EFFORT study: Comparing impact of operation and assisted reproductive technologies on fertility for women with deep infiltrating endometriosis - study protocol for a multicentre randomised trial
Introduction Deep infiltrating endometriosis (DIE) affecting the rectum or sigmoid colon is associated with infertility, severe pain and decreased quality of life. As most women with DIE are young, many have a pregnancy intention. Treatment possibilities of endometriosis-associated infertility are surgery or assisted reproductive technologies (ART). However, no studies have compared the two interventions directly. Therefore, this study aims to determine the cumulative pregnancy rate (CPR) and the live birth rate (LBR) after first-line surgery compared with first-line ART for women with rectosigmoid DIE and a pregnancy inte...
Source: BMJ Open - April 11, 2022 Category: General Medicine Authors: Raos, M., Roman, H., Seyer-Hansen, M., Kesmodel, U. S., Knudsen, U. B. Tags: Open access Obstetrics and gynaecology Source Type: research

FSFI score and timing of tubal ligation in patients: preliminary results of an online survey
DiscussionBesides the obvious benefit of a low pearl index, tubal ligation may contribute to reduce the risk of female sexual dysfunction in the mid and long term. Informed consent is essential for the surgeon and patient to weigh up the risks and benefits individually including possible future perspectives on family planning. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 10, 2022 Category: OBGYN Source Type: research

Sperm DNA damage compromises embryo development, but not oocyte fertilisation in pigs
CONCLUSION: Considering all these findings, this work sets a useful model to study how SDF negatively influences fertility.PMID:35365220 | DOI:10.1186/s40659-022-00386-2 (Source: Cell Research)
Source: Cell Research - April 2, 2022 Category: Cytology Authors: Yentel Mateo-Otero Marc Llavanera Sandra Recuero Ariadna Delgado-Berm údez Isabel Barranco Jordi Ribas-Maynou Marc Yeste Source Type: research

Intrauterine insemination  + controlled ovarian hyperstimulation versus in vitro fertilisation in unexplained infertility: a systematic review and meta-analysis
ConclusionFurther research using a standardised treatment protocol and taking into account important prognostic variables and cumulative live birth rates from fresh IVF and all sibling frozen embryos is required to further guide clinical practice. (Source: Archives of Gynecology and Obstetrics)
Source: Archives of Gynecology and Obstetrics - April 1, 2022 Category: OBGYN Source Type: research