Tocilizumab May Improve Lung Function in Early Systemic Sclerosis Tocilizumab May Improve Lung Function in Early Systemic Sclerosis
Treatment with tocilizumab could stabilize or improve lung function in people with early interstitial lung disease associated with systemic sclerosis.Medscape Medical News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - February 19, 2021 Category: Dermatology Tags: Rheumatology News Source Type: news
Lung Disease Raises Mortality Risk in Older RA Patients Lung Disease Raises Mortality Risk in Older RA Patients
RA-associated interstitial lung disease has been associated with worse survival rates as well as reduced quality of life, functional impairment, and increased health care use and costs.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - January 28, 2021 Category: Consumer Health News Tags: Rheumatology News Source Type: news
FDA grants priority review to Roche ’s Esbriet (pirfenidone) for unclassifiable interstitial lung disease
Basel, 21 January 2021 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the US Food and Drug Administration (FDA) has accepted the company ’s supplemental New Drug Application (sNDA) and granted Priority Review for Esbriet® (pirfenidone) for the treatment of unclassifiable interstitial lung disease (UILD). The FDA is expected to make a decision on approval by May 2021.“Since its US approval, Esbriet has become a standard of care for people living with idiopathic pulmonary fibrosis. However, significant unmet need remains in fibrotic lung diseases, including unclassifiable interstitial lung disease (UILD),” ...
Source: Roche Investor Update - January 21, 2021 Category: Pharmaceuticals Source Type: news
Inhaled Treprostinil Beneficial in Pulmonary Hypertension
Exercise capacity improved, clinical worsening reduced for patients with pulmonary HTN due to interstitial lung disease (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - January 14, 2021 Category: Respiratory Medicine Tags: Cardiology, Pharmacy, Pulmonology, Journal, Source Type: news
Inhaled Treprostinil Beneficial in Pulmonary Hypertension
THURSDAY, Jan. 14, 2021 -- Inhaled treprostinil improves exercise capacity in patients with pulmonary hypertension due to interstitial lung disease, according to a study published online Jan. 13 in the New England Journal of Medicine.
Aaron Waxman,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 14, 2021 Category: Pharmaceuticals Source Type: news
CT helps clinicians predict emphysema progression
The pattern of parenchymal emphysema on baseline CT scans forecasts progression...Read more on AuntMinnie.comRelated Reading:
Deep-learning algorithm detects free air on CT images
Machine learning boosts chest CT's performance
CT textures predict interstitial lung disease survival
COVID-19 patients face higher risk of barotrauma
CT helps predict TAVR outcomes (Source: AuntMinnie.com Headlines)
Source: AuntMinnie.com Headlines - December 18, 2020 Category: Radiology Source Type: news
Study connects diabetes, air pollution to interstitial lung disease
(Michigan State University) People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate. These findings are especially important today in the midst of the COVID-19 pandemic, where there is a heightened concern for the convergence of health effects from air pollution and SARS-CoV-2 in susceptible populations. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2020 Category: International Medicine & Public Health Source Type: news
Home oxygen therapy for adults with COPD and ILD: New ATS clinical practice guideline
(American Thoracic Society) The latest clinical practice guideline on home oxygen therapy addresses long-term and ambulatory oxygen therapy for adults with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) and includes the most comprehensive review of the evidence of any oxygen guideline to date. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 17, 2020 Category: International Medicine & Public Health Source Type: news
Interstitial Lung Disease
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 12, 2020 Category: General Medicine Source Type: news
Interstitial Lung Disease (Interstitial Pneumonia)
Title: Interstitial Lung Disease (Interstitial Pneumonia)Category: Diseases and ConditionsCreated: 11/10/2014 12:00:00 AMLast Editorial Review: 11/12/2020 12:00:00 AM (Source: MedicineNet Lungs General)
Source: MedicineNet Lungs General - November 12, 2020 Category: Respiratory Medicine Source Type: news
Pregnancy Can Be Safe With Interstitial Lung Disease Pregnancy Can Be Safe With Interstitial Lung Disease
Often women with ILD related to an autoimmune disease are advised to avoid conception or terminate their pregnancy. But the largest study to date on the subject draws more optimistic conclusions.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 8, 2020 Category: Consumer Health News Tags: Rheumatology News Source Type: news
Interstitial lung disease associated with systemic sclerosis large burden
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - November 1, 2020 Category: Drugs & Pharmacology Source Type: news
InPedILD_trial_enrollment
Phase III InPedILD ™ trial enrolls first patient to evaluate nintedanib in pediatric population with fibrosing interstitial lung diseaseFirst-of-its-kind clinical trial in children and adolescents with fibrosing interstitial lung disease (ILD) initiated globallyThis new study builds on the Phase III INBUILD ® trial and approval of Ofev® in adult patients with fibrosing ILDs with a progressive phenotype1,2,3Global Phase III multicentre clinical trial is planned to be conducted in approximately 70 sites in 24 countries (Source: Boehringer Ingelheim Corporate News)
Source: Boehringer Ingelheim Corporate News - August 12, 2020 Category: Research Source Type: news
Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration
The oxidation of tyrosine residues to generate o,o'-dityrosine cross-links in extracellular proteins is necessary for the proper function of the extracellular matrix (ECM) in various contexts in invertebrates. Tyrosine oxidation is also required for the biosynthesis of thyroid hormone in vertebrates, and there is evidence for oxidative cross-linking reactions occurring in extracellular proteins secreted by myofibroblasts. The ECM protein fibronectin circulates in the blood as a globular protein that dimerizes through disulfide bridges generated by cysteine oxidation. We found that cellular (fibrillar) fibronectin on the su...
Source: Signal Transduction Knowledge Environment - August 10, 2020 Category: Science Authors: Locy, M. L., Rangarajan, S., Yang, S., Johnson, M. R., Bernard, K., Kurundkar, A., Bone, N. B., Zmijewski, J. W., Byun, J., Pennathur, S., Zhou, Y., Thannickal, V. J. Tags: STKE Research Articles Source Type: news
ATS Issues Guide for Diagnosing Hypersensitivity Pneumonitis
Systematic approach developed for diagnosis of nonfibrotic, fibrotic HP in interstitial lung disease (Source: Pulmonary Medicine News - Doctors Lounge)
Source: Pulmonary Medicine News - Doctors Lounge - August 5, 2020 Category: Respiratory Medicine Tags: Pathology, Pulmonology, Radiology, Allergy, Journal, Source Type: news
