Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic Control
Conditions: Type2diabetes Interventions: Drug: Insulin Glargine 100 UNT/ML Pen Injector [Lantus]; Drug: Saxagliptin 2.5 mg/ Metformin Hydrochloride extended release 1000 mg; Drug: Pioglitazone 30mg Sponsors: University of Basrah Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 30, 2023 Category: Research Source Type: clinical trials
The effects of intermittent fasting diet alone or in combination with probiotic supplementation in comparison with calorie-restricted diet on metabolic and hormonal profile in patients with polycystic ovary syndrome: study protocol for a randomized clinical trial
DiscussionWe hypothesized that 10-h TRE administered alone or in combination with probiotic supplementation to overweight and obese PCOS subjects would lead to weight loss and improved metabolic, hormonal, inflammatory, and antioxidant markers compared to control subjects following a standard 3-meal-per-day CR diet.Ethical aspectsThe current trial received approval from the Medical Ethics Committee of Tehran University of Medical Sciences, Tehran, Iran (IR.TUMS.MEDICNE.REC.1401.425).Trial registrationIranian Registry of Clinical Trials IRCT20121110011421N5. Registered on 3 October 2022. (Source: Trials)
Source: Trials - October 25, 2023 Category: Research Source Type: clinical trials
Digital Exercise for Middle-Aged Adults With Type 1 Diabetes and Other Absolute Insulin Deficiency Diabetes
Conditions: Type 1 Diabetes; Latent Autoimmune Diabetes in Adults; Pancreatitis Interventions: Behavioral: Digital Exercise Sponsors: Yale University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Exerscrip LLC Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 24, 2023 Category: Research Source Type: clinical trials
Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance
Conditions: Hypothyroidism; Insulin Resistance Interventions: Drug: Metformin Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 23, 2023 Category: Research Source Type: clinical trials
The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome in Insulin-resistant Women - a 12-week Randomized, Placebo-controlled, Double-blind Study
Conditions: Insulin Resistance Interventions: Dietary Supplement: the group GS (probiotic); Dietary Supplement: the group GP (placebo) Sponsors: Poznan University of Physical Education Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 20, 2023 Category: Research Source Type: clinical trials
Dual-hormone Artificial Pancreas Versus Single-hormone Under Exercise and a Meal Challenge
Conditions: Type 1 Diabetes Interventions: Device: Automated insulin delivery system algorithm with a dual-hormone configuration (insulin and glucagon) for glucose control; Device: Automated insulin delivery system with a single-hormone configuration (insulin) with rescue carbohydrate recommendations for glucose control Sponsors: Fundaci ón para la Investigación del Hospital Clínico de Valencia; Universitat Politècnica de València Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 13, 2023 Category: Research Source Type: clinical trials
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance
Conditions: Mitochondrial Myopathies; Mitochondrial Diseases; Mitochondrial Disorders Interventions: Behavioral: High-intensity exercise training Sponsors: Rigshospitalet, Denmark; University of Copenhagen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Mitochondrial Dysfunctions Driving Insulin Resistance
Conditions: Mitochondrial Myopathies; Mitochondrial Diseases; Mitochondrial Disorders Sponsors: Rigshospitalet, Denmark; University of Copenhagen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Does Biological Sex Influence Insulin Sensitivity and Muscle Metabolism Following High-intensity Interval Exercise?
Conditions: Exercise Interventions: Other: Seated Rest (Non-exercise control); Other: High-intensity interval exercise Sponsors: University of Toronto Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials
COMMETS- Combination MCI Metabolic Syndrome
Conditions: Alzheimer Disease; Mild Cognitive Impairment; Metabolic Syndrome Interventions: Drug: Semaglutide; Drug: Intranasal insulin; Other: Semaglutide placebo; Other: Intranasal insulin placebo Sponsors: Rutgers, The State University of New Jersey; Alzheimer ' s Association Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 9, 2023 Category: Research Source Type: clinical trials
Changes in Serum, Follicular Fluid SREBP1c and LRG1 Levels in PCOS Patients and Correlation With Insulin Resistance
Conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries Interventions: Diagnostic Test: HOMA-IR ，ESHRE/ASRM Sponsors: Gui Xiaoting Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials
Effect of Celery Seed on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Conditions: Metabolic Syndrome Interventions: Drug: Celery Seed; Drug: Placebo Sponsors: University of Guadalajara Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 29, 2023 Category: Research Source Type: clinical trials
Effect of Timed-Restricted Eating on Metabolic Health
Conditions: Obesity; Non-Alcoholic Fatty Liver Disease; Insulin Resistance Interventions: Behavioral: Early time restricted eating; Behavioral: Late time restricted eating Sponsors: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Diabetesfonds Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 29, 2023 Category: Research Source Type: clinical trials
Examining the Effect of Mobile Application on Insulin Use Perception and Self-Management
Conditions: Type 2 Diabetes Treated With Insulin Interventions: Other: INS-MOBILE: Mobile Application Developed for Insulin Use Sponsors: Ege University; The Scientific and Technological Research Council of Turkey Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 29, 2023 Category: Research Source Type: clinical trials
Semaglutide GLP1 Agonists With Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus
Condition: Type 1 Diabetes Intervention: Drug: Semaglutide weekly injection Sponsor: Ministry of Health, Saudi Arabia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 27, 2023 Category: Research Source Type: clinical trials
