New option for H pylori treatment: Voquezna
 The Food and Drug Administration (FDA) has approved the following new medication for the treatment of Helicobacter pylori (H. pylori) infection in adults.:- Voquezna Triple Pak(vonoprazan, amoxicillin, clarithromycin)-Voquezna Dual Pak (vonoprazan, amoxicillin)Vonoprazan, which gives the name of the medication, is an oral small molecule potassium-competitive acid blocker.H. pylori eradication rates were84.7% and 78.5% with Voquezna Triple and Dual Pak, respectively.Voquezna Triple Pak is supplied as a carton containing 56-tablets and 56-capsules divided into 14 daily dose blister cards. Each daily blister card contai...
Source: Clinical Cases and Images - Blog - January 13, 2023 Category: Universities & Medical Training Tags: Infectious Diseases Source Type: blogs

A High Level View of Efforts to Modulate Inflammaging and Immunosenescence of the Aged Immune System
Change and disruption in the immune system is an important component of degenerative aging. Broadly, the immune system becomes ever more inflammatory (inflammaging) while also becoming ever less effective (immunosenescence). The immune system is not only responsible for defending against invasive pathogens and destroying errant cells, but it is also tightly integrated into the normal processes of tissue maintenance and operation. When immune cells become inflammatory, they abandon the range of tasks needed to keep tissues functional. Short-term inflammation is necessary in response to injury and infection, but unresolved, ...
Source: Fight Aging! - January 11, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Pharma – 2023 Health IT Predictions
As we head into 2023, we wanted to kick off the new year with a series of 2023 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  Check out our communities predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. Check out our community’s pharma predictions. Jesse Cugliotta, Global Industry GTM Lead, Healthcare & Life Sciences at Snowflake Industry investments in data platforms to enable decentra...
Source: EMR and HIPAA - January 9, 2023 Category: Information Technology Authors: John Lynn Tags: Health IT Company Healthcare IT 2023 Health IT Predictions Abrpo BrainCheck Doceree Harshit Jain Ian Chen Jesse Cugliotta Kimberly Powell Lance Hill Lauren Ohlsson Mike Montalto NVIDIA Ofer Sharon OncoHost PathAI Pharma Source Type: blogs

The worst illness this physician ever had
An excerpt from Fifty Years a Doctor: The Journey of Sickness and Health, Four Plagues and the Pandemic. Our favorite internist and chairman of the internal medicine department was lecturing us on sensitivity to patients’ suffering when they have a serious illness. He stressed that our sensitivity would increase as we got older and had Read more… The worst illness this physician ever had originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 7, 2023 Category: General Medicine Authors: Tags: Conditions Infectious Disease Source Type: blogs

Shawn Drew Gaillard to Direct GMCDB
I’m pleased to announce the selection of Shawn Drew Gaillard, Ph.D., as the new director of our Division of Genetics and Molecular, Cellular, and Developmental Biology (GMCDB). Shawn has been the acting director of the Division since February 2022. She will begin in this new role on January 15. Shawn joined GMCDB as chief of the Developmental and Cellular Processes Branch in 2019, overseeing grants focused on organismal response to environmental stressors. Prior to this role, she was the research training officer at the National Institute of Allergy and Infectious Diseases, and before that, she was a program director in ...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - January 4, 2023 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Director’s Messages Job Announcements NIGMS Staff News Source Type: blogs

Let teens self-consent to vaccines
I still remember the exhilaration I felt upon learning that my peers and I could finally return to our in-person classrooms. After a year of Zoom lectures, asynchronous exams, and more, the prospect of seeing each other again thrilled us. However, we had not anticipated the constant fear and uncertainty that would accompany this transition. Read more… Let teens self-consent to vaccines originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 1, 2023 Category: General Medicine Authors: Tags: Policy Infectious Disease Source Type: blogs

Answer to Case 706
 Answer to theParasite Case of the Week 706:Haycocknema perplexuminfectionWow, I am so impressed by the responses on this case! There are many helpful comments and links in the comment section of this blog which you may want to check out.Haycocknema perplexuminfection (haycocknematosis) is an extremely rare parasitic infection. There have only been 13 humans cases (including this one) reported to date. As Florida Fan noted, Blaine and I previously presented this case as a poster, and it has now been published inEmerging Infectious Diseases. You can read the articleHERE. The article describes the diagnostic features of...
Source: Creepy Dreadful Wonderful Parasites - January 1, 2023 Category: Parasitology Source Type: blogs

Measles: a preventable disease that is making a comeback
I see there has been yet another measles outbreak; at the time of writing, the count is 59 in central Ohio. All are either unvaccinated or not fully vaccinated. No doubt local pediatricians are being flooded with worried parents proffering their offspring for viewing with the statement, “Could this rash be measles, doctor?” This certainly Read more… Measles: a preventable disease that is making a comeback originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 30, 2022 Category: General Medicine Authors: Tags: Conditions Infectious Disease Pediatrics Source Type: blogs

When contentment falls short
Sliding toward another solstice, I feel myself yearning. I want the daylight to stay a little longer, soft like this, gentle warmth and lovely shadows, lazy breezes, the illusion of contentment. But I am not content. Or perhaps I am, but whereas I once thought contentment was the goal, the sentiment makes me uneasy now. Read more… When contentment falls short originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 24, 2022 Category: General Medicine Authors: Tags: Physician COVID Infectious Disease Source Type: blogs

Netflix for Drugs?
By KIM BELLARD A relative — obviously overestimating my healthcare expertise — asked my thoughts on The New York Times article Can a Federally Funded ‘Netflix Model’ Fix the Broken Market for Antibiotics? I had previously skimmed the article and was vaguely aware of the Pasteur Act that it discusses, but, honestly, my immediate reaction to the article was, gosh, that may not be a great analogy: do people realize what a tough year Netflix has had? I have to admit that I tend to stay away from writing about Big Pharma and prescription drugs, mainly because, in a US healthcare system that seems to pride i...
Source: The Health Care Blog - December 21, 2022 Category: Consumer Health News Authors: matthew holt Tags: The Business of Health Care Congress Kim Bellard Netflix Pharma Pharmaceutical industry Source Type: blogs

Republicanism is bad for your health . . .
 and might even kill you.Nancy Krieger and colleagues studied Covid-19 mortality rates and stress on hospital capacity in all 435 congressional districts, and its association with the political ideology of the relevant congresscritters and whether there was one-party control of state government. Abstract:MethodsWe analyzed observational cross-sectional data on COVID-19 mortality rates (age-standardized) and stress on hospital intensive care unit (ICU) capacity for all 435 US Congressional Districts (CDs) in a period of adult vaccine availability (April 2021 –March 2022). Political metrics comprised: (1) ideological ...
Source: Stayin' Alive - December 20, 2022 Category: American Health Source Type: blogs

A physician in denial after being diagnosed with COVID-19
Over the last three years, we have faced the original COVID-19, followed by Omicron, Delta, and monkeypox. It is apropos that on the third anniversary of COVID-19, we are facing the tripledemic of COVID, influenza, and RSV. After almost three years of not getting COVID-19, I started believing that my childhood fantasies about me being Read more… A physician in denial after being diagnosed with COVID-19 originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 11, 2022 Category: General Medicine Authors: Tags: Conditions COVID Infectious Disease Source Type: blogs

The Chemistry Clicked: Two NIGMS-Funded Researchers Receive Nobel Prize
Since its creation in 1962, NIGMS has supported the work of the recipients of 94 Nobel Prizes—44 in physiology or medicine and 50 in chemistry. NIGMS-funded investigators perform cutting-edge basic research that is foundational to understanding normal life processes and disease. Such important breakthroughs in chemistry and biology often fuel more focused research that, years later, leads to important medical advances or products such as medicines or biotechnology tools. Credit: Niklas Elmehed. The most recent NIGMS-supported Nobel laureates are Carolyn R. Bertozzi, Ph.D., the Anne T. and Robert M. Bass Professor in...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - December 7, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Tools and Techniques Cool Tools/Techniques Nobel Prize Profiles Source Type: blogs

“True, True, and Unrelated” in the age of “Product Placement/Embedded Marketing.”
BY MIKE MAGEE This is “high grandparenting season” at our home when you go “The Extra Mile.” That means it is possible on certain days on or between Thanksgiving and New Year’s Day to find up to 20 children and grandchildren under our roof. With my wife one of ten, and me, one of twelve, we are no strangers to chaos. Our kids believe we feed off it, and maybe they’re right. With over 150 years under our collective belts, we two are – if nothing else – optimistic, resilient, and somewhat wiser then we were in our early years. For example, we know that the mere temporal or geographic approximation of ...
Source: The Health Care Blog - November 30, 2022 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Embedded Marketing Mike Magee Product Placement Source Type: blogs

Dynamic Duo Degrees: NIGMS-Funded Programs Support M.D./D.V.M.-Ph.D. Training
Amelia Wilhelm. Credit: Courtesy of Amelia Wilhelm. “Being able to ground your research in questions coming directly from your patients and their families is so meaningful and a huge part of why I’m interested in becoming a clinician-scientist,” says Amelia Wilhelm, an M.D.-Ph.D. student in the NIGMS-supported Medical Scientist Training Program (MSTP) at the University of Washington in Seattle. MSTPs prepare students to combine clinical practice and rigorous scientific research in their future careers. Continuing the Family Tradition in Science As a child of two scientists, Amelia was exposed to research and ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 30, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Profiles Training Source Type: blogs