Long Non-coding RNA RP11-252C15.1 is a Potential Biomarker of Prognosis and Hallmark for Leukemogenesis in Children with B-cell Precursor Acute Lymphoblastic Leukemia
CONCLUSION: LncRNA RP11-252C15.1 is a potential oncogene in BCP-ALL pathogenesis and a prognostic biomarker in children with BCP-ALL.PMID:38527424 | DOI:10.1159/000535461 (Source: Acta Haematologica)
Source: Acta Haematologica - March 25, 2024 Category: Hematology Authors: Lili Pan Yongzhi Zheng Hao Zheng Source Type: research
The ratio of serum urea nitrogen to albumin is a better predictor of OS in MM patients than urea nitrogen alone
Conclusion This retrospective study based on the MMRF database showed that high sUN and sUAR levels were positively associated with β2-MG, LDH, and ISS staging, and sUAR exhibited a stronger correlation with OS than sUN alone.PMID:38527425 | DOI:10.1159/000538479 (Source: Acta Haematologica)
Source: Acta Haematologica - March 25, 2024 Category: Hematology Authors: Jiaqi Shao Enfan Zhang Haoguang Chen Zhen Cai Mengmeng Dong Source Type: research
Utility of echocardiogram in neutropenic patients with gram positive bacteremia - a retrospective study
Conclusion In our experience, the yield of echocardiogram in hemato-oncological neutropenic patients with bacteremia is extremely low, owing to reduced probability of IE in this population, and thus could be avoided in most cases.PMID:38527433 | DOI:10.1159/000538449 (Source: Acta Haematologica)
Source: Acta Haematologica - March 25, 2024 Category: Hematology Authors: Neta Sternbach Haim Ben-Zvi Ofir Wolach Moshe Yeshurun Pia Raanani Dafna Yahav Liat Shargian Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
The IRE1 α-endonuclease plays a dual role in regulating the XBP1/miRNA-34a axis and PD-1 expression within Natural Killer cells in Hodgkin Lymphoma
CONCLUSION: The IRE1α-endonuclease emerges as a key player, simultaneously regulating the XBP1s/microRNA-34a-5p/PD-1 axis in NK-cells, a process disrupted in HL. Targeting the IRE1α-pathway holds promise as a therapeutic strategy to optimise NK-cell functions in Hodgkin Lymphoma treatments.PMID:38479365 | DOI:10.1159/000536044 (Source: Acta Haematologica)
Source: Acta Haematologica - March 13, 2024 Category: Hematology Authors: Karolina Bednarska Gayathri Thillaiyampalam Sally Mujaj Jamie Nourse Jay Gunawardana Muhammed B Sabdia Soi C Law Anna Pilaar Qingyan Cui Lilia M de Long Frank Vari Maher K Gandhi Alexandre S Cristino Source Type: research
Efficacy of preexposure prophylaxis with monoclonal-antibody tixagevimab-cilgavimab against emerging SARS-CoV-2 resistant variants in patients with chronic lymphocytic leukemia
Conclusion Efficacy of preexposure prophylaxis with TGM/CGM in patients with CLL is significantly reduced in era of Omicron and its sublineages BA2, BA4 and BA5.PMID:38471491 | DOI:10.1159/000537690 (Source: Acta Haematologica)
Source: Acta Haematologica - March 12, 2024 Category: Hematology Authors: Ohad Benjamini Tamar Tadmor Abraham Avigdor Rotem Gershon Limor Kliker Florin Fares Nofar Atari Ilana Laevsky Bayan Abd Elkader Tammy Hod Orit Golan-Shany Michal Mandelboim Galia Rahav Source Type: research
Efficacy of preexposure prophylaxis with monoclonal-antibody tixagevimab-cilgavimab against emerging SARS-CoV-2 resistant variants in patients with chronic lymphocytic leukemia
Conclusion Efficacy of preexposure prophylaxis with TGM/CGM in patients with CLL is significantly reduced in era of Omicron and its sublineages BA2, BA4 and BA5.PMID:38471491 | DOI:10.1159/000537690 (Source: Acta Haematologica)
Source: Acta Haematologica - March 12, 2024 Category: Hematology Authors: Ohad Benjamini Tamar Tadmor Abraham Avigdor Rotem Gershon Limor Kliker Florin Fares Nofar Atari Ilana Laevsky Bayan Abd Elkader Tammy Hod Orit Golan-Shany Michal Mandelboim Galia Rahav Source Type: research
Momelotinib bei Myelofibrose und An ämie
Acta Haematol. 2024 Mar 11;147(2):254-256. doi: 10.1159/000538289. Online ahead of print.NO ABSTRACTPMID:38467116 | DOI:10.1159/000538289 (Source: Acta Haematologica)
Source: Acta Haematologica - March 11, 2024 Category: Hematology Source Type: research
