Looking across the glass door: a COVID-19 vigil
A small piece of lint is tickling my nose as I am desperately trying not to sneeze into the tight-fitting mask on my face. I know that I will not be able to adjust the mask as my gloves are sterile, and I am standing suspended over a patient’s body with my gloves patinaed withRead more …Looking across the glass door: a COVID-19 vigil originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 18, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/katarine-egressy" rel="tag" data-wpel-link="internal" > Katarine Egressy, MD, MPH < /a > < /span > Tags: Conditions COVID Critical Care Infectious Disease Source Type: blogs
We are the voice of reason, the scientific experts, and the advocates for our patients
These last two years have been extremely challenging for most health care professionals. Watching society challenge essential health and science principles that we have known to be fact has been difficult to bear. Being villainized, health care workers went from being hailed“health care heroes” to being the target of hate, violence, and disregard. TheseRead more …We are the voice of reason, the scientific experts, and the advocates for our patients originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 15, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/tomi-mitchell" rel="tag" data-wpel-link="internal" > Tomi Mitchell, MD < /a > < /span > Tags: Conditions COVID Infectious Disease Source Type: blogs
We ’re losing the war. No, not that one.
In the coming months, no one can predict with certainty what will happen with the war in Ukraine. But there’s one thing we do know for sure. The United States will soon reach an unthinkable milestone: One million Americans will have died of COVID-19. Over the last month, while many people were celebrating the rollbackRead more …We ’re losing the war. No, not that one. originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 15, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/max-blumberg" rel="tag" data-wpel-link="internal" > Max Blumberg, MD < /a > < /span > Tags: Physician COVID Infectious Disease Source Type: blogs
Incredible true stories of pioneer patients [PODCAST]
“It was probably in early 1803, as Jenner ’s fame swelled and more doctors were adopting vaccination, when Bell met a farmer with a curious story. The farmer’s name was Benjamin Jesty, from the Downshay farm in a nearby village. Seeing the growing practice of vaccination, Jesty was eager to tell his story and claimed heRead more …Incredible true stories of pioneer patients [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 10, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Infectious Disease Source Type: blogs
Fight Aging! Newsletter, April 11th 2022
In conclusion, plasma levels of IGHA2, APOA and HPT are associated with subclinical atherosclerosis independently of traditional risk factors and offers potential to predict this disease. The panel could improve primary prevention strategies in areas where imaging is not available.
A Lesser Diversity of Circulating Antibodies in the Aging Killifish Immune System
https://www.fightaging.org/archives/2022/04/a-lesser-diversity-of-circulating-antibodies-in-the-aging-killifish-immune-system/
Short-lived killifish are one of the more recently adopted animal models of aging. All such models are a trade-off bet...
Source: Fight Aging! - April 10, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Before taking Paxlovid, consider these drug interactions
FDA and Health Canada recently approved Paxlovid as an oral treatment option for mild-to-moderate COVID-19 who are at high risk of progression to severe COVID-19. It is a combination drug containing nirmatrelvir/ritonavir. Nirmatrelvir works by binding to SARS-CoV-2 3CL protease to ultimately stop viral replication. Ritonavir does not have any antiviral activity against COVID-19 butRead more …Before taking Paxlovid, consider these drug interactions originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 7, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/param-patel" rel="tag" > Param Patel, PharmD < /a > < /span > Tags: Meds COVID Infectious Disease Medications Source Type: blogs
Natural Killer Cell Dysfunction in the Aging of the Immune System
The immune system is a highly complex collection of many different types of specialized cells. As is usually the case in scientific research, some areas receive more attention than others, particularly in the context of aging, wherein funding is limited and there are fewer researchers focus on the topic. Of late natural killer cells have received more attention as a result of their role in clearance of senescent cells. Given that the research community has built the case that senescent cell accumulation is actually quite important in aging, finding out how and why the immune system fails to clear these cells in an aged tis...
Source: Fight Aging! - April 7, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Pathways: The Vaccine Science Issue
Cover of Pathways student magazine.
NIGMS is pleased to bring you Pathways: The Vaccine Science Issue [PDF], which explains how the messenger RNA (mRNA) vaccines for COVID-19 work and how they were developed. Building on years of research, scientists were able to create these vaccines, thoroughly test them, and get them to the public as quickly as possible—while still making sure they were safe and effective.
Pathways, designed for students in grades 6 through 12, aims to build awareness of basic biomedical science and its importance to health while inspiring careers in research. All materials in the collection ar...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 6, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness COVID-19 Infectious Diseases RNA Source Type: blogs
Spherical Nucleic Acid Vaccine Uses Structural Design to Improve Efficacy
A team at Northwestern University created a new type of nanoparticle-based vaccine that employs structure-function relationships during the design phase to maximize efficacy. Called a spherical nucleic acid (SNA) vaccine, the technology consists of globular DNA nanoparticles that contain a DNA sequence that can stimulate the immune system (ie. an adjuvant) and an inner portion containing an antigen, which in this case was the spike protein of the SARS‑CoV‑2 virus. Packaging the antigen and adjuvant together in this specific way resulted in impressive efficacy in a rodent model of severe COVID-19, with 100% of vaccinate...
Source: Medgadget - April 4, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Nanomedicine Public Health Source Type: blogs
To treat future COVID variants, we need more than vaccines [PODCAST]
“With government and industry working hand in hand, we can develop and stockpile monoclonal antibody therapeutics in anticipation of variants to come. We need to be thinking several moves ahead to keep ahead of variants so that stockpiles of therapies do not become obsolete as they have now. Our government needs to ensure the properRead more …To treat future COVID variants, we need more than vaccines [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 1, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast COVID Infectious Disease Source Type: blogs
Inside the race to conquer the COVID-19 pandemic [PODCAST]
“That year, 2020, U ğur told the crowd, would be the year BioNTech proved the doubters wrong. There was no time to lose. Soon after he’d finished his talk, Uğur hopped on a plane to Seattle, where he met with a team at the Bill& Melinda Gates Foundation, which had recently signed a $100 millionRead more …Inside the race to conquer the COVID-19 pandemic [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 30, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" > The Podcast by KevinMD < /a > < /span > Tags: Podcast COVID Infectious Disease Source Type: blogs
The Negative Impact of COVID-19 on the Enjoyment of Legal Freedoms
Alain Ebi Abangma (University of Buffalo), The Negative Impact of COVID-19 on the Enjoyment of Legal Freedoms, 9(3) Int ’l J. Soc. Sci. Humanities Research 467-471 (2021): Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. Most... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - March 28, 2022 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Fight Aging! Newsletter, March 28th 2022
In conclusion, we summarized here evidence for a novel therapeutic approach to exploit the incredible ability of mitochondria to engage multifaceted neuroprotective stress response triggered by partial complex I inhibition. This approach promises relief for multiple human conditions, and to promote healthy aging to delay the onset of neurogenerative diseases, AD in particular, where age is the greatest risk factor. There is a mounting body of evidence generated in model organisms and humans in support of the safety of chronic application of complex I inhibitors. However, a better understanding of the molecular mechanisms i...
Source: Fight Aging! - March 27, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Weekly Overseas Health IT Links – 26th March, 2022.
Here are a few I came across last week.Note: Each link is followed by a title and few paragraphs. For the full article click on the link above title of the article. Note also that full access to some links may require site registration or subscription payment.-----https://mhealthintelligence.com/news/55-of-telehealth-providers-frustrated-with-overblown-patient-expectations55% of Telehealth Providers Frustrated With Overblown Patient ExpectationsProviders also cited their ability to provide quality care and technical difficulties as among their top frustrations with telehealth, a new survey shows.ByAnuja VaidyaMarch 18, 202...
Source: Australian Health Information Technology - March 26, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Damage-Associated Molecular Patterns (DAMPs) in the Aging Retina
The immune system reacts to damaged and dying cells, as well as their debris. As the level of tissue damage rises with age, this pattern recognition contributes to increasing levels of chronic inflammation. That in turn causes further harm, changing cell behavior for the worse, degrading tissue structure and function. Inflammation in aging is an example of a process that is beneficial in the short term becoming harmful when sustained for the long term, a process that is beneficial in the youthful environment becoming actively harmful in the age-damaged environment.
Damage-associated molecular patterns (DAMPs) are ...
Source: Fight Aging! - March 25, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
