Lung adenocarcinoma discovered during the follow-up of lung-dominant connective tissue disease: a case report and literature review
Interstitial lung disease (ILD) can lead to lung cancer, which brings great challenges to differential diagnosis and comprehensive treatment. However, the clinical features of lung-dominant connective tissue d... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - April 12, 2024 Category: Respiratory Medicine Authors: Zi Heng Zhu, Yi Guo, Xiao Yin Wang and Xian Wen Sun Tags: Case Report Source Type: research

Correction: Nintedanib downregulates the profibrotic M2 phenotype in cultured monocyte-derived macrophages obtained from systemic sclerosis patients affected by interstitial lung disease
(Source: Arthritis Research and Therapy)
Source: Arthritis Research and Therapy - April 10, 2024 Category: Rheumatology Authors: Stefano Soldano, Vanessa Smith, Paola Montagna, Emanuele Gotelli, Rosanna Campitiello, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Andrea Cere and Maurizio Cutolo Tags: Correction Source Type: research

Assessing Time of Onset for Interstitial Lung Disease in Anti-MDA5 Antibody-Positive Dermatomyositis
This cohort study seeks to describe the time interval between interstitial lung disease and anti –melanoma differentiation-associated gene 5 antibody-positive dermatomyositis diagnoses. (Source: JAMA Dermatology)
Source: JAMA Dermatology - April 10, 2024 Category: Dermatology Source Type: research

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Interstitial Lung Disease
Am J Respir Crit Care Med. 2024 Apr 9. doi: 10.1164/rccm.202403-0603ED. Online ahead of print.NO ABSTRACTPMID:38593003 | DOI:10.1164/rccm.202403-0603ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 9, 2024 Category: Respiratory Medicine Authors: Yuben Moodley Source Type: research

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Interstitial Lung Disease
Am J Respir Crit Care Med. 2024 Apr 9. doi: 10.1164/rccm.202403-0603ED. Online ahead of print.NO ABSTRACTPMID:38593003 | DOI:10.1164/rccm.202403-0603ED (Source: Respiratory Care)
Source: Respiratory Care - April 9, 2024 Category: Respiratory Medicine Authors: Yuben Moodley Source Type: research

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Interstitial Lung Disease
Am J Respir Crit Care Med. 2024 Apr 9. doi: 10.1164/rccm.202403-0603ED. Online ahead of print.NO ABSTRACTPMID:38593003 | DOI:10.1164/rccm.202403-0603ED (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 9, 2024 Category: Intensive Care Authors: Yuben Moodley Source Type: research

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Interstitial Lung Disease
Am J Respir Crit Care Med. 2024 Apr 9. doi: 10.1164/rccm.202403-0603ED. Online ahead of print.NO ABSTRACTPMID:38593003 | DOI:10.1164/rccm.202403-0603ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - April 9, 2024 Category: Respiratory Medicine Authors: Yuben Moodley Source Type: research

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Interstitial Lung Disease
Am J Respir Crit Care Med. 2024 Apr 9. doi: 10.1164/rccm.202403-0603ED. Online ahead of print.NO ABSTRACTPMID:38593003 | DOI:10.1164/rccm.202403-0603ED (Source: Respiratory Care)
Source: Respiratory Care - April 9, 2024 Category: Respiratory Medicine Authors: Yuben Moodley Source Type: research

The Analysis of Proteomics by Machine Learning in Separating Idiopathic Pulmonary Fibrosis from Connective Tissue Disease-Interstitial Lung Disease
Am J Respir Crit Care Med. 2024 Apr 9. doi: 10.1164/rccm.202403-0603ED. Online ahead of print.NO ABSTRACTPMID:38593003 | DOI:10.1164/rccm.202403-0603ED (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - April 9, 2024 Category: Intensive Care Authors: Yuben Moodley Source Type: research

Revolutionizing the Treatment of Idiopathic Pulmonary Fibrosis: From Conventional Therapies to Advanced Drug Delivery Systems
This article elaborates on the pathophysiology of IPF, its risk factors, and different advanced drug delivery systems for treating IPF. Although extensive preclinical data is available for these delivery systems, the clinical performance and scale-up studies would decide their commercial translation.PMID:38589751 | DOI:10.1208/s12249-024-02793-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - April 8, 2024 Category: Drugs & Pharmacology Authors: Sanskriti Singh Sarika Wairkar Source Type: research

Revolutionizing the Treatment of Idiopathic Pulmonary Fibrosis: From Conventional Therapies to Advanced Drug Delivery Systems
This article elaborates on the pathophysiology of IPF, its risk factors, and different advanced drug delivery systems for treating IPF. Although extensive preclinical data is available for these delivery systems, the clinical performance and scale-up studies would decide their commercial translation.PMID:38589751 | DOI:10.1208/s12249-024-02793-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - April 8, 2024 Category: Drugs & Pharmacology Authors: Sanskriti Singh Sarika Wairkar Source Type: research

Evaluating Sensitization-Associated, Neuropathic-Like Symptoms and Psychological Factors in Patients with Interstitial Lung Disease
The aims of this study were to phenotype pain in patients with interstitial lung disease (ILD) by investigating the association between sensitization-associated symptoms with quality of life, anxiety/depression, pain catastrophizing and kinesiophobia levels, and, identifying those risk factors explaining the variance of quality of life in individuals with ILD and pain. One hundred and thirty-two (38.6% women, mean age: 70, SD: 10.5 years) patients with ILD completed clinical (age, sex, height, weight), psychological (Hospital Anxiety and Depression Scale, HADS and the Pittsburgh Sleep Quality Index, PSQI), and health-relat...
Source: The Journal of Pain - April 7, 2024 Category: Materials Science Authors: Paula Par ás-Bravo, César Fernández-de-las-Peñas, Diego Ferrer-Pargada, Patricia Druet-Toquero, Luis M. Fernández-Cacho, José M. Cifrián-Martínez, Lars Arendt-Nielsen, Manuel Herrero-Montes Source Type: research

A composite score based on cardiovascular parameters can predict the mortality risk of patients with newly diagnosed interstitial lung disease: A prospective observational study
CONCLUSIONS: A composite score based on cardiovascular parameters and the GAP score can be used to predict the risk of mortality of patients with ILD. Such a score achieved better diagnostic accuracy than the GAP score alone. Nevertheless, further larger-scale randomized controlled trials are required for evaluation of the newly proposed score and confirmation of our results.PMID:38582493 | DOI:10.1016/j.jjcc.2024.03.012 (Source: Journal of Cardiology)
Source: Journal of Cardiology - April 6, 2024 Category: Cardiology Authors: Yu-Wei Chen Chih-Hung Lai Yu-Wan Liao Ming-Cheng Liu Yu-Cheng Wu Chiann-Yi Hsu Yi-Hsuan Yu Pin-Kuei Fu Source Type: research

Volume changes of diseased and normal areas in progressive fibrosing interstitial lung disease on inspiratory and expiratory computed tomography
ConclusionThe diseased lung in PF-ILD retained expansion capacity comparable to the normal lung, suggesting a negative impact on respiratory function. (Source: Japanese Journal of Radiology)
Source: Japanese Journal of Radiology - April 6, 2024 Category: Radiology Source Type: research

The proportion of CD161 on CD56+ NK cells in peripheral circulation associates with clinical features and disease activity of primary Sj ögren's syndrome
ConclusionThis study suggested that the proportion of CD56+ NK cells and CD161+CD56+ NK cells decreased significantly in pSS patients, and the proportion of CD161+CD56+ NK cells negatively associated with the clinical features and disease activity of pSS patients. CD161 expression inhibited the function of CD56+ NK cells in peripheral blood of pSS patients. The CD161+CD56+ NK cells may present as a potential target for therapy and a biomarker of disease activity in pSS. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 5, 2024 Category: Allergy & Immunology Authors: Ping Zhao, Yanhong Yang, Saizhe Song, Wei Cheng, Cheng Peng, Xin Chang, Jian Wu, Cuiping Liu Tags: ORIGINAL ARTICLE Source Type: research