EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial
This study aims to assess the effect of MRA administration in the early phase of kidney transplantation (KT) among recipients of ECD grafts on mid-term graft function.Methods/designThis is a multicenter, double-blind, placebo-controlled, randomized clinical trial. Patients on hemodialysis and undergoing a single or a dual KT from an ECD will be eligible for inclusion. We plan to randomize 132 patients. Included patients will be randomized (1:1) to receive either eplerenone 25  mg every 12 h during 4 days (the first dose being administered just prior to KT) or placebo. The primary outcome is graft function at...
Source: Trials - October 30, 2018 Category: Research Source Type: clinical trials

Pediatric Risk of Hypothyroidism With Iodinated Contrast Media
Condition:   Hypothyroidism Interventions:   Drug: Iohexol;   Drug: Iodixanol;   Drug: Iopromide Sponsors:   GE Healthcare;   Bayer;   Duke Clinical Research Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 15, 2018 Category: Research Source Type: clinical trials

A Study of Lanabecestat in Participants With Severe Kidney Impairment Compared to Healthy Participants
Condition:   Renal Insufficiency Interventions:   Drug: Lanabecestat;   Drug: Iohexol Sponsors:   Eli Lilly and Company;   AstraZeneca Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 4, 2018 Category: Research Source Type: clinical trials

Dosing Iodinated Contrast Media According to Lean vs. Total Body Weight
Condition:   Contrast Media Dosing Intervention:   Drug: Iohexol Sponsor:   Nova Scotia Health Authority Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 30, 2018 Category: Research Source Type: clinical trials

Measurement of Iohexol Plasma Clearance in Patients Leaving ICU After Acute Renal Failure
Condition:   Acute Renal Failure Intervention:   Drug: IOHEXOL Sponsor:   University Hospital, Angers Not yet recruiting - verified November 2016 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 3, 2016 Category: Research Source Type: clinical trials