Pharmacist-Driven Stress Ulcer Prophylaxis Minimization in the Intensive Care Unit
Conditions: Stress Ulcer Interventions: Behavioral: To evaluate the effectiveness and safety of a pharmacist-driven protocol to discontinue stress ulcer prophylaxis in ICU patients when it is no longer indicated according to pre-defined criteria. Sponsors: Methodist Health System Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials
Detailed statistical analysis plan for ALBINO: effect of Allopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome — a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III)
DiscussionThe statistical analysis for the ALBINO study was defined in detail in the study protocol and implemented in this statistical analysis plan published prior to any data analysis. This is in accordance with the Declaration of Helsinki and the International Conference on Harmonization Good Clinical Practice guidelines.Trial registrationClinicalTrials.gov NCT03162653. Registered on 22 May 2017. (Source: Trials)
Source: Trials - January 24, 2024 Category: Research Source Type: clinical trials
Efficacy of ultrasound-guided erector spinae plane block on analgesia and quality of recovery after minimally invasive direct coronary artery bypass surgery: protocol for a randomized controlled trial
DiscussionThis is a novel randomized controlled study evaluating a preoperative ultrasound-guided single-shot unilateral ESPB on analgesia and quality of patient recovery in MIDCAB surgery. The results of this study will characterize the degree of acute postoperative pain and clinical outcomes following MIDCAB. Our study may help optimizing analgesia regimen selection and improving patient comfort in this specific population.Trial registrationThe study was prospectively registered with the Chinese Clinical Trial Registry (trial identifier: ChiCTR2100052810). Date of registration: November 5, 2021. (Source: Trials)
Source: Trials - January 19, 2024 Category: Research Source Type: clinical trials
Efficacy of End-of-life Communication Strategies on Nurses in the Intensive Care Unit
Conditions: Palliative Care Interventions: Other: communication strategy Sponsors: Maebashi Red Cross Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
IMT Outcomes in Sufferers of Severe Walking Disabilities and Intensive Care Unit Acquired Weakness
Conditions: Intensive Care Unit Acquired Weakness Interventions: Behavioral: Threshold IMT and traditional physical therapy program; Behavioral: traditional physiotherapy program Sponsors: Cairo University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Intensive Care Unit Procedure Related Infections
Conditions: Infections Interventions: Other: monitor signs of infection Sponsors: Cairo University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Hammock Position and Nesting in the Neonatal Intensive Care Unit
Conditions: Behavior, Nesting; Behavior, Child Interventions: Behavioral: Hammock Position; Behavioral: Nesting Sponsors: Maltepe University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Post Intubation Laryngeal Hazards in Children in the Pediatric Intensive Care Unit
Conditions: Laryngeal Injury Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study
Conditions: Oral Bacterial Infection; Mechanical Ventilation Complication Interventions: Device: SwishKit + Oral care treatment as usual; Procedure: Oral care treatment as usual Sponsors: The Cleveland Clinic; Swiftsure Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials
Continuous Glucose Monitoring in the Intensive Care Unit
Conditions: Diabetes Mellitus Interventions: Diagnostic Test: Dexcom G7 Continuous Glucose Monitor Sponsors: University of Massachusetts, Worcester Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials
Factors for Impairment of Renal Graft Function in Intensive Care
Conditions: Graft Failure; Dialysis; Chronic Kidney Failure Sponsors: Central Hospital, Nancy, France Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials
Efficacy and safety of heparin for sepsis-induced disseminated intravascular coagulation (HepSIC): study protocol for a multicenter randomized controlled trial
DiscussionThe HepSIC trial is to evaluate the efficacy and safety of UFH on sepsis-related DIC across different areas of China. The small dosage of UFH administration would offer a new potential approach for treating sepsis-related coagulation disorders.Ethics and disseminationEthical approval was granted by all the ethics committees of 20 participant centers. Results will be disseminated via peer-reviewed publications and presented at conferences.Trial registrationClinicalTrials.gov NCT02654561. Registered on 13 January 2016. (Source: Trials)
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials
Improving Outcomes in PICS With Home-Based Program of Rehabilitation and Health Coaching
Conditions: Post-Intensive Care Syndrome Interventions: Behavioral: Home-based Physical Rehabilitation; Behavioral: Health Coaching Sponsors: Mayo Clinic Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials
Predictors of Mortality in Traumatic Brain Injury Patients in Intensive Care Unit
Conditions: Brain Injuries, Traumatic Interventions: Other: hospitalisation for more than 24 hours in the 3rd stage Anesthesiology and Reanimation unit Sponsors: Umraniye Education and Research Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 28, 2023 Category: Research Source Type: clinical trials
Anticipating Decline and Providing Therapy
Conditions: Cognitive Impairment; Dementia; Post ICU Syndrome; Critical Illness; Cognitive Impairment, Mild Interventions: Behavioral: Usual Care post-Intensive Care Unit (ICU); Behavioral: Anticipating Decline and Providing Therapy (ADAPT) Sponsors: Wake Forest University Health Sciences; National Institute on Aging (NIA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 27, 2023 Category: Research Source Type: clinical trials
