Serum uric acid to hdl cholesterol ratio is associated with diabetic control in new onset type 2 diabetic population
Acta Clin Croat. 2023 Aug;62(2):277-282. doi: 10.20471/acc.2023.62.02.04.ABSTRACTSince uric acid to HDL cholesterol ratio (UHR) is proposed as a novel predictor of metabolic and inflammatory disorders, we aimed to study UHR levels in patients with new onset type 2 diabetes mellitus (T2DM) and compare them to those in healthy controls. Patients with new onset T2DM were enrolled and control subjects were volunteers to participate without any established diseases. Laboratory data including UHR, fasting blood glucose (FBG) and glycated hemoglobin (HbA1c) were compared. The mean UHR of the T2DM and control groups was 16±8% and...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Mehmet Ali Kosekli Gulali Aktas Source Type: research
Understanding demographic and epidemiologic characteristics of hospitalized immigrant female patients: a retrospective observational study
Acta Clin Croat. 2023 Aug;62(2):323-329. doi: 10.20471/acc.2023.62.02.10.ABSTRACTPrecise epidemiologic and demographic characteristics of immigrant women admitted to gynecology or obstetrics departments are rarely explored. The aim of this retrospective observational study was to analyze the epidemiologic and demographic characteristics of immigrant female patients hospitalized between 2012 and 2017 in one maternity hospital in south-west Slovenia. Clinical data retrieved from hospital electronic information system were used to analyze these characteristics. In the mentioned period, 605 immigrant women were hospitalized, m...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Igor Karnju š Sabina Li čen Mirko Prosen Source Type: research
Uromodulin - a link between sodium excretion and alteration in circadian blood pressure pattern in prehypertensives
Acta Clin Croat. 2023 Aug;62(2):313-322. doi: 10.20471/acc.2023.62.02.09.ABSTRACTAlthough changes in dietary sodium intake alter blood pressure (BP) in salt-sensitive individuals, pathophysiological mechanisms are still unknown. It has been reported that uromodulin is involved in sodium tubular transport, and genome-wide association studies pointed to UMOD gene as one of the most important gene candidates for arterial hypertension. Our aim was to analyze urinary uromodulin, salt intake and BP in 326 young middle-aged subjects (mean age 36±8 years, 49.4% male). In a subgroup of 175 individuals, ambulatory blood pressure mo...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Josipa Josipovi ć Livija Šimičević Živka Dika Nikola Bulj Mislav Vrsalovi ć Bojan Jelakovi ć Source Type: research
Treatment of congenital laryngeal cysts in newborns
We present a case series of five neonates treated for congenital laryngeal cysts during the 2011-2017 period at our pediatric tertiary care hospital. Patient age ranged from one day to 14 days. All patients had unilateral cysts. After surgical excision, burning of the walls of the cysts was performed by a CO2 laser. In one case, after four months, a recurrent cyst appeared, and re-operation was performed. Our relatively small case series indicates that symptoms such as stridor and labored breathing can occur already during the first days of life and potentially endanger the patient's life. Complete excision of the cyst and...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Ivan Baljo šević Aleksandar Peri ć Aleksandar Sovti ć Slavi ša Antić Source Type: research
The effect of palpebral fissure height in primary gaze position on tear film stability
In conclusion, an enlarged exposed ocular surface due to higher palpebral fissure height in healthy individual's primary gaze position negatively affects tear film stability expressed by TBUT.PMID:38549607 | PMC:PMC10969636 | DOI:10.20471/acc.2023.62.02.05 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Ana Čović Igor Petri ček Martina Tomi ć Source Type: research
Salivary melatonin values significantly correlate with reduced quality of life in chronic spontaneous urticaria patients: a pilot study
This study was the first to analyze melatonin in CSU patients, also suggesting a possible new therapeutic option for the treatment of CSU.PMID:38549588 | PMC:PMC10969637 | DOI:10.20471/acc.2023.62.02.17 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Iva Be šlić Alen Vrtari ć Ante Be šlić Ivana Škrinjar Danijel Crnkovi ć Liborija Lugovi ć-Mihić Source Type: research
Primary angiitis of the central nervous system - a diagnostic challenge
Acta Clin Croat. 2023 Aug;62(2):355-361. doi: 10.20471/acc.2023.62.02.14.ABSTRACTPrimary angiitis of the central nervous system (PACNS) is a rare and severe disease confined to the central nervous system, i.e., the brain and spinal cord. The etiology, pathogenesis and immune mechanism of PACNS have not yet been completely elucidated. The diagnosis is challenging; it is based upon constellation of clinical picture, cerebrospinal fluid analysis, imaging methods or tissue biopsy as the gold standard. In differential diagnosis of PACNS, it is necessary to rule out infectious, malignant or systemic inflammatory diseases, as wel...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Jo ško Mitrović Majda Golob Ines Lazibat Source Type: research
Opioid free general anesthesia in clinical practice - a review article
Acta Clin Croat. 2023 Aug;62(2):362-367. doi: 10.20471/acc.2023.62.02.15.ABSTRACTCurrently, enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways with the goal to achieve early patient recovery after surgery with minimal postoperative complications. According to studies, opioid free general anesthesia has many perioperative benefits and should be part of the ERAS protocols in specific surgical and patient indications. Opioid free general anesthesia is a multimodal balanced technique that is based on the concept that opioids are not used preoperatively or intraoperatively until the pati...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Sanja Sakan Žana Turudić Sanja Peremin Andrej Šribar Nata ša Sojčić Marcela Čučković Domagoj Vergles Jasminka Per šec Source Type: research
Avascular overhanging bleb reduction with modified sutureless technique
In conclusion, this less invasive technique preserves better bleb function without ripping the surrounding ischemic tissue. The procedure is safe and easy to perform, with less surgical time and fast recovery.PMID:38549591 | PMC:PMC10969647 | DOI:10.20471/acc.2023.62.02.18 (Source: Acta Clinica Croatica)
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Marta Pazos Ana Mart ínez-Palmer Vladimir Poposki Source Type: research
Impact of air transport on blood sample quality
Acta Clin Croat. 2023 Aug;62(2):345-354. doi: 10.20471/acc.2023.62.02.13.ABSTRACTThe aim of this study was to establish the impact of air transport on blood samples packaged with and without cooling elements and effect of outdoor temperature on sample quality. Venous samples from 38 blood donors in winter and 36 in summer were tested for hemolysis and complete blood count. One tube per subject was kept in controlled conditions at +4 °C. Two sets of tubes were sent by plane from Zagreb to Brussels, one with and one without cooling elements, and another two sets were sent to London following the same principle. Packages wit...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Irena Juki ć Tomislav Vuk Zvonimir Maji ć Ivanka Batarilo Jasna Bingulac-Popovi ć Ana He ćimović Marina Lampalo Maja Strauss Patko Source Type: research
Intranasal pleomorphic adenoma arising from the lateral nasal wall
Acta Clin Croat. 2023 Aug;62(2):387-390. doi: 10.20471/acc.2023.62.02.20.ABSTRACTPleomorphic adenoma is very rare in the sinonasal region, with the most common localization on the nasal septum, followed by lateral nasal wall. In the case presented, a 72-year-old woman was complaining of the right sided nasal obstruction without any other symptoms. The symptom started a year before and increased progressively. Anterior rhinoscopy revealed a mucosa-covered, smooth-surfaced, soft, polypoid, pale, grayish-pink in color mass in the right nasal cavity, approximately 2x2 cm in size. Nasal endoscopy showed the mass to have a broad...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Ljiljana Jovan čević Aleksandra Fejsa Levakov Bojana Jovan čević Source Type: research
Refractory guillain-barr É syndrome in a patient with asymptomatic multiple myeloma successfully treated with low-dose rituximab
Acta Clin Croat. 2023 Aug;62(2):382-386. doi: 10.20471/acc.2023.62.02.19.ABSTRACTDespite being extremely rare, Guillain-Barré syndrome (GBS) has been recognized as a neurological complication of multiple myeloma, with variable responses to plasmapheresis (PEX), intravenous immunoglobulins (IVIG), and anti-myeloma therapies. In this paper, we report a case of a female patient with asymptomatic multiple myeloma (aMM) who initially presented as PEX- and IVIG-refractory GBS. After failure of PEX, IVIG, and anti-myeloma therapy (bortezomib, melphalan, and prednisone), the patient was eventually successfully treated with low-do...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Ivan Kre čak Velka Gveri ć-Krečak Source Type: research
The concentration of interleukin 6 and tumor necrosis factor alpha in saliva and blood of patients with inactive multiple sclerosis and coexisting hashimoto's thyroiditis
Acta Clin Croat. 2023 Aug;62(2):339-344. doi: 10.20471/acc.2023.62.02.12.ABSTRACTThe concentration of interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) in the blood is higher in patients with active multiple sclerosis (MS) compared to those with inactive disease. The concentration of IL-6 and TNF-α in the blood is higher in patients with Hashimoto's thyroiditis (HT) compared to those with a healthy thyroid. The aim of the study was to assess whether serum IL-6 and TNF-α levels correlated with saliva in patients with inactive MS and whether there was a difference in these groups of patients depending of thyroi...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Ines Šiško Markoš Maja Franceschi Valentina Vidranski Pave Marko š Tomislav Juki ć Ana Fr öbe Vanja Ba šić Kes Source Type: research
Characteristics of hearing recovery in children with chronic otitis media with effusion after ventilation tube insertion
This study also investigated whether there was a difference in the mean hearing improvement between the left and right ear, how many months passed before recovery of eustachian tube function, and how long the aeration of the middle ear lasted. The children included in the study were between six and twelve years of age, diagnosed with COME by audiological processing (type B tympanometric recording and conductive hearing loss up to 40 dB on pure tone audiometry) and underwent surgical insertion of ventilation tubes in both ears. Patient data included preoperative tympanometric records, preoperative and postoperative tone aud...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Anita D želalija Marisa Klan čnik Ozren Marin Krni ć Source Type: research
The use of tranexamic acid in dermatology
Acta Clin Croat. 2023 Aug;62(2):368-372. doi: 10.20471/acc.2023.62.02.16.ABSTRACTTranexamic acid is a synthetic derivative of the amino acid lysine, an antifibrinolytic that is primarily used to reduce bleeding in surgery, trauma, and dental procedures. Its anti-inflammatory and anti-angiogenic properties, as well as its ability to suppress melanogenesis have enabled it to be used in dermatology in the treatment of skin conditions such as melasma, acne, post-inflammatory hyperpigmentation, rosacea and angioedema. Tranexamic acid can be used by various routes of administration including oral, topical and intradermal injecti...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Klara Ga ćina An đela Krstanović Ćosić Source Type: research
