Lymphomatoid papulosis type B in a patient with Crohn's disease treated with TNF-alpha inhibitors infliximab and adalimumab
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Rowell syndrome in Nigeria: systemic lupus erythematosus presenting as recurrent erythema multiforme in a young woman
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Tridimensional matryoshka tatoo: An important adverse reaction
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Oral and vulvar lichen sclerosus
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Grover's disease in a kidney transplant recipient
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Furuncular myiasis of the lower leg
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Occupational airborne dermatitis caused by omeprazole
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Baclofen-induced dyshidrosiform bullous pemphigoid in a paraplegic patient complicated with methicillin-resistant Staphylococcus aureus (mrsa) and urinary infection
Bullous pemphigoid (BP) is an autoimmune disorder which is usually chronic, with blistering that predominantly affects the skin and occasionally the mucosa, and which includes several different types. One of them is a very rare dyshidrosiform type which is localized on the hands and feet with small or large blisters on the palmoplantar surfaces. BP resulting from a drug reaction is a relatively rare occurrence, and so far more than 50 different medications have been identified as triggers. The aim of this article was to present the case of a paraplegic patient who developed this rare dyshidrosiform type of BP while he was ...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Eruptive nevi on the palms and soles with no association with an underlying disease or medications
Eruptive melanocytic nevi are an unusual phenomenon characterized by sudden onset of multiple melanocytic nevi on previously unaffected skin. The majority of case reports have linked this condition with blistering skin disease or immunosuppression. There are only three reports of eruptive nevi developing on the palms and /or soles in healthy individuals. Herein we present the clinical and dermoscopic features of two cases of   eruptive acral nevi that developed in healthy individuals in the absence of any recognizable underlying disease and review the current literature of eruptive nevi.  (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

The role of skin barrier in periorificial dermatitis
Periorificial dermatitis, mostly known as perioral dermatitis, is a benign inflammatory facial dermatosis which can be a severe burden and even disfiguring and psychologically disturbing. The disease still presents a challenge for physicians when it comes to etiology and appropriate therapy. Although a variety of extrinsic and intrinsic factors have been proposed as etiopathogenetic factors, none of these fully explain complex pathogenesis of the disease. There is more evidence that supports beliefs that the epidermal barrier dysfunction is an underlying main pathogenic factor that contributes to persistent cutaneous infla...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Melanoma development: Current knowledge on melanoma pathogenesis
The pathogenic features of melanomas include growth and amplification of atypical melanocytes associated with several features (self-sufficiency of growth factors, insensitivity to growth inhibitors, evasion of cellular apoptosis, limitless replicative potential, sustained angiogenesis, tissue invasion, and metastasis). These melanoma pathogenic events can be triggered by activating oncogenes or inactivating tumor-suppressor genes by means of molecular mechanisms such as dotted mutations, deletions, and translocations or epigenetic mechanisms such as microRNA expression and promoter methylation. In melanomas, an analysis o...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

The role of CD8+ T-cells and their cytokines in the pathogenesis of psoriasis
The important role of CD8+ T-cells in the pathogenesis of psoriasis is well-determined. However, besides type 1 cytokines that were formerly known, it was recently found that these cells secrete type 17 and type 22 cytokines. The majority of IL-17A+CD8+ T-cells in the blood belong to a subset of innate T-cells named mucosa-associated invariant T-cells (MAIT). However, the majority of IL-17A+CD8+ T-cells in psoriatic epidermis are conventional T-cells and are up-regulated in psoriasis. In contrast to Th17 cells that secrete only IL-17, Tc17 cells secrete IFN- ϒ, TNF-α, CCL20, IL-22, and granzyme B as well. The k...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Mycosis fungoides: A ten-year Turkish experience
Mycosis fungoides is the most common primary cutaneous T cell lymphoma, characterized by erythematous patches and plaque lesions with slow progression to cutaneous tumors or extracutaneous involvements in some patients. We aimed to evaluate the clinical characteristics, treatment responses, disease courses, and mortality rates of our MF cases. The data of 100 patients with MF were retrospectively examined from medical records in our clinic between January 2005 and January 2015. Demographic and clinical characteristics of the patients, disease stage, treatment protocols, response to treatment, recurrence, progression, and m...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Dermoscopic differentiation of facial lentigo maligna from pigmented actinic keratosis and solar lentigines
The differential diagnosis of lentigo maligna (LM) from pigmented actinic keratosis (PAK) and solar lentigines (SL) remains a challenge for clinicians, especially in the early stages of LM when there are no distinctive dermoscopic features. Objective of this study was to evaluate the frequencies of selective dermoscopic criteria in LM, PAK, and SL and to find the specific combination of distinguishing dermoscopic criteria for LM. Dermoscopists blinded to histopathological diagnosis evaluated 42 LM, 107 PAK, and 16 SL for the presence of predefined dermoscopic criteria. The differences in the presence of dermoscopic criteri...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Application of indirect immunofluorescence on the diagnosis of pemphigus
Pemphigus is an autoimmune bullous disease, and although several diagnostic methods are now in use indirect immunofluorescence (IIF) is still considered an important tool for diagnosing pemphigus because of its convenience, repeatability, and reduced pain for patients. The goal of the present study was to evaluate the diagnostic value of IIF on normal human skin (NS), monkey esophagus (ME), and salt-split skin (SS) for better diagnosis of pemphigus. Clinical data of 70 patients with pemphigus and 56 control were collected. IIF on NS, ME, and SS were assessed separately by observing fluorescein deposition and comparing its ...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Identification and antifungal activity profile of Candida species isolated from patients with pemphigus vulgaris with oral lesions
Pemphigus vulgaris is an autoimmune disease that mostly affects the mucosa and oral cavity.Candida species can invade the mucosal lesions of these patients and cause diseases. The aim of this study was to identify the fungal agents isolated from mucosal lesions and evaluate antifungal activity profile against the isolates. A total of 25 patients with pemphigus vulgaris with active oral lesions and 25 healthy people serving as a control group were included in this study. Identification of the fungal isolates was performed based on conventional methods and DNA sequence analysis of the internal transcribed spacer (ITS) rDNA g...
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Adc 27(3)
(Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - September 20, 2019 Category: Dermatology Source Type: research

Adc 27(2)
(Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 23, 2019 Category: Dermatology Source Type: research

Hyperpigmented mycosis fungoides – a rare entity
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Dermoscopic features of a digital myxoid cyst
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Giant lumbar polypoid tumor with bullae on its surface
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Rowell's syndrome triggered by omeprazole
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Adalimumab – safe and effective therapy for adolescent patient with severe psoriasis and immune thrombocytopenia.
We report the case of an adolescent with severe psoriasis and concomitant immune thrombocytopenia who obtained remission during treatment with adalimumab. Increased concentration of tumor necrosis factor- α seems to be a pathogenic linkage and therapeutic target for both diseases.  (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Cutaneous pseudlolymphoma: A case report
Pseudolymphoma is a benign, reversible, inflammatory, reactive, and polyclonal lymphocyte proliferation, which regresses spontaneously or heals after elimination of the causal factor. A female patient, aged 33, presented with a painful, erythematosus, radiant tumor formation on the skin in the temporal region. The patient had enlarged lymph nodes on the right side of the neck before the appearance of that tumor formation. The dermatoscopic finding was nonspecific. After the tumor biopsy was performed, the diagnosis of reactive lymphatic proliferation – pseudolymphoma or cutaneous lymphoma of B-cell immunophenotype &n...
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

The dermoscopic rainbow pattern - a review of the literature
The “rainbow” pattern is a relatively new dermoscopic term that describes a bluish-reddish coloration together with various colors of the rainbow observable mainly through polarized light dermoscopy. Despite several theories, the rainbow pattern has not yet been clearly associated with any particula r histological structure. This feature has been described in skin lesions with abundant vascularization such as Kaposi’s sarcoma, basal cell carcinoma, scars, squamous cell carcinoma, melanoma, and others. In this paper we conducted a review of the available studies regarding the appearance of the rainbow patt...
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Bilateral periorbital ecchymosis following ablative laser removal of xanthelasma palpebrarum
We report the case of a 48-year-old woman who presented with bilateral periocular ecchymosis after laser removal of xanthelasma palpebrarum. Her medical history was unremarkable. Amyloidosis could be excluded by histopathology. We suggest that periocular ecchymosis is a rare adverse event after minor (laser) surgery of the eyelids and discuss the possible pathogenesis and differential diagnoses.   (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Efficacy of omalizumab in patients with chronic spontaneous urticaria and its association with serum IgE levels and eosinophil count
Chronic spontaneous urticaria can be treated with several drugs such as antihistamines, leukotriene antagonists, cyclosporine, doxepin, hydroxychloroquine, colchicine, and corticosteroids. However, treatment-resistant urticaria significantly reduces quality of life. In recent years, omalizumab has been considered to be an effective treatment option in treatment-resistant cases. We aimed to investigate the clinical efficacy of omalizumab in urticaria and its possible association with serum IgE levels, total eosinophil counts, and basophil percentages. Medical records of 11 patients with chronic spontaneous urticaria treated...
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Knowledge, Attitudes and Behaviours Of Mostar University Students on the harmful effects of ultraviolet radiation exposure - A KAB study
This study shows that Mostar University students have a high level of knowledge about UVR and skin cancer, but their behavior is not sufficiently preventive and appropriate to their knowledge. Medical students often use UV protection measures and employ more preventive behavior than that of other faculty students, but it is still at a low level of prevention. Findings concurred with existing evidence that the knowledge of associated risks from UVR was not sufficient to motivate safer sun-related practices.  (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Correlation between family history and the age of onset of childhood acne in relation to sex and type of acne
Acne vulgaris is a common chronic skin disorder of the pilosebaceous unit with a wide range of clinical presentations, which depend on the age of onset of acne, sex, family history of acne, and genetic factors, especially the genes affecting keratinization and desquamation. This retrospective study investigated pediatric acne using the patients ’ past medical history, with patients aged from newborns to 15 years of age. Acne were further stratified by 5 parameters: sex, age, family history, acne type, and localization. Our main aim was to investigate the possible association between selected parameters and the presen...
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

High body mass index is a risk factor for acne severity in adolescents: A preliminary report
Acne vulgaris is one of the most common chronic dermatological diseases among adolescents. Recent data indicated that a specific diet may affect the course and appearance of acne. The aim of the study was to analyze the relationship between body mass index (BMI) and acne prevalence and severity. This cross-sectional study was conducted among 143 consecutively recruited adolescents aged between 12 and 18. All participants were physically examined, including measurement of weight and height and type and severity of acne. Acne lesions were evaluated as not present (0), mild (1), moderate (2), and severe (3). The predominant t...
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Proliferative actinic keratosis: An invasive squamous cell carcinoma or not?
In conclusion, 25% (13/51) of lesions diagnosed as PAK were invasive SCC, which is of clinical and histopathological significance. Our results suggest that the definition of PAK should be histopathologically revised and that total excisional biopsy instead of punch biopsy should be considered, especially for lesions with a proliferative appearance.  (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Health behaviour changes in cutaneous melanoma survivors
Aim of this study was to   investigate changes in health behavior of melanoma survivors with emphasis on safe sun behavior (SSB) and skin self-examination (SSE). We also identified factors with significant impact on SSE improvement. We performed a cross-sectional (epidemiological) survey based on a structured questionnair e. 150 patients from three medical institutions were invited and 144 patients responded. Statistical analysis was performed with SPSS version 23.0, with the level of significance set to 0.05. After being diagnosed with cutaneous melanoma, patients significantly improved preventive health behavio...
Source: Acta Dermatovenerologica Croatica - July 22, 2019 Category: Dermatology Source Type: research

Adc 27(1)
(Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Reconstruction of the thumb defect following subungual melanoma resection using Foucher ’s flap
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Successful treatment with fusidic acid in a patient with folliculitis decalvans
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Circumscribed juvenile pityriasis rubra pilaris (Type 4) koebnerising after hot water burn: Mild disease with maximum Koebner response
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Lichen sclerosus on the sites of striae distensae and a surgical scar in a patient with coexistent morphea
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Combination of 30% salicylic acid peels and mechanical comedo extraction for the treatment of Favre-Racouchot syndrome
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

An unusual cause of papules on the face
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Pityriasis lichenoid-like mycosis fungoides in a 9-year-old boy: A case report
No abstract available (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Localized perforating granuloma annulare
We present the case of a 31-year-old male patient with a localized form of PGA successfully treated with topical steroids. (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Penicillin-induced cutaneous necrotizing eosinophilic vasculitis with cryofibrinogenemia
We present a case of an 18-year-old girl who developed palpable purpura and hemorrhagic bullae over the lower extremities associated with itching, 7 days after the commencement of penicillin therapy. Plasma cryofibrinogen was positive. Histopathology showed an infiltration of eosinophils within and around the vessel walls and a complete absence of nuclear dust and neutrophils. Oral prednisone at 1 mg/kg induced remission in 2 weeks; the prednisone dose was tapered and discontinued after 2.5 months. There was no evidence of recurrence after 37 months of follow-up. Our patient represents a rare case of drug/penicillin-induce...
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Face and scalp basal cell carcinoma treatment: A review of the literature
Basal cell carcinoma (BCC) is the most frequent skin cancer and is characterized by slow growth, even if it can be locally invasive and rarely metastasizes. Many different phenotypic presentations and histopathologic subtypes have been described, and the current guidelines subdivide BCCs into low-risk (nodular and superficial) and high-risk subtypes (micronodular, infiltrating, and morphoeic BCC and those with squamous differentiation). Dermoscopy allows the identification of the features associated with these different subtypes. Compared with the low-risk forms of BCC, more aggressive ones tend to undergo more frequently ...
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Reticular erythematous mucinosis: A rare cutaneous mucinosis
Reticular erythematous mucinosis (REM) is a rare form of primary cutaneous mucinosis, most often involving the midline of the upper chest or back in middle-aged women.REM bears clinical and histopathologic resemblance to lupus erythematosus tumidus (LET), dermatomyositis, scleredema, and lichen myxedematosus. Early recognition and diagnosis of REM is particularly relevant to exclude the abovementioned diseases, as REM is more benign and has fewer systemic consequences. (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

An update on mucosal melanoma: future directions
By definition, mucosal melanomas are malignant primary tumors originating from melanocytes located in the mucosal membranes of the nasal cavity and accessory sinuses, oral cavity, lips and pharynx, and vulvar, vaginal or uterus, anorectal, or basically any other part of the mucosal surface lining. These malignant melanomas usually occur in occult sites, which in combination with the lack of early specific signs contributes to the delay in diagnosis and poor prognosis of the disease. Given the rarity of mucosal melanomas, knowledge about their pathogenesis and risk factors is insufficient and when compared with cutaneous an...
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Detection of IgG autoantibodies against desmocollin –3 in Greek patients with pemphigus
In this study we examined sera from Greek patients with PV and PF for the presence of IgG autoantibodies against Dsc-3. Immunoblotting for the detection of autoantibodies against Dsc-3 was performed in sera from all cases. Dsc-3 autoantibodies were not detected in either group (PV and PF). Our results confirm the hypothesis that the pathogenic role of Dsc-3 in epidermal blistering in PV and PF remains controversial.  (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Comparing the efficacy of mesotherapy to topical minoxidil in the treatment of female pattern hair loss using ultrasound biomicroscopy: A randomized controlled trial
The efficacy of mesotherapy in the treatment of female pattern hair loss (FPHL) has not yet been evaluated. Aim of the study was to compare the initial efficacy and safety of mesotherapy containing nutritional supplements to topical minoxidil 5% solution in FPHL. 30 patients with FPHL were randomly classified into two equal groups: Group A applied minoxidil 5% lotion twice daily; Group B was injected with mesotherapy once weekly. For both groups ultrasound biomicroscopy (UBM) was performed before and at the end of the 12th week of treatment. After treatment, no significant difference was found between both groups with rega...
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

PROFESSOR ZDRAVKO PERI Š, MD, PhD (1927-2018)
On December 4, 2018, death took from us and hisfamily Professor Zdravko Peri š, Croatia’s oldest andmost renowned living dermatovenerologist, after along and severe illness. (Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - April 25, 2019 Category: Dermatology Source Type: research

Adc 26(4)
(Source: Acta Dermatovenerologica Croatica)
Source: Acta Dermatovenerologica Croatica - January 28, 2019 Category: Dermatology Source Type: research