Validity of bioelectric impedance analysis for body composition assessment in interstitial lung disease patients
CONCLUSION: BC estimated by BIA showed good agreement and reliability with DEXA measurements. In the absence of this method, BIA can replace the DEXA technique for body composition assessment.PMID:38501791 | DOI:10.20960/nh.04882 (Source: Nutricion Hospitalaria)
Source: Nutricion Hospitalaria - March 19, 2024 Category: Nutrition Authors: Gabriela Rosaura Garc ía Del Valle-Alegría Iv án Armando Osuna-Padilla Ana Luc ía Gómez-Rodríguez Aime Alarc ón-Dionet Zobeida Rodriguez-D íaz Ivette Buend ía-Roldán Source Type: research

Drug-induced interstitial lung disease: a narrative review of a clinical conundrum
Expert Rev Respir Med. 2024 Mar 19:1-17. doi: 10.1080/17476348.2024.2329612. Online ahead of print.ABSTRACTINTRODUCTION: Drug-induced interstitial lung disease (DI-ILD) is increasing in incidence, due to the use of many new drugs across a broad range of cancers and chronic inflammatory diseases. The presentation and onset of DI-ILD are variable even for the same drug across different individuals. Clinical suspicion is essential for identifying these conditions, with timely drug cessation an important determinant of outcomes.AREAS COVERED: This review provides a comprehensive and up-to-date summary of epidemiology, risk fac...
Source: Expert Review of Respiratory Medicine - March 19, 2024 Category: Respiratory Medicine Authors: Megan Harrison Grace Kavanagh Tamera J Corte Lauren K Troy Source Type: research

Validity of bioelectric impedance analysis for body composition assessment in interstitial lung disease patients
CONCLUSION: BC estimated by BIA showed good agreement and reliability with DEXA measurements. In the absence of this method, BIA can replace the DEXA technique for body composition assessment.PMID:38501791 | DOI:10.20960/nh.04882 (Source: Nutricion Hospitalaria)
Source: Nutricion Hospitalaria - March 19, 2024 Category: Nutrition Authors: Gabriela Rosaura Garc ía Del Valle-Alegría Iv án Armando Osuna-Padilla Ana Luc ía Gómez-Rodríguez Aime Alarc ón-Dionet Zobeida Rodriguez-D íaz Ivette Buend ía-Roldán Source Type: research

Predictive factors for dose reduction and discontinuation of nintedanib in fibrotic interstitial lung diseases: Real life data
Nintedanib, an intracellular inhibitor targeting multiple tyrosine kinases, has emerged as a standard treatment for various fibrotic lung diseases. Despite its efficacy, side effects such as nausea, diarrhea, and hepatotoxicity often lead to dose reduction or discontinuation. In this retrospective analysis at a university hospital's interstitial lung disease clinic, we aimed to identify baseline characteristics associated with dose adjustment or treatment discontinuation. Of the 58 patients included, 41.4% maintained the full nintedanib dose, while 31.0% required dosage reduction, and 27.6% discontinued treatment due to ad...
Source: Respiratory Medicine - March 19, 2024 Category: Respiratory Medicine Authors: Emanuel Costa, Ana Rita Pedroso, Rita Matos, M árcio Cunha Rodrigues, Eva Padrão, Joana Sousa-Neves, Rui Rolo Tags: Short communication Source Type: research

Real respiratory infection risk in  primary Sjögren’s syndrome complicated with interstitial lung disease
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - March 18, 2024 Category: Rheumatology Source Type: research

Commentary on the respiratory infection risk in primary Sj ögren’s syndrome complicated with interstitial lung disease
(Source: Clinical Rheumatology)
Source: Clinical Rheumatology - March 18, 2024 Category: Rheumatology Source Type: research

Effectiveness and safety of eltrombopag in connective tissue disease patients with refractory immune thrombocytopenia: a retrospective study
CONCLUSIONS: Eltrombopag appears to be effective, safe and well-tolerated in refractory ITP patients with CTD; larger studies are needed to confirm the generalizability of these findings.PMID:38495431 | PMC:PMC10942842 | DOI:10.1093/rap/rkae029 (Source: Adv Data)
Source: Adv Data - March 18, 2024 Category: Epidemiology Authors: Xiangpin Jiang Xiaoming Shu Yongpeng Ge Source Type: research

Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research

Update on Sj ögren's syndrome : Diagnostics, treatment, and challenges
Z Rheumatol. 2024 Mar 18. doi: 10.1007/s00393-024-01493-z. Online ahead of print.ABSTRACTSjögren's syndrome (SjS) is the most common connective tissue disease with a prevalence of 1:200. Predominantly affecting women, SjS is associated with destruction of the exocrine glands, leading to xerophthalmia and xerostomia. In over 50% of patients, there are also extraglandular manifestations, leading to multiple organ manifestations including polyneuropathies and interstitial lung disease as well as symptoms such as fatigue and arthralgia. Diagnostic procedures include biomarkers, in particular anti-SS-A/Ro antibodies, histology...
Source: Zeitschrift fur Rheumatologie - March 18, 2024 Category: Rheumatology Authors: Nadine Zehrfeld Torsten Witte Diana Ernst Source Type: research

Safety and Effectiveness of Elotuzumab in Japanese Patients with Relapsed/Refractory Multiple Myeloma: A Post-marketing Surveillance Study
Conclusion This all-case post-marketing surveillance study showed that ELd had an acceptable tolerability profile and promising clinical activity in Japanese patients with RRMM.PMID:38494720 | DOI:10.2169/internalmedicine.2487-23 (Source: Internal Medicine)
Source: Internal Medicine - March 18, 2024 Category: Internal Medicine Authors: Fumiya Kaneko Hiroshi Suzuka Tomoaki Yoshino Ryosuke Hinosugi Source Type: research

Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research

Effectiveness and safety of eltrombopag in connective tissue disease patients with refractory immune thrombocytopenia: a retrospective study
CONCLUSIONS: Eltrombopag appears to be effective, safe and well-tolerated in refractory ITP patients with CTD; larger studies are needed to confirm the generalizability of these findings.PMID:38495431 | PMC:PMC10942842 | DOI:10.1093/rap/rkae029 (Source: Adv Data)
Source: Adv Data - March 18, 2024 Category: Epidemiology Authors: Xiangpin Jiang Xiaoming Shu Yongpeng Ge Source Type: research

Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research

Safety and Effectiveness of Elotuzumab in Japanese Patients with Relapsed/Refractory Multiple Myeloma: A Post-marketing Surveillance Study
Conclusion This all-case post-marketing surveillance study showed that ELd had an acceptable tolerability profile and promising clinical activity in Japanese patients with RRMM.PMID:38494720 | DOI:10.2169/internalmedicine.2487-23 (Source: Internal Medicine)
Source: Internal Medicine - March 18, 2024 Category: Internal Medicine Authors: Fumiya Kaneko Hiroshi Suzuka Tomoaki Yoshino Ryosuke Hinosugi Source Type: research

Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research