Divergent perspectives: exploring the relationships between St. George ’s Respiratory Questionnaire and outcome measures in systemic sclerosis–associated interstitial lung disease
ConclusionsOur study reveals varying degrees of correlation between SGRQ and distinct outcome measures. Given the incomplete alignment of SGRQ with other outcome measures, an integrative approach utilizing existing criteria as complementary tools is recommended.Key Points•Patient-reported outcome measures (PROMs) derive from patients ’ subjective evaluations of the impact of the disease on their daily activities, social interactions, and psychological well-being.•PROMs frequently serve as outcome measures in randomized controlled trials, yet conflicting findings have emerged in relation to primary outcomes.•This st...
Source: Clinical Rheumatology - April 4, 2024 Category: Rheumatology Source Type: research

Characteristics of chest high-resolution computed tomography in patients with anti-aminoacyl-tRNA synthetase antibody-positive interstitial lung disease
CONCLUSIONS: This retrospective study demonstrated that ARS-ILD patients, regardless of myositis symptoms, most often showed the NSIP pattern on HRCT, as previously reported. However, unlike previous reports, the UIP pattern on HRCT was not rare.PMID:38567566 | DOI:10.36141/svdld.v41i1.14144 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Masato Mima Seidai Sato Takayoshi Shinya Nobuhito Naito Takatoshi Shoji Saki Harada Ryoko Suzue Kojin Murakami Kazuya Koyama Yasuhiko Nishioka Source Type: research

Prognostic significance of antifibrotic agents in idiopathic pulmonary fibrosis after initiation of long-term oxygen therapy
CONCLUSION: In IPF patients who were introduced LTOT, treatment with antifibrotic agents was the independent factor for favorable survival. Treatment with antifibrotic agents may improve prognosis of IPF even after initiation of LTOT.PMID:38567555 | DOI:10.36141/svdld.v41i1.15264 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Mayuko Ishiwari Yuta Kono Yuki Togashi Kenichi Kobayashi Ryota Kikuchi Mariko Kogami Shinji Abe Source Type: research

Tension Pneumomediastinum in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease: A Case Report and Literature Review
Intern Med. 2024 Apr 2. doi: 10.2169/internalmedicine.3418-23. Online ahead of print.ABSTRACTAnti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM)-associated interstitial lung disease (ILD) can sometimes be complicated by pneumomediastinum, although tension pneumomediastinum is extremely rare. We herein report a case of anti-MDA5 antibody-positive DM-ILD that worsened subcutaneous and mediastinal emphysema during treatment. Hypotension and worsening respiratory failure were observed on day 20 of treatment. Mediastinal drainage under video-assisted thoracoscopic surgery promptly impro...
Source: Internal Medicine - April 3, 2024 Category: Internal Medicine Authors: Hiroko Okabayashi Seiya Nakashima Kosuke Fujino Miyu Imai Shohei Hamada Aiko Masunaga Hidenori Ichiyasu Makoto Suzuki Takuro Sakagami Source Type: research

Characteristics of chest high-resolution computed tomography in patients with anti-aminoacyl-tRNA synthetase antibody-positive interstitial lung disease
CONCLUSIONS: This retrospective study demonstrated that ARS-ILD patients, regardless of myositis symptoms, most often showed the NSIP pattern on HRCT, as previously reported. However, unlike previous reports, the UIP pattern on HRCT was not rare.PMID:38567566 | DOI:10.36141/svdld.v41i1.14144 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Masato Mima Seidai Sato Takayoshi Shinya Nobuhito Naito Takatoshi Shoji Saki Harada Ryoko Suzue Kojin Murakami Kazuya Koyama Yasuhiko Nishioka Source Type: research

Prognostic significance of antifibrotic agents in idiopathic pulmonary fibrosis after initiation of long-term oxygen therapy
CONCLUSION: In IPF patients who were introduced LTOT, treatment with antifibrotic agents was the independent factor for favorable survival. Treatment with antifibrotic agents may improve prognosis of IPF even after initiation of LTOT.PMID:38567555 | DOI:10.36141/svdld.v41i1.15264 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Mayuko Ishiwari Yuta Kono Yuki Togashi Kenichi Kobayashi Ryota Kikuchi Mariko Kogami Shinji Abe Source Type: research

Tension Pneumomediastinum in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease: A Case Report and Literature Review
Intern Med. 2024 Apr 2. doi: 10.2169/internalmedicine.3418-23. Online ahead of print.ABSTRACTAnti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM)-associated interstitial lung disease (ILD) can sometimes be complicated by pneumomediastinum, although tension pneumomediastinum is extremely rare. We herein report a case of anti-MDA5 antibody-positive DM-ILD that worsened subcutaneous and mediastinal emphysema during treatment. Hypotension and worsening respiratory failure were observed on day 20 of treatment. Mediastinal drainage under video-assisted thoracoscopic surgery promptly impro...
Source: Internal Medicine - April 3, 2024 Category: Internal Medicine Authors: Hiroko Okabayashi Seiya Nakashima Kosuke Fujino Miyu Imai Shohei Hamada Aiko Masunaga Hidenori Ichiyasu Makoto Suzuki Takuro Sakagami Source Type: research

Characteristics of chest high-resolution computed tomography in patients with anti-aminoacyl-tRNA synthetase antibody-positive interstitial lung disease
CONCLUSIONS: This retrospective study demonstrated that ARS-ILD patients, regardless of myositis symptoms, most often showed the NSIP pattern on HRCT, as previously reported. However, unlike previous reports, the UIP pattern on HRCT was not rare.PMID:38567566 | DOI:10.36141/svdld.v41i1.14144 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Masato Mima Seidai Sato Takayoshi Shinya Nobuhito Naito Takatoshi Shoji Saki Harada Ryoko Suzue Kojin Murakami Kazuya Koyama Yasuhiko Nishioka Source Type: research

Prognostic significance of antifibrotic agents in idiopathic pulmonary fibrosis after initiation of long-term oxygen therapy
CONCLUSION: In IPF patients who were introduced LTOT, treatment with antifibrotic agents was the independent factor for favorable survival. Treatment with antifibrotic agents may improve prognosis of IPF even after initiation of LTOT.PMID:38567555 | DOI:10.36141/svdld.v41i1.15264 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Mayuko Ishiwari Yuta Kono Yuki Togashi Kenichi Kobayashi Ryota Kikuchi Mariko Kogami Shinji Abe Source Type: research

Tension Pneumomediastinum in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease: A Case Report and Literature Review
Intern Med. 2024 Apr 2. doi: 10.2169/internalmedicine.3418-23. Online ahead of print.ABSTRACTAnti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM)-associated interstitial lung disease (ILD) can sometimes be complicated by pneumomediastinum, although tension pneumomediastinum is extremely rare. We herein report a case of anti-MDA5 antibody-positive DM-ILD that worsened subcutaneous and mediastinal emphysema during treatment. Hypotension and worsening respiratory failure were observed on day 20 of treatment. Mediastinal drainage under video-assisted thoracoscopic surgery promptly impro...
Source: Internal Medicine - April 3, 2024 Category: Internal Medicine Authors: Hiroko Okabayashi Seiya Nakashima Kosuke Fujino Miyu Imai Shohei Hamada Aiko Masunaga Hidenori Ichiyasu Makoto Suzuki Takuro Sakagami Source Type: research

Characteristics of chest high-resolution computed tomography in patients with anti-aminoacyl-tRNA synthetase antibody-positive interstitial lung disease
CONCLUSIONS: This retrospective study demonstrated that ARS-ILD patients, regardless of myositis symptoms, most often showed the NSIP pattern on HRCT, as previously reported. However, unlike previous reports, the UIP pattern on HRCT was not rare.PMID:38567566 | DOI:10.36141/svdld.v41i1.14144 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Masato Mima Seidai Sato Takayoshi Shinya Nobuhito Naito Takatoshi Shoji Saki Harada Ryoko Suzue Kojin Murakami Kazuya Koyama Yasuhiko Nishioka Source Type: research

Prognostic significance of antifibrotic agents in idiopathic pulmonary fibrosis after initiation of long-term oxygen therapy
CONCLUSION: In IPF patients who were introduced LTOT, treatment with antifibrotic agents was the independent factor for favorable survival. Treatment with antifibrotic agents may improve prognosis of IPF even after initiation of LTOT.PMID:38567555 | DOI:10.36141/svdld.v41i1.15264 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Mayuko Ishiwari Yuta Kono Yuki Togashi Kenichi Kobayashi Ryota Kikuchi Mariko Kogami Shinji Abe Source Type: research

Tension Pneumomediastinum in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease: A Case Report and Literature Review
Intern Med. 2024 Apr 2. doi: 10.2169/internalmedicine.3418-23. Online ahead of print.ABSTRACTAnti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM)-associated interstitial lung disease (ILD) can sometimes be complicated by pneumomediastinum, although tension pneumomediastinum is extremely rare. We herein report a case of anti-MDA5 antibody-positive DM-ILD that worsened subcutaneous and mediastinal emphysema during treatment. Hypotension and worsening respiratory failure were observed on day 20 of treatment. Mediastinal drainage under video-assisted thoracoscopic surgery promptly impro...
Source: Internal Medicine - April 3, 2024 Category: Internal Medicine Authors: Hiroko Okabayashi Seiya Nakashima Kosuke Fujino Miyu Imai Shohei Hamada Aiko Masunaga Hidenori Ichiyasu Makoto Suzuki Takuro Sakagami Source Type: research

Characteristics of chest high-resolution computed tomography in patients with anti-aminoacyl-tRNA synthetase antibody-positive interstitial lung disease
CONCLUSIONS: This retrospective study demonstrated that ARS-ILD patients, regardless of myositis symptoms, most often showed the NSIP pattern on HRCT, as previously reported. However, unlike previous reports, the UIP pattern on HRCT was not rare.PMID:38567566 | DOI:10.36141/svdld.v41i1.14144 (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)
Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases - April 3, 2024 Category: Respiratory Medicine Authors: Masato Mima Seidai Sato Takayoshi Shinya Nobuhito Naito Takatoshi Shoji Saki Harada Ryoko Suzue Kojin Murakami Kazuya Koyama Yasuhiko Nishioka Source Type: research