Ghanaian women ’s experiences of unsuccessful in-vitro fertilisation treatment, unravelling their meanings: a Heideggerian hermeneutic phenomenological study
Women having experienced infertility over a period usually decide on an option for an invitro fertilisation treatment (IVF). However, in the quest to seek help and to be part of motherhood, they sometimes beco... (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - March 20, 2024 Category: OBGYN Authors: Amoah Vida Maame Kissiwaa and Nicola Fouch é Tags: Research Source Type: research

Age at menarche and risk of ovarian hyperstimulation syndrome in women undergoing IVF/ICSI cycles: a retrospective cohort study
Conclusion Menarche age earlier than 12 years may increase the OHSS risk in women aged ≤30 years through the mediation of AFC. More prospective studies are required to verify the results. (Source: BMJ Open)
Source: BMJ Open - February 15, 2024 Category: General Medicine Authors: Wang, Q., Tang, X., Lv, X., Meng, X., Geng, L., Zhong, Z., Ding, Y., Li, T., Wan, Q. Tags: Open access, Epidemiology Source Type: research

Comparison of embryo quality and pregnancy outcomes for patients with low ovarian reserve in natural cycles and mildly stimulated cycles: a cohort study
CONCLUSION: Natural cycles with appropriately timed oocyte retrieval may present a valuable option for patients with low ovarian reserve.PMID:38263614 | DOI:10.1080/01443615.2024.2303693 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - January 24, 2024 Category: OBGYN Authors: Rui-Ying Yuan Sen Li Xie Feng Xiao-Long Li Xiao-Ting Lin Fu-Min Gao Hai-Jing Zhu Yong-Shi Li Yan-Chu Li Xiang-Hong Ou Source Type: research

Case-controlled study of tuberculosis in in-vitro fertilisation-embryo transfer and natural pregnancy
To improve the understanding of the clinical features and imaging characteristics of pregnant women with and without in-vitro fertilisation-embryo transfer combined with pulmonary tuberculosis (TB). (Source: BMC Pregnancy and Childbirth)
Source: BMC Pregnancy and Childbirth - January 23, 2024 Category: OBGYN Authors: Jia-Lu Wei, Le Zhang, Yan-Ling Xu, Wei Gan, Min Qi, Xu-Wen Fu and Xiang Li Tags: Research Source Type: research

Sperm selection by zona adhesion improves assisted reproductive treatment outcomes
Discussion and conclusionThe application of solubilised zonae pellucidae in the sperm selection for ICSI benefits ART outcomes in couples with unexplained infertility. Moreover, sperm –zona selection significantly reduces the risk of miscarriages. (Source: Andrology)
Source: Andrology - January 16, 2024 Category: Urology & Nephrology Authors: Rumiana Ganeva, Dimitar Parvanov, Nina Vidolova, Maria Handzhiyska, Margarita Ruseva, Magdaleva Vasileva, Kristina Nikolova, Ivka Ivanova, Miray Shaban, Joanna Shabarkova, Rayna Hristova, Milena Miladinova, Georgi Stamenov Tags: ORIGINAL ARTICLE Source Type: research

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)
CONCLUSIONS: We did not find that tailoring the FSH dose in any particular ORT population (low, normal, high ORT) affected live birth/ongoing pregnancy rates, but we could not rule out differences, due to sample size limitations. Low-certainty evidence suggests that it is unclear if ORT-based individualisation leads to an increase in live birth/ongoing pregnancy rates compared to a policy of giving all women 150 IU. The confidence interval is consistent with an increase of up to around six percentage points with ORT-based dosing (e.g. from 25% to 31%) or a very small decrease (< 1%). A difference of this magnitude could...
Source: Cochrane Database of Systematic Reviews - January 4, 2024 Category: General Medicine Authors: Olina Ngwenya Sarah F Lensen Andy Vail Ben Willem J Mol Frank J Broekmans Jack Wilkinson Source Type: research

Individualised gonadotropin dose selection using markers of ovarian reserve for women undergoing in vitro fertilisation plus intracytoplasmic sperm injection (IVF/ICSI)
CONCLUSIONS: We did not find that tailoring the FSH dose in any particular ORT population (low, normal, high ORT) affected live birth/ongoing pregnancy rates, but we could not rule out differences, due to sample size limitations. Low-certainty evidence suggests that it is unclear if ORT-based individualisation leads to an increase in live birth/ongoing pregnancy rates compared to a policy of giving all women 150 IU. The confidence interval is consistent with an increase of up to around six percentage points with ORT-based dosing (e.g. from 25% to 31%) or a very small decrease (< 1%). A difference of this magnitude could...
Source: Cochrane Database of Systematic Reviews - January 4, 2024 Category: General Medicine Authors: Olina Ngwenya Sarah F Lensen Andy Vail Ben Willem J Mol Frank J Broekmans Jack Wilkinson Source Type: research

Efficacy and safety of recombinant human granulocyte colony-stimulating factor in patients with poor ovarian response: protocol for a multicentre, randomised, controlled trial
This study will provide new information about G-CSF efficacy among patients with POR undergoing IVF/ICSI and can help improve ovum quality and maturity. Clinical trials on this subject are deficient in China; therefore, a well-designed randomised trial is needed to determine the ability of G-CSF to improve ovum quality and maturity to facilitate conception among women with POR treated with IVF/ICSI. Trial registration number ChiCTR2200062412. (Source: BMJ Open)
Source: BMJ Open - December 30, 2023 Category: General Medicine Authors: Zeng, X., Du, L., Yang, H., Wang, F. Tags: Open access, Reproductive medicine Source Type: research

Coculture with porcine luteal cells during in vitro porcine oocyte maturation affects lipid content, cortical reaction and zona pellucida ultrastructure
CONCLUSIONS: The coculture of COC with PLC affects the metabolism of the oocyte and benefits monospermic penetration and embryo development.IMPLICATIONS: The coculture system with PLC could be an alternative for the conventional maturation medium in pigs.PMID:38096792 | DOI:10.1071/RD23150 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - December 14, 2023 Category: Reproduction Medicine Authors: G M Teplitz M S Lorenzo P R Cruzans G B Olea D F Salamone A Bastien C Robert M A Sirard D M Lombardo Source Type: research

Coculture with porcine luteal cells during in vitro porcine oocyte maturation affects lipid content, cortical reaction and zona pellucida ultrastructure
CONCLUSIONS: The coculture of COC with PLC affects the metabolism of the oocyte and benefits monospermic penetration and embryo development.IMPLICATIONS: The coculture system with PLC could be an alternative for the conventional maturation medium in pigs.PMID:38096792 | DOI:10.1071/RD23150 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - December 14, 2023 Category: Reproduction Medicine Authors: G M Teplitz M S Lorenzo P R Cruzans G B Olea D F Salamone A Bastien C Robert M A Sirard D M Lombardo Source Type: research

Coculture with porcine luteal cells during in vitro porcine oocyte maturation affects lipid content, cortical reaction and zona pellucida ultrastructure
CONCLUSIONS: The coculture of COC with PLC affects the metabolism of the oocyte and benefits monospermic penetration and embryo development.IMPLICATIONS: The coculture system with PLC could be an alternative for the conventional maturation medium in pigs.PMID:38096792 | DOI:10.1071/RD23150 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - December 14, 2023 Category: Reproduction Medicine Authors: G M Teplitz M S Lorenzo P R Cruzans G B Olea D F Salamone A Bastien C Robert M A Sirard D M Lombardo Source Type: research

Coculture with porcine luteal cells during in vitro porcine oocyte maturation affects lipid content, cortical reaction and zona pellucida ultrastructure
CONCLUSIONS: The coculture of COC with PLC affects the metabolism of the oocyte and benefits monospermic penetration and embryo development.IMPLICATIONS: The coculture system with PLC could be an alternative for the conventional maturation medium in pigs.PMID:38096792 | DOI:10.1071/RD23150 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - December 14, 2023 Category: Reproduction Medicine Authors: G M Teplitz M S Lorenzo P R Cruzans G B Olea D F Salamone A Bastien C Robert M A Sirard D M Lombardo Source Type: research

Coculture with porcine luteal cells during in vitro porcine oocyte maturation affects lipid content, cortical reaction and zona pellucida ultrastructure
CONCLUSIONS: The coculture of COC with PLC affects the metabolism of the oocyte and benefits monospermic penetration and embryo development.IMPLICATIONS: The coculture system with PLC could be an alternative for the conventional maturation medium in pigs.PMID:38096792 | DOI:10.1071/RD23150 (Source: Reproduction, Fertility, and Development)
Source: Reproduction, Fertility, and Development - December 14, 2023 Category: Reproduction Medicine Authors: G M Teplitz M S Lorenzo P R Cruzans G B Olea D F Salamone A Bastien C Robert M A Sirard D M Lombardo Source Type: research