Safety and Effectiveness of Elotuzumab in Japanese Patients with Relapsed/Refractory Multiple Myeloma: A Post-marketing Surveillance Study
Conclusion This all-case post-marketing surveillance study showed that ELd had an acceptable tolerability profile and promising clinical activity in Japanese patients with RRMM.PMID:38494720 | DOI:10.2169/internalmedicine.2487-23 (Source: Internal Medicine)
Source: Internal Medicine - March 18, 2024 Category: Internal Medicine Authors: Fumiya Kaneko Hiroshi Suzuka Tomoaki Yoshino Ryosuke Hinosugi Source Type: research
Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research
Safety and Effectiveness of Elotuzumab in Japanese Patients with Relapsed/Refractory Multiple Myeloma: A Post-marketing Surveillance Study
Conclusion This all-case post-marketing surveillance study showed that ELd had an acceptable tolerability profile and promising clinical activity in Japanese patients with RRMM.PMID:38494720 | DOI:10.2169/internalmedicine.2487-23 (Source: Internal Medicine)
Source: Internal Medicine - March 18, 2024 Category: Internal Medicine Authors: Fumiya Kaneko Hiroshi Suzuka Tomoaki Yoshino Ryosuke Hinosugi Source Type: research
Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research
Safety and Effectiveness of Elotuzumab in Japanese Patients with Relapsed/Refractory Multiple Myeloma: A Post-marketing Surveillance Study
Conclusion This all-case post-marketing surveillance study showed that ELd had an acceptable tolerability profile and promising clinical activity in Japanese patients with RRMM.PMID:38494720 | DOI:10.2169/internalmedicine.2487-23 (Source: Internal Medicine)
Source: Internal Medicine - March 18, 2024 Category: Internal Medicine Authors: Fumiya Kaneko Hiroshi Suzuka Tomoaki Yoshino Ryosuke Hinosugi Source Type: research
Clinical and serological characteristics of anti-Ro/SS-A and anti-La/SS-B negative primary Sj ögren's syndrome: a comparative study
CONCLUSIONS: We confirm the strong influence of immunological markers on the phenotype of primary SS at diagnosis.PMID:38497858 | DOI:10.26355/eurrev_202403_35589 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 18, 2024 Category: Drugs & Pharmacology Authors: E Bodak çi Source Type: research
CD32 (Fc γRIIB) expression is low on CD21 < sup > low < /sup > B cells from systemic sclerosis patients with digital ulcers, interstitial lung disease, and anti-topoisomerase I autoantibodies
Clin Immunol. 2024 Mar 15:110195. doi: 10.1016/j.clim.2024.110195. Online ahead of print.ABSTRACTCD21low B cells have recently been found increased in SSc-associated digital ulcers (DUs) or interstitial lung disease (ILD). To further characterize CD21low B cells which encompass autoreactive cells, we analyzed their expression of the inhibitory CD32 receptor in SSc. Peripheral blood mononuclear cells from 27 patients with SSc and 15 age-and sex-matched healthy controls (HCs) were analyzed with multicolor flow cytometry. CD21low B cells were significantly increased in patients with DUs (51.3%) compared to HCs (28.1%) and in ...
Source: Clinical Immunology - March 17, 2024 Category: Allergy & Immunology Authors: Evangeli Kourkouni Sotirios G Tsiogkas Athanasios Mavropoulos Theodora Simopoulou Christina G Katsiari Dimitrios P Bogdanos Lazaros I Sakkas Source Type: research
CD32 (Fc γRIIB) expression is low on CD21 < sup > low < /sup > B cells from systemic sclerosis patients with digital ulcers, interstitial lung disease, and anti-topoisomerase I autoantibodies
Clin Immunol. 2024 Mar 15:110195. doi: 10.1016/j.clim.2024.110195. Online ahead of print.ABSTRACTCD21low B cells have recently been found increased in SSc-associated digital ulcers (DUs) or interstitial lung disease (ILD). To further characterize CD21low B cells which encompass autoreactive cells, we analyzed their expression of the inhibitory CD32 receptor in SSc. Peripheral blood mononuclear cells from 27 patients with SSc and 15 age-and sex-matched healthy controls (HCs) were analyzed with multicolor flow cytometry. CD21low B cells were significantly increased in patients with DUs (51.3%) compared to HCs (28.1%) and in ...
Source: Clinical Immunology - March 17, 2024 Category: Allergy & Immunology Authors: Evangeli Kourkouni Sotirios G Tsiogkas Athanasios Mavropoulos Theodora Simopoulou Christina G Katsiari Dimitrios P Bogdanos Lazaros I Sakkas Source Type: research
CD32 (Fc γRIIB) expression is low on CD21 < sup > low < /sup > B cells from systemic sclerosis patients with digital ulcers, interstitial lung disease, and anti-topoisomerase I autoantibodies
Clin Immunol. 2024 Mar 15:110195. doi: 10.1016/j.clim.2024.110195. Online ahead of print.ABSTRACTCD21low B cells have recently been found increased in SSc-associated digital ulcers (DUs) or interstitial lung disease (ILD). To further characterize CD21low B cells which encompass autoreactive cells, we analyzed their expression of the inhibitory CD32 receptor in SSc. Peripheral blood mononuclear cells from 27 patients with SSc and 15 age-and sex-matched healthy controls (HCs) were analyzed with multicolor flow cytometry. CD21low B cells were significantly increased in patients with DUs (51.3%) compared to HCs (28.1%) and in ...
Source: Clinical Immunology - March 17, 2024 Category: Allergy & Immunology Authors: Evangeli Kourkouni Sotirios G Tsiogkas Athanasios Mavropoulos Theodora Simopoulou Christina G Katsiari Dimitrios P Bogdanos Lazaros I Sakkas Source Type: research
A novel therapy for intractable chronic cough
Two cases of intractable chronic cough improved significantly with humidified high flow therapy (HHFT). The mechanisms by which HHFT improve intractable cough may include reducing airway dryness, inhibition of neutrophil inflammation and mucus obstruction, and splinting of the airways. HHFT significantly improved cough and health-related quality of life in two patients with interstitial lung disease. Further research is warranted to explore the role of domiciliary HHFT. AbstractTwo cases of intractable chronic cough improved significantly with humidified high flow therapy (HHFT). A 59-year-old woman with Primary Sjogren's ...
Source: Respirology Case Reports - March 16, 2024 Category: Respiratory Medicine Authors: Matthew Bricknell,
Chris Zi ‐Fan Zhao,
Natasha Smallwood,
Nicole Goh Tags: CASE REPORT Source Type: research
