Induction of labor versus expectant management in patients with idiopathic polyhydramnios
CONCLUSION: Lower rates of cesarean section were associated with labor induction for patients with isolated polyhydramnios, but confidence intervals did not reach statistical significance.PMID:38039900 | DOI:10.1016/j.ejogrb.2023.11.031 (Source: Reproductive Biology)
Source: Reproductive Biology - December 1, 2023 Category: Reproduction Medicine Authors: Corina N Schoen Sami Backley Lauren Orr Amrita Roy Tiffany Corlin Alexander B Knee Source Type: research

EE425 Estimating HCP Labor Time and Cost Saving with the Use of Rapid Rituximab Infusions Versus Standard Rituximab Infusions for the Treatment of Adults with Follicular Lymphoma and Diffuse Large B-Cell Lymphoma in Induction Phase
Intense resource competition for chair time and nursing resources is common in hospitals. This also affects patients undergoing treatment with rituximab standard intravenous infusion (S-IV), which requires ∼240 mins to complete. To address this challenge, this research aimed to quantify the economic and organizational impact of 90-mins rituximab rapid IV infusion (R-IV) in comparison with S-IV on the utilization of healthcare professionals’ (HCP) time for the treatment of adults with follicular ly mphoma (FL) and diffuse large B-cell lymphoma (DLBCL), in the induction phase, in the United Kingdom (UK). (Source: Value in Health)
Source: Value in Health - December 1, 2023 Category: International Medicine & Public Health Authors: D. Finocchiaro, A. Goh, S. Gupta, L. Bittencourt da Silva, C. Groves Source Type: research

Transvaginal Ovarian Cyst Drainage in Third Trimester to Facilitate Vaginal Delivery
AJP Rep 2023; 13: e82-e84 DOI: 10.1055/a-2184-0548Adnexal masses in the third trimester of pregnancy may obstruct the pelvic outlet precluding labor induction and vaginal delivery. Expectant versus surgical management of adnexal cysts in pregnancy must carefully weigh maternal–fetal benefits and risks. Simple benign appearing cysts with low likelihood of malignancy may be amenable to percutaneous drainage as a bridge to interval postpartum laparoscopic cystectomy. We demonstrated posterior culdocentesis as a safe, minimally invasive technique to decompress a simple benign appearing left adnexal cyst obstructing the pelvi...
Source: American Journal of Perinatology Reports - November 28, 2023 Category: Perinatology & Neonatology Authors: Meljen, Vivienne T. Avram, Carmen M. Kerner, Nicole P. Rhee, Eleanor H. J. Kuller, Jeffrey A. Wheeler, Sarahn M. Tags: Case Report Source Type: research

GSE248415 C/EBP β-induced lymphoid-to-myeloid transdifferentiation emulates granulocyte-monocyte progenitor (GMP) biology
Contributors : Linh Nguyen ; Karin Zimmermann ; Elisabeth Kowenz-Leutz ; Ramonique Lim ; Maria Hofst ätter ; Alexander Mildner ; Achim LeutzSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe CCAAT/enhancer-binding-protein beta (C/EBP β) induces primary v-Abl immortalized mouse B cell transdifferentiation (BT) into granulocyte-macrophage-progenitor-like cells (GMPBT). GMPBT maintain cytokine independent self-renewal, lineage choice, and multi-lineage differentiation. Single cell transcriptomics now shows that GMPBT comprise a co ntinuum of myelomonopoietic differentiation sta...
Source: GEO: Gene Expression Omnibus - November 24, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

An Externally Validated Model to Predict Prolonged Induction of Labor with an Unfavorable Cervix
Conclusion Our externally validated model was efficient in predicting prolonged induction of labor with an unfavorable cervix. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - November 23, 2023 Category: Perinatology & Neonatology Authors: Kawakita, Tetsuya Saeed, Haleema Huang, Jim C. Tags: Original Article Source Type: research

Twice-daily versus once-daily vaginal dinoprostone gel for induction of labor at term: A randomized controlled trial
CONCLUSION: Among women admitted for induction of labor at term, closer interval of vaginal PGE2 administration was associated with a significantly shorter induction-to-delivery time without increasing maternal or neonatal morbidity. Furthermore, the reduction in induction time was associated with improved patient experience of delivery.PMID:37992422 | DOI:10.1016/j.ejogrb.2023.11.016 (Source: Reproductive Biology)
Source: Reproductive Biology - November 22, 2023 Category: Reproduction Medicine Authors: Marion David Henriette Paule Gueye M Moustapha Drame Jeanne Sibiude C écile Penager Eustase Janky Laurent Mandelbrot Najeh Hcini Source Type: research

Maternal Group B Streptococcus Prophylaxis Improvement using an Electronic Medical Record Dynamic Order Set
Conclusion Routine universal use of a dynamic admission labor/induction order set was associated with high and improved adherence to GBS prophylaxis guidelines. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - November 22, 2023 Category: Perinatology & Neonatology Authors: Tomlinson, Mark W. Baker, Rachael Ulrich, Jennifer Shah, Maulin Marginean, Horia Girolami, Stephen Tags: Original Article Source Type: research

Vaginal Compared With Oral Misoprostol Induction at Term: A Cluster Randomized Controlled Trial
CONCLUSION: Induction of labor with vaginal compared with oral misoprostol protocols did not increase the frequency of vaginal delivery at term but did reduce the need for oxytocin use before delivery.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04755218.PMID:37989142 | DOI:10.1097/AOG.0000000000005464 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 21, 2023 Category: OBGYN Authors: Emily H Adhikari Jennifer McGuire Julie Lo Donald D McIntire Catherine Y Spong David B Nelson Source Type: research

Vaginal Compared With Oral Misoprostol Induction at Term: A Cluster Randomized Controlled Trial
CONCLUSION: Induction of labor with vaginal compared with oral misoprostol protocols did not increase the frequency of vaginal delivery at term but did reduce the need for oxytocin use before delivery.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04755218.PMID:37989142 | DOI:10.1097/AOG.0000000000005464 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 21, 2023 Category: OBGYN Authors: Emily H Adhikari Jennifer McGuire Julie Lo Donald D McIntire Catherine Y Spong David B Nelson Source Type: research

Vaginal Compared With Oral Misoprostol Induction at Term: A Cluster Randomized Controlled Trial
CONCLUSION: Induction of labor with vaginal compared with oral misoprostol protocols did not increase the frequency of vaginal delivery at term but did reduce the need for oxytocin use before delivery.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04755218.PMID:37989142 | DOI:10.1097/AOG.0000000000005464 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 21, 2023 Category: OBGYN Authors: Emily H Adhikari Jennifer McGuire Julie Lo Donald D McIntire Catherine Y Spong David B Nelson Source Type: research

Vaginal Compared With Oral Misoprostol Induction at Term: A Cluster Randomized Controlled Trial
CONCLUSION: Induction of labor with vaginal compared with oral misoprostol protocols did not increase the frequency of vaginal delivery at term but did reduce the need for oxytocin use before delivery.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04755218.PMID:37989142 | DOI:10.1097/AOG.0000000000005464 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 21, 2023 Category: OBGYN Authors: Emily H Adhikari Jennifer McGuire Julie Lo Donald D McIntire Catherine Y Spong David B Nelson Source Type: research

Vaginal Compared With Oral Misoprostol Induction at Term: A Cluster Randomized Controlled Trial
CONCLUSION: Induction of labor with vaginal compared with oral misoprostol protocols did not increase the frequency of vaginal delivery at term but did reduce the need for oxytocin use before delivery.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04755218.PMID:37989142 | DOI:10.1097/AOG.0000000000005464 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 21, 2023 Category: OBGYN Authors: Emily H Adhikari Jennifer McGuire Julie Lo Donald D McIntire Catherine Y Spong David B Nelson Source Type: research

Vaginal Compared With Oral Misoprostol Induction at Term: A Cluster Randomized Controlled Trial
CONCLUSION: Induction of labor with vaginal compared with oral misoprostol protocols did not increase the frequency of vaginal delivery at term but did reduce the need for oxytocin use before delivery.CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT04755218.PMID:37989142 | DOI:10.1097/AOG.0000000000005464 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - November 21, 2023 Category: OBGYN Authors: Emily H Adhikari Jennifer McGuire Julie Lo Donald D McIntire Catherine Y Spong David B Nelson Source Type: research

Induction of Labor Versus Expectant Management in Patients with Idiopathic Polyhydramnios
Polyhydramnios is an excess volume of amniotic fluid and is estimated to complicate 1-2% of singleton pregnancies.[1,2] The Society of Maternal Fetal Medicine currently suggests that a maximum vertical pocket (MVP) of ≥8 cm or amniotic fluid index (AFI) ≥24 cm be used to meet the diagnostic criteria for polyhydramnios.[1] Although a majority of cases remain unexplained or are termed “idiopathic,” approximately 30-40% are due to underlying causes such as maternal diabetes or fetal anomalies.[1,2] Even when fetal anomalies, infection, maternal diabetes, and alloimmunization have been ruled out, polyhydramnios continu...
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - November 21, 2023 Category: OBGYN Authors: Corina N. Schoen, Sami Backley, Lauren Orr, Amrita Roy, Tiffany Corlin, Alexander B. Knee Tags: Full length article Source Type: research

Developing a nomogram for estimating the risk of needing to perform a caesarean section after induction of labour in pregnancies using a COOK ® Cervical Ripening Balloon
CONCLUSION: We successfully constructed a nomogram for caesarean delivery after IOL in pregnancies with CCRB treatment using factors including parity, modified Bishop score at induction and the artificial rupture of membrane.PMID:37980578 | DOI:10.3233/THC-230761 (Source: Technology and Health Care)
Source: Technology and Health Care - November 19, 2023 Category: Medical Devices Authors: Jing Gao Chao Zhang Hong Xin Source Type: research