Porokeratosis Ptychotropica on the Penis and Scrotum: A Case Report.
PMID: 30328473 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 17, 2018 Category: Dermatology Authors: Qian YT, Vano-Galvan S, Liu JW, Liu W, Ma DL Tags: Acta Derm Venereol Source Type: research

Skin Lesions Suggesting Type 2 Segmental Mosaicism in Noonan Syndrome.
PMID: 30320868 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 15, 2018 Category: Dermatology Authors: Happle R Tags: Acta Derm Venereol Source Type: research

Aberrant B Cell Subsets and Immunoglobulin Levels in Patients with Moderate-to-severe Psoriasis.
n A PMID: 30320869 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 15, 2018 Category: Dermatology Authors: Kahlert K, Grän F, Muhammad K, Benoit S, Serfling E, Goebeler M, Kerstan A Tags: Acta Derm Venereol Source Type: research

Assessing Punctuate Administration of Beta-alanine as a Potential Human Model of Non-histaminergic Itch.
PMID: 30320870 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 15, 2018 Category: Dermatology Authors: Christensen JD, Lo Vecchio S, Elberling J, Arendt-Nielsen L, Andersen HH Tags: Acta Derm Venereol Source Type: research

Digital Education for Health Professions in the Field of Dermatology: A Systematic Review by Digital Health Education Collaboration.
This study employed a Cochrane review approach to assess the evidence for the effectiveness of health professions' digital education in dermatology to improve knowledge, skills, attitudes and satisfaction. Twelve trials (n = 955 health professionals) met our eligibility criteria. Nine studies evaluated knowledge; of those two reported that digital education improved the outcome. Five studies evaluated skill; of those 3 studies stated that digital education improved this outcome whereas 2 showed no difference when compared with control. Of the 5 studies measuring learners' satisfaction, three studies claimed h...
Source: Acta Dermato-Venereologica - October 15, 2018 Category: Dermatology Authors: Xu X, Posadzki PP, Lee GE, Car J, Smith HE Tags: Acta Derm Venereol Source Type: research

Keratinocyte Transcriptome in Psoriasis: Pathways Related to Immune Responses, Cell Cycle and Keratinization.
oly E Abstract Psoriasis is a common immune-mediated disease resulting from altered cross-talk between keratinocytes and immune cells. Previous transcriptomic studies have identified thousands of deregulated genes in psoriasis skin; however, the transcriptomic changes confined to the epidermal compartment remained poorly characterized. The aim of this study was to characterize the transcriptomic landscape of psoriatic keratinocytes, using sorted CD45neg epidermal cells. Genes with functions in innate immunity, type I interferon response, cell cycle and keratinization were enriched among deregulated genes in psoria...
Source: Acta Dermato-Venereologica - October 15, 2018 Category: Dermatology Authors: Pasquali L, Srivastava A, Meisgen F, Das Mahapatra K, Xia P, Xu Landén N, Pivarcsi A, Sonkoly E Tags: Acta Derm Venereol Source Type: research

Rashes, Erosions and Purulent Fluid in the Intertriginous Areas: A Quiz.
PMID: 30320873 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 15, 2018 Category: Dermatology Authors: Sun Y, Zhang F Tags: Acta Derm Venereol Source Type: research

Measuring Patient Needs and Benefits in Dermatology using the Patient Benefit Index 2.0: A Validation Study.
This study investigated the validity and feasibility of the Patient Benefit Index 2.0 (PBI 2.0), a short instrument to assess patient-relevant treatment benefit. In a cross-sectional study, patients with skin diseases completed the PBI 2.0 alongside instruments on quality of life and disease-specific PBI long versions to assess convergent validity. Feasibility questions appraise comprehensibility, completeness, length, and readability. Data from a longitudinal study were used to explore responsiveness and test-retest reliability. Most patients rated the PBI 2.0 easy to understand, complete, legible, and not too long. The a...
Source: Acta Dermato-Venereologica - October 11, 2018 Category: Dermatology Authors: Topp J, Augustin M, von Usslar K, Gosau R, Reich K, Reusch M, Blome C Tags: Acta Derm Venereol Source Type: research

Pruritus in Chronic Liver Disease: A Questionnaire Survey on 216 Patients.
PMID: 30307026 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 11, 2018 Category: Dermatology Authors: Kido-Nakahara M, Nakahara T, Furusyo N, Shimoda S, Koto K, Kato M, Hayashi J, Koyanagi T, Furue M Tags: Acta Derm Venereol Source Type: research

Influence of Itch and Pain on Sleep Quality in Atopic Dermatitis and Psoriasis.
This study assessed the impact of itch and pain on sleep quality among 100 patients with atopic dermatitis and 100 patients with psoriasis, compared with 50 controls. The Athens Insomnia Scale (AIS) and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate a spectrum of sleep disturbances. Co-existence of insomnia was indicated in the majority of patients; atopic dermatitis (82%), psoriasis (62%). PSQI total scores for patients with atopic dermatitis (8.3 ± 4.2 points) and those with psoriasis (8.1 ± 4.8 points) qualified them, in 80% of cases, as poor sleepers and were signi...
Source: Acta Dermato-Venereologica - October 11, 2018 Category: Dermatology Authors: Kaaz K, Szepietowski JC, Matusiak Ł Tags: Acta Derm Venereol Source Type: research

A Case of Generalized Interstitial Granuloma Annulare and Arthritis Associated with Breast Cancer.
ier M PMID: 30281136 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Clapé A, Vanhaecke C, Durlach A, Bernard P, Jouannaud C, Kpodar L, Cribier B, Viguier M Tags: Acta Derm Venereol Source Type: research

Paraneoplastic Opsoclonus-myoclonus Syndrome Preceding a Mucosal Malignant Melanoma.
PMID: 30281137 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Dresco F, Aubin F, Deveza E, Revenco E, Tavernier L, Puzenat E Tags: Acta Derm Venereol Source Type: research

A Case of Perforating Folliculitis Induced by Vemurafenib.
PMID: 30281138 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Shiraishi K, Masunaga T, Tohyama M, Sayama K Tags: Acta Derm Venereol Source Type: research

Comparison of the Treatment Outcome of Oral Tofacitinib with Other Conventional Therapies in Refractory Alopecia Totalis and Universalis: A Retrospective Study.
In conclusion, oral tofacitinib was more effective than diphenylcyclopropenone immunotherapy and more tolerable than conventional oral treatment after 6 months of treatment. PMID: 30281139 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Shin JW, Huh CH, Kim MW, Lee JS, Kwon O, Cho S, Park HS Tags: Acta Derm Venereol Source Type: research

Induced Vitiligo due to Talimogene Laherparepvec Injection for Metastatic Melanoma Associated with Long-term Complete Response.
PMID: 30281140 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Iglesias P, Ribero S, Barreiro A, Podlipnik S, Carrera C, Malvehy J, Puig S Tags: Acta Derm Venereol Source Type: research

Fractional Ablative CO2 Laser Followed by Topical Application of Sodium Stibogluconate for Treatment of Active Cutaneous Leishmaniasis: A Randomized Controlled Trial.
Abstract Conventional treatment of cutaneous leishmaniasis often leaves permanent scars with frequent psychosocial sequelae. The aim of this study was to compare the efficacy, safety, associated pain and final cosmetic outcome of fractional carbon dioxide (CO2) laser followed by topical application of sodium stibogluconate vs. sodium stibogluconate injections for the treatment of cutaneous leishmaniasis. A total of 181 lesions (20 patients) were randomly assigned to receive intralesional injections of sodium stibogluconate (control group) or fractional CO2 laser treatment followed by topical application of sodium ...
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Artzi O, Sprecher E, Mehrabi JN, Katz O, Hilerowich Y Tags: Acta Derm Venereol Source Type: research

Ultrasound Assessment of Psoriatic Onychopathy: A Cross-sectional Study Comparing Psoriatic Onychopathy with Onychomycosis.
ós J Abstract This cross-sectional study evaluated the usefulness of an ultrasound technique in assessment of nail changes in 35 patients with psoriatic onychopathy and 25 with nail dystrophy secondary to onychomycosis. All patients underwent 3 examinations: a complete clinical assessment; a nail ultrasound study; and fungal culture. Nails of patients with psoriatic onychopathy presented a thinner nail plate and nail bed, measured by ultrasound, than did those with onychomycosis. The percentage of patients with a power Doppler signal ≥2 at nail bed was significantly higher in psoriatic onychopathy than i...
Source: Acta Dermato-Venereologica - October 3, 2018 Category: Dermatology Authors: Moreno M, Lisbona MP, Gallardo F, Deza G, Ferran M, Pontes C, Luelmo J, Maymó J, Gratacós J Tags: Acta Derm Venereol Source Type: research

Characteristics of Pruritus in Relation to Self-assessed Severity of Atopic Dermatitis.
The objective of this study was to explore characteristics of pruritus in atopic dermatitis (AD) in relation to the severity of AD. A web-questionnaire was used, which included the Patient-Oriented SCORing Atopic Dermatitis index, the 5-D itch scale and the Brest questionnaire. A total of 170 participants were included (86.5% women, mean age 30.9 years). Severity [AQ2] was mild for 8.2% of patients, moderate for 38.2% and severe for 53.5%. Mean 5-D itch scale was 13.2. The mean intensity of pruritus was 5.8, and mean sleep loss was 4.7 (from 0 to 10). The participants frequently described burning (61.8%) and stinging (58.8...
Source: Acta Dermato-Venereologica - September 28, 2018 Category: Dermatology Authors: Huet F, Faffa MS, Poizeau F, Merhand S, Misery L, Brenaut E Tags: Acta Derm Venereol Source Type: research

Rapidly Growing Tumour on the Forearm of an 83-year-old Woman: A Quiz.
PMID: 30264162 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 28, 2018 Category: Dermatology Authors: El Habnouni C, Cornillier H, Tauveron V, Guyetant S, Maruani A Tags: Acta Derm Venereol Source Type: research

Unmet Needs in Pemphigoid Diseases: An International Survey Amongst Patients, Clinicians and Researchers.
an MF PMID: 30265372 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 28, 2018 Category: Dermatology Authors: Lamberts A, Yale M, Grando SA, Horváth B, Zillikens D, Jonkman MF Tags: Acta Derm Venereol Source Type: research

Sch öpf-Schulz-Passarge Syndrome: Previously Unreported WNT10A Genotype and Phenotypes in 9 Family Members.
Schöpf-Schulz-Passarge Syndrome: Previously Unreported WNT10A Genotype and Phenotypes in 9 Family Members. Acta Derm Venereol. 2018 Sep 28;: Authors: Zimmermann CE, Soufi M, Ruppert V, Schaefer JR, von Domarus H PMID: 30265373 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 28, 2018 Category: Dermatology Authors: Zimmermann CE, Soufi M, Ruppert V, Schaefer JR, von Domarus H Tags: Acta Derm Venereol Source Type: research

The Importance of Achieving Clear or Almost Clear Skin for Patients: Results from the Nordic Countries of the Global Clear about Psoriasis Patient Survey.
This report highlights stigmatization among Nordic patients with psoriasis and the potential to improve physician-patient communication. PMID: 30250961 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 24, 2018 Category: Dermatology Authors: Rasmussen MK, Enger M, Dahlborn AK, Juvik S, Fagerhed L, Dodge R, Enerbäck C Tags: Acta Derm Venereol Source Type: research

Daylight-photodynamic Therapy in Combination with Corticosteroid and Brimonidine Tartrate for Multiple Actinic Keratoses: A Randomized Clinical Trial.
PMID: 30250962 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 24, 2018 Category: Dermatology Authors: Wiegell SR, Johansen UB, Wulf HC Tags: Acta Derm Venereol Source Type: research

Increase in Vitamin D but not Regulatory T Cells following Ultraviolet B Phototherapy of Patients with Atopic Dermatitis.
This study investigated serum 25-hydroxyvitamin D (25(OH)D) concentrations and circulating regulatory T cells in patients with atopic dermatitis receiving narrow-band ultraviolet B (nbUVB) phototherapy. Thirty adult patients with atopic dermatitis were included. Blood samples were collected at baseline and at weeks 2 and 4 of nbUVB phototherapy. Skin biopsies were taken at baseline and at week 4. Serum 25(OH)D concentrations increased significantly following nbUVB phototherapy (estimate of change from baseline to week 2: 32.00 nmol/l, confidence interval (CI) 20.48-43.52, p 
Source: Acta Dermato-Venereologica - September 24, 2018 Category: Dermatology Authors: Simonsen S, Bonefeld CM, Thyssen JP, Geisler C, Skov L Tags: Acta Derm Venereol Source Type: research

Evaluation of Single Nucleotide Variants in Ethiopian Patients with Atopic Dermatitis.
Bradley M PMID: 30251743 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 24, 2018 Category: Dermatology Authors: Asad S, Tapia-Páez I, Montes AM, Wahlgren CF, Wahlgren CF, Bilcha KD, Nordenskjöld M, Bradley M Tags: Acta Derm Venereol Source Type: research

Fast-growing Painful Leg Ulcers in a 26-year-old Woman with Systemic Lupus Erythematosus: A Quiz.
PMID: 30229266 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Hartmann J, Haenssle HH, Enk AH, Toberer F Tags: Acta Derm Venereol Source Type: research

Occurrence, Chronicity and Intensity of Itch in a Clinical Consecutive Sample of Patients with Skin Diseases: a Multi-centre Study in 13 European Countries.
fer J Abstract Itch is an unpleasant symptom, affecting many dermatological patients. Studies investigating the occurrence and intensity of itch in dermatological patients often focus on a single skin disease and omit a control group with healthy skin. The aim of this multi-centre study was to assess the occurrence, chronicity and intensity (visual analogue scale 0-10) of itch in patients with different skin diseases and healthy-skin controls. Out of 3,530 dermatological patients, 54.3% reported itch (mean ± standard deviation itch intensity 5.5 ± 2.5), while out of 1,094 ...
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Schut C, Dalgard FJ, Halvorsen JA, Gieler U, Lien L, Tomas Aragones L, Poot F, Jemec GB, Misery L, Kemény L, Sampogna F, van Middendorp H, Balieva F, Linder D, Szepietowski JC, Lvov A, Marron SE, Altunay IK, Finlay AY, Salek S, Kupfer J Tags: Acta Derm Venereol Source Type: research

Cytophagic Histiocytic Panniculitis Associated with Myelodysplastic Syndrome.
PMID: 30226527 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Kimura R, Sugita K, Goto H, Yamamoto O Tags: Acta Derm Venereol Source Type: research

Diagnostic Indicators of Rosacea and Demodicosis.
Abstract Papulopustular rosacea and demodicosis are characterized by non-specific symptoms, which can make clinical diagnosis difficult. This retrospective study of 844 patients assessed the diagnostic importance of clinical signs and symptoms that are poorly recognized as being associated with these conditions. In addition to well-known signs (vascular signs (present in 80% of patients), papules (39%), pustules (22%) and ocular involvement (21%)), other signs and symptoms (discreet follicular scales (93%), scalp symptoms (pruritus, dandruff or folliculitis; 38%) and pruritus (15%)) may also suggest a diagnosis no...
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Forton FMN, De Maertelaer V Tags: Acta Derm Venereol Source Type: research

Novel Compound Heterozygous Mutations in RAG1 in a Patient with Cutaneous Lymphoproliferative Disease.
PMID: 30226529 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Xu CC, Chen ZM, Xiong JS, Chen H, Sun JF Tags: Acta Derm Venereol Source Type: research

Perception of Dermatology and Dermatologists Among Medical Students.
PMID: 30226530 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Ludriksone L, Tittelbach J, Elsner P Tags: Acta Derm Venereol Source Type: research

Phenotypic Features of Epidermolysis Bullosa Simplex due to KLHL24 Mutations in 3 Italian Cases.
PMID: 30226531 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: El Hachem M, Barresi S, Diociaiuti A, Boldrini R, Condorelli AG, Capoluongo E, Proto V, Scuvera G, Has C, Tartaglia M, Castiglia D Tags: Acta Derm Venereol Source Type: research

Progressive Nodular Histiocytosis with Large Nodules and a Bulky Mass.
PMID: 30226532 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 18, 2018 Category: Dermatology Authors: Kiyohara T, Makimura K, Miyamoto M, Shijimaya T, Nagano N, Nakamaru S, Tanimura H Tags: Acta Derm Venereol Source Type: research

Adverse Sexual Effects of Treatment with Finasteride or Dutasteride for Male Androgenetic Alopecia: A Systematic Review and Meta-analysis.
Abstract Treatment of male androgenetic alopecia with 5α-reductase inhibitors is efficacious. However, the risk of adverse sexual effects remains controversial. This systematic review and meta-analysis investigated the risk of adverse sexual effects due to treatment of androgenetic alopecia in male patients with finasteride, 1 mg/day, or dutasteride, 0.5 mg/day. Fifteen randomized double-blinded placebo-controlled trials (4,495 subjects) were meta-analysed. Use of 5α-reductase inhibitors carried a 1.57-fold risk of sexual dysfunction (95% confidence interval (95% CI) 1.19-2.08). The relative risk was 1...
Source: Acta Dermato-Venereologica - September 12, 2018 Category: Dermatology Authors: Lee S, Lee YB, Choe SJ, Lee WS Tags: Acta Derm Venereol Source Type: research

Bizarre Pigmented Lesion on the Scalp: A Quiz.
bba F PMID: 30206636 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 12, 2018 Category: Dermatology Authors: Micali G, Verzì AE, D'Agata E, Lacarrubba F Tags: Acta Derm Venereol Source Type: research

Predatory Journals in Dermatology: A Hidden Danger.
PMID: 30206637 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 12, 2018 Category: Dermatology Authors: Shalom G Tags: Acta Derm Venereol Source Type: research

Nail Involvement as a Predictor of Disease Severity in Paediatric Psoriasis: Follow-up Data from the Dutch ChildCAPTURE Registry.
Abstract Little is known about the relationship between nail psoriasis and psoriasis severity in children, and there has been no longitudinal assessment of psoriasis severity related to nail psoriasis. The aim of this study was to assess whether nail psoriasis could serve as a predictor for a more severe disease course. De-identified data were obtained from the Child-CAPTURE registry, a daily clinical practice cohort of children with psoriasis, from September 2008 to November 2015. Cross-sectional analyses were performed at baseline. Longitudinal data until 2-year follow-up were analysed by linear mixed models. Na...
Source: Acta Dermato-Venereologica - September 12, 2018 Category: Dermatology Authors: Bronckers IMGJ, Bruins FM, van Geel MJ, Groenewoud HMM, Kievit W, van de Kerkhof PCM, Pasch MC, de Jong EMGJ, Seyger MMB Tags: Acta Derm Venereol Source Type: research

Knowledge and Influence of Predatory Journals in Dermatology: A Pan-Austrian Survey.
g E Abstract The aim of this study was to assess the knowledge and influence of predatory journals in the field of dermatology in Austria. A total of 286 physicians (50.5% men) completed a questionnaire. The vast majority of subjects read scientific articles (n = 281, 98.3%) and took them into consideration in their clinical decision-making (n = 271, 98.5% of participants that regularly read scientific literature). Open access was known by 161 (56.3%), predatory journals by 84 (29.4%), and the Beall's list by 19 physicians (6.7%). A total of 117 participants (40.9%) had been challenged ...
Source: Acta Dermato-Venereologica - September 12, 2018 Category: Dermatology Authors: Richtig G, Richtig M, Hoetzenecker W, Saxinger W, Lange-Asschenfeldt B, Steiner A, Strohal R, Posch C, Bauer JW, Müllegger RR, Deinlein T, Sepp N, Volc-Platzer B, Nguyen VA, Schmuth M, Hoeller C, Muehlbacher E, Pregartner G, Richtig E Tags: Acta Derm Venereol Source Type: research

Langerhans Cell Histiocytosis with Lymph Node Involvment Presenting as Erythroderma.
PMID: 30182134 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 5, 2018 Category: Dermatology Authors: Zhu H, Ma Y, Sun L, Zhang R, Lv L, Wang A Tags: Acta Derm Venereol Source Type: research

Two Novel Mutations in the ERCC8 Gene in a Patient with Ultraviolet-sensitive Syndrome.
PMID: 30182135 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 5, 2018 Category: Dermatology Authors: Li Y, Zheng L, Chen F, Yao Z, Li M Tags: Acta Derm Venereol Source Type: research

Expression of n-MYC, NAMPT and SIRT1 in Basal Cell Carcinomas and their Cells of Origin.
Abstract Deregulated Hedgehog signalling is a driver of basal cell carcinomas. One effector of the Hedgehog pathway is n-MYC. c/n-MYC proteins, NAMPT and DBC1 are linked to SIRT1 in a positive feedback loop that may contribute to tumorigenesis of basal cell carcinoma. In 5 basal cell carcinoma types immunohistochemistry revealed n-MYC, NAMPT and SIRT1 expression. DBC1 was homogenously expressed in all epithelial cells. NAMPT, SIRT1 and c-MYC were expressed in the stratum basale of human and murine skin. In hair follicles NAMPT and SIRT1 were expressed together with c-MYC and n-MYC, except for the matrix, where n-M...
Source: Acta Dermato-Venereologica - September 5, 2018 Category: Dermatology Authors: Brandl L, Hartmann D, Kirchner T, Menssen A Tags: Acta Derm Venereol Source Type: research

Intergluteal Contour Deformity in Hidradenitis Suppurativa.
PMID: 30183056 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 5, 2018 Category: Dermatology Authors: Musumeci ML, Capuzzo G, Cammisuli B, Pesce A, Micali G Tags: Acta Derm Venereol Source Type: research

Acquired Partial Lipodystrophy Associated with Anti- Antibody-positive Adult-onset Dermatomyositis.
PMID: 30182133 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Shiraishi K, Tohyama M, Sayama K Tags: Acta Derm Venereol Source Type: research

Diagnostic Accuracy of Non-melanocytic Pink Flat Skin Lesions on the Legs: Dermoscopic and Reflectance Confocal Microscopy Evaluation.
M, Segura S Abstract Pink flat skin lesions on the legs in elderly people represent a diagnostic challenge due to the paucity of clinical and dermoscopic evidence. A prospective study of 114 pink flat lesions on the legs of 85 elderly patients was performed to describe the utility of reflectance confocal microscopy in this clinical context. Evaluation of clinical, dermoscopic and confocal parameters and calculation of diagnostic accuracy/sensitivity/specificity of each technique were carried out. Thirty-four benign and 80 malignant neoplasms were analysed. A correct clinical diagnosis was established in 49.1% of c...
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Gómez-Martín I, Moreno S, Duran X, Pujol RM, Segura S Tags: Acta Derm Venereol Source Type: research

The Number of FoxP3-positive Cells and Their Contacts with Tryptase-positive Mast Cells Increase in Tape-stripped Skin that Does not Develop the Isomorphic Psoriatic Reaction.
PMID: 30176038 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Suttle MM, Ritanen RL, Harvima IT Tags: Acta Derm Venereol Source Type: research

Direct Immunofluorescence of Mechanobullous Epidermolysis Bullosa Acquisita, Porphyria Cutanea Tarda and Pseudoporphyria.
Abstract Mechanobullous epidermolysis bullosa acquisita (mEBA) can have a clinical presentation that is very similar to other blistering diseases, such as porphyria cutanea tarda (PCT) and pseudoporphyria. Direct immunofluorescence is an important feature in the diagnosis of mEBA, although features that overlap with PCT and pseudoporphyria have been reported. This retrospective observational study investigated whether direct immunofluorescence can discriminate mEBA from PCT and pseudoporphyria. Biopsies of 13 patients with mEBA, 10 with PCT and 10 with pseudoporphyria were included. In 7 cases of PCT and 4 of pseu...
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: de Groot HJ, Jonkman MF, Pas HH, Diercks GFH Tags: Acta Derm Venereol Source Type: research

A Myxoid Fibrotic Reaction Pattern is Associated with Metastatic Risk in Cutaneous Squamous Cell Carcinoma.
This study aimed to examine the different stromal fibrotic patterns as markers of metastatic risk. We performed a multicenter retrospective study that included 102 cutaneous squamous cell carcinomas (52 non-metastatic and 50 metastatic carcinomas). Clinical and histopathological data were registered. The fibrotic reaction pattern was classified as mature, intermediate or immature depending on the presence of keloid-like collagen and myxoid stroma. The immature pattern (areas characterized by myxoid changes with no inflammation) was observed in 18 samples and its presence was significantly associated with immuno-suppression...
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Hernández-Ruiz E, Hernández-Muñoz I, Masferrer E, Ferrándiz-Pulido C, Andrades E, Gimeno J, Duran X, García-Patos V, Pujol RM, Toll A Tags: Acta Derm Venereol Source Type: research

Disseminated Erythematous Papules and Pustules: A Quiz.
PMID: 30176041 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Fujita Y, Shiiya C, Inamura-Takashima Y, Nomura T, Shibaki A, Shimizu H Tags: Acta Derm Venereol Source Type: research

Two Cases of Acute Febrile Neutrophilic Dermatosis Thought to be Caused by Topical Clindamycin.
PMID: 30176042 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Nitta K, Kano Y, Ushigome Y, Hayakawa J, Shiohara T Tags: Acta Derm Venereol Source Type: research

Clinical Experience of Overnight use of a Temperature-controlled Airflow Device in a Teenager with Severe Atopic Dermatitis.
ing; PMID: 30176043 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - September 3, 2018 Category: Dermatology Authors: Theodosiou G, Svensson Å Tags: Acta Derm Venereol Source Type: research