty to the emergency department. On clinical examination, the patient had complete absence of breath sounds on the right side of the chest. CT of the chest and virtual bronchoscopy revealed a polypoidal soft tissue mass lesion involving the carina with occlusion of right main bronchus. Endoscopic-assisted resection was performed under general anaesthesia and the final pathological diagnosis was tracheal IMT. PMID: 29967553 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

The efficacy of telerehabilitation in dysphagic patients: a systematic review.
Authors: Nordio S, Innocenti T, Agostini M, Meneghello F, Battel I Abstract SUMMARY: Telerehabilitation is the use of telecommunications technology for rehabilitation. Recently, some studies have shown positive effects of telerehabilitation of swallowing disorders, yet there are no systematic reviews verifying the evidence. The aim of this review is to assess the effects of telerehabilitation in the field of dysphagia as an alternative to face-to-face patient care, considering swallowing recovery and/or quality of life in different patient populations. We searched the Cochrane Library, MEDLINE, EMBASE, Google Schol...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Elective neck dissection during salvage surgery after radiotherapy in patients with head and neck squamous cell carcinoma.
Authors: Pedemonte G, Esteller E, Villatoro JC, Costa JM, Valero C, Quer M, León X Abstract SUMMARY: Elective neck dissection in patients with recurrent head and neck squamous cell carcinoma (HNSCC) without evidence of neck disease (crN0) is poorly defined. A retrospective review was carried out on 165 crN0 patients treated with salvage surgery and elective neck dissection. Multivariate Cox analysis and recursive partitioning analysis were used to evaluate prognostic factors. The frequency of occult neck node metastases in the neck dissection (rpN+) was 16.4%. The risk of occult metastases for glottic rpT1-T...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

IFN- γ and other serum cytokines in head and neck squamous cell carcinomas.
IFN-γ and other serum cytokines in head and neck squamous cell carcinomas. Acta Otorhinolaryngol Ital. 2018 Apr;38(2):94-102 Authors: Bussu F, Graziani C, Gallus R, Cittadini A, Galli J, DE Corso E, DI Cintio G, Corbi M, Almadori G, Boninsegna A, Paludetti G, Sgambato A Abstract SUMMARY: Altered immune responses have been reported in head and neck cancer, and some of these responses have been associated with poor clinical outcomes. A multiple-array technology platform was used to simultaneously evaluate the levels of 25 cytokines. Pre-treatment serum levels were evaluated in 31 HNSCC patients and...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Long-term outcomes of alternating chemoradiotherapy in patients with advanced nasopharyngeal cancer: a single-centre experience over the last decade.
Authors: Saijoh S, Matsuzuka T, Sato H, Suzuki M, Ikeda M, Suzuki R, Nakaegawa Y, Omori K Abstract SUMMARY: We assessed the long-term outcomes of alternating chemoradiotherapy (ACRT) using 5-fluorouracil and cisplatin (FP) in 25 patients with stage II or advanced nasopharyngeal cancer treated at our institution between April 1999 and April 2010. Median follow-up duration was 87 months (range 2-189). According to the 2009 TNM classification (UICC), six patients were in stage II, nine in stage III, and 10 in stage IV. Treatment completion, response and five-year survival rates were retrospectively assessed. ACRT was ...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Objective assessment of subjective tinnitus through contralateral suppression of otoacoustic emissions by white noise: effects of frequency, gender, tinnitus bilaterality and age.
Authors: Riga M, Komis A, Maragoudakis P, Korres G, Ferekidis E, Danielides V Abstract SUMMARY: Accumulating evidence seems to support an association between tinnitus and medial olivocochlear bundle (MOCB) dysfunction. Most studies use patient/control comparisons to support this correlation. The aim of this study was to investigate the hypothesis in a substantially different way and evaluate the roles of gender, age, frequency and tinnitus bilaterality as possible confounding factors. The population consisted of 78 normal hearing patients with chronic tinnitus, 28 normal hearing controls, 19 presbycousic tinnitus p...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Vertigo returning to the sitting position after the Semont manoeuvre. Is it a prognostic symptom?
Authors: Albera A, Boldreghini M, Canale A, Albera R, Gervasio CF Abstract SUMMARY: Benign paroxysmal positional vertigo (BPPV) is a frequent benign vestibular condition usually managed with particle repositioning manoeuvres, such as Semont manoeuvre (SM). Since few authors have described prognostic aspects of liberatory manoeuvres, the purpose of the present study was to investigate the possibility of considering vertigo in the final sitting position of the SM as a prognostic symptom in the outcome of posterior BPPV. One hundred and thirteen patients with diagnosis of unilateral posterior BPPV were taking into acc...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Acquisition of surgical skills for endoscopic ear and lateral skull base surgery: a staged training programme.
Authors: Alicandri-Ciufelli M, Marchioni D, Pavesi G, Canzano F, Feletti A, Presutti L Abstract SUMMARY: Endoscopic ear surgery is radically changing the treatment of several middle and inner ear pathology, but its learning presents well-known manual and technical difficulties. The aim of this paper is be to present a training programme based on a modular model of increased difficulties. The experience from 2007 to 2016 at the University Hospital of Modena and University Hospital of Verona was reviewed and analysed for further considerations and to establish stages of training. The increasing experience of expert s...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Retrospective epidemiological study of mandibular rotational types in patients with orthodontical malocclusion.
Authors: Saccomanno S, Deli R, DI Cintio G, DE Corso E, Paludetti G, Grippaudo C Abstract SUMMARY: The primary aim of this study was to illustrate the prevalence of facial skeletal discrepancy in an Italian sample. Another aim was to evaluate the effectiveness of the sagittal skeletal discrepancy classification in order to establish a morphologic pattern of growth useful for diagnosis and prediction of therapeutic results. The authors considered a sample of 732 patients (426 females and 306 males) aged between 6 and 17 years old. Cephalometric parameters were evaluated in order to establish a relationship between s...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Eagle's Syndrome, from clinical presentation to diagnosis and surgical treatment: a case report.
In this report, we describe the case of a 60-year-old woman who presented with a severe unilateral trigeminal and glossopharyngeal neuralgia. The patient was subjected to conservative therapy for four months and did not report improvement of the symptoms. After several consultations with different physicians, a diagnosis was accomplished by radiological investigation (multidetector computer tomography with multi-planar reconstructions and 3D volumetric reconstructions). Surgical styloidectomy was performed, with subsequent sudden remission of symptoms. Eagle's syndrome represents a commonly unrecognised nosological entity,...
Source: Acta Otorhinolaryngologica Italica - July 5, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Anterior palatoplasty in the treatment of obstructive sleep apnoea - a systemic review.
This study seeks to determine the objective and subjective success rates of anterior palatoplasty and its variants for the treatment of obstructive sleep apnoea (OSA). A systematic review with two independent searches of Medline, PubMed, Cochrane Library and Evidence Based Medicine Reviews was performed to identify publications relevant to OSA and anterior palatoplasty. All relevant studies published before 30 June 2015 were included. Six studies were included in the systematic review. The numbers of patients in each paper ranged from 13 to 77 (total = 240), and mean age ranged from 21 to 51 years. Substantial and consiste...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Nerve and vein preserving neck dissections for oral cancers: a prospective evaluation of spinal accessory nerve function and internal jugular vein patency following treatment.
In conclusion, even though nerve dysfunction compromised shoulder abduction, vein dysfunction rarely resulted in any significant clinical impact. PMID: 29756608 [PubMed - in process] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Impact of resection margin status on oncological outcomes after CO2 laser cordectomy.
This study aims to assess the impact of margin status after transoral laser surgery on local control, survival and organ preservation rates; the decision-making process and treatment options in cases with positive margins are also discussed. We retrospectively reviewed the clinical and histological records of 308 consecutive patients with primary early glottic carcinoma (T1a, T1b, selected T2) and treated with endoscopic laser cordectomy. Recurrence rates and survival related to margin status were analysed using the Kaplan-Meier method. Local relapses and disease-free-survival rates were significantly related to excision margin status (p
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

The hump columellar strut: a reliable technique for correction of nasal tip underprojection.
Authors: Giacomini PG, Mocella S, DI Girolamo S, DE Berardinis R, Boccieri A Abstract SUMMARY: Nasal tip under projection is often found in rhinoplasty cases both for congenital or post-traumatic deformity. Nasal trauma may result in alteration of the external and internal nasal structures with following aesthetic impairment and difficulties in breathing. Post-traumatic surgery is frequent, but restoration of pre-traumatic form and function remains a challenge. The present paper describes a new method to increase tip projection by a columellar strut harvested from the autologous nasal bone and cartilage of the rese...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Cochlear obliteration following a translabyrinthine approach and its implications in cochlear implantation.
Authors: Delgado-Vargas B, Medina M, Polo R, Lloris A, Vaca M, Pérez C, Cordero A, Cobeta I Abstract SUMMARY: The most frequent sequelae following a translabyrinthine approach for vestibular schwannoma resection is complete hearing loss on the affected side. Such patients could benefit from a cochlear implant, provided that two essential requisites are met before surgery: a preserved cochlear nerve and a patent cochlea to accommodate the electrode array. The goal of our study is to determine the prevalence and extent of cochlear ossification following a translabyrinthine approach. Postoperative MRI of 41 p...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Cancer of the head and neck: a set of indicators based on register and administrative data.
Authors: Andreano A, Ansarin M, Alterio D, Bruschini R, Valsecchi MG, Russo AG Abstract SUMMARY: Head and neck (H&N) tumours are a heterogeneous group of neoplasms with 5-year relative survival ranging from about 25% for the hypopharynx to 60% for the larynx in Europe. To improve survival rates, along with therapeutic improvements, it is important to standardise and optimise care received by patients with H&N tumours across different healthcare providers. To reach this goal, it is necessary to evaluate adherence to standards of received care at a population level. Published guidelines can serve as the basis...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Neutrophil-to-lymphocyte ratio as a prognostic factor for pharyngocutaneous fistula after total laryngectomy.
Authors: Aires FT, Dedivitis RA, Kulcsar MAV, Ramos DM, Cernea CR Abstract SUMMARY: The role of systemic inflammatory response as a prognostic factor has been proposed in a variety of cancers. The purpose of this study was to investigate the prognostic value of the pretreatment neutrophil-to-lymphocyte ratio (NLR) in the incidence of pharyngocutaneous fistula (PCF) in patients who underwent total laryngectomy. We conducted a retrospective cohort analysis of 141 patients with squamous cell carcinoma of larynx who underwent total laryngectomy from 2009 to 2015. The incidence of PCF was 49.6%. A higher risk of 23% was...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Transoral glossoepiglottopexy in the treatment of adult obstructive sleep apnoea: a surgical approach.
Authors: Roustan V, Barbieri M, Incandela F, Missale F, Camera H, Braido F, Mora R, Peretti G Abstract SUMMARY: The treatment of obstructive sleep apnoea syndrome (OSAS) is still a matter of debate; among the different therapeutic alternatives, both surgical and conservative, treatment with continuous positive airway pressure (CPAP) is considered the "gold standard". The recent scientific literature reports that even if CPAP represents an effective solution for sleep apnoeas, 12% of patients do not benefit from its use. In most cases, primary collapse of the epiglottis is responsible for failure. We devel...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Correlation between musical aptitude and learning foreign languages: an epidemiological study in secondary school Italian students.
Authors: Picciotti PM, Bussu F, Calò L, Gallus R, Scarano E, DI Cintio G, Cassarà F, D'Alatri L Abstract SUMMARY: The aim of this study was to assess if a correlation exists between language learning skills and musical aptitude through the analysis of scholarly outcomes concerning the study of foreign languages and music. We enrolled 502 students from a secondary Italian school (10-14 years old), attending both traditional courses (2 hours/week of music classes scheduled) and special courses (six hours). For statistical analysis, we considered grades in English, French and Music. Our results showed a ...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Treatment of cholesteatoma with intact ossicular chain: anatomic and functional results.
Authors: Pontillo V, Barbara F, DE Robertis V, Quaranta N Abstract SUMMARY: In case of cholesteatoma with intact ossicular chain, the primary aims of surgery are complete removal of the cholesteatoma matrix and reconstruction of a dry and safe middle ear; if possible, ossicular chain continuity and therefore the preoperative hearing must be preserved. The aim of this retrospective study is to present the experience of the U.O.C. Otorinolaringoiatria Universitaria of University of Bari "Aldo Moro" in treatment of intact ossicular chain cholesteatoma with Bondy modified radical mastoidectomy (BMRM) and cana...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Is it possible to define the ideal lips?
Authors: Kar M, Muluk NB, Bafaqeeh SA, Cingi C Abstract SUMMARY: The lips are an essential component of the symmetry and aesthetics of the face. Cosmetic surgery to modify the lips has recently gained in popularity, but the results are in some cases disasterous. In this review, we describe the features of the ideal lips for an individual's face. The features of the ideal lips with respect to facial anatomy, important anatomical landmarks of the face, the facial proportions of the lips and ethnic and sexual differences are described. The projection and relative sizes of the upper and lower lips are as significant to...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Intraparotid facial nerve schwannoma: two case reports and a review of the literature.
Authors: Simone M, Vesperini E, Viti C, Camaioni A, Lepanto L, Raso F Abstract SUMMARY: Schwannomas are rare benign tumours that arise from Schwann cells. The most known and studied is the intracranial vestibular schwannoma, even if it is not the most frequent. More often schwannomas arise from peripheral sensitive nerves, and the vagous is most involved among the cranial nerves. Intraparotid schwannomas account for just 10% of all facial involvement, so they are an extremely rare localisation. At present, there are less than 100 cases described in the literature. We performed a retrospective analysis of parotidect...
Source: Acta Otorhinolaryngologica Italica - May 16, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Association between the increase in incidence of papillary thyroid carcinoma in Crete and exposure to radioactive agents.
Authors: Prokopakis EP, Kaprana A, Karatzanis A, Velegrakis GA, Melissas J, Chalkiadakis G Abstract The mean gamma-ray distribution in Crete during the years after the nuclear accident at Chernobyl and its correlation with the Papillary Thyroid Cancer (PTC) distribution was identified. A total of 4285 patients underwent total thyroidectomy in our centre between 1990 and 2012. Data of gamma-ray (nSv/h) distribution were selected from the Greek Statistical Authorisation. A geo-spatial statistical model was used to estimate the expected number of patients with PTC and Kriging interpolation prediction model to estimate...
Source: Acta Otorhinolaryngologica Italica - March 4, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Paroxysmal positional vertigo despite complete vestibular impairment: the role of instrumental assessment.
We report on two cases of Lindsay-Hemenway syndrome despite complete vestibular failure demonstrated by vestibular instrumental assessment. After making some critical considerations on these findings, we underline the importance of not disregarding the diagnosis of paroxysmal positional vertigo in an established complete labyrinthine loss of function. PMID: 29498717 [PubMed - as supplied by publisher] (Source: Acta Otorhinolaryngologica Italica)
Source: Acta Otorhinolaryngologica Italica - March 4, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Suture lateralisation plus arytenoid cartilage release for treating bilateral vocal fold immobility with mechanical fixation.
Authors: Su WF, Lan MC, Liu SC Abstract A suture lateralisation (SL) instead of an endolaryngeal tissue ablation procedure under endoscopy has been utilised to treat bilateral vocal fold immobility (BVFI) since 1980. However, mechanical fixation (MF) of the cricoarytenoid joint (CAJ) has continually challenged the effectiveness of glottic dilatation both in the SL procedure and the tissue ablation procedure. From 2007 to 2015, a total of 38 patients with BVFI underwent 40 exo-endolaryngeal suture lateralisation (exoeSL) procedures and three were diagnosed with MF in our hospital. For these MF, we introduced an exte...
Source: Acta Otorhinolaryngologica Italica - February 3, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly.
Authors: Molteni G, Valerini S, Alicandri-Ciufelli M, Sprio Phd AE, Crosetti E, Berta GN, Presutti L, Succo G Abstract Oral squamous cell carcinoma (OSCC) diagnoses in elderly patients are expected to double in the next 20 years. Current guidelines suggest surgery as a preferred approach, but elderly patients are hardly considered suitable to challenging surgical treatments. Using a multicentric retrospective analysis, we evaluated the outcomes of 99 patients affected by OSCC and aged at least 70, who underwent to either transoral procedures (TP), open neck resection without (OR) or with reconstruction (ORR). In ou...
Source: Acta Otorhinolaryngologica Italica - February 3, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Transoral robotic surgery in Eagle's syndrome: our experience on four patients.
Authors: Kim DH, Lee YH, Cha D, Kim SH Abstract Eagle's syndrome is characterised by focal pain in the tonsillar fossa on wide mouth opening or head rotation and various accompanying symptoms. While the syndrome is difficult to diagnose, shortening the styloid process via a transoral or transcervical surgical approach has been shown to be the most effective treatment. The aim of this article was to document our experience with a transoral robotic approach to treat Eagle's syndrome and to present the outcomes of four patients. We reviewed the cases of four patients with Eagle's syndrome who underwent transoral robot...
Source: Acta Otorhinolaryngologica Italica - January 13, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

A miRNA signature suggestive of nodal metastases from laryngeal carcinoma.
Authors: Ricciardiello F, Capasso R, Kawasaki H, Abate T, Oliva F, Lombardi A, Misso G, Ingrosso D, Leone CA, Iengo M, Caraglia M Abstract The discovery that miRNAs are frequently deregulated in tumours offers the opportunity to identify them as prognostic and diagnostic markers. The aim of this multicentric study is to identify a miRNA expression profile specific for laryngeal cancer. The secondary endpoint was to identify specific deregulated miRNAs with potential as prognostic biomarkers for tumour spread and nodal involvement, and specifically to search for a miRNA pattern pathognomonic for N+ laryngeal cancer ...
Source: Acta Otorhinolaryngologica Italica - January 13, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Orthopaedic treatment effects of functional therapy on the sagittal pharyngeal dimensions in subjects with sleep-disordered breathing and Class II malocclusion.
Authors: Pavoni C, Cretella Lombardo E, Lione R, Bollero P, Ottaviani F, Cozza P Abstract The purpose of this cephalometric study was to evaluate the craniofacial changes induced by functional treatment of mandibular advancement with special regard to pharyngeal sagittal airway dimensions, tongue and hyoid bone position in subjects with sleep-disordered breathing (SDB) and dentoskeletal Class II malocclusions compared with an untreated Class II control group. 51 subjects (24 female, 27 male; mean age 9.9 ± 1.3 years) with Class II malocclusion and SDB consecutively treated with a functional appliance (Modify...
Source: Acta Otorhinolaryngologica Italica - January 13, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research

Clinical study of extrapulmonary head and neck tuberculosis in an urban setting.
Authors: Monga S, Malik JN, Jan S, Bahadur S, Jetley S, Kaur H Abstract Tuberculosis (TB) of the head and neck region is quite common in endemic countries, but is still misdiagnosed due to its varied presentation and different sites of involvement. The aims of the present study were to present the diversities of presentation of head and neck tuberculosis with the diagnostic predicaments faced during evaluation and to assess treatment response to anti-tubercular treatment (ATT). We analysed 48 patients with head and neck tuberculosis who presented to the Department of Otorhinolaryngology in our tertiary care urban h...
Source: Acta Otorhinolaryngologica Italica - January 13, 2018 Category: ENT & OMF Tags: Acta Otorhinolaryngol Ital Source Type: research